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Immunity, ISSN 1074-7613, 2008, Volume 29, Issue 6, pp. 958 - 970
Natural killer (NK) cells are innate lymphocytes with spontaneous antitumor activity, and they produce interferon-γ (IFN-γ) that primes immune responses.... 
CELLIMMUNO | NATURAL-KILLER-CELLS | LYMPHOID-TISSUES | ROR-GAMMA-T | NK CELLS | IN-VIVO | PROINFLAMMATORY IL-17(+) | HOST-DEFENSE | DIFFERENTIATION | IMMUNOLOGY | LAMINA PROPRIA | DEVELOPMENTAL PATHWAYS | Immunity, Mucosal - immunology | Intestines - metabolism | Interleukins - metabolism | Intestines - immunology | Enterobacteriaceae Infections - immunology | Signal Transduction - immunology | Interleukins - immunology | Receptors, Retinoic Acid - immunology | Killer Cells, Natural - immunology | Antigens, Ly - metabolism | Perforin - immunology | Natural Cytotoxicity Triggering Receptor 1 - immunology | Receptors, Thyroid Hormone - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 | Citrobacter rodentium - immunology | Enterobacteriaceae Infections - microbiology | Mice, Inbred C57BL | Receptors, Retinoic Acid - metabolism | Immunity, Innate | Mice, Knockout | Receptors, Thyroid Hormone - metabolism | Animals | Intestines - microbiology | Antigens, Ly - immunology | Natural Cytotoxicity Triggering Receptor 1 - metabolism | Mice | Perforin - metabolism | Killer Cells, Natural - metabolism | Infections | Lymphocytes | Rodents | Stem cells | Immune system | Index Medicus | Life Sciences | Human health and pathology | Microbiology and Parasitology | Hépatology and Gastroenterology | Immunology | Bacteriology
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3486 - 8
The CRISPR/Cas9 gene editing tool enables accessible and efficient modifications which (re)ignited molecular research in certain species. However, targeted... 
CRISPR | CAS9 | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | ONE-STEP GENERATION | Insertion | Animal models | Homologous recombination | Cloning | Deoxyribonucleic acid--DNA
Journal Article
EMBO reports, ISSN 1469-221X, 11/2018, Volume 19, Issue 11, pp. e46193 - n/a
The 1555 A to G substitution in mitochondrial 12S A‐site rRNA is associated with maternally transmitted deafness of variable penetrance in the absence of... 
protein synthesis | disease | aging | misreading | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-SYNTHESIS | MAMMALIAN MITOCHONDRIAL RIBOSOME | TRANSFER-RNA SYNTHETASES | CELL BIOLOGY | GENE-EXPRESSION DATA | HEARING-LOSS | AMINOGLYCOSIDE OTOTOXICITY | MEDIATED RECOMBINATION | MUTATION | MICE | DEAFNESS | Brain - cytology | Protein Biosynthesis | Methionine - metabolism | Ribosomal Proteins - genetics | Stress, Physiological - genetics | Humans | Ribosomes - metabolism | Mice, Transgenic | Mitochondria - metabolism | Mitochondrial Proteins - genetics | Electron Transport Complex IV - genetics | Electron Transport Complex IV - metabolism | Behavior, Animal | Hearing Disorders - genetics | Animals | Aging - genetics | Mitochondria - genetics | Ribosomes - genetics | HEK293 Cells | Escherichia coli Proteins - genetics | Cysteine - metabolism | Noise - adverse effects | RNA, Messenger | Adaptations | Misreading | rRNA 12S | Mitochondrial DNA | Proteins | Mitochondria | Alterations | Coding | Lymphocytes | Physiology | Anxiety | Deafness | Phenotypes | Translation | Methionine | Protein biosynthesis | Gene expression | Hearing loss | Hearing | Mutagenesis | Ribosomal proteins | Protein synthesis | Cochlea | Mice | Mutation | Index Medicus | Life Sciences | Molecular biology | Biochemistry, Molecular Biology | Protein Biosynthesis & Quality Control | Molecular Biology of Disease
Journal Article
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2010, Volume 597, pp. 189 - 209
With the lack of tools available to manipulate the rat genome, alternative technologies have been investigated to generate loss-of-function rat models by gene... 
Animals | RNA Interference | Animals, Genetically Modified - genetics | Rats | Mice | Models, Genetic | Genome | Genomics - methods | Gene Knockdown Techniques - methods | RNA, Antisense - genetics | Index Medicus
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 12/2004, Volume 578, Issue 1-2, pp. 116 - 120
Journal Article
FEBS Letters, ISSN 0014-5793, 2004, Volume 578, Issue 1, pp. 116 - 120
Two melatonin receptors (MT and MT ) have been cloned. A third melatonin binding site, , is known with remarkable and distinct pharmacological properties. We... 
Knock-out mice: Quinone reductase 1 | Dihydronicotinamide riboside:quinone oxidoreductase 2 | MT3 | Melatonin receptor | MCA-NAT | quinone reductase 1 | NQO2 | NRH | NRH:quinone oxidoreductase 2 | BNAH | acetyltryptamine | 5-methoxycarbonylamino | dihydronicotinamide riboside | QR1 | benzyldihydronicotinamide
Journal Article
Bulletin of the World Health Organization, ISSN 0042-9686, 12/2005, Volume 83, Issue 12, p. 935
Objective To evaluate, in a developing country, the effect of a short training programme for general healthcare workers on the management of common skin... 
Skin diseases | Care and treatment | Forecasts and trends | World health
Journal Article
Bulletin of the World Health Organization, ISSN 0042-9686, 12/2005, Volume 83, Issue 12, pp. 935 - 941
OBJECTIVE: To evaluate, in a developing country, the effect of a short training programme for general health care workers on the management of common skin... 
Health Policy & Services
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2001, Volume 44, Issue 3, pp. 468 - 471
Journal Article
FEBS Letters, ISSN 0014-5793, 1999, Volume 459, Issue 3, pp. 285 - 290
Protein kinases C (PKC) are serine/threonine kinase enzymes involved in the mechanism of cell survival. Their pseudosubstrate sequences are autoinhibitory... 
PKC isoform | Intracellular delivery | PKC pseudosubstrate lipopeptide | Apoptosis
Journal Article