Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (11) 11
index medicus (10) 10
hematology (8) 8
mice (8) 8
thrombosis (8) 8
mice, inbred c57bl (7) 7
peripheral vascular disease (7) 7
activation (6) 6
disease models, animal (5) 5
mice, knockout (5) 5
thrombosis - prevention & control (5) 5
hemostasis (4) 4
inflammation (4) 4
mechanisms (4) 4
platelets (4) 4
thrombosis - blood (4) 4
thrombosis - genetics (4) 4
collagen (3) 3
enzyme inhibitors - pharmacology (3) 3
hemostasis - drug effects (3) 3
male (3) 3
thrombosis - enzymology (3) 3
acute ischemic-stroke (2) 2
antibody (2) 2
article (2) 2
aufsatzsammlung (2) 2
blood clot (2) 2
blood platelets (2) 2
blood platelets - drug effects (2) 2
blood platelets - enzymology (2) 2
blood-flow (2) 2
cardiac & cardiovascular systems (2) 2
carotid artery diseases - blood (2) 2
carotid artery diseases - enzymology (2) 2
carotid artery diseases - genetics (2) 2
carotid artery diseases - prevention & control (2) 2
clinical neurology (2) 2
coronary circulation (2) 2
coronary disease - etiology (2) 2
dogs (2) 2
dose-response relationship, drug (2) 2
female (2) 2
fibrinolytic agents - pharmacology (2) 2
fty720 (2) 2
genetic predisposition to disease (2) 2
in-vivo (2) 2
infarction, middle cerebral artery - blood (2) 2
infarction, middle cerebral artery - enzymology (2) 2
infarction, middle cerebral artery - genetics (2) 2
infarction, middle cerebral artery - prevention & control (2) 2
integrin (2) 2
ischemia (2) 2
ischemic stroke (2) 2
islam (2) 2
mcao (2) 2
mice, transgenic (2) 2
microspheres (2) 2
microvascular dysfunction (2) 2
myocardial contraction - drug effects (2) 2
myocardium - pathology (2) 2
phenotype (2) 2
proteins (2) 2
receptor (2) 2
research article (2) 2
risk (2) 2
science (2) 2
signal transduction - drug effects (2) 2
sphingosine (2) 2
stroke (2) 2
syk (2) 2
syk kinase (2) 2
thrombo-inflammation (2) 2
thrombosis - physiopathology (2) 2
time factors (2) 2
tnf-alpha (2) 2
5-fluoro-2-indolyl des-chlorohalopemide (1) 1
<<ال>> إسلام (1) 1
<<ال>>إسلام (1) 1
adam10 (1) 1
adenosine (1) 1
adhesion (1) 1
administration, oral (1) 1
agglomeration (1) 1
aggregation (1) 1
alpha-granules (1) 1
amidohydrolases - antagonists & inhibitors (1) 1
analysis (1) 1
angioplasty (1) 1
anti-inflammatory agents - therapeutic use (1) 1
anticoagulants (1) 1
antithrombotic protection (1) 1
apoptosis - drug effects (1) 1
arabic philology (1) 1
arabisch (1) 1
arterial occlusive diseases - blood (1) 1
arterial occlusive diseases - drug therapy (1) 1
arterial occlusive diseases - enzymology (1) 1
arterial occlusive diseases - etiology (1) 1
arterial occlusive diseases - genetics (1) 1
arterial occlusive diseases - prevention & control (1) 1
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice
by Bender, Markus and May, Frauke and Lorenz, Viola and Thielmann, Ina and Hagedorn, Ina and Finney, Brenda A and Vögtle, Timo and Remer, Katharina and Braun, Attila and Bösl, Michael and Watson, Steve P and Nieswandt, Bernhard
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2013, Volume 33, Issue 5, pp. 926 - 934
OBJECTIVE—Platelet inhibition is a major strategy to prevent acute ischemic cardiovascular and cerebrovascular events, which may, however, be associated with... 
