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Biochemical Society Transactions, ISSN 0300-5127, 10/2010, Volume 38, Issue 5, pp. 1220 - 1224
Patients with similar tumour types frequently show different responses to the same therapy. The development of new treatments would benefit, therefore, from... 
Pyruvate | Bicarbonate | Fumarate | Magnetic resonance spectroscopy (MRS) | Cancer | Glutamine | L-Lactate Dehydrogenase - metabolism | Neoplasms - metabolism | Animals | Magnetic Resonance Spectroscopy | Humans | Lactic Acid - metabolism | Pyruvic Acid - metabolism | Carbon Isotopes - analysis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 47, pp. 19801 - 19806
Journal Article
Journal Article
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 09/2019, p. jnumed.119.228692
Journal Article
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 09/2019
A considerable limitation of current small animal positron emission tomography/computed tomography (PET/CT) imaging is the low throughput of image... 
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 04/2019, Volume 25, Issue 8, pp. 2471 - 2482
Purpose: Drug resistance is a major obstacle for the effective treatment of patients with high-grade serous ovarian cancer (HGSOC). Currently, there is no... 
PLASMA | LIPID-PEROXIDATION | CISPLATIN | ONCOLOGY | GLUTATHIONE | ADRIAMYCIN | MECHANISMS | CELL-LINES | CYTOTOXICITY | CARCINOMA | MODULATION | xCT | [18F]FSPG | drug resistance | positron emission tomography | ovarian cancer
Journal Article
Journal Article
THERANOSTICS, ISSN 1838-7640, 2019, Volume 9, Issue 25, pp. 7924 - 7947
Immunotherapy has proven to be an effective approach in a growing number of cancers. Despite durable clinical responses achieved with antibodies targeting... 
T-cells | RADIATION-DOSIMETRY | MEDICINE, RESEARCH & EXPERIMENTAL | SODIUM/IODIDE SYMPORTER | in vivo imaging | DOPAMINE-D-2 RECEPTOR | IN-VIVO TRACKING | PET PROBE | PERFORMANCE EVALUATION | TUMOR-INFILTRATING LYMPHOCYTES | cell-based therapy | Immunotherapy | SODIUM-IODIDE SYMPORTER | CHEMOKINE RECEPTOR | positron emission tomography | REPORTER GENE
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e91694
Tumour response to therapy is assessed primarily in the clinic by monitoring reductions in tumour size. However, this approach lacks sensitivity since in many... 
Non-small cell lung carcinoma | Lung cancer
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 28, pp. 24572 - 24580
Measurements of the kinetics of hyperpolarized (13)C label exchange between [1-(13)C]pyruvate and lactate in suspensions of intact and lysed murine lymphoma... 
Neoplasms - metabolism | Models, Biological | Humans | Lactic Acid - metabolism | Cell Line, Tumor | Pyruvic Acid - metabolism | Kinetics | Carbon Isotopes - chemistry | Tumor Metabolism | NMR | Lactic Acid | PI 3-Kinase | MRI | Pyruvate | Carbon-13 | Enzyme Kinetics | Metabolism | Isotope Exchange
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 02/2018, Volume 15, Issue 1, pp. 55 - 12
Background: The cystine/glutamate antiporter (xc-) has been implicated in several neurological disorders and, specifically, in multiple sclerosis (MS) as a... 
Multiple sclerosis | FSPG | PET | EAE mice | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | OXIDATIVE STRESS | SPINAL-CORD | PATHOLOGY | IMMUNOLOGY | NEUROSCIENCES | PATHOGENESIS | POSITRON-EMISSION-TOMOGRAPHY | INHIBITION | SYSTEM X(C)(-) | Usage | Care and treatment | PET imaging | Development and progression | Research | Diagnosis | Contrast media
Journal Article
Cancer research, 02/2019, Volume 79, Issue 4, p. 853
The cell's endogenous antioxidant system is vital to maintenance of redox homeostasis. Despite its central role in normal and pathophysiology, no noninvasive... 
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 1/2016, Volume 126, Issue 2, pp. 253 - 264
Journal Article