Nature, ISSN 0028-0836, 09/2009, Volume 461, Issue 7263, pp. 486 - 487
For this purpose, studies at the level of the organism are indispensable, as they allow us to trace effects in different organs. [...] Owusu-Ansah and...
Antioxidants | Reactive oxygen species | Control | Immune response | Hematopoiesis | Physiological aspects | Research | Health aspects | Vertebrates | Kinases | Developmental biology | Rodents | Cells
Antioxidants | Reactive oxygen species | Control | Immune response | Hematopoiesis | Physiological aspects | Research | Health aspects | Vertebrates | Kinases | Developmental biology | Rodents | Cells
Journal Article
Journal of Innate Immunity, ISSN 1662-811X, 12/2011, Volume 4, Issue 1, pp. 117 - 118
Journal Article
Frontiers in Plant Science, ISSN 1664-462X, 07/2014, Volume 5, p. 342
Insects and mammals share an ancient innate immune system comprising both humoral and cellular responses. The insect immune system consists of the fat body,...
Nematodes | Innate immunity | Tumor | Coagulation | Danger | Hemocytes | WOUND CLOSURE | ACTIVATION | DROSOPHILA-MELANOGASTER | danger | coagulation | hemocytes | nematodes | PLANT SCIENCES | WAX-MOTH | innate immunity | ONCOGENIC RAS | tumor | HOST-DEFENSE | SMALL GTPASES | BLOOD-CELLS | RNAI SCREEN | molekylärbiologi | Biological Sciences | Naturvetenskap | Molecular Biology | Biologiska vetenskaper | Natural Sciences
Nematodes | Innate immunity | Tumor | Coagulation | Danger | Hemocytes | WOUND CLOSURE | ACTIVATION | DROSOPHILA-MELANOGASTER | danger | coagulation | hemocytes | nematodes | PLANT SCIENCES | WAX-MOTH | innate immunity | ONCOGENIC RAS | tumor | HOST-DEFENSE | SMALL GTPASES | BLOOD-CELLS | RNAI SCREEN | molekylärbiologi | Biological Sciences | Naturvetenskap | Molecular Biology | Biologiska vetenskaper | Natural Sciences
Journal Article
Nature, ISSN 0028-0836, 09/2009, Volume 461, Issue 7263, pp. 486 - 487
HEMATOPOIETIC STEM-CELL | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | Reactive Oxygen Species - metabolism | Signal Transduction | Humans | Larva - metabolism | Drosophila melanogaster - cytology | Blood Cells - metabolism | Hematopoietic Stem Cells - metabolism | Immune System - cytology | Larva - cytology | Drosophila melanogaster - metabolism | Animals | Blood Cells - cytology | Hematopoiesis | Hematopoietic Stem Cells - cytology | Drosophila melanogaster - growth & development | Cell Differentiation
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e113051
Some organisms can adapt to seasonal and other environmental challenges by entering a state of dormancy, diapause. Thus, insects exposed to decreased...
CLIMATIC ADAPTATION | CAENORHABDITIS-ELEGANS | MULTIDISCIPLINARY SCIENCES | INSULIN-LIKE PEPTIDE | GENE-EXPRESSION | EXTENDS LIFE-SPAN | INSECT DIAPAUSE | OVERWINTERING DIAPAUSE | CELL-PROLIFERATION | MOSQUITO CULEX-PIPIENS | NUTRIENT AVAILABILITY | Animals | Time Factors | Diapause, Insect - physiology | Female | Insulins - metabolism | Ovary - physiology | Signal Transduction - physiology | Drosophila Proteins - metabolism | Drosophila melanogaster | Regulators | Senescence | Peptides | Glucagon | Zoology | Diapause | Genes | Gene regulation | Homeostasis | Lipids | Innate immunity | Infections | Kinases | Immunity | Experiments | Dormancy | Intestine | Aging | Cecropin | Physiology | Lipid metabolism | Immune system | Carbohydrates | Immune response | Drosophila | Carbohydrate metabolism | Metabolism | Gene expression | Epithelium | Insulin | Signaling | Drosomycin | Insects | Life span | Food intake | Stem cells | Environmental monitoring | Flies | Females | Endocrinology | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
CLIMATIC ADAPTATION | CAENORHABDITIS-ELEGANS | MULTIDISCIPLINARY SCIENCES | INSULIN-LIKE PEPTIDE | GENE-EXPRESSION | EXTENDS LIFE-SPAN | INSECT DIAPAUSE | OVERWINTERING DIAPAUSE | CELL-PROLIFERATION | MOSQUITO CULEX-PIPIENS | NUTRIENT AVAILABILITY | Animals | Time Factors | Diapause, Insect - physiology | Female | Insulins - metabolism | Ovary - physiology | Signal Transduction - physiology | Drosophila Proteins - metabolism | Drosophila melanogaster | Regulators | Senescence | Peptides | Glucagon | Zoology | Diapause | Genes | Gene regulation | Homeostasis | Lipids | Innate immunity | Infections | Kinases | Immunity | Experiments | Dormancy | Intestine | Aging | Cecropin | Physiology | Lipid metabolism | Immune system | Carbohydrates | Immune response | Drosophila | Carbohydrate metabolism | Metabolism | Gene expression | Epithelium | Insulin | Signaling | Drosomycin | Insects | Life span | Food intake | Stem cells | Environmental monitoring | Flies | Females | Endocrinology | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0136593
Apart from their role in cellular immunity via phagocytosis and encapsulation, Drosophila hemocytes release soluble factors such as antimicrobial peptides, and...
CELLS | PROTEIN | GENE | MULTIDISCIPLINARY SCIENCES | GROWTH | INCREASES | SIGNALS | INFECTION | EXPRESSION | REVEALS | Immune response | Blood cells | Drosophila | Physiological aspects | Genetic aspects | Research | Apoptosis | Larvae | Drinking water | Neurosciences | Peptides | Plasmatocytes | Infections | Lethality | Immune status | Phylogeny | Immunity | Blood | Immunity (cell-mediated) | Proteins | Microbiota | Developmental stages | Arginine | Antimicrobial peptides | Immune system | Crystal defects | Immunoglobulins | Cytokines | Food sources | Hemolymph | Inflammation | Entomopathogenic nematodes | Nodules | Wounding | Antibiotics | Insects | Nitric oxide | Nematodes | Phagocytosis | Hemocytes
CELLS | PROTEIN | GENE | MULTIDISCIPLINARY SCIENCES | GROWTH | INCREASES | SIGNALS | INFECTION | EXPRESSION | REVEALS | Immune response | Blood cells | Drosophila | Physiological aspects | Genetic aspects | Research | Apoptosis | Larvae | Drinking water | Neurosciences | Peptides | Plasmatocytes | Infections | Lethality | Immune status | Phylogeny | Immunity | Blood | Immunity (cell-mediated) | Proteins | Microbiota | Developmental stages | Arginine | Antimicrobial peptides | Immune system | Crystal defects | Immunoglobulins | Cytokines | Food sources | Hemolymph | Inflammation | Entomopathogenic nematodes | Nodules | Wounding | Antibiotics | Insects | Nitric oxide | Nematodes | Phagocytosis | Hemocytes
Journal Article
PLoS Pathogens, ISSN 1553-7366, 02/2010, Volume 6, Issue 2, p. e1000763
Clotting systems are required in almost all animals to prevent loss of body fluids after injury. Here, we show that despite the risks associated with its...
DEFENSE | BACTERIA | PROTEIN | DROSOPHILA-MELANOGASTER | MICROBIOLOGY | SEPSIS | HEMOLYMPH | FACTOR-V-LEIDEN | VIROLOGY | GALLERIA-MELLONELLA | COAGULATION | INFECTION | PARASITOLOGY | Sepsis - immunology | Hemolymph - immunology | Humans | Drosophila Proteins - immunology | Immunity, Innate | Transglutaminases - immunology | Animals | Hemolymph - microbiology | Blood Coagulation - immunology | Bacterial Infections - immunology | Drosophila - immunology | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Microscopy, Fluorescence | Physiological aspects | Transglutaminases | Immune response | Research | Health aspects | Drosophila | molekylärbiologi | Biological Sciences | Naturvetenskap | Natural Sciences | Molecular Biology | Biologiska vetenskaper | Enzymes | E coli | Mortality | Nematodes | Bacteria | Sepsis | Circulatory system | Experiments | Immune system | Blood clots
DEFENSE | BACTERIA | PROTEIN | DROSOPHILA-MELANOGASTER | MICROBIOLOGY | SEPSIS | HEMOLYMPH | FACTOR-V-LEIDEN | VIROLOGY | GALLERIA-MELLONELLA | COAGULATION | INFECTION | PARASITOLOGY | Sepsis - immunology | Hemolymph - immunology | Humans | Drosophila Proteins - immunology | Immunity, Innate | Transglutaminases - immunology | Animals | Hemolymph - microbiology | Blood Coagulation - immunology | Bacterial Infections - immunology | Drosophila - immunology | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Microscopy, Fluorescence | Physiological aspects | Transglutaminases | Immune response | Research | Health aspects | Drosophila | molekylärbiologi | Biological Sciences | Naturvetenskap | Natural Sciences | Molecular Biology | Biologiska vetenskaper | Enzymes | E coli | Mortality | Nematodes | Bacteria | Sepsis | Circulatory system | Experiments | Immune system | Blood clots
Journal Article
Annual Review of Entomology, ISSN 0066-4170, 01/2010, Volume 55, Issue 1, pp. 485 - 504
The recognition and inactivation of toxins and pathogens are mediated by a combination of cell-free and cellular mechanisms. A number of soluble and...
Phenoloxidase activating cascade | Innate immune recognition | Coagulation | Lipophorin particles | Hemolin | Hemomucin | Peroxinectin | APOLIPOPHORIN-III | IMMUNOGLOBULIN SUPERFAMILY | DROSOPHILA-MELANOGASTER | CRYSTAL-STRUCTURE | hemolin | BINDING-PROTEIN | hemomucin | CELL-ADHESION | coagulation | ENTOMOLOGY | peroxinectin | lipophorin particles | HELIX-POMATIA LECTIN | GALLERIA-MELLONELLA | phenoloxidase activating cascade | innate immune recognition | HIGH-DENSITY-LIPOPROTEINS | INNATE IMMUNITY | Lipids - immunology | Arthropods - immunology | Animals | Cell Adhesion Molecules - immunology | Insect Proteins - immunology | Immunity, Innate | Immune recognition | Research | Entomology | Health aspects | Arthropoda | Biologi med inriktning mot jämförande fysiologi | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Biology with specialization in Comparative Physiology | Biology | Biologi | Natural Sciences
Phenoloxidase activating cascade | Innate immune recognition | Coagulation | Lipophorin particles | Hemolin | Hemomucin | Peroxinectin | APOLIPOPHORIN-III | IMMUNOGLOBULIN SUPERFAMILY | DROSOPHILA-MELANOGASTER | CRYSTAL-STRUCTURE | hemolin | BINDING-PROTEIN | hemomucin | CELL-ADHESION | coagulation | ENTOMOLOGY | peroxinectin | lipophorin particles | HELIX-POMATIA LECTIN | GALLERIA-MELLONELLA | phenoloxidase activating cascade | innate immune recognition | HIGH-DENSITY-LIPOPROTEINS | INNATE IMMUNITY | Lipids - immunology | Arthropods - immunology | Animals | Cell Adhesion Molecules - immunology | Insect Proteins - immunology | Immunity, Innate | Immune recognition | Research | Entomology | Health aspects | Arthropoda | Biologi med inriktning mot jämförande fysiologi | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Biology with specialization in Comparative Physiology | Biology | Biologi | Natural Sciences
Journal Article
Trends in Immunology, ISSN 1471-4906, 2004, Volume 25, Issue 6, pp. 289 - 294
Arthropods have open circulatory systems and must seal wounds and keep bacteria from entering the hemocoel using efficient clotting systems. Enzymes that...
FRESH-WATER CRAYFISH | LIMULUS BLOOD-CLOT | HORSESHOE-CRAB | DROSOPHILA-MELANOGASTER | GENOME-WIDE ANALYSIS | INNATE IMMUNE-SYSTEM | ANOPHELES-GAMBIAE | SERINE-PROTEASE | IMMUNOLOGY | VON-WILLEBRAND-FACTOR | MASQUERADE-LIKE PROTEIN | Arthropods - physiology | Animals | Hemolymph - immunology | Insecta - immunology | Models, Biological | Drosophila - immunology | Arthropods - immunology | Insecta - physiology | Hemolymph - physiology | Wound Healing | Drosophila - physiology | Biological Sciences | Immunology | Naturvetenskap | Immunologi | Natural Sciences | Biologiska vetenskaper
FRESH-WATER CRAYFISH | LIMULUS BLOOD-CLOT | HORSESHOE-CRAB | DROSOPHILA-MELANOGASTER | GENOME-WIDE ANALYSIS | INNATE IMMUNE-SYSTEM | ANOPHELES-GAMBIAE | SERINE-PROTEASE | IMMUNOLOGY | VON-WILLEBRAND-FACTOR | MASQUERADE-LIKE PROTEIN | Arthropods - physiology | Animals | Hemolymph - immunology | Insecta - immunology | Models, Biological | Drosophila - immunology | Arthropods - immunology | Insecta - physiology | Hemolymph - physiology | Wound Healing | Drosophila - physiology | Biological Sciences | Immunology | Naturvetenskap | Immunologi | Natural Sciences | Biologiska vetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e108795
The immune defence of an organism is evolving continuously, causing counteradaptations in interacting species, which in turn affect other ecological and...
