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by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Index Medicus | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
by Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and Trzaskowski, MacIej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Air, Tracy M and Andlauer, Till M. F and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan F. T and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas R. H and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan I. R and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Crowley, Cheynna A and Dashti, Hassan S and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and DIrek, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Eriksson, Nicholas and Escott-Price, Valentina and Kiadeh, Farnush Hassan Farhadi and Finucane, Hilary K and Forstner, Andreas J and Frank, Josef and Gaspar, Héléna A and Gill, Michael and Giusti-Rodríguez, Paola and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hannon, Eilis and Hansen, Christine Søholm and Hansen, Thomas F and Herms, Stefan and Hickie, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Hu, Ming and Hyde, Craig L and Ising, Marcus and Jansen, Rick and Jin, Fulai and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Lane, Jacqueline M and Li, Yihan and Li, Yun and Lind, Penelope A and Liu, Xiaoxiao and Lu, Leina and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Robert M and Maier, Wolfgang and Marchini, Jonathan and Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and Medland, Sarah E and Mehta, DIvya and Middeldorp, Christel M and Mihailov, Evelin and Milaneschi, Yuri and Milani, Lili and Mill, Jonathan and Mondimore, Francis M and Montgomery, Grant W and Mostafavi, Sara and Mullins, Niamh and Nauck, Matthias and Ng, Bernard and ... and Major Depressive Disorder Working and EQTLGEN and eQTLGen and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and 23andMe and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 668 - 681
Journal Article
Frontiers in cardiovascular medicine, ISSN 2297-055X, 2018, Volume 5, pp. 51 - 51
Mendelian randomization (MR) is a framework for assessing causal inference using cross-sectional data in combination with genetic information. This paper... 
Genetics | Usage | Statistical methods | Research | GWAS | causal inference | mendelian randomization | statistical methods | bias
Journal Article
by Medici, Marco and Porcu, Eleonora and Pistis, Giorgio and Teumer, Alexander and Brown, Stephen and Jensen, Richard and Rawal, R and Roef, Greet and Plantinga, Theo S and Vermeulen, Sita and Lahti, Jari and Simmonds, Mark and Husemoen, Lise Lotte and Freathy, Rachel and Shields, Beverley and Pietzner, Diana and Nagy, Rebecca and Broer, Linda and Chaker, Layal and Korevaar, Tim and Plia, Maria Grazia and Sala, Cinzia and Völker, Uwe and Richards, Brent and Sweep, Fred and Gieger, Christian and Corre, Tanguy and Kajantie, Eero and Thuesen, Leif and Taes, Youri and Visser, Wil Edward and Hattersley, Anew and Kratzsch, Jürgen and Hamilton, Amy and Li, Wei and Homuth, Georg and Lobina, Monia and Mariotti, Stefano and Soranzo, Nicole and Cocca, Massimiliano and Nauck, Matthias and Spielhagen, Christin and Ross, Alec and Arnold, Alice and Bunt, Martijn and Liyanarachchi, Sandya and Heier, Margit and Grabe, Hans Jörgen and Masciullo, Corrado and Galesloot, Tessel and Lim, Ee Mun and Reischl, Gunilla and Leedman, Peter and Lai, Sana and Delitala, Alessano and Bremner, Alexana and Philips, David I and Beilby, John and Mulas, Antonella and Vocale, Matteo and Abecasis, Gonçalo and Forsen, Tom and James, Alan and Widen, Elisabeth and Hui, Jennie and Prokisch, Holger and Rietzschel, Ernst and Palotie, Aarno and Feddema, Wouter and Fletcher, Stephen and Schramm, Katharina and Rotter, Jerome and Kluttig, Alexander and Radke, Dörte and Traglia, Michela and Surdulescu, Gabriela and He, Hao and Franklyn, Jayne and Tiller, Daniel and Vaidya, Bijay and Meyer, Thorsten and Jorgensen, Torben and Hagen, Knut and O'Leary, Peter and Wichmann, Eric and Hermus, Ad and Psaty, Bruce and Ittermann, Till and Hofman, Albert and Bosi, Emanuele and Schlessinger, David and Wallaschofski, Henri and Pirastu, Nicola and Aulchenko, Yurii and de la Chapelle, Albert and Netea-Maier, Romana and Gough, Julie and Meyer zu Schwabedissen, Henriette and Frayling, Timothy and Kaufman, Jean-Marc and ...
PL o S Genetics (Online), ISSN 1553-7390, 02/2014, Volume 10, Issue 2, pp. e1004123 - e1004123
Journal Article
by Ripke, S and Wray, N.R and Lewis, C.M and Hamilton, S.P and Weissman, M.M and Breen, G and Byrne, E.M and Blackwood, D.H and Boomsma, D.I and Cichon, S and Heath, A.C and Holsboer, F and Lucae, S and Madden, P.A and Martin, N.G and McGuffin, P and Muglia, P and Noethen, M.M and Penninx, B.W.J.H and Pergadia, M.L and Potash, J.B and Rietschel, M and Lin, D and Müller-Myhsok, B and Shi, J and Steinberg, S and Grabe, H.J and Lichtenstein, P and Magnusson, P and Perlis, R.H and Preisig, M and Smoller, J.W and Stefansson, K and Uher, R and Kutalik, Z and Tansey, K.E and Teumer, A and Viktorin, A and Barnes, M.R and Bettecken, T and Binder, E.B and Breuer, R and Castro, V.M and Churchill, S.E and Coryell, W.H and Craddock, N and Craig, I.W and Czamara, D and de Geus, E.J.C and Degenhardt, F and Farmer, A.E and Fava, M and Frank, J and Gainer, V.S and Gallagher, P.J and Gordon, S.D and Goryachev, S and Gross, M and Guipponi, M and Henders, A.K and Herms, S and Hickie, I.B and Hoefels, S and Hoogendijk, W.J.G and Hottenga, J.J and Iosifescu, D.V and Ising, M and Jones, I and Jones, L and Jung-Ying, T and Knowles, J.A and Kohane, I.S and Kohli, M.A and Korszun, A and Landen, M and Lawson, W.B and Lewis, G and MacIntyre, D.J and Maier, W and Mattheisen, M and McGrath, P.J and McIntosh, A and McLean, A and Middeldorp, C.M and Middleton, L and Montgomery, G.M and Murphy, S.N and Nauck, M and Nolen, W.A and Nyholt and O'Donovan, M and Oskarsson, H and Pedersen, N and Scheftner, W.A and Schulz, A and Schulze, T.G and Shyn, S.I and Sigurdsson, E and Slager, S.L and Smit, J.H and ... and Psychiat GWAS Consortium and Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
Molecular Psychiatry, ISSN 1359-4184, 2013, Volume 18, Issue 4, pp. 497 - 511
Journal Article