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1. Full Text Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
by Burton, Paul R and Clayton, David G and Cardon, Lon R and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P and McCarthy, Mark I and Ouwehand, Willem H and Samani, Nilesh J and Todd, John A and Donnelly, Peter and Barrett, Jeffrey C and Davison, Dan and Easton, Doug and Evans, David M and Leung, Hin-Tak and Marchini, Jonathan L and Morris, Andrew P and Spencer, Chris C.A and Tobin, Martin D and Attwood, Antony P and Boorman, James P and Cant, Barbara and Everson, Ursula and Hussey, Judith M and Jolley, Jennifer D and Knight, Alexandra S and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Prowse, Christopher V and Stevens, Helen E and Taylor, Niall C and Walters, Graham R and Walker, Neil M and Watkins, Nicholas A and Winzer, Thilo and Jones, Richard W and McArdle, Wendy L and Ring, Susan M and Strachan, David P and Pembrey, Marcus and Breen, Gerome and Clair, David St and Caesar, Sian and Gordon-Smith, Katharine and Jones, Lisa and Fraser, Christine and Green, Elaine K and Grozeva, Detelina and Hamshere, Marian L and Holmans, Peter A and Jones, Ian R and Kirov, George and Moskivina, Valentina and Nikolov, Ivan and O'Donovan, Michael C and Owen, Michael J and Collier, David A and Elkin, Amanda and Farmer, Anne and Williamson, Richard and McGuffin, Peter and Young, Allan H and Ferrier, I. Nicol and Ball, Stephen G and Balmforth, Anthony J and Barrett, Jennifer H and Bishop, Timothy D and Iles, Mark M and Maqbool, Azhar and Yuldasheva, Nadira and Hall, Alistair S and Braund, Peter S and Dixon, Richard J and Mangino, Massimo and Stevens, Suzanne and Thompson, John R and Bredin, Francesca and Tremelling, Mark and Parkes, Miles and Drummond, Hazel and Lees, Charles W and Nimmo, Elaine R and Satsangi, Jack and Fisher, Sheila A and Forbes, Alastair and Lewis, Cathryn M and Onnie, Clive M and Prescott, Natalie J and Sanderson, Jeremy and Matthew, Christopher G and Barbour, Jamie and Mohiuddin, M. Khalid and Todhunter, Catherine E and Mansfield, John C and Ahmad, Tariq and Cummings, Fraser R and Jewell, Derek P and ... and Breast Cancer Susceptibility Collaboration (UK) and Wellcome Trust Case Control Consortium and Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee and Australo-Anglo-American Spondylitis Consortium (TASC) and The Australo-Anglo-American Spondylitis Consortium (TASC)
Nature Genetics, ISSN 1061-4036, 11/2007, Volume 39, Issue 11, pp. 1329 - 1337
We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing... 
CROHN-DISEASE | GENETIC ASSOCIATION | GENETICS & HEREDITY | GRAVES-DISEASE | SUSCEPTIBILITY LOCI | POPULATION-STRUCTURE | RISK | AMINOPEPTIDASE | ANKYLOSING-SPONDYLITIS | SINGLE-NUCLEOTIDE POLYMORPHISMS | GENOME-WIDE ASSOCIATION | Genetics, Population | Aminopeptidases - genetics | Spondylitis, Ankylosing - genetics | Minor Histocompatibility Antigens | Thyroiditis, Autoimmune - epidemiology | Humans | Autoimmunity - genetics | Genotype | Multiple Sclerosis - genetics | Chromosome Mapping | Multiple Sclerosis - epidemiology | Receptors, Interleukin - genetics | Thyroiditis, Autoimmune - genetics | Case-Control Studies | Linkage Disequilibrium | Haplotypes - genetics | Breast Neoplasms - genetics | Polymerase Chain Reaction | Spondylitis, Ankylosing - epidemiology | Polymorphism, Single Nucleotide - genetics | North America - epidemiology | Receptors, Immunologic - genetics | Breast Neoplasms - epidemiology | Histocompatibility antigens | HLA histocompatibility antigens | Physiological aspects | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Ankylosing spondylitis | Risk factors | Genotype & phenotype | Multiple sclerosis | Genetic research | Genetics | Arthritis | Breast cancer | Autoimmune diseases
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2. Full Text Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