CLEC-2 | thrombosis | hemostasis | GPVI | platelets | COLLAGEN | IMMUNE THROMBOCYTOPENIC PURPURA | SYK | INTEGRIN | ANTIBODY | MECHANISMS | PERIPHERAL VASCULAR DISEASE | PLATELET ACTIVATION | HEMATOLOGY | ANTITHROMBOTIC PROTECTION | Platelet Membrane Glycoproteins - antagonists & inhibitors | Animals | Hemostasis | Mice, Inbred C57BL | Lectins, C-Type - physiology | Platelet Membrane Glycoproteins - physiology | Male | Mice | Thrombosis - prevention & control | Lectins, C-Type - antagonists & inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice
by Deppermann, Carsten and Cherpokova, Deya and Nurden, Paquita and Schulz, Jan-Niklas and Thielmann, Ina and Kraft, Peter and Vögtle, Timo and Kleinschnitz, Christoph and Dütting, Sebastian and Krohne, Georg and Eming, Sabine A and Nurden, Alan T and Eckes, Beate and Stoll, Guido and Stegner, David and Nieswandt, Bernhard
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3331 - 3342
Platelets are anuclear organelle-rich cell fragments derived from bone marrow megakaryocytes (MKs) that safeguard vascular integrity. The major platelet... 
MEDICINE, RESEARCH & EXPERIMENTAL | GLYCOPROTEIN-VI | ALPHA-GRANULES | BLEEDING-TIME | INTEGRIN | IN-VIVO | ARTERIAL THROMBOSIS | NBEAL2 | GROWTH-FACTOR | PROTEINS | ISCHEMIC-STROKE | Care and treatment | Genetic aspects | Diagnosis | Research | Gene expression | Blood platelet disorders | Thrombosis | Blood clot | Proteins | Wound healing | Heart attacks | Blood platelets | Microscopy | Colleges & universities | Defects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Normal platelet integrin function in mice lacking hydrogen peroxide-induced clone-5 (Hic-5)
by Popp, Michael and Thielmann, Ina and Nieswandt, Bernhard and Stegner, David
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0133429
Integrin alpha IIb beta 3 plays a central role in the adhesion and aggregation of platelets and thus is essential for hemostasis and thrombosis. Integrin... 
ADHESION | ACTIVATION | COLLAGEN | PROTEIN | THROMBOSIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MECHANISMS | BINDING | HEMOSTASIS | AGGREGATION | Paxillin - metabolism | Thrombosis - physiopathology | Hemostasis - physiology | Mice, Inbred C57BL | Platelet Activation - physiology | Cytoplasm - metabolism | Platelet Aggregation - physiology | Blood Platelets - physiology | Hydrogen Peroxide - metabolism | Mice, Knockout | Thrombosis - metabolism | Animals | Blood Platelets - metabolism | Focal Adhesions - metabolism | Platelet Glycoprotein GPIIb-IIIa Complex - metabolism | Female | Mice | Focal Adhesions - physiology | Flow cytometry | Immunoglobulins | Senescence | Hydrogen peroxide | Cloning | Glycoproteins | Platelet aggregation | Agglomeration | Thrombosis | Adhesion | Proteins | Medicine | Blood platelets | Hemostasis | Collagen | Stem cells | Ligands | Hemostatics | Thromboembolism | Platelets | Paxillin | Hydrogen ion concentration
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation
by Göb, Eva and Reymann, Stephan and Langhauser, Friederike and Schuhmann, Michael K and Kraft, Peter and Thielmann, Ina and Göbel, Kerstin and Brede, Marc and Homola, György and Solymosi, László and Stoll, Guido and Geis, Christian and Meuth, Sven G and Nieswandt, Bernhard and Kleinschnitz, Christoph
Annals of Neurology, ISSN 0364-5134, 05/2015, Volume 77, Issue 5, pp. 784 - 803
Objective Recent evidence suggests that ischemic stroke is a thromboinflammatory disease. Plasma kallikrein (PK) cleaves high–molecular‐weight kininogen to... 
