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ChemMedChem, ISSN 1860-7179, 2015, Volume 10, Issue 10, pp. 1635 - 1640
A series of novel fluorine‐containing cyclooxygenase‐2 (COX‐2) inhibitors was designed and synthesized based on the previously reported fluorescent COX‐2... 
cancer | positron emission tomography | drug design | cyclooxygenases | radiochemistry
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 07/2018, Volume 62, p. 9
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.nucmedbio.2018.05.001... 
COX-2 inhibitors | Pyrimidines
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 07/2018, Volume 62-63, pp. 9 - 17
Introduction: Non-invasive imaging of COX-2 in cancer represents a powerful tool for assessing COX-2-mediated effects on chemoprevention and radiosensitization... 
Positron emission tomography (PET) | Fluorine-18 | Radiopharmacology | Cyclooxygenase-2 (COX-2)
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 07/2018, Volume 62-63, pp. 9 - 17
Non-invasive imaging of COX-2 in cancer represents a powerful tool for assessing COX-2-mediated effects on chemoprevention and radiosensitization using potent... 
Positron emission tomography (PET) | Fluorine-18 | Radiopharmacology | Cyclooxygenase-2 (COX-2) | Index Medicus
Journal Article
ISSN 1477-0520, 7/2016, Volume 14, Issue 3, pp. 725 - 7257
The cyclooxygenase-2 (COX-2) enzyme is overexpressed in a variety of cancers and mediates inflammatory processes that aid the growth and progression of... 
Journal Article
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 2016, Volume 26, Issue 6, pp. 1516 - 1520
Cyclooxygenase-2 (COX-2) is the key enzyme in the prostaglandin synthesis pathway which is involved in various pathophysiological conditions. The enzyme is... 
Fluorous chemistry | Iodine-125 | Cyclooxygenase-2
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P148 - P148
Journal Article
EJNMMI Research, ISSN 2191-219X, 12/2016, Volume 6, Issue 1, pp. 1 - 11
Cyclooxygenase-2 (COX-2) is the inducible isoform of the cyclooxygenase enzyme family. COX-2 is involved in tumor development and progression, and frequent... 
Positron emission tomography (PET) | COX-2 inhibitor | Medicine & Public Health | Orthopedics | Colorectal cancer | Oncology | Nuclear Medicine | Imaging / Radiology | Cardiology | Cyclooxygenase-2 (COX-2) | TARGET | TUMOR | CELECOXIB | POSITRON-EMISSION-TOMOGRAPHY | INFLAMMATION | DISEASE | INHIBITORS | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 03/2016, Volume 26, Issue 6, pp. 1516 - 1520
A novel I-containing trifluoro-pyrimidine compound ([ I]Pyricoxib) as potent and selective COX-2 inhibitor was prepared via radioiodo-destannylation reaction... 
Fluorous chemistry | Iodine-125 | Cyclooxygenase-2
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 03/2016, Volume 26, Issue 6, p. 1516
A novel.sup.125I-containing trifluoro-pyrimidine compound ([.sup.125I]Pyricoxib) as potent and selective COX-2 inhibitor was prepared via... 
COX-2 inhibitors
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 03/2016, Volume 26, Issue 6, pp. 1516 - 1520
Journal Article
ChemMedChem, ISSN 1860-7179, 10/2015, Volume 10, Issue 10, p. 1635
A series of novel fluorine-containing cyclooxygenase-2 (COX-2) inhibitors was designed and synthesized based on the previously reported fluorescent COX-2... 
COX-2 inhibitors | PET imaging | Pharmacy | Colorectal cancer | Angiogenesis inhibitors | Fluorides | Celecoxib
Journal Article
American journal of nuclear medicine and molecular imaging, ISSN 2160-8407, 2013, Volume 3, Issue 4, pp. 372 - 383
The G-protein coupled C-X-C chemokine receptor type 4 (CXCR4) is highly overexpressed in a range of cancers and is therefore an excellent biomarker for cancer... 
Journal Article
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