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Nature Genetics, ISSN 1061-4036, 08/2018, Volume 50, Issue 8, p. 1122
The molecular mechanisms underpinning susceptibility loci for type 2 diabetes (T2D) remain poorly understood. Coding variants in peptidylglycine... 
Type 2 diabetes | Pancreatic beta cells | Genetic aspects | Research | Gene expression | Risk factors
Journal Article
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 08/2014, Volume 25, Issue 8, p. 425
acents Genes involved in pancreatic development are implicated in Mendelian diabetes. acents Studying the genetic basis of diabetes has delivered insights into... 
Pancreatic beta cells | Genetics | Cells
Journal Article
by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and Rayner, N. William and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Anew T and van Dam, Rob M and Doney, Alex S. F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and DIAbet Genetics Replication Meta-A and DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten and Stockholms universitet and Science for Life Laboratory (SciLifeLab)
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 12, pp. 1415 - +
We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct... 
TRANSCRIPTION FACTORS | COMMON VARIANTS | HUMAN PANCREATIC-ISLETS | GLUCOSE-HOMEOSTASIS | GENOTYPE IMPUTATION | LARGE-SCALE ASSOCIATION | INSULIN-SECRETION | GENETICS & HEREDITY | GLYCEMIC TRAITS | BETA-CELL | WIDE ASSOCIATION | Hepatocyte Nuclear Factor 3-beta - metabolism | Receptor, Melatonin, MT2 - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Liver - pathology | Hepatocyte Nuclear Factor 3-beta - genetics | Islets of Langerhans - pathology | Diabetes Mellitus, Type 2 - genetics | Genomics | Humans | Liver - metabolism | Molecular Sequence Annotation | Gene Expression Regulation | Chromosome Mapping | Genetic Loci | Case-Control Studies | Chromatin Immunoprecipitation | Islets of Langerhans - metabolism | Polymorphism, Single Nucleotide - genetics | Receptor, Melatonin, MT2 - metabolism | Binding Sites | Type 2 diabetes | Quantitative trait loci | Chromosome mapping | Genetic susceptibility | Genetic research | Development and progression | Genetic aspects | Research | Identification and classification | Methods | Studies | Haplotypes | Genealogy | Biomedical research | Genomes | Localization | Meta-analysis | Genetik | Basic Medicine | Medical Genetics | Medicinsk genetik | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Genetics | Natural Sciences
Journal Article
Journal Article
Journal Article
2017
Genome-wide association studies (GWAS) have identified more than 150 loci associated with type 2 diabetes (T2D) risk. Most association signals are located in... 
Dissertation