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Current allergy and asthma reports, 09/2017, Volume 17, Issue 10, p. 72
To limit excessive T cell-mediated inflammatory responses, the immune system has a milieu of inhibitory receptors, called immune checkpoints. Cancer cells have... 
Autoimmunity - immunology | Neoplasms - immunology | Humans | Immunotherapy | T-Lymphocytes - immunology | Cell Cycle Checkpoints - immunology
Journal Article
Current Allergy and Asthma Reports, ISSN 1529-7322, 10/2017, Volume 17, Issue 10, pp. 1 - 9
To limit excessive T cell-mediated inflammatory responses, the immune system has a milieu of inhibitory receptors, called immune checkpoints. Cancer cells have... 
Allergology | Autoimmunity | Checkpoint inhibitors | Medicine & Public Health | Tolerance | Immune checkpoints | T cells | Cancer | TYROSINE PHOSPHORYLATION | TISSUE | ACQUIRED-RESISTANCE | IMMUNOLOGY | IG-LIKE RECEPTOR-1 | B-LYMPHOCYTE | POLYMORPHISMS | ALLERGY | REGULATORY T-CELLS | CTLA-4 | PD-1 | ASSOCIATION | Viral antibodies | Antibodies | Medical colleges
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2019, p. jbc.AC119.011747
Programmed cell death protein 1 (PD-1) is an inhibitory receptor on T lymphocytes that is critical for modulating adaptive immunity. As such, it has been... 
Journal Article
Vaccine, ISSN 0264-410X, 2015, Volume 33, Issue 17, pp. 2015 - 2021
Highlights • PCV7 serotype replacement was near complete 5 years after PCV7 introduction. • The carriage rate remained stable through out the 5 year period. •... 
Allergy and Immunology | Serotype replacement | Pneumococcal vaccines | Whole genome | Next generation sequencing | Streptococcus pneumoniae | MEDICINE, RESEARCH & EXPERIMENTAL | CONJUGATE VACCINATION | IMMUNOLOGY | NASOPHARYNGEAL CARRIAGE | CHILDREN | STREPTOCOCCUS-PNEUMONIAE | EVOLUTION | CLONES | VACCINES | Heptavalent Pneumococcal Conjugate Vaccine - