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Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 443 - 456
The mechanisms underlying human natural killer (NK) cell phenotypic and functional heterogeneity are unknown. Here, we describe the emergence of diverse... 
NATURAL-KILLER-CELLS | ACTIVATION | CMV REACTIVATION | INNATE | RECEPTOR | FCR-GAMMA | DIFFERENTIATION | IMMUNOLOGY | PLZF CONTROLS | EXPRESSION | T-CELLS | Cell Proliferation | Humans | Transcription Factors - deficiency | NK Cell Lectin-Like Receptor Subfamily C - genetics | Receptors, IgG - deficiency | Intracellular Signaling Peptides and Proteins - immunology | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Killer Cells, Natural - pathology | Cytomegalovirus Infections - genetics | Protein-Tyrosine Kinases - deficiency | Protein-Tyrosine Kinases - immunology | T-Lymphocytes, Cytotoxic - pathology | Intracellular Signaling Peptides and Proteins - deficiency | NK Cell Lectin-Like Receptor Subfamily C - immunology | DNA Methylation | Protein-Tyrosine Kinases - genetics | Receptors, IgG - genetics | Microarray Analysis | Antibodies - immunology | Cytomegalovirus Infections - virology | Killer Cells, Natural - immunology | Cytomegalovirus Infections - pathology | Kruppel-Like Transcription Factors - deficiency | Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | Promoter Regions, Genetic | GPI-Linked Proteins - immunology | Signal Transduction | Killer Cells, Natural - virology | T-Lymphocytes, Cytotoxic - virology | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Immunophenotyping | Receptors, IgG - immunology | Transcription Factors - genetics | Killer Cells, Natural - classification | Promyelocytic Leukemia Zinc Finger Protein | Cytomegalovirus - immunology | Epigenesis, Genetic - immunology | Kruppel-Like Transcription Factors - genetics | Kruppel-Like Transcription Factors - immunology | GPI-Linked Proteins - genetics | Virus diseases | Proteins | Epigenetic inheritance | Killer cells | Immunotherapy | Genomics | Medical genetics | Cytomegalovirus infections | T cells | Methylation | Health aspects | Antigens | Flow cytometry | Cytomegalovirus | Data analysis | Biomedical research | Transplants & implants | Cytokines | Leukemia | Cytotoxicity | Infections | Kinases | Diversification | Gene expression | Experiments | Scholarships & fellowships | Lymphocytes | DNA methylation | Epigenetics | Viral infections | Immune system | Cancer | Index Medicus
Journal Article
Cancer, ISSN 0008-543X, 06/2019, Volume 125, Issue 11, pp. 1848 - 1854
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 256 - 263
The cytostatic deoxycytidine analog cytarabine (ara-C) is the most active agent available against acute myelogenous leukemia (AML). Together with... 
MEDICINE, RESEARCH & EXPERIMENTAL | CYTOSINE-ARABINOSIDE | CELLS | ARA-C SENSITIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | CELL BIOLOGY | IN-VITRO | DNA | CHRONIC LYMPHOCYTIC-LEUKEMIA | MUTATIONS | EXPRESSION | Cytarabine - pharmacology | Prognosis | Apoptosis - drug effects | Cytarabine - therapeutic use | Humans | Leukemia, Myeloid, Acute - metabolism | SAM Domain and HD Domain-Containing Protein 1 | Child, Preschool | Infant | Male | Viral Regulatory and Accessory Proteins - pharmacology | Molecular Targeted Therapy | Monomeric GTP-Binding Proteins - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Antimetabolites, Antineoplastic - pharmacology | Female | Child | Disease Models, Animal | Arabinofuranosylcytosine Triphosphate - metabolism | Antimetabolites, Antineoplastic - therapeutic use | Animals | Monomeric GTP-Binding Proteins - metabolism | Adolescent | Aged | Mice | In Vitro Techniques | Cellular proteins | Molecular targeted therapy | Care and treatment | Cytarabine | Patient outcomes | Drug interactions | Innovations | Development and progression | Genetic aspects | Blood diseases | Health aspects | Biomarkers | Cytotoxicity | Chemotherapy | Gene expression | Leukemia | Index Medicus | Biological Sciences | Clinical Medicine | Naturvetenskap | Medical and Health Sciences | Hematology | Hematologi | Medicin och hälsovetenskap | Biologiska vetenskaper | Natural Sciences | Klinisk medicin
Journal Article
Blood, ISSN 0006-4971, 07/2018, Volume 132, Issue 1, pp. 5 - 7
In this issue of Blood, Chinn et al report genetic findings in a large cohort of children with hemophagocytic lymphohistiocytosis (HLH), indicating that many... 
HEMATOLOGY | HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | MUTATION | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 7/2016, Volume 36, Issue 5, pp. 480 - 489
Autosomal recessive mutations in LRBA, encoding for LPS-responsive beige-like anchor protein, were described in patients with a common variable... 
Medical Microbiology | Biomedicine | Immunology | common variable immune deficiency | enteropathy | primary immunodeficiency | hematopoietic stem cell transplantation | acute disseminated encephalomyelitis | Infectious Diseases | Internal Medicine | whole exome sequencing | BONE-MARROW-TRANSPLANTATION | COMMON VARIABLE IMMUNODEFICIENCY | T-CELL | IMMUNOLOGY | DEFICIENCY | IMMUNE DYSREGULATION | DISEASE | DISORDER | POLYENDOCRINOPATHY | Autoimmunity | Humans | HLA Antigens - immunology | Hematopoietic Stem Cell Transplantation | Common Variable Immunodeficiency - genetics | Male | Treatment Outcome | Anemia, Hemolytic, Autoimmune - genetics | Common Variable Immunodeficiency - diagnosis | B-Lymphocytes - immunology | Anemia, Hemolytic, Autoimmune - therapy | Common Variable Immunodeficiency - therapy | DNA Mutational Analysis | Adaptor Proteins, Signal Transducing - genetics | Immunoglobulins - blood | Killer Cells, Natural - immunology | Anemia, Hemolytic, Autoimmune - diagnosis | Consanguinity | Child | Histocompatibility | Sequence Deletion - genetics | Gene mutations | Anemia | Immunotherapy | Thyroid diseases | Resveratrol | Stem cells | Genetic aspects | Transplantation | Hematopoietic stem cells | Index Medicus | Clinical Medicine | Hematologi | Medical and Health Sciences | Hematology | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 6, pp. 1638 - 1641.e5
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 07/2018, Volume 142, Issue 1, pp. 317 - 321.e8
Natural killer (NK)-cell cytotoxicity was defective (Fig 1, D and G). [...]NK- and T-cell exocytosis was impaired (Fig 1, E and F, H and I), with IL-2... 
Cytotoxicity | Gene expression | Histiocytosis | Patients | Pigmentation | Fever | Immunology | Lymphocytes | Stem cells | Lymphomas | Mutation | Lymphocytosis | Age
Journal Article
Journal Article
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 12/2015, Volume 62, Issue 12, pp. 2094 - 2100
Journal Article