ACTIVATION | INHIBITION | THROMBUS FORMATION | INFLAMMATION | ACUTE ISCHEMIC-STROKE | REGULATORY T-CELLS | REPERFUSION | MICE | NEUROSCIENCES | BRAIN | CLINICAL NEUROLOGY | PROTECTS | Plasma Kallikrein - metabolism | Stroke - prevention & control | Mice, Inbred C57BL | Plasma Kallikrein - antagonists & inhibitors | Male | Inflammation - blood | Stroke - genetics | Mice, Knockout | Brain Infarction - prevention & control | Stroke - blood | Plasma Kallikrein - genetics | Animals | Brain Infarction - blood | Inflammation - genetics | Female | Thrombosis - genetics | Inflammation - prevention & control | Mice | Thrombosis - blood | Thrombosis - prevention & control | Brain Infarction - genetics | Plasma | Stroke | Thrombosis | Rodents
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-infammation but not by direct neuroprotection
by Kraft, Peter and Göb, Eva and Schuhmann, Michael K and Göbel, Kerstin and Deppermann, Carsten and Thielmann, Ina and Herrmann, Alexander M and Lorenz, Kristina and Brede, Marc and Stoll, Guido and Meuth, Sven G and Nieswandt, Bernhard and Pfeilschifter, Waltraud and Kleinschnitz, Christoph
Stroke, ISSN 0039-2499, 11/2013, Volume 44, Issue 11, pp. 3202 - 3210
MCAO | Microvascular dysfunction | Inflammation | Ischemic stroke | Thrombo-inflammation | FTY720
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection
by Kraft, P and Gob, E and Schuhmann, MK and Gobel, K and Deppermann, C and Thielmann, I and Herrmann, AM and Lorenz, K and Brede, M and Stoll, G and Meuth, SG and Nieswandt, B and Pfeilschifter, W and Kleinschnitz, C
STROKE, ISSN 0039-2499, 11/2013, Volume 44, Issue 11, pp. 3202 - 3210
Background and Purpose Lymphocytes are important players in the pathophysiology of acute ischemic stroke. The interaction of lymphocytes with endothelial cells... 
MCAO | thrombo-inflammation | PROTECTION | INJURY | RECEPTOR | MECHANISMS | BLOOD-BRAIN-BARRIER | CLINICAL NEUROLOGY | RESPONSES | RECOVERY | microvascular dysfunction | inflammation | FTY720 | SPHINGOSINE-1-PHOSPHATE | PERIPHERAL VASCULAR DISEASE | FINGOLIMOD | ischemic stroke | T-LYMPHOCYTES | Neuroprotective Agents - therapeutic use | Propylene Glycols - pharmacology | Neurons - pathology | Brain Ischemia - therapy | Enzyme Inhibitors - pharmacology | Fingolimod Hydrochloride | Male | Mice, Transgenic | Middle Cerebral Artery - pathology | Lymphopenia - pathology | Homeodomain Proteins - genetics | Sphingosine - pharmacology | Inflammation - therapy | Sphingosine - analogs & derivatives | Animals | Lymphocytes - drug effects | Hypoxia | Mice | Immunosuppressive Agents - pharmacology | Stroke - therapy | Thrombosis - therapy | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Pharmacological Inhibition of Phospholipase D Protects Mice From Occlusive Thrombus Formation and Ischemic Stroke—Brief Report
by Stegner, David and Thielmann, Ina and Kraft, Peter and Frohman, Michael A and Stoll, Guido and Nieswandt, Bernhard
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2013, Volume 33, Issue 9, pp. 2212 - 2217
OBJECTIVE—We recently showed that mice lacking the lipid signaling enzyme phospholipase (PL) D1 or both PLD isoforms (PLD1 and PLD2) were protected from... 