DEFENSE | PHENOLOXIDASE | PHAGOCYTOSIS | DROSOPHILA-MELANOGASTER | HEMOCYTES | MULTIDISCIPLINARY SCIENCES | LARVAE | HOST | COAGULATION | CHRYSOMELIDAE | PLASTICITY | Biological Evolution | Animals | Coleoptera - parasitology | Immune System - physiology | Larva - immunology | Hemolymph - immunology | Wasps - physiology | Host-Parasite Interactions | Coleoptera - immunology | Encapsulation | Parasitoids | Biological evolution | Parasites | Immunity | Experiments | Eggs | Ecological effects | Phagocytes | Immunology | Granulocytes | Ecological monitoring | Plant sciences | Dissection | Species | Immune system | Pathogens | Immune response | Hemolymph | Studies | Insects | Comparative studies | Parasitism | Leukocytes (granulocytic) | Hemocytes | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper | växtekologi | Plant Ecology
DEFENSE | PHENOLOXIDASE | PHAGOCYTOSIS | DROSOPHILA-MELANOGASTER | HEMOCYTES | MULTIDISCIPLINARY SCIENCES | LARVAE | HOST | COAGULATION | CHRYSOMELIDAE | PLASTICITY | Biological Evolution | Animals | Coleoptera - parasitology | Immune System - physiology | Larva - immunology | Hemolymph - immunology | Wasps - physiology | Host-Parasite Interactions | Coleoptera - immunology | Encapsulation | Parasitoids | Biological evolution | Parasites | Immunity | Experiments | Eggs | Ecological effects | Phagocytes | Immunology | Granulocytes | Ecological monitoring | Plant sciences | Dissection | Species | Immune system | Pathogens | Immune response | Hemolymph | Studies | Insects | Comparative studies | Parasitism | Leukocytes (granulocytic) | Hemocytes | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper | växtekologi | Plant Ecology
Journal Article
European Journal of Trauma and Emergency Surgery, ISSN 1863-9933, 4/2019, Volume 45, Issue 2, pp. 207 - 212
Periprosthetic joint infections (PJI) after hemiarthroplasty for geriatric femoral neck fractures are a devastating complication that results in serious...
CRP | Obesity | Emergency Medicine | Glucocorticoids | Intensive / Critical Care Medicine | Femoral neck fracture | Hip fracture | Surgical Orthopedics | Periprosthetic joint infection | Medicine & Public Health | Sports Medicine | Traumatic Surgery | Surgery | Surgical site infection | Hemiarthroplasty | JOINT INFECTION | TOTAL HIP-ARTHROPLASTY | EMERGENCY MEDICINE | BODY-MASS | COMPLICATIONS
CRP | Obesity | Emergency Medicine | Glucocorticoids | Intensive / Critical Care Medicine | Femoral neck fracture | Hip fracture | Surgical Orthopedics | Periprosthetic joint infection | Medicine & Public Health | Sports Medicine | Traumatic Surgery | Surgery | Surgical site infection | Hemiarthroplasty | JOINT INFECTION | TOTAL HIP-ARTHROPLASTY | EMERGENCY MEDICINE | BODY-MASS | COMPLICATIONS
Journal Article
Virulence, ISSN 2150-5594, 11/2017, Volume 8, Issue 8, pp. 1468 - 1470
Journal Article
PLoS ONE, 08/2015, Volume 10, Issue 8
Journal Article
Journal of Innate Immunity, ISSN 1662-811X, 12/2010, Volume 3, Issue 1, pp. 34 - 40
Bacterial infections represent a serious health care problem, and all multicellular organisms have developed defense mechanisms to eliminate pathogens that...