by Speliotes, Elizabeth and Willer, Cristen and Berndt, Sonja and Monda, Keri and Thorleifsson, Gudmar and Jackson, Anne and Allen, H.L and Lindgren, Cecilia and Luan, J and Mägi, Reedik and Randall, Joshua and Vedantam, Sailaja and Winkler, Thomas and Qi, Lu and Workalemahu, Tsegaselassie and Heid, Iris and Steinthorsdottir, Valgerdur and Stringham, Heather and Wheeler, Eleanor and Wood, Anew and Ferreira, Teresa and Weyant, Robert and Segrè, Ayellet and Eestrada, Karol and Liang, Liming and Nemesh, James and Park, J.H and Gustafsson, Stefan and Kilpeläinen, Tuomas and Yang, Joanna and Bouatia-Naji, Nabila and Eesko, Tõnu and Feitosa, Mary Furlan and Kutalik, Zoltán and Mangino, Massimo and Raychaudhuri, Soumya and Scherag, Ane and Smith, Albert Vernon and Welch, Ryan and Zhao, Jing Hua and Aben, Katja and Absher, Devin and Amin, Najaf and Dixon, Anna and Fisher, Eeva and Glazer, Nicole and Goddard, Michael and Heard-Costa, Nancy and Hoesel, Volker and Hottenga, Jouke Jan and Johansson, Åsa and Johnson, Toby and Ketkar, Shamika and Lamina, Claudia and Li, Shengxu and Moffatt, Miriam and Myers, Richard and Narisu, Narisu and Perry, John and Peters, Marjolein and Preuss, Michael and Ripatti, Samuli and Rivadeneira Ramirez, Fernando and Sandholt, Camilla and Scott, Laura and Timpson, Nicholas and Tyrer, Jonathan and Wingerden, Sophie and White, Charles and Wiklund, Freik and Barlassina, Christina and Chasman, Daniel and Cooper, Matthew and Jansson, J.O and Lawrence, Robert and Pellikka, Niina and Prokopenko, Inga and Shi, Jianxin and Thiering, Eelisabeth and Alavere, Helene and Alibrandi, Maria and Almgren, Peter and Arnold, Alice and Aspelund, Thor and Atwood, Larry and Balkau, Beverley and Balmforth, Anthony and Bennett, Amanda and Ben-Shlomo, Y and Bergman, Richard and Bergmann, Sven and Biebermann, Heike and Blakemore, Alexana and Boes, Tanja and Bonnycastle, Lori and Bornstein, Stefan and Brown, Morris and Buchanan, Thomas and Busonero, F and Campbell, Harry and ... and MAGIC and Procardis Consortium and on behalf of Procardis Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 11/2010, Volume 42, Issue 11, pp. 937 - 948
textabstractObesity is globaLy prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity... 
COMMON VARIANTS | OBESITY | METAANALYSIS | FTO GENE | GLUCOSE | GENETICS & HEREDITY | EARLY-ONSET | GASTRIC-INHIBITORY POLYPEPTIDE | WEIGHT | FAT MASS | GENOME-WIDE ASSOCIATION | Body Mass Index | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Body Size - genetics | Chromosome Mapping | Polymorphism, Single Nucleotide | Body Weight - genetics | Obesity - genetics | Body Height - genetics | Measurement | Body mass index | Obesity | Genetic aspects | Research | Risk factors | Studies | Medical research | Hospitals | Biomedical research | Councils | Risk assessment | Genetics | Charitable foundations | Public health | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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3. Full Text Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
by Heid, Iris and Jackson, Anne and Randall, Joshua and Winkler, Thomas and Qi, Lu and Ssteinthorsdottir, Valgerdur and Tthorleifsson, Ggudmar and Zillikens, Carola and Sspeliotes, Eelizabeth and Mägi, Reedik and Workalemahu, Tsegaselassie and White, Charles and Bouatia-Naji, Nabila and Harris, Tamara and Berndt, Sonja and Ingelsson, Erik and Willer, Cristen and Luan, J and Vedantam, Sailaja and Eesko, Tõnu and Kilpeläinen, Tuomas and Kutalik, Zoltán and Li, Shengxu and Monda, Keri and Dixon, Anna and Holmes, Christopher and Kaplan, Robert and Liang, Liming and Min, Josine and Moffatt, Miriam and Molony, Cliona and Nicholson, Ggeorge and Sschadt, Eeric and Zondervan, Krina and Feitosa, Mary Furlan and Ferreira, Teresa and Allen, H.L and Weyant, Robert and Wheeler, Eleanor and Wood, Anew and Eestrada, Karol and Goddard, Michael and Lettre, Guillaume and Mangino, Massimo and Nyholt, Dale and Purcell, Shaun and Ssmith, A.V and Visscher, Peter and Yang, Joanna and McCcarroll, Ssteven and Nemesh, James and Voight, Benjamin and Absher, Devin and Amin, Najaf and Aspelund, Thor and Coin, Lachlan and Glazer, Nicole and Hayward, Caroline and Heard-Ccosta, Nancy and Hottenga, Jouke Jan and Johansson, Åsa and Johnson, Toby and Kaakinen, Marika and Kapur, Karen and Ketkar, Shamika and Knowles, Joshua and Kraft, Peter and Kraja, Aldi and Lamina, Claudia and Leitzmann, Michael and McKknight, Barbara and Morris, Anew and Oong, Ken and Perry, John and Peters, Marjolein and Polasek, Ozren and Prokopenko, Inga and