phospholipase D | thrombosis | 5-fluoro-2-indolyl des-chlorohalopemide | cerebral stroke | PLATELETS | RISK | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | MOLECULAR-MECHANISMS | HALOPEMIDE | Carotid Artery Diseases - prevention & control | Infarction, Middle Cerebral Artery - physiopathology | Infarction, Middle Cerebral Artery - prevention & control | Carotid Artery Diseases - physiopathology | Blood Platelets - enzymology | Recovery of Function | Dose-Response Relationship, Drug | Time Factors | Infarction, Middle Cerebral Artery - genetics | Indoles - pharmacology | Phospholipase D - genetics | Thrombosis - blood | Thrombosis - prevention & control | Blood Platelets - drug effects | Domperidone - analogs & derivatives | Integrins - blood | Disease Models, Animal | Hemostasis - drug effects | Thrombosis - physiopathology | Phospholipase D - deficiency | Mice, Inbred C57BL | Thrombosis - enzymology | Enzyme Inhibitors - pharmacology | Phospholipase D - antagonists & inhibitors | Infarction, Middle Cerebral Artery - blood | Mice, Knockout | Fibrinolytic Agents - pharmacology | Animals | Carotid Artery Diseases - enzymology | Carotid Artery Diseases - blood | Carotid Artery Diseases - genetics | Domperidone - pharmacology | Thrombosis - genetics | Mice | Infarction, Middle Cerebral Artery - enzymology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP)
by Subramaniam, Saravanan and Thielmann, Ina and Morowski, Martina and Pragst, Ingo and Sandset, Per Morten and Nieswandt, Bernhard and Etscheid, Michael and Kanse, Sandip M
Thrombosis and Haemostasis, ISSN 0340-6245, 07/2015, Volume 113, Issue 4, pp. 870 - 880
Summary Factor VII (FVII) activating protease (FSAP) is a circulating protease with a putative function in blood coagulation and fibrinolysis. Genetic... 
Stroke, Systemic or Venous Thromboembolism | Haemostasis | Fibrinolysis | FSAP | Thrombosis | HABP2 | Coagulation | LIVER FIBROSIS | RISK | PROTEOLYSIS | fibrinolysis | thrombosis | haemostasis | G534E | PERIPHERAL VASCULAR DISEASE | MARBURG-I POLYMORPHISM | HEMATOLOGY | FACTOR PATHWAY INHIBITOR | Carotid Artery Diseases - prevention & control | Serine Endopeptidases - administration & dosage | Thrombosis - chemically induced | Carotid Artery Diseases - chemically induced | Mesenteric Vascular Occlusion - genetics | Venous Thromboembolism - blood | Chlorides | Serine Endopeptidases - genetics | Carotid Arteries - enzymology | Mesenteric Vascular Occlusion - enzymology | Thrombosis - blood | Thrombosis - prevention & control | Disease Models, Animal | Genetic Predisposition to Disease | Serine Endopeptidases - deficiency | Mesenteric Vascular Occlusion - prevention & control | Mice, Inbred C57BL | Thrombosis - enzymology | Hemostasis - genetics | Lipoproteins - blood | Mesenteric Vascular Occlusion - blood | Venous Thromboembolism - enzymology | Mice, Knockout | Ferric Compounds | Phenotype | Venous Thromboembolism - genetics | Animals | Carotid Artery Diseases - enzymology | Carotid Artery Diseases - blood | Collagen | Carotid Artery Diseases - genetics | Venous Thromboembolism - chemically induced | Blood Coagulation Tests | Thrombosis - genetics | Jugular Veins - enzymology | Norepinephrine | Mesenteric Vascular Occlusion - chemically induced | Mesenteric Arteries - enzymology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Altered BCR signalling quality predisposes to autoimmune disease and a pre‐diabetic state
by Königsberger, Sebastian and Prodöhl, Jan and Stegner, David and Weis, Vanessa and Andreas, Martin and Stehling, Martin and Schumacher, Theresa and Böhmer, Ruben and Thielmann, Ina and van Eeuwijk, Judith M M and Nieswandt, Bernhard and Kiefer, Friedemann
The EMBO Journal, ISSN 0261-4189, 08/2012, Volume 31, Issue 15, pp. 3363 - 3374
The spleen tyrosine kinase family members Syk and Zap‐70 are pivotal signal transducers downstream of antigen receptors and exhibit overlapping expression... 
