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Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 179 - 185
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7534, pp. 381 - 385
Despite antiretroviral therapy (ART), human immunodeficiency virus (HIV)-1 persists in a stable latent reservoir(1,2), primarily in resting memory CD4(+) T... 
IMMUNODOMINANCE | VIREMIA | DESIGN | VIRUS | RECOGNITION | STABILITY | MULTIDISCIPLINARY SCIENCES | VACCINE | ANTIRETROVIRAL THERAPY | INFECTION | VIRAL RESERVOIR | Anti-HIV Agents - pharmacology | Humans | Epitopes, T-Lymphocyte - genetics | Male | RNA, Viral - blood | Anti-HIV Agents - administration & dosage | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV-1 - growth & development | Genes, Viral - genetics | Anti-HIV Agents - therapeutic use | Female | Epitopes, T-Lymphocyte - immunology | gag Gene Products, Human Immunodeficiency Virus - genetics | CD4-Positive T-Lymphocytes - virology | Chronic Disease - drug therapy | HIV Infections - blood | T-Lymphocytes, Cytotoxic - immunology | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | Virus Replication - immunology | Acute Disease - therapy | HIV-1 - genetics | Mutation - genetics | HIV-1 - immunology | Animals | HIV Infections - drug therapy | Mice | Viral Load - drug effects | Virus Latency - immunology | gag Gene Products, Human Immunodeficiency Virus - immunology | Genes, Dominant - genetics | Virus Latency - genetics | Immune response | AIDS treatment | AIDS (Disease) | Physiological aspects | Research | AIDS research | T cells | Properties | Antigens | Peptides | Lymphocytes | Human immunodeficiency virus--HIV | Infections | Mutation | Gene expression | Patients | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 50, pp. 21635 - 21640
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 24, pp. 9862 - 9867
The microbiota is pivotal in the pathogenesis of inflammatory bowel disease (IBD)-associated inflammation-induced colorectal cancer (CRC), yet mechanisms for... 
Microorganisms | Microbiota | Receptors | Epithelial cells | Colorectal cancer | Mice | Inflammation | Colitis | Tumors | Cancer | colon cancer | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | COLITIS-ASSOCIATED CANCER | NLRP3 INFLAMMASOME | INTESTINAL INFLAMMATION | ASC | COLORECTAL-CANCER | DISEASE | COLON INFLAMMATION | MICE | GUT FLORA | TUMORIGENESIS | microflora | Neoplasms - metabolism | Interleukin-18 - immunology | Inflammasomes - metabolism | Colitis - genetics | Colorectal Neoplasms - genetics | Male | Chemokine CCL5 - deficiency | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Neoplasms - genetics | Colonoscopy | Epithelium - microbiology | Female | Colitis - immunology | Interleukin-6 - metabolism | Colorectal Neoplasms - metabolism | Epithelium - metabolism | Interleukin-6 - genetics | Mice, Inbred C57BL | Interleukin-18 - deficiency | Inflammation - immunology | Receptors, Cell Surface - immunology | Mice, Knockout | Animals | Colorectal Neoplasms - immunology | Neoplasms - immunology | Inflammasomes - immunology | Receptors, Cell Surface - deficiency | Chemokine CCL5 - genetics | Colitis - metabolism | Interleukin-6 - immunology | Inflammation - genetics | Metagenome - immunology | Interleukin-18 - genetics | Chemokine CCL5 - immunology | Receptors, Cell Surface - genetics | Physiological aspects | Development and progression | Health aspects | Interleukin-6 | Inflammatory bowel disease | Cytokines | Microbiology | Pathogenesis | Chemokines | Index Medicus | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 603 - 604
In light of this inter-facility microbiome variability, littermate approaches must be coupled to a second important step involving generation of germ-free... 
SHAPE | MICE | IMMUNOLOGY | GUT MICROBIOTA COMPOSITION | Dysbacteriosis | Microbiota | Feces | Rodents | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 01/2013, Volume 110, Issue 5, pp. 1851 - 1856
A flagellin-independent caspase-1 activation pathway that does not require NAIP5 or NRLC4 is induced by the intracellular pathogen Legionella pneumophila .... 