Review | Vertebrates | Host defense | Immune response | Invertebrates | Coagulation | ACTIVATION | RECOGNITION | DROSOPHILA-MELANOGASTER | TRANSGLUTAMINASE | IMMUNOLOGY | INACTIVATION | FACTOR-XIII | INSECT HEMOLYMPH | CLOTTING PROTEIN | LIPOPROTEINS | BLOOD | Mammals - genetics | Insecta - immunology | Vertebrates - genetics | Humans | Vertebrates - immunology | Immunity, Innate - genetics | Invertebrates - genetics | Blood Coagulation Factors - genetics | Blood Coagulation Factors - metabolism | Insecta - genetics | Biological Evolution | Immunity, Innate - immunology | Animals | Blood Coagulation - immunology | Mammals - immunology | Invertebrates - immunology | Blood Coagulation - genetics | Mice | Naturvetenskap | Natural Sciences
Review | Vertebrates | Host defense | Immune response | Invertebrates | Coagulation | ACTIVATION | RECOGNITION | DROSOPHILA-MELANOGASTER | TRANSGLUTAMINASE | IMMUNOLOGY | INACTIVATION | FACTOR-XIII | INSECT HEMOLYMPH | CLOTTING PROTEIN | LIPOPROTEINS | BLOOD | Mammals - genetics | Insecta - immunology | Vertebrates - genetics | Humans | Vertebrates - immunology | Immunity, Innate - genetics | Invertebrates - genetics | Blood Coagulation Factors - genetics | Blood Coagulation Factors - metabolism | Insecta - genetics | Biological Evolution | Immunity, Innate - immunology | Animals | Blood Coagulation - immunology | Mammals - immunology | Invertebrates - immunology | Blood Coagulation - genetics | Mice | Naturvetenskap | Natural Sciences
Journal Article
Journal of Innate Immunity, ISSN 1662-811X, 02/2014, Volume 6, Issue 2, pp. 192 - 204
Heterorhabditis bacteriophora is an entomopathogenic nematode (EPN) which infects its host by accessing the hemolymph where it releases endosymbiotic bacteria...
Research Article | Recognition molecule | Thioester-containing proteins | Hemocyte | Coagulation | Nematodes | Insect immunity | Basement membrane | IMMUNE-RESPONSE | ADULT FLIES | BACTERIA | IMMUNOLOGY | PGRP-LC | ARMIGERES-SUBALBATUS | GENE-EXPRESSION | HOST-DEFENSE | MELANOGASTER | WOUND REPAIR | RNAI SCREEN | Drosophila melanogaster - immunology | Membrane Glycoproteins - metabolism | Oligonucleotide Array Sequence Analysis | Hemocytes - immunology | Complement System Proteins - immunology | Transcriptome - immunology | Drosophila Proteins - immunology | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Complement System Proteins - metabolism | Host-Pathogen Interactions - immunology | Photorhabdus - physiology | Larva - immunology | RNA Interference | Rhabditoidea - physiology | Complement System Proteins - genetics | Larva - genetics | Genome, Insect | Membrane Glycoproteins - immunology | Extracellular Matrix Proteins - metabolism | Gene Ontology | Rhabditoidea - microbiology | Animals, Genetically Modified | Extracellular Matrix Proteins - genetics | Host-Parasite Interactions - immunology | Reverse Transcriptase Polymerase Chain Reaction | Hemocytes - metabolism | Photorhabdus - immunology | Membrane Glycoproteins - genetics | Microscopy, Confocal | Animals | Extracellular Matrix Proteins - immunology | Larva - parasitology | Drosophila melanogaster - parasitology | Rhabditoidea - immunology | Luminescent Proteins - genetics | Drosophila Proteins - genetics | Cluster Analysis | Luminescent Proteins - metabolism | Biological Sciences | Immunologi | Molecular Biology | molekylärbiologi | Immunology | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Research Article | Recognition molecule | Thioester-containing proteins | Hemocyte | Coagulation | Nematodes | Insect immunity | Basement membrane | IMMUNE-RESPONSE | ADULT FLIES | BACTERIA | IMMUNOLOGY | PGRP-LC | ARMIGERES-SUBALBATUS | GENE-EXPRESSION | HOST-DEFENSE | MELANOGASTER | WOUND REPAIR | RNAI SCREEN | Drosophila melanogaster - immunology | Membrane Glycoproteins - metabolism | Oligonucleotide Array Sequence Analysis | Hemocytes - immunology | Complement System Proteins - immunology | Transcriptome - immunology | Drosophila Proteins - immunology | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Complement System Proteins - metabolism | Host-Pathogen Interactions - immunology | Photorhabdus - physiology | Larva - immunology | RNA Interference | Rhabditoidea - physiology | Complement System Proteins - genetics | Larva - genetics | Genome, Insect | Membrane Glycoproteins - immunology | Extracellular Matrix Proteins - metabolism | Gene Ontology | Rhabditoidea - microbiology | Animals, Genetically Modified | Extracellular Matrix Proteins - genetics | Host-Parasite Interactions - immunology | Reverse Transcriptase Polymerase Chain Reaction | Hemocytes - metabolism | Photorhabdus - immunology | Membrane Glycoproteins - genetics | Microscopy, Confocal | Animals | Extracellular Matrix Proteins - immunology | Larva - parasitology | Drosophila melanogaster - parasitology | Rhabditoidea - immunology | Luminescent Proteins - genetics | Drosophila Proteins - genetics | Cluster Analysis | Luminescent Proteins - metabolism | Biological Sciences | Immunologi | Molecular Biology | molekylärbiologi | Immunology | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article