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Nature Methods, ISSN 1548-7091, 01/2013, Volume 10, Issue 1, pp. 43 - 44
  A fully automated pipeline that systematically models three-dimensional (3D) structural details of protein interactions will allow researchers to interpret... 
BIOCHEMICAL RESEARCH METHODS | Multiprotein Complexes - chemistry | Animals | Proteins - metabolism | Models, Biological | Humans | Proteins - chemistry | Protein Interaction Mapping | Proteins | Cellular biology | Molecular biology
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1851, pp. 1 - 17
The function of a protein is largely determined by its three-dimensional structure and its interactions with other proteins. Changes to a protein's amino acid... 
Mutations | Protein engineering | Protein stability | Bioinformatics | Structural biology | Computational biology | Proteins - genetics | Thermodynamics | Computational Biology - methods | Proteins - metabolism | Protein Engineering | Protein Binding | Protein Stability | Mutation - genetics | Protein Folding | Index Medicus
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 4119 - 11
USP37 is a deubiquitinase (DUB) with roles in the regulation of DNA damage repair and the cohesion of sister chromatids during mitosis. USP37 contains a unique... 
DEUBIQUITINASE USP37 | INHIBITION | STRATEGY | ENZYMES | MULTIDISCIPLINARY SCIENCES | DISTINCT | POLYGLUTAMINE DISEASE PROTEIN | E3 LIGASES | BINDING | MODULATION | DISCOVERY | Ubiquitin | Potentiation | Sister chromatids | Mitosis | DNA damage | Chromatids | Catalysis | DNA repair | Binding sites
Journal Article
Journal Article
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 5/2011, Volume 25, Issue 5, pp. 477 - 489
Journal Article
BMC bioinformatics, 04/2016, Volume 17, p. 150
The identification of structured units in a protein sequence is an important first step for most biochemical studies. Importantly for this study, the... 
Protein Structure, Tertiary | Amino Acid Sequence | User-Computer Interface | Area Under Curve | Antibodies - chemistry | Humans | Peptide Library | Proteins - immunology | Databases, Protein | Antibodies - immunology | ROC Curve | Internet | Proteins - chemistry
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2016, Volume 291, Issue 34, pp. 17941 - 17952
Journal Article
Bioinformatics, ISSN 1367-4803, 05/2016, Volume 32, Issue 10, pp. 1589 - 1591
A Summary: ELASPIC is a novel ensemble machine-learning approach that predicts the effects of mutations on protein folding and protein-protein interactions.... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Humans | Protein Binding | Proteome | Software | Mutation | Protein Stability | Protein Folding | Index Medicus | Proteins | Mutations | Databases | Homology | Organisms | Mathematical models | Online | Bioinformatics
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 03/2019, Volume 431, Issue 6, pp. 1160 - 1171
We applied a yeast-two-hybrid (Y2H) analysis to screen for ubiquitin variant (UbV) inhibitors of a human deubiquitinase (DUB), ubiquitin-specific protease 2... 
Mdm2 | yeast two-hybrid | ubiquitin | ubiquitin variants | Ubiquitin Proteasome System | ANTIBODIES | DUBS | STRATEGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PEPTIDE APTAMERS | USP2A | ENZYMES | RESISTANCE | TARGETS | SELECTION | REVEALS | Ubiquitin | Molecular genetics | Proteases | Analysis | Tryptophan | Fluorescence | Cells
Journal Article