Rayner, Nigel William and Ripatti, Samuli and Rivadeneira Ramirez, Fernando and Robertson, Neil and Sanna, Serena and Sovio, Ulla and Surakka, Ida and Teumer, Alexander and Wingerden, Sophie and Vitart, Veronique and Zhao, Jing Hua and Cavalcanti-Proença, Christine and Chines, Peter and Fisher, Eeva and Kulzer, Jennifer and Lecoeur, Cécile and Narisu, Narisu and Sandholt, Camilla and Scott, Laura and Silander, Kaisa and Stark, Klaus and Tammesoo, M.L and Teslovich, Tanya and ... and MAGIC and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Molekylär medicin and Genomik and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature Genetics, ISSN 1061-4036, 11/2010, Volume 42, Issue 11, pp. 949 - 960
textabstractWaist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is... 
BODY-FAT | COMMON VARIANTS | GLUCOSE-HOMEOSTASIS | ABDOMINAL ADIPOSITY | OBESITY | INSULIN-RESISTANCE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | RISK | CORONARY-HEART-DISEASE | GENOME-WIDE ASSOCIATION | Genome-Wide Association Study | Meta-Analysis as Topic | Age Factors | Humans | Female | Male | Chromosome Mapping | Polymorphism, Single Nucleotide | Sex Characteristics | Genome, Human | Waist-Hip Ratio | Adipose Tissue - anatomy & histology | Measurement | Body mass index | Genetic aspects | Dimorphism (Biology) | Research | Gene loci | Diabetes | Body fat | Meta-analysis | body composition | genetics | sex difference | body fat distribution | central obesity | meta-analysis | Expression Quantitative Trait Loci | metabolism | genome-wide association | waist-hip-ratio | visceral adipose tissue | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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4. Full Text Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
by Willer, Cristen and Speliotes, Elizabeth and Loos, Ruth and Li, Shengxu and Lindgren, Cecilia and Heid, Iris and Berndt, Sonja and Elliott, Amanda and Jackson, Anne and Lamina, Claudia and Lettre, Guillaume and Lim, Noha and Lyon, Helen and McCarroll, Steven and Papadakis, Konstantinos and Qi, Lu and Randall, Joshua and Roccasecca, R.M and Sanna, Serena and Scheet, Paul and Weedon, Michael and Wheeler, Eleanor and Zhao, Jing Hua and Jacobs, Leonie and Prokopenko, Inga and Soranzo, Nicole and Tanaka, Toshiko and Timpson, Nicholas and Almgren, Peter and Bennett, Amanda and Bergman, Richard and Bingham, Sheila and Bonnycastle, Lori and Brown, Morris and Burtt, Noël and Chines, Peter and Coin, Lachlan and Collins, Francis and Connell, John and Cooper, Charles and Smith, Davey and Dennison, Elaine and Deodhar, Parimal and Erdos, Michael and Estrada Gil, Karol and Evans, David and Gianniny, Lauren and Gieger, Christian and Gillson, Christopher and Guiducci, Candace and Hackett, Rachel and Hadley, David and Hall, Alistair and Havulinna, Aki and Hebebrand, Johannes and Hofman, Albert and Isomaa, Bo and Johnson, Toby and Jousilahti, Pekka and Jovanovic, Zorica and Khaw, Kay-Tee and Kraft, Peter and Kuokkanen, Mikko and Kuusisto, Johanna and Laitinen, Jaana and Lakatta, Edward and Luan, J and Luben, Robert and Mangino, Massimo and McArdle, Wendy and Meitinger, Thomas and Mulas, Antonella and Munroe, Patricia and Narisu, Narisu and Ness, Anew and Northstone, Kate and O'Rahilly, Stephen and Purmann, Carolin and Rees, Matthew and Ridderstråle, Martin and Ring, Susan and Rivadeneira Ramirez, Fernando and Ruokonen, Aimo and Sandhu, Manjinder and Saramies, Jouko and Scott, Laura and Scuteri, Angelo and Silander, Kaisa and Sims, Matthew and Song, Kijoung and Stephens, Jonathan and Stevens, Suzanne and Stringham, Heather and Tung, Loraine and Valle, Timo and Tikka-Kleemola, Päivi and Vimaleswaran, Karani and Vollenweider, Peter and Waeber, Gérard and Wallace, Chris and ... and Wellcome Trust Case Control and Giant Consortium and Wellcome Trust Case Control Consortium and Genetic Investigation of ANthropometric Traits Consortium and the GIANT Consortium and Diabetes - klinisk obesitasforskning and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Diabetes - Clinical Obesity and Lunds universitet
Nature Genetics, ISSN 1061-4036, 01/2009, Volume 41, Issue 1, pp. 25 - 34
textabstractCommon variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional... 
