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Expert Opinion on Investigational Drugs, ISSN 1354-3784, 08/2012, Volume 21, Issue 8, pp. 1141 - 1154
Introduction: The treatment options for patients with myelofibrosis (MF) remain limited. Anemia, thrombocytopenia, extramedullary hematopoiesis, constitutional... 
Thrombocytopenia | Splenomegaly | Myelofibrosis | Anemia | Immunomodulation | Mortality | biomarkers | Data processing | Morbidity | Hemopoiesis | Reviews | Janus kinase 2 | Thalidomide
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 4600 - 4600
Abstract Myelodysplastic syndromes (MDS) encompass a clinically and pathologically heterogeneous group of blood cancers characterized by dysplasia, cytopenias,... 
Journal Article
Nitric Oxide, ISSN 1089-8603, 11/2014, Volume 42, pp. 146 - 146
Journal Article
Nitric Oxide, ISSN 1089-8603, 11/2014, Volume 42, p. 146
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 4063 - 4063
Abstract Myelofibrosis (MF), a Philadelphia chromosome negative myeloproliferative neoplasm (MPN) requires clonal markers for accurate diagnosis according to... 
Journal Article
Blood, ISSN 0006-4971, 04/2012, Volume 119, Issue 14, pp. 3203 - 3210
Journal Article
British Journal of Haematology, ISSN 0007-1048, 04/2012, Volume 157, Issue 2, pp. 266 - 267
Journal Article
Leukemia Research, ISSN 0145-2126, 06/2013, Volume 37, Issue 6, pp. 609 - 613
Treatment of CMML remains a clinical challenge, with no drug demonstrating clear clinical benefit. Even if azacitidine is approved in the treatment of CMML,... 
Journal Article
Journal Article
Journal Article
Therapeutic Advances in Hematology, ISSN 2040-6207, 08/2014, Volume 5, Issue 4, pp. 107 - 120
Journal Article
Blood, ISSN 0006-4971, 10/2012, Volume 120, Issue 16, pp. 3173 - 3186
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 462 - 462
Abstract Abstract 462 In myelodysplastic syndrome (MDS), mutations in genes affecting epigenetic regulation constitute a link between genomic and epigenetic... 
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2018, Volume 24, Issue 9, pp. 2082 - 2091
Purpose: The purpose of this study was to determine a recommended phase II dose and schedule of LY2940680 (taladegib) for safe administration to patients with... 
TRIAL | MULTICENTER | ADVANCED SOLID TUMORS | VISMODEGIB | ONCOLOGY | HEDGEHOG PATHWAY INHIBITOR | SONIDEGIB LDE225 | OPEN-LABEL | MECHANISMS | Slopes | Therapy | Toxicity | Muscles | Fatigue | Nausea | Pharmacology | mRNA | Metastasis | Patients | Biological activity | Metastases | Spasms | Confidence intervals | Experimental design | Hedgehog protein | Safety engineering | Skin | Cancer
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 21, pp. 1687 - 1687
Abstract Abstract 1687 Genetic alterations including chromosomal translocation, somatic mutation, and gene amplification are thought to play a key role in... 
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e43090
Journal Article