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1. Full Text GW27-e0459 Attainment of acc/aha recommended ldl-c lowering with statin and ezetimibe+statin therapies
by Toth, Peter P and Bays, Harold and Farnier, Michel and Jensen, Erin and Tomassini, Joanne E and Polis, Adam and Foody, JoAnne and Tershakovec, Andrew M
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 16, pp. C136 - C137
  Objectives The ACC/AHA 2013 cholesterol guidelines do not specify lipid target levels, but rather treatment of patients classified by cardiovascular risk to... 
Cardiovascular | Internal Medicine | Low density lipoproteins | Statins | Atherosclerosis | Diabetes | Low density lipoprotein | Patients
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2. Full Text Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
by Cannon, Christopher P and Blazing, Michael A and Giugliano, Robert P and McCagg, Amy and White, Jennifer A and Theroux, Pierre and Darius, Harald and Lewis, Basil S and Ophuis, Ton Oude and Jukema, J. Wouter and De Ferrari, Gaetano M and Ruzyllo, Witold and De Lucca, Paul and Im, KyungAh and Bohula, Erin A and Reist, Craig and Wiviott, Stephen D and Tershakovec, Andrew M and Musliner, Thomas A and Braunwald, Eugene and Califf, Robert M and IMPROVW-IT Investigators and IMPROVE-IT Investigators
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Liver | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
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3. Full Text Reply: Adding Ezetimibe to Simvastatin for the Secondary Prevention of Cardiovascular Disease: Is it Useful?
by Murphy, Sabina A and Cannon, Christopher P and Blazing, Michael A and Giugliano, Robert P and Tershakovec, Andrew M and Braunwald, Eugene
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2016, Volume 67, Issue 25, pp. 3025 - 3026
  In response to Drs. Mascitelli and Goldstein, we previously reported in the primary publication of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin... 
Anticholesteremic Agents | Cardiovascular Diseases | Hypercholesterolemia | Humans | Simvastatin | Ezetimibe | Cholesterol, LDL | Secondary Prevention | Drug Therapy, Combination | Acute coronary syndromes | Mortality | Clinical outcomes
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4. Full Text Reply
by Murphy, Sabina A., MPH and Cannon, Christopher P., MD and Blazing, Michael A., MD and Giugliano, Robert P., MD and Tershakovec, Andrew M., MD, MPH and Braunwald, Eugene, MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 3, pp. 326 - 326
Cardiovascular | Internal Medicine
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5. Full Text Reply
by Murphy, Sabina A., MPH and Cannon, Christopher P., MD and Blazing, Michael A., MD and Giugliano, Robert P., MD and Tershakovec, Andrew M., MD, MPH and Braunwald, Eugene, MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 25, pp. 3025 - 3026
Cardiovascular | Internal Medicine
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6. Full Text GW26-e4473 Cholesterol in Remnant-Lipoproteins as Measured by Different Methods
by Toth, Peter P and Bays, Harold E and Brown, W Virgil and Tomassini, Joanne E and Wang, Colin and Polis, Adam B and Tershakovec, Andrew M
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 16, pp. C228 - C229
  Objectives Elevated remnant-lipoprotein cholesterol (RLP-C) levels are associated with an increased risk of ischemic heart disease. 
Cardiovascular | Internal Medicine | Cholesterol | Methods | Blood lipids | Agreements
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7. Full Text Reply
by Murphy, Sabina A and Cannon, Christopher P and Blazing, Michael A and Giugliano, Robert P and Tershakovec, Andrew M and Braunwald, Eugene
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2016, Volume 68, Issue 3, p. 326
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8. Full Text Reply
by Murphy, Sabina A and Cannon, Christopher P and Blazing, Michael A and Giugliano, Robert P and Tershakovec, Andrew M and Braunwald, Eugene
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2016, Volume 67, Issue 25, pp. 3025 - 3026
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9. Full Text Bayesian inference for network meta-regression using multivariate random effects with applications to cholesterol lowering drugs
by Li, Hao and Chen, Ming-Hui and Ibrahim, Joseph G and Kim, Sungduk and Shah, Arvind K and Lin, Jianxin and Tershakovec, Andrew M
Biostatistics (Oxford, England), ISSN 1465-4644, 07/2019, Volume 20, Issue 3, pp. 499 - 516
Low-density lipoprotein cholesterol (LDL-C) has been identified as a causative factor for atherosclerosis and related coronary heart disease, and as the main... 
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10. GW27-e0459 Attainment of acc/aha recommended ldl-c lowering with statin and ezetimibe+statin therapies: Hypertension
by Toth, Peter P and Bays, Harold and Farnier, Michel and Jensen, Erin and Tomassini, Joanne E and Polis, Adam and Foody, JoAnne and Tershakovec, Andrew M
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2016, Volume 68, Issue 16, pp. C136 - C137
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11. Full Text A comparison of the attainment of guideline-recommended LDL-C lowering with statin and ezetimibe+statin therapies
by Toth, Peter P and Bays, Harold and Farnier, Michel and Jensen, Erin and Tomassini, Joanne E and Polis, Adam and Lin, Jianxin and Bird, Steve and Foody, Joanne and Tershakovec, Andrew M
Atherosclerosis, ISSN 0021-9150, 08/2017, Volume 263, pp. e240 - e241
Cardiology | Comparative analysis | Low density lipoproteins | Statins
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12. Full Text Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18,144 patients after acute coronary syndromes: Final baseline characteristics of the IMPROVE-IT study population
by Blazing, Michael A., MD and Giugliano, Robert P., MD, SM and Cannon, Christopher P., MD and Musliner, Thomas A., MD and Tershakovec, Andrew M., MD, MPH and White, Jennifer A., MS and Reist, Craig, PhD and McCagg, Amy, BS and Braunwald, Eugene, MD and Califf, Robert M., MD
American Heart Journal, ISSN 0002-8703, 2014, Volume 168, Issue 2, pp. 205 - 212.e1
Background The IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) is evaluating the potential benefit for reduction in major... 
Cardiovascular | LDL CHOLESTEROL | PLUS EZETIMIBE | CARDIAC & CARDIOVASCULAR SYSTEMS | INTENSIVE STATIN THERAPY | EFFICACY | SAFETY | AORTIC-STENOSIS | CLINICAL-TRIALS | DISEASE | LOW-DENSITY-LIPOPROTEIN | PLACEBO-CONTROLLED TRIAL | Simvastatin - therapeutic use | Cardiovascular Diseases - drug therapy | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Ezetimibe | Cholesterol, LDL - drug effects | Male | Azetidines - pharmacology | Acute Coronary Syndrome - blood | Acute Coronary Syndrome - drug therapy | Acute Coronary Syndrome - complications | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Cardiovascular Diseases - epidemiology | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Anticholesteremic Agents - pharmacology | Medical research | Low density lipoproteins | Simvastatin | Cardiac patients | Medicine, Experimental | Coronary heart disease | Antilipemic agents | Heart attacks | Acute coronary syndromes | Drug therapy | Cholesterol | Statins
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