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by Gusarova, Viktoria and O’Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
PLoS genetics, ISSN 1553-7404, 2012, Volume 8, Issue 8, p. e1002793
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2017, Volume 377, Issue 3, pp. 211 - 221
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2018, Volume 378, Issue 12, pp. 1096 - 1106
Journal Article
Nature genetics, ISSN 1546-1718, 2018, Volume 50, Issue 9, pp. 1234 - 1239
Journal Article
Nature genetics, ISSN 1546-1718, 2018, Volume 50, Issue 11, pp. 1514 - 1523
...Author(s): Derek Klarin [sup.1] [sup.2] [sup.3], Scott M. Damrauer [sup.4] [sup.5], Kelly Cho [sup.6], Yan V. Sun [sup.7], Tanya M. Teslovich [sup.8... 
Cardiovascular Diseases - ethnology | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Hispanic Americans - statistics & numerical data | Male | Cardiovascular Diseases - genetics | Diabetes Mellitus, Type 2 - ethnology | Ethnic Groups - genetics | Lipids - blood | Cardiovascular Diseases - blood | Female | Lipid Metabolism - genetics | African Continental Ancestry Group - genetics | Ethnic Groups - statistics & numerical data | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Hispanic Americans - genetics | European Continental Ancestry Group - statistics & numerical data | Genotype | African Continental Ancestry Group - statistics & numerical data | Diabetes Mellitus, Type 2 - blood | Aged | Polymorphism, Single Nucleotide | Veterans - statistics & numerical data | Wellness programs | Usage | Genetic variation | Analysis | Military personnel | Genetic aspects | Research | Blood lipids | Health aspects | Laboratories | Veterans | Angioplasty | Lipids | Cardiovascular disease | Genomes | Electronic medical records | Blood | Consortia | Aorta | Genetics | Diabetes mellitus (non-insulin dependent) | Heart diseases | Phenotypes | Research & development--R&D | Diabetes mellitus | Data processing | Principal components analysis | Triglycerides | Genetic diversity | Cholesterol | Abdomen | Meta-analysis | Studies | Quality control | Gene loci | Diabetes | Mutation | Electronic health records | Hispanics | coronary artery disease | population genetics | genome-wide association studies
Journal Article
by Flannick, Jason and Thorleifsson, Gudmar and Beer, Nicola L and Jacobs, Suzanne B R and Grarup, Niels and Burtt, Noël P and Mahajan, Anubha and Fuchsberger, Christian and Atzmon, Gil and Benediktsson, Rafn and Blangero, John and Bowden, Don W and Brandslund, Ivan and Brosnan, Julia and Burslem, Frank and Chambers, John and Cho, Yoon Shin and Christensen, Cramer and Douglas, Desirée A and Duggirala, Ravindranath and Dymek, Zachary and Farjoun, Yossi and Fennell, Timothy and Fontanillas, Pierre and Forsén, Tom and Gabriel, Stacey and Glaser, Benjamin and Gudbjartsson, Daniel F and Hanis, Craig and Hansen, Torben and Hreidarsson, Astradur B and Hveem, Kristian and Ingelsson, Erik and Isomaa, Bo and Johansson, Stefan and Jørgensen, Torben and Jørgensen, Marit Eika and Kathiresan, Sekar and Kong, Augustine and Kooner, Jaspal and Kravic, Jasmina and Laakso, Markku and Lee, Jong-Young and Lind, Lars and Lindgren, Cecilia M and Linneberg, Allan and Masson, Gisli and Meitinger, Thomas and Mohlke, Karen L and Molven, Anders and Morris, Andrew P and Potluri, Shobha and Rauramaa, Rainer and Ribel-Madsen, Rasmus and Richard, Ann-Marie and Rolph, Tim and Salomaa, Veikko and Segrè, Ayellet V and Skärstrand, Hanna and Steinthorsdottir, Valgerdur and Stringham, Heather M and Sulem, Patrick and Tai, E Shyong and Teo, Yik Ying and Teslovich, Tanya and Thorsteinsdottir, Unnur and Trimmer, Jeff K and Tuomi, Tiinamaija and Tuomilehto, Jaakko and Vaziri-Sani, Fariba and Voight, Benjamin F and Wilson, James G and Boehnke, Michael and McCarthy, Mark I and Njølstad, Pål R and Pedersen, Oluf and Groop, Leif and Cox, David R and Stefansson, Kari and Altshuler, David and Go-T2D Consortium and T2D-GENES Consortium and T2D-Genes Consortium
Nature genetics, ISSN 1546-1718, 2014, Volume 46, Issue 4, pp. 357 - 363
Journal Article