B cell | autoimmunity | Syk | Zap‐70 | Zap-70 | B-CELL DEVELOPMENT | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIBODY | PROTEIN-TYROSINE KINASE | MARGINAL-ZONE | LECTIN RECEPTORS | CELL BIOLOGY | MICE | T-CELLS | Genetic Predisposition to Disease | Proto-Oncogene Proteins c-bcr - metabolism | Prediabetic State - genetics | Humans | Mice, Inbred C57BL | Cells, Cultured | B-Lymphocytes - physiology | ZAP-70 Protein-Tyrosine Kinase - genetics | Mice, Transgenic | Signal Transduction - genetics | Gene Knock-In Techniques | Autoimmune Diseases - genetics | Protein-Tyrosine Kinases - genetics | Animals | B-Lymphocytes - immunology | Proto-Oncogene Proteins c-bcr - physiology | Proto-Oncogene Proteins c-bcr - genetics | Mice | Gene Rearrangement, B-Lymphocyte - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | B-Lymphocytes - metabolism | Signal transduction | Diabetes | Autoimmune diseases | Kinases | Molecular biology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction
by van Eeuwijk, Judith M.M and Stegner, David and Lamb, David J and Kraft, Peter and Beck, Sarah and Thielmann, Ina and Kiefer, Friedemann and Walzog, Barbara and Stoll, Guido and Nieswandt, Bernhard
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 6, pp. 1247 - 1253
OBJECTIVE—Ischemic stroke, which is mainly caused by thromboembolic occlusion of brain arteries, is the second leading cause of death and disability worldwide... 
Syk kinase | thrombosis | mice | stroke | platelets | ACTIVATION | DISCOVERY | GLYCOPROTEIN VI | TRIAL | SPLEEN TYROSINE KINASE | ACUTE ISCHEMIC-STROKE | CHRONIC LYMPHOCYTIC-LEUKEMIA | PERIPHERAL VASCULAR DISEASE | SEPARATION | HEMATOLOGY | HEMOSTASIS | Arterial Occlusive Diseases - blood | Infarction, Middle Cerebral Artery - prevention & control | Brain - enzymology | Motor Activity - drug effects | Blood Platelets - enzymology | Syk Kinase - antagonists & inhibitors | Arterial Occlusive Diseases - genetics | Dose-Response Relationship, Drug | Time Factors | Syk Kinase - genetics | Infarction, Middle Cerebral Artery - genetics | Thrombosis - blood | Thrombosis - prevention & control | Blood Platelets - drug effects | Disease Models, Animal | Hemostasis - drug effects | Administration, Oral | Mice, Inbred C57BL | Thrombosis - enzymology | Genotype | Syk Kinase - deficiency | Arterial Occlusive Diseases - enzymology | Infarction, Middle Cerebral Artery - blood | Mice, Knockout | Brain - drug effects | Protein Kinase Inhibitors - administration & dosage | Phenotype | Animals | Signal Transduction - drug effects | Brain - pathology | Thrombosis - genetics | Fibrinolytic Agents - administration & dosage | Arterial Occlusive Diseases - prevention & control | Syk Kinase - blood | Infarction, Middle Cerebral Artery - enzymology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text FXIIa inhibitor rHA‐Infestin‐4: Safe thromboprotection in experimental venous, arterial and foreign surface‐induced thrombosis
by May, Frauke and Krupka, Jennifer and Fries, Marion and Thielmann, Ina and Pragst, Ingo and Weimer, Thomas and Panousis, Con and Nieswandt, Bernhard and Stoll, Guido and Dickneite, Gerhard and Schulte, Stefan and Nolte, Marc W
British Journal of Haematology, ISSN 0007-1048, 06/2016, Volume 173, Issue 5, pp. 769 - 778
Summary Haemostasis including blood coagulation is initiated upon vessel wall injury and indispensable to limit excessive blood loss. However, unregulated... 