Cell death | Innate immunity | Inflammasome | PATTERN-RECOGNITION | innate immunity | cell death | inflammasome | MULTIDISCIPLINARY SCIENCES | NLRP3 INFLAMMASOME ACTIVATION | INFECTION | RECEPTORS | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Adaptor Proteins, Vesicular Transport - genetics | Caspase 1 - metabolism | Immunoblotting | Legionella pneumophila - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Necrosis | Caspases - metabolism | Flagellin - genetics | Flagellin - metabolism | Apoptosis Regulatory Proteins - genetics | Cytoskeletal Proteins - metabolism | Receptor, Interferon alpha-beta - genetics | Macrophages - microbiology | Receptor, Interferon alpha-beta - metabolism | Calcium-Binding Proteins - metabolism | Cytokines - metabolism | Caspases - genetics | Mice, Inbred C57BL | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Macrophages - cytology | Legionella pneumophila - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Host-Pathogen Interactions | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Bone Marrow Cells - microbiology | Legionella pneumophila - physiology | Mice | Enzyme Activation | Mutation | Myeloid Differentiation Factor 88 - metabolism | Bone Marrow Cells - metabolism | Apoptosis | Calcium-Binding Proteins - genetics | Legionella pneumophila | Genetic aspects | Research | Macrophages | Properties | Immunological research | Proteins | Bacteria | Medical treatment | Cells | Index Medicus | Biological Sciences
Journal Article
Science, ISSN 0036-8075, 11/2016, Volume 354, Issue 6313, pp. 765 - 768
Journal Article
Cell Reports, ISSN 2211-1247, 12/2017, Volume 21, Issue 13, pp. 3914 - 3926
Contradicting observations have been made regarding the relative contributions of immune sensors to shaping the microbiome, yet the reasons for these... 
intestinal microbiota | familial transmission | adaptive immunity | gut biogeography | host-microbiota interaction | Nlrp6 | CELLS | ACTIVATION | IMMUNOGLOBULIN-A | COMMENSAL BACTERIA | COLITIS | SEQUENCES | INFLAMMATION | DISEASE | GUT MICROBIOTA | INNATE IMMUNITY | CELL BIOLOGY | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 55 - 55
Journal Article
PLoS Pathogens, ISSN 1553-7366, 06/2013, Volume 9, Issue 6, pp. e1003400 - e1003400
Inflammasome activation is important for antimicrobial defense because it induces cell death and regulates the secretion of IL-1 family cytokines, which play a... 
LEGIONELLA-PNEUMOPHILA | FLAGELLIN | PROTEIN | DISTINCT PATHWAYS | RECOGNITION | INFLAMMASOME ACTIVATION | INTERLEUKIN-1-BETA | INNATE | LEGIONNAIRES DISEASE | MICROBIOLOGY | DIFFERENTIAL REQUIREMENT | VIROLOGY | PARASITOLOGY | Interleukin-1alpha - immunology | Caspases - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Cytosol - immunology | Enzyme Activation - immunology | Legionnaires' Disease - immunology | Calcium-Binding Proteins - immunology | Legionnaires' Disease - microbiology | Legionella pneumophila - pathogenicity | Bacterial Secretion Systems - immunology | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Cell Line | Legionella pneumophila - immunology | Apoptosis Regulatory Proteins - immunology | Macrophages - pathology | Caspases - genetics | Interleukin-1beta - immunology | Inflammasomes - genetics | Mice, Knockout | Immunity, Innate - immunology | Animals | Inflammasomes - immunology | Legionnaires' Disease - pathology | Cytosol - microbiology | Mice | Host-parasite relationships | Physiological aspects | Research | Interleukins | Cytosol | Health aspects | Index Medicus | Bacterial infections | Microbiology | Cytokines | Infections | Experiments | Bacteriology | Recruitment | Scholarships & fellowships | E coli | Bone marrow | Bacteria | Interferon | Gram-negative bacteria | Adapter proteins | Apoptosis
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 05/2019, Volume 78, Issue 5, pp. 590 - 593
ObjectivesRheumatoid arthritis (RA) has been associated with a relative expansion of faecal Prevotellaceae. To determine the microbiome composition and... 
epidemiology of ra | pre-clinical stages of ra | microbiome | rheumatoid arthritis | RELATIVES | RHEUMATOLOGY | Dysbacteriosis | Autoantibodies | Statistical analysis | Rheumatology | Microbiomes | Studies | Proteins | Rheumatoid factor | Hypotheses | Microbiota | Intestine | Rheumatoid arthritis | Questionnaires | Population | Age | Deoxyribonucleic acid--DNA
Journal Article