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Nature Genetics, ISSN 1061-4036, 12/2014, Volume 47, Issue 1, pp. 31 - 38
Cushing's disease is caused by corticotroph adenomas of the pituitary. To explore the molecular mechanisms of endocrine autonomy in these tumors, we performed... 
UBPY | ENDOSOMES | DOMAIN | PROTEIN | EPIDERMAL-GROWTH-FACTOR | GENETICS & HEREDITY | UBIQUITYLATION | DEGRADATION | RECEPTOR DOWN-REGULATION | ENDOCYTIC TRAFFICKING | PITUITARY-ADENOMAS | Adenoma - genetics | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Cercopithecus aethiops | Endosomal Sorting Complexes Required for Transport - genetics | Molecular Sequence Data | Pituitary Neoplasms - complications | ACTH-Secreting Pituitary Adenoma - complications | Pituitary ACTH Hypersecretion - genetics | ACTH-Secreting Pituitary Adenoma - genetics | Receptor, Epidermal Growth Factor - metabolism | Pituitary Neoplasms - secretion | Neoplasm Proteins - genetics | Pro-Opiomelanocortin - genetics | Amino Acid Sequence | ACTH-Secreting Pituitary Adenoma - metabolism | Pituitary Neoplasms - genetics | Ubiquitin Thiolesterase - physiology | Pituitary Neoplasms - metabolism | Ubiquitin Thiolesterase - genetics | 14-3-3 Proteins - metabolism | Adrenocorticotropic Hormone - secretion | Sequence Homology, Amino Acid | Exome - genetics | Sequence Alignment | Animals | Endopeptidases - genetics | ACTH-Secreting Pituitary Adenoma - secretion | Pro-Opiomelanocortin - biosynthesis | Mutation | COS Cells | Endosomal Sorting Complexes Required for Transport - physiology | Endopeptidases - physiology | Gene mutations | Cushing syndrome | Physiological aspects | Genetic aspects | Research | Ubiquitin-proteasome system | Health aspects | Risk factors | Pituitary gland | Kinases | Rodents | Genes | Tumors | Index Medicus
Journal Article
The Journal of clinical endocrinology and metabolism, 12/2018
The most frequent cause of endogenous hypercortisolism is Cushing disease (CD), a devastating condition associated with severe comorbidities and high... 
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2019, Volume 104, Issue 3, pp. 925 - 933
Context: The most frequent cause of endogenous hypercortisolism is Cushing disease (CD), a devastating condition associated with severe comorbidities and high... 
NELSONS-SYNDROME | ACTH-SECRETION | BASE-LINE | RETINOIC ACID | CYCLIN-E | BILATERAL ADRENALECTOMY | ENDOCRINOLOGY & METABOLISM | ADRENOCORTICOTROPIN SECRETION | PPAR-GAMMA | TRANSSPHENOIDAL SURGERY | PITUITARY CARCINOMA
Journal Article
Annals of Endocrinology (Annales D'Endocrinologie, English Edition), ISSN 0003-4266, 2012, Volume 73, Issue 2, pp. 71 - 72
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1725 - 12
Journal Article
Annales d'Endocrinologie, ISSN 0003-4266, 04/2012, Volume 73, Issue 2, pp. 71 - 72
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 10/2011, Volume 165, Issue 4, pp. 509 - 515
Journal Article
Clinical Endocrinology, ISSN 0300-0664, 10/2018, Volume 89, Issue 4, pp. 454 - 458
ObjectiveAlmost half of the cases of Cushing's disease (CD) tumours carry recurrent activating somatic mutations in the ubiquitin-specific protease eight gene... 
pituitary | recurrence | corticotroph tumour | USP | Cushing's disease | remission | adrenocorticotropic hormone | USP8 | MORTALITY | ENDOCRINOLOGY & METABOLISM | ADENOMAS | Ubiquitin | Medical research | Relapse | Proteases | Medicine, Experimental | ACTH | Genetic aspects | Tumors | Diseases | Nervous system diseases | Adrenocorticotropic hormone | Pituitary | Surgery | Remission | Mutation | Hydrocortisone
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 09/2009, Volume 16, Issue 3, pp. 1029 - 1043
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 7/2013, Volume 126, Issue 1, pp. 137 - 150
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 01/2018, Volume 178, Issue 1, pp. 57 - 63
Objective Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene are frequent in corticotroph tumors causing Cushing’s disease (CD). Corticotroph... 
Ubiquitin | Nervous system diseases | Ubiquitin-specific proteinase | Visual field | Adenoma | Adrenalectomy | Body mass index | Adrenocorticotropic hormone | Pituitary | Surgery | Mutation | Hyperpigmentation | Tumors
Journal Article
Journal Article
Endocrinology, diabetes & metabolism case reports, ISSN 2052-0573, 2018, Volume 2018, Issue 1, pp. 1 - 4
Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem hereditary cutaneous condition, characterized by multiple hamartomas. In rare cases,... 
Journal Article
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 07/2015, Volume 100, Issue 7, pp. E997 - E1004
Journal Article