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PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0173329
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0160388
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy linked to a deficiency in the metalloprotease ADAMTS13. In the... 
VONWILLEBRAND-FACTOR | MYOCARDIAL-INFARCTION | VWF | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MICE | VON-WILLEBRAND-FACTOR | ISCHEMIC-STROKE | FACTOR-CLEAVING PROTEASE | UPSHAW-SCHULMAN SYNDROME | DEFICIENCY | Recombinant Proteins - therapeutic use | Epitope Mapping | Humans | Protein Multimerization | Antibodies, Monoclonal - therapeutic use | Male | von Willebrand Factor - genetics | Recombinant Proteins - biosynthesis | Antigen-Antibody Reactions | ADAMTS13 Protein - blood | Recombinant Proteins - isolation & purification | ADAMTS13 Protein - immunology | Purpura, Thrombotic Thrombocytopenic - drug therapy | Female | Antibodies, Monoclonal - immunology | Disease Models, Animal | Purpura, Thrombotic Thrombocytopenic - metabolism | von Willebrand Factor - metabolism | Reproducibility of Results | Enzyme-Linked Immunosorbent Assay | ADAMTS13 Protein - metabolism | Mice, Knockout | Antibodies, Monoclonal - genetics | Purpura, Thrombotic Thrombocytopenic - pathology | Animals | Platelet Count | Recombinant Proteins - immunology | von Willebrand Factor - chemistry | ADAMTS13 Protein - genetics | Mice | Antibodies, Monoclonal - metabolism | Viral antibodies | Thrombocytopenic purpura | Care and treatment | Von Willebrand factor | Antibodies | Physiological aspects | Genetic aspects | Research | Diagnosis | Thrombotic microangiopathy | Antigens | Animal models | Drug delivery systems | Congenital diseases | Heart attacks | Laboratories | Injection | Thrombosis | Blood clots | Thrombotic thrombocytopenic purpura | Ischemia | Rodents | Medical prognosis | Preeclampsia | Monoclonal antibodies | Life sciences | Metalloproteinase | Mutation | Inhibition | Health risk assessment | Enzyme-linked immunosorbent assay
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 01/2010, Volume 121, Issue 1, pp. 80 - 90
Journal Article
Expert Review of Clinical Pharmacology, ISSN 1751-2433, 06/2019, Volume 12, Issue 6, pp. 537 - 545
Introduction: Caplacizumab is a humanized anti-von Willebrand Factor (vWF) Nanobody® for the treatment of acquired Thrombotic Thrombocytopenic Purpura (aTTP).... 
Nanobod y | exposure-response relationship | aTTP | vWF | RICO | pharmacodynamics | pharmacokinetics | clinical pharmacology | Caplacizumab | Nanobody | exposure–response relationship | Index Medicus
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2017, Volume 117, Issue 1, pp. 19 - 26
Journal Article
Circulation, ISSN 0009-7322, 03/2014, Volume 129, Issue 12, pp. 1320 - 1331
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2012, Volume 16, Issue 9, pp. 2117 - 2126