coagulation factor XII | inhibitors | contact activation | Thrombosis | experimental animal models | Experimental animal models | Inhibitors | Contact activation | Coagulation factor XII | ACTIVATION | MECHANISMS | FACTOR-XII | SUPPORT | THERAPY | ROLES | TARGETS | HEMATOLOGY | CEREBRAL-ISCHEMIA | CONTACT PATHWAY | INFESTIN-4 | Hemostasis - drug effects | Rabbits | Insect Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Venous Thrombosis - drug therapy | Recombinant Fusion Proteins - therapeutic use | Treatment Outcome | Serum Albumin, Human | Venous Thrombosis - etiology | Arterial Occlusive Diseases - etiology | Serum Albumin - therapeutic use | Fibrinolytic Agents - pharmacology | Animals | Factor XIIa - antagonists & inhibitors | Serum Albumin - pharmacology | Arterial Occlusive Diseases - drug therapy | Thrombosis - etiology | Insect Proteins - therapeutic use | Mice | Thrombosis - drug therapy | Kinetics | Disease Models, Animal | Anticoagulants (Medicine) | Glycosaminoglycans | Analysis | Blood clot
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells
by Noy, PJ and Gavin, RL and Colombo, D and Haining, EJ and Reyat, JS and Payne, H and Thielmann, I and Lokman, AB and Neag, G and Yang, J and Lloyd, T and Harrison, N and Heath, VL and Gardiner, C and Whitworth, KM and Robinson, J and Koo, CZ and Di Maio, A and Harrison, P and Lee, SP and Michelangeli, F and Kalia, N and Rainger, GE and Nieswandt, B and Brill, A and Watson, SP and Tomlinson, MG
HAEMATOLOGICA, ISSN 0390-6078, 08/2019, Volume 104, Issue 9, pp. 1892 - 1905
Ca2+ entry via Orai1 store-operated Ca2+ channels in the plasma membrane is critical to cell function, and Orai1 loss causes severe immunodeficiency and... 
ACTIVATION | VWF | PORE | DEEP-VEIN THROMBOSIS | TETRASPANIN | ADAM10 | PLATELET-ADHESION | HEMATOLOGY | MYOCARDIAL ISCHEMIA/REPERFUSION INJURY | HEMOSTASIS | CRAC CHANNEL | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation
: Plasma Kallikrein and Stroke
by Göb, Eva and Reymann, Stephan and Langhauser, Friederike and Schuhmann, Michael K and Kraft, Peter and Thielmann, Ina and Göbel, Kerstin and Brede, Marc and Homola, György and Solymosi, László and Stoll, Guido and Geis, Christian and Meuth, Sven G and Nieswandt, Bernhard and Kleinschnitz, Christoph
Annals of Neurology, ISSN 0364-5134, 05/2015, Volume 77, Issue 5, pp. 784 - 803
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Myocardial Dysfunction With Coronary Microembolization: Signal Transduction Through a Sequence of Nitric Oxide, Tumor Necrosis Factor-α, and Sphingosine
by Thielmann, Matthias and Dörge, Hilmar and Martin, Claus and Belosjorow, Sergej and Schwanke, Uwe and van de Sand, Anita and Konietzka, Ina and Büchert, Astrid and Krüger, Arne and Schulz, Rainer and Heusch, Gerd
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 04/2002, Volume 90, Issue 7, pp. 807 - 813
Coronary microembolization results in progressive myocardial dysfunction, with causal involvement of tumor necrosis factor-α (TNF-α). TNF-α uses a signal... 