COMMON VARIANTS | FTO GENE | NEURITE OUTGROWTH | GENETICS & HEREDITY | MICE | CHILDHOOD OBESITY | ADULT OBESITY | EXPRESSION | CORONARY-ARTERY-DISEASE | ALCOHOL DEPENDENCE | GENOME-WIDE ASSOCIATION | Body Mass Index | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Quantitative Trait, Heritable | Obesity - complications | Anthropometry | Humans | Gene Dosage | Body Weight - genetics | Obesity - genetics | Central Nervous System - physiology | Alleles | Polymorphism, Single Nucleotide - genetics | Cohort Studies | Quantitative Trait Loci - genetics | Body mass index | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Body weight | Medical research | Biomedical research | Neurons | Mortality | Genetics | Life sciences | Weight | Cancer | Meta-analysis | Clinical Medicine | Näringslära | Hälsovetenskap | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Nutrition and Dietetics | Endocrinology and Diabetes | Health Sciences
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5. Full Text Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
by Dastani, Zari and Hivert, Marie-France and Timpson, Nicholas and Perry, John R. B and Yuan, Xin and Scott, Robert A and Henneman, Peter and Heid, Iris M and Kizer, Jorge R and Lyytikäinen, Leo-Pekka and Fuchsberger, Christian and Tanaka, Toshiko and Morris, Anew P and Small, Kerrin and Isaacs, Aaron and Beekman, Marian and Coassin, Stefan and Lohman, Kurt and Qi, Lu and Kanoni, Stavroula and Pankow, James S and Uh, Hae-Won and Wu, Ying and Bidulescu, Aurelian and Rasmussen-Torvik, Laura J and Greenwood, Celia M. T and Ladouceur, Martin and Grimsby, Jonna and Manning, Alisa K and Liu, Ching-Ti and Kooner, Jaspal and Mooser, Vincent E and Vollenweider, Peter and Kapur, Karen A and Chambers, John and Wareham, Nicholas J and Langenberg, Claudia and Frants, Rune and Willems-Vandijk, Ko and Oostra, Ben A and Willems, Sara M and Lamina, Claudia and Winkler, Thomas W and Psaty, Bruce M and Tracy, Russell P and Brody, Jennifer and Fouchier, Sigrid W and Hovingh, G. Kees and Boekholdt, S. Matthijs and Kastelein, John J. P and GLGC Investigators and DIAGRAM Consortium and MAGIC Consortium and MuTHER Consortium and Global B Pgen Consortium and MAGIC investigators and Procardis Consortium and DIAGRAM+ Consortium and GLGC Consortium and GIANT Consortium
PLoS genetics, ISSN 1553-7390, 2012, Volume 8, Issue 3, p. e1002607
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes... 
POPULATION | GENETIC-BASIS | VARIANTS | INSULIN-RESISTANCE | LIPID CONCENTRATIONS | GENETICS & HEREDITY | RISK | RECEPTOR | CORONARY-ARTERY-DISEASE | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Gene Expression | Genetic Predisposition to Disease | Genome-Wide Association Study | Glucose Tolerance Test | Diabetes Mellitus, Type 2 - genetics | Humans | African Americans | European Continental Ancestry Group | Male | Cholesterol, HDL - genetics | Adiponectin - blood | Asian Continental Ancestry Group | Metabolic Networks and Pathways | Adiponectin - genetics | Insulin Resistance - genetics | Female | Polymorphism, Single Nucleotide | Waist-Hip Ratio | Type 2 diabetes | Physiological aspects | Development and progression | Genetic aspects | Research | Metabolism | Health aspects | Blood proteins | Meta-analysis | Medical research | Cardiovascular disease | Drug therapy | Insulin | Metabolic disorders | Medical and Health Sciences | Medicin och hälsovetenskap
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