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NATURE CHEMISTRY, ISSN 1755-4330, 10/2019, Volume 11, Issue 10, pp. 913 - 923
Modular polyketide synthases and non-ribosomal peptide synthetases are molecular assembly lines that consist of several multienzyme subunits that undergo... 
DOMAIN | SOLID-STATE NMR | CRYSTAL-STRUCTURE | BIOSYNTHESIS | DYNAMICS | PROTEIN-PROTEIN INTERACTIONS | LIGAND | CHEMISTRY, MULTIDISCIPLINARY | WEB SERVER | PEPTIDE | PREDICTION | Self assembly | Peptides | Chains | Polyketide synthase | Domains | Interfaces | Self-assembly | Antibiotics | Assembling | Docking | Catalysis | Bioinformatics | Assembly lines
Journal Article
Nature Communications, ISSN 2041-1723, 12/2016, Volume 7, Issue 1, p. 13609
Type I modular polyketide synthases assemble diverse bioactive natural products. Such multienzymes typically use malonyl and methylmalonyl-CoA building blocks... 
COENZYME | IDENTIFICATION | ACIDS | BETA-SUBUNIT | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES
Journal Article
Angewandte Chemie, ISSN 0044-8249, 10/2016, Volume 128, Issue 42, pp. 13199 - 13203
In fungal non‐reducing polyketide synthases (NR‐PKS) the acyl‐carrier protein (ACP) carries the growing polyketide intermediate through iterative rounds of... 
Produkttemplatdomäne | Vernetzung | Acylcarrierprotein | Polyketidsynthasen | Physiological aspects | Enzymes | Crosslinked polymers | Product introduction | Protein-protein interactions | Proteins | Residues | Biochemistry | Bioinformatics | Elongation | Recognition | Combinatorial analysis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 50, p. E6844
  Aromatic polyketides make up a large class of natural products with diverse bioactivity. During biosynthesis, linear poly-β-ketone intermediates are... 
Metabolites | Natural products | Biosynthesis | Biological activity
Journal Article
01/2016, ISBN 1369227507
Bacterial, fungal, and plant secondary metabolic pathways afford a huge library of elaborate organic molecules known as natural products. Polyketides and... 
Microbiology | Biochemistry
Dissertation
Angewandte Chemie, ISSN 0044-8249, 10/2016, Volume 128, Issue 42, p. 13199
In fungal non-reducing polyketide synthases (NR-PKS) the acyl-carrier protein (ACP) carries the growing polyketide intermediate through iterative rounds of... 
Enzymes | Biochemical analysis | Crosslinking | Biosynthesis | Fungi | Proteins | Polyketides | Docking | Catalysis | Protein interaction | Bioinformatics | Combinatorial analysis | Elongation
Journal Article
Immunity, ISSN 1074-7613, 05/2019, Volume 50, Issue 5, pp. 1232 - 1248.e14
Journal Article
Immunity, ISSN 1074-7613, 08/2016, Volume 45, Issue 2, pp. 428 - 441
Journal Article
Pediatric Research, ISSN 0031-3998, 06/2014, Volume 75, Issue 6, pp. 689 - 696
Journal Article
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