Coronary microembolization | Tumor necrosis factor-α | Nitric oxide | Sphingosine | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | ADENOSINE | ISCHEMIA | RECEPTOR | BLOOD-FLOW | sphingosine | tumor necrosis factor-alpha | HEART | CELLULAR BASIS | ANGIOPLASTY | PERIPHERAL VASCULAR DISEASE | coronary microembolization | TNF-ALPHA | HEMATOLOGY | EXPRESSION | DISTAL EMBOLIZATION | Tumor Necrosis Factor-alpha - metabolism | Ethanolamines - pharmacology | Apoptosis - drug effects | Myocardial Contraction - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Coronary Disease - physiopathology | Nitric Oxide Synthase - genetics | RNA, Messenger - metabolism | Nitric Oxide Synthase Type II | Embolism - physiopathology | Microspheres | Ceramidases | Myocardium - metabolism | Leukocyte Count | Sphingosine - metabolism | Endocannabinoids | Disease Models, Animal | Coronary Circulation | NG-Nitroarginine Methyl Ester - pharmacology | Embolism - complications | Enzyme Inhibitors - pharmacology | Coronary Disease - etiology | Oleic Acids | Amidohydrolases - antagonists & inhibitors | Myocardium - pathology | Coronary Disease - pathology | Animals | Signal Transduction - drug effects | Blood Flow Velocity | Dogs | Nitric Oxide Synthase - metabolism | Nitric Oxide - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state
: Altered BCR signalling quality elicits autoimmunity
by Königsberger, Sebastian and Prodöhl, Jan and Stegner, David and Weis, Vanessa and Andreas, Martin and Stehling, Martin and Schumacher, Theresa and Böhmer, Ruben and Thielmann, Ina and van Eeuwijk, Judith M M and Nieswandt, Bernhard and Kiefer, Friedemann
The EMBO Journal, ISSN 0261-4189, 08/2012, Volume 31, Issue 15, pp. 3363 - 3374
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice
by Deppermann, Carsten and Cherpokova, Deya and Nurden, Paquita and Schulz, Jan-Niklas and Thielmann, Ina and Kraft, Peter and Vogtle, Timo and Kleinschnitz, Christoph and Duetting, Sebastian and Krohne, Georg and Eming, Sabine A and Nurden, Alan T and Eckes, Beate and Stoll, Guido and Stegner, David and Nieswandt, Bernhard
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3331 - 3331
Platelets are anuclear organelle-rich cell fragments derived from bone marrow megakaryocytes (MKs) that safeguard vascular integrity. The major platelet... 
Journal Article
Details down arrow
17. Full Text Tspan18 is a novel regulator of the Ca 2+ channel Orai1 and von Willebrand factor release in endothelial cells
by Noy, Peter J and Gavin, Rebecca L and Colombo, Dario and Haining, Elizabeth J and Reyat, Jasmeet S and Payne, Holly and Thielmann, Ina and Lokman, Adam B and Neag, Georgiana and Yang, Jing and Lloyd, Tammy and Harrison, Neale and Heath, Victoria L and Gardiner, Chris and Whitworth, Katharine M and Robinson, Joseph and Koo, Chek Z and Di Maio, Alessandro and Harrison, Paul and Lee, Steven P and Michelangeli, Francesco and Kalia, Neena and Rainger, G Ed and Nieswandt, Bernhard and Brill, Alexander and Watson, Steve P and Tomlinson, Michael G
Haematologica, 09/2019, Volume 104, Issue 9, p. 1892
Ca entry Orai1 store-operated Ca channels in the plasma membrane is critical to cell function, and Orai1 loss causes severe immunodeficiency and developmental... 
Journal Article
Details