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by Agrawal, Nishant and Akbani, Rehan and Aksoy, B. Arman and Ally, Adrian and Arachchi, Harindra and Asa, Sylvia L and Auman, J. Todd and Balasundaram, Miruna and Balu, Saianand and Baylin, Stephen B and Behera, Madhusmita and Bernard, Brady and Beroukhim, Rameen and Bishop, Justin A and Black, Aaron D and Bodenheimer, Tom and Boice, Lori and Bootwalla, Moiz S and Bowen, Jay and Bowlby, Reanne and Bristow, Christopher A and Brookens, Robin and Brooks, Denise and Bryant, Robert and Buda, Elizabeth and Butterfield, Yaron S.N and Carling, Tobias and Carlsen, Rebecca and Carter, Scott L and Carty, Sally E and Chan, Timothy A and Chen, Amy Y and Cherniack, Andrew D and Cheung, Dorothy and Chin, Lynda and Cho, Juok and Chu, Andy and Chuah, Eric and Cibulskis, Kristian and Ciriello, Giovanni and Clarke, Amanda and Clayman, Gary L and Cope, Leslie and Copland, John A and Covington, Kyle and Danilova, Ludmila and Davidsen, Tanja and Demchok, John A and DiCara, Daniel and Dhalla, Noreen and Dhir, Rajiv and Dookran, Sheliann S and Dresdner, Gideon and Eldridge, Jonathan and Eley, Greg and El-Naggar, Adel K and Eng, Stephanie and Fagin, James A and Fennell, Timothy and Ferris, Robert L and Fisher, Sheila and Frazer, Scott and Frick, Jessica and Gabriel, Stacey B and Ganly, Ian and Gao, Jianjiong and Garraway, Levi A and Gastier-Foster, Julie M and Getz, Gad and Gehlenborg, Nils and Ghossein, Ronald and Gibbs, Richard A and Giordano, Thomas J and Gomez-Hernandez, Karen and Grimsby, Jonna and Gross, Benjamin and Guin, Ranabir and Hadjipanayis, Angela and Harper, Hollie A and Hayes, D. Neil and Heiman, David I and Herman, James G and Hoadley, Katherine A and Hofree, Matan and Holt, Robert A and Hoyle, Alan P and Huang, Mei and Huang, Franklin W and Hutter, Carolyn M and Ideker, Trey and Iype, Lisa and Jacobsen, Anders and Jefferys, Stuart R and Jones, Corbin D and Jones, Steven J.M and Kasaian, Katayoon and Kebebew, Electron and Khuri, Fadlo R and Kim, Jaegil and Kramer, Roger and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell, ISSN 0092-8674, 10/2014, Volume 159, Issue 3, pp. 676 - 690
Journal Article
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1141 - 1147
Journal Article
by Bass, Adam J and Cancer Genome Atlas Research Network, Genome Atlas Research Network and Thorsson, Vesteinn and Shmulevich, Ilya and Reynolds, Sheila M and Miller, Michael and Bernard, Brady and Hinoue, Toshinori and Laird, Peter W and Curtis, Christina and Shen, Hui and Weisenberger, Daniel J and Schultz, Nikolaus and Shen, Ronglai and Weinhold, Nils and Kelsen, David P and Bowlby, Reanne and Chu, Andy and Kasaian, Katayoon and Mungall, Andrew J and Robertson, A. Gordon and Sipahimalani, Payal and Cherniack, Andrew D and Getz, Gad and Liu, Yingchun and Noble, Michael S and Pedamallu, Chandra and Sougnez, Carrie and Taylor-Weiner, Amaro and Akbani, Rehan and Lee, Ju-Seog and Liu, Wenbin and Mills, Gordon B and Yang, Da and Zhang, Wei and Pantazi, Angeliki and Parfenov, Michael and Gulley, Margaret and Piazuelo, M. Blanca and Schneider, Barbara G and Kim, Jihun and Boussioutas, Alex and Sheth, Margi and Demchok, John A and Rabkin, Charles S and Willis, Joseph E and Ng, Sam and Garman, Katherine and Beer, David G and Pennathur, Arjun and Raphael, Benjamin J and Wu, Hsin-Ta and Odze, Robert and Kim, Hark K and Bowen, Jay and Leraas, Kristen M and Lichtenberg, Tara M and Weaver, Stephanie and McLellan, Michael and Wiznerowicz, Maciej and Sakai, Ryo and Lawrence, Michael S and Cibulskis, Kristian and Lichtenstein, Lee and Fisher, Sheila and Gabriel, Stacey B and Lander, Eric S and Ding, Li and Niu, Beifang and Ally, Adrian and Balasundaram, Miruna and Birol, Inanc and Brooks, Denise and Butterfield, Yaron S. N and Carlsen, Rebecca and Chu, Justin and Chuah, Eric and Chun, Hye-Jung E and Clarke, Amanda and Dhalla, Noreen and Guin, Ranabir and Holt, Robert A and Jones, Steven J. M and Lee, Darlene and Li, Haiyan A and Lim, Emilia and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Karen L and Nip, Ka Ming and Schein, Jacqueline E and Tam, Angela and Thiessen, Nina and Beroukhim, Rameen and Carter, Scott L and Cho, Juok and DiCara, Daniel and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7517, pp. 202 - 209
Journal Article
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Index Medicus | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
by Saltz, Joel and Gupta, Rajarsi and Hou, Le and Kurc, Tahsin and Singh, Rosy and Singh, Pankaj and Singh, Bhuvanesh and Nguyen, Phuong and Nguyen, Vu and Samaras, Dimitris and Shroyer, Kenneth R and Zhao, Tianhao and Zhao, Fengmei and Batiste, Rebecca and Van Arnam, John and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Min and Wang, Jing and Wang, Jioajiao and Wang, Timothy and Wang, Zhining and Wang, Linghua and Yang, Liming and Yang, Ian and Yang, Hannah and Yang, Ju Dong and Zenklusen, Jean C and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Zhang, Jiexin and Zhang, Jiashan (Julia) and Zhang, Lizhi and Chudamani, Sudha and Liu, Yuexin and Liu, Xiuping and Liu, Wenbin and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Judy and Miller, Christopher A and Miller, Michael and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Thorsson, Vésteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Li, Wei and Liang, Han and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind U.K and Rao, Arvind and Ryan, Michael and Weinstein, John N and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 181 - 193.e7
Beyond sample curation and basic pathologic characterization, the digitized H&E-stained images of TCGA samples remain underutilized. To highlight this... 
deep learning | lymphocytes | digital pathology | bioinformatics | computer vision | tumor-infiltrating lymphocytes | immuno-oncology | tumor microenvironment | machine learning | artificial intelligence | MELANOMA | IMMUNE CONTEXTURE | GENOMIC ANALYSES | SOLID TUMORS | SUBTYPES | SQUAMOUS-CELL CARCINOMA | PROPOSAL | CANCER | STANDARDIZED METHOD | BREAST | CELL BIOLOGY
Journal Article