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Antibodies, ISSN 2073-4468, 12/2018, Volume 7, Issue 4, p. 43
Upregulation of the expression of tumor necrosis factor (TNF-α, TNF) has a significant role in the development of autoimmune diseases. The fluorescent... 
Binding | Antigens | Immunoglobulins | Disease | Pathogenesis | Red fluorescent protein | Antibodies | Fluorescence | Biochemistry | Arthritis | Tumor necrosis factor-α | Proteins | TNF inhibitors | Tumor necrosis factor-TNF | Mice | Molecular biology | Autoimmune diseases | Deoxyribonucleic acid--DNA | Recombinant | anti-cytokine therapy | sensor | nanobodies | TNF | autoimmune disease | fluorescent
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 11, pp. 3006 - 3011
Overexpression of TNF contributes to pathogenesis of multiple autoimmune diseases, accounting for a remarkable success of anti- TNF therapy. TNF is produced by... 
Autoimmunity | Bispecific antibody | Humanized mice | TNF | Anti-cytokine therapy | RHEUMATOID-ARTHRITIS | MYCOBACTERIUM-TUBERCULOSIS | CROHNS-DISEASE | CONTROLLED MULTICENTER | MULTIDISCIPLINARY SCIENCES | humanized mice | ULCERATIVE-COLITIS | ANKYLOSING-SPONDYLITIS | SINGLE-DOMAIN ANTIBODIES | FACTOR-ALPHA | TUMOR-NECROSIS-FACTOR | autoimmunity | bispecific antibody | anti-cytokine therapy | PLAQUE-TYPE PSORIASIS | Recombinant Fusion Proteins - immunology | Antibody Specificity | Complementarity Determining Regions - genetics | Humans | L Cells (Cell Line) | Antibodies, Bispecific - genetics | Antigen-Antibody Reactions | Camelus - immunology | Antibodies, Neutralizing - immunology | Single-Chain Antibodies - genetics | Complementarity Determining Regions - chemistry | Chemical and Drug Induced Liver Injury - etiology | Chemical and Drug Induced Liver Injury - prevention & control | Tumor Necrosis Factor-alpha - secretion | Genes, Synthetic | Macrophages, Peritoneal - immunology | Antibodies, Neutralizing - genetics | Random Allocation | Macrophages, Peritoneal - secretion | Antibodies, Bispecific - immunology | Chemical and Drug Induced Liver Injury - immunology | Animals | Chemical and Drug Induced Liver Injury - therapy | Complementarity Determining Regions - immunology | Recombinant Fusion Proteins - genetics | Antigens, Differentiation - genetics | Mice | Mutation | Antigens, Surface - immunology | Galactosamine - toxicity | Single-Chain Antibodies - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Amino Acid Substitution | Antigens, Differentiation - immunology | Care and treatment | Tumor necrosis factor | Genetic aspects | Gene expression | Observations | Autoimmune diseases | Health aspects | Biological Sciences
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 09/2017, Volume 8, p. 1073
Proinflammatory cytokines, such as TNF, IL-6, and IL-1, play pathogenic roles in multiple diseases and are attractive targets for biologic drugs. Because... 
DISTINCT | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | SINGLE-DOMAIN ANTIBODIES | TNF | IL-6 | CD8(+) T-CELLS | macrophages | INHIBITION | SELECTIVE BLOCKADE | VHH | MICE | single-chain antibodies | EXPRESSION | Single-chain antibodies | Macrophages
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2016, Volume 113, Issue 11, p. 3006
  Overexpression of TNF contributes to pathogenesis of multiple autoimmune diseases, accounting for a remarkable success of anti-TNF therapy. TNF is produced... 
Molecules | Cytokines | Pathogenesis | Rodents | Gene expression | Cells | Binding sites
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 03/2016, Volume 113, Issue 11, pp. 3006 - 3006
Overexpression of TNF contributes to pathogenesis of multiple autoimmune diseases, accounting for a remarkable success of anti-TNF therapy. TNF is produced by... 
Journal Article
Science, ISSN 0036-8075, 11/2001, Volume 294, Issue 5545, pp. 1331 - 1334
Journal Article
Journal Article
Antiviral Research, ISSN 0166-3542, 03/2013, Volume 97, Issue 3, pp. 245 - 254
► We describe an efficient approach to generate antiviral single-domain antibodies. ► The activity of initially selected antibodies can be greatly increased by... 
Recombinant antibody formatting | Single-domain antibody | Influenza virus | Passive immunization | HMR-analysis | HEAVY-CHAIN ANTIBODIES | LEUCINE-ZIPPER | HEMAGGLUTININ | RECOGNIZES | FRAGMENTS | VIROLOGY | NANOBODIES | A VIRUSES | PHARMACOLOGY & PHARMACY | COILED-COIL | SELECTION | ANTIGEN RECEPTOR | Humans | Influenza A Virus, H5N2 Subtype - drug effects | Molecular Sequence Data | Influenza A Virus, H5N2 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Camelus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Single-Domain Antibodies - immunology | Camelus - genetics | Female | Influenza, Human - virology | Antibodies, Viral - administration & dosage | Protein Structure, Tertiary | Amino Acid Sequence | Single-Domain Antibodies - administration & dosage | Immunologic Techniques - methods | Animals | Single-Domain Antibodies - chemistry | Antibodies, Viral - chemistry | Antibodies, Viral - immunology | Mice | Mice, Inbred BALB C | Influenza A Virus, H5N2 Subtype - physiology | Single-Domain Antibodies - genetics | Influenza, Human - prevention & control | Antibodies, Viral - genetics | Influenza, Human - immunology | Phosphates | Antiviral agents | Keratin | Enzymes | Analysis | Influenza | Lectins | Avian influenza viruses | Amino acids | Health aspects
Journal Article
Antiviral Research, ISSN 0166-3542, 03/2013, Volume 97, Issue 3, pp. 318 - 328
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1998, Volume 95, Issue 15, pp. 8744 - 8749
The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit... 
Proteins | Complementary DNA | RNA | Reverse transcriptase polymerase chain reaction | Exons | Genes | DNA | Genomics | Mice | Tumors | 3P14.2 | GENE | BIOSYNTHESIS | ENZYMES | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | EXPRESSION | Caenorhabditis elegans | Drosophila | Homology (Biology) | Genetic aspects | Research | Chromosomes | Gene fusion
Journal Article
Science (Washington), ISSN 0036-8075, 11/2001, Volume 294, Issue 5545, pp. 1331 - 1334
In a study, a trithorax acetylation complex that contains Trx, dCBP, and Sbf1 was purified from Drosophila embryos. It was found that Trx, dCBP, and Sbf1 are... 
Journal Article
Science (Washington), ISSN 0036-8075, 11/2001, Volume 294, Issue 5545, pp. 1331 - 1334
In a study, a trithorax acetylation complex that contains Trx, dCBP, and Sbf1 was purified from Drosophila embryos. It was found that Trx, dCBP, and Sbf1 are... 
Journal Article
Journal Article
Mechanisms of Development, ISSN 0925-4773, 1999, Volume 82, Issue 1, pp. 171 - 179
Journal Article