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Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7562, pp. 607 - 611
The human lens is comprised largely of crystallin proteins assembled into a highly ordered, interactive macro-structure essential for lens transparency and... 
SELENITE-INDUCED CATARACTOGENESIS | MULTIDISCIPLINARY SCIENCES | MUTATION | PREVENTION | ALPHA-B-CRYSTALLIN | DOMINANT CONGENITAL CATARACT | HUMAN OXIDOSQUALENE CYCLASE | SEQUENCING DATA | CHINESE FAMILY | LENS | EXPRESSION | Crystallins - metabolism | Humans | Cataract - pathology | Molecular Sequence Data | Lanosterol - pharmacology | Male | Amyloid - chemistry | Amyloid - ultrastructure | Lens, Crystalline - pathology | Mutant Proteins - ultrastructure | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Base Sequence | Amyloid - drug effects | Adult | Female | Child | Crystallins - chemistry | Protein Aggregates - drug effects | Amino Acid Sequence | Cell Line | Crystallins - ultrastructure | Lanosterol - administration & dosage | Mutant Proteins - genetics | Lens, Crystalline - metabolism | Models, Molecular | Mutant Proteins - metabolism | Crystallins - genetics | Cataract - metabolism | Lanosterol - therapeutic use | Protein Aggregation, Pathological - drug therapy | Animals | Cataract - congenital | Pedigree | Mutant Proteins - chemistry | Dogs | Cataract - genetics | Cataract - drug therapy | Lens, Crystalline - drug effects | Proteins | Cataract | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Drug therapy | Cataracts | Studies | Older people | Mortality | Mutation | Cholesterol | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2016, Volume 473, Issue 1, p. 1
Vertebrate lens is one of the tissues with the highest soluble protein concentration. The predominant soluble proteins in lens fiber cells are crystallins, and... 
Proteins | Heat shock proteins | Cataract | Oligomers | Albumin | Protein binding
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 11/2014, Volume 1842, Issue 11, p. 2216
Disease-causing mutations can be stabilizing or destabilizing. Missense mutations of structural residues are generally destabilizing, while stabilizing... 
Proteins | Cataract | Analysis | Denaturation | Genetic aspects | Hydrogen-ion concentration
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 11/2014, Volume 1842, Issue 11, pp. 2216 - 2229
Journal Article
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