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2003, Advanced Texts, ISBN 9781859960547, xiv, 298
Bioinformatics, the use of computers to address biological questions, has become an essential tool in biological research. It is one of the critical keys... 
Amino acid sequence | Genetics -- Data processing | Proteins -- Structure | Bioinformatics | Bio-informatique | Communication Studies | Sequence Analysis | Genomics | Methods | Computational Biology | Proteomics
Book
1992, ISBN 0199633622, 2 v. (827 p.)
Book
Nucleic Acids Research, ISSN 0305-1048, 01/2018, Volume 46, Issue D1, pp. D618 - D623
Abstract M-CSA (Mechanism and Catalytic Site Atlas) is a database of enzyme active sites and reaction mechanisms that can be accessed at... 
MACIE | PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERSPECTIVES | ALGORITHM | CLASSIFICATION | RESIDUES | TEMPLATES | RESOURCE | TOOLS | Enzymes - chemistry | User-Computer Interface | Catalytic Domain | Biocatalysis | Data Curation | Databases, Protein | Humans | Internet | Enzymes - metabolism | Web Browser | Database Issue
Journal Article
Protein Science, ISSN 0961-8368, 10/2019
Journal Article
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 02/2019, Volume 30, Issue 2, pp. 118 - 131
Increasing human life expectancy has posed increasing challenges for healthcare systems. As people age, they become more susceptible to chronic diseases, with... 
computational biology | longevity | ageing | drug repurposing | FDA-APPROVED DRUGS | SURVIVAL | NETWORK | DATABASE | GENE | CALORIC RESTRICTION | ENDOCRINOLOGY & METABOLISM | EXTEND LIFE-SPAN | MODEL | ASSOCIATION | AGE
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 02/2019, Volume 35, Issue 18, pp. 3510 - 3511
Cofactors are essential for many enzyme reactions. The Protein Data Bank (PDB) contains >67,000 entries containing enzyme structures, many with bound cofactor... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Applications Notes
Journal Article
Bioinformatics, ISSN 1367-4803, 10/2018, Volume 34, Issue 20, pp. 3597 - 3599
Abstract Motivation One goal of synthetic biology is to make new enzymes to generate new products, but identifying the starting enzymes for further... 
PROMISCUITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Applications Notes
Journal Article
SCIENCE SIGNALING, ISSN 1945-0877, 08/2019, Volume 12, Issue 594, p. eaat9797
The 21st century is witnessing an explosive surge in our understanding of pseudoenzyme-driven regulatory mechanisms in biology. Pseudoenzymes are proteins that... 
CAENORHABDITIS-ELEGANS | ENZYME | MECHANISM | CRYSTAL-STRUCTURE | PROTEIN-KINASE | COMPLEX REVEALS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PSEUDOKINASES | MOLECULAR SWITCH | CHITOOLIGOSACCHARIDE-BINDING | ALLOSTERIC ACTIVATION | CELL BIOLOGY | Signal classification
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 06/2019
Understanding the protein structural context and patterning on proteins of genomic variants can help to separate benign from pathogenic variants and reveal... 
Journal Article
2012, Images of America
Champion, Great Bend, and Deferiet were all founded in the 1800s. Farming has always been the lifeblood of Champion; Noadiah Hubbard--original settler, land... 
Historic buildings | Champion (N.Y.) History | Jefferson County (N.Y.) Social life and customs | Great Bend (N.Y.) History | Deferiet (N.Y.) History | Jefferson County (N.Y.) Biography | Jefferson County (N.Y.) History, Local | Dwellings
Web Resource
Acta Crystallographica Section A Foundations and Advances, ISSN 2053-2733, 12/2017, Volume 73, Issue a2, pp. C972 - C972
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 01/2001, Volume 42, Issue 1, pp. 108 - 124
Evolutionary information derived from the large number of available protein sequences and structures could powerfully guide both analysis and prediction of... 
molecular recognition | oligomeric interfaces | residue conservation | Residue conservation | Molecular recognition | Oligomeric interfaces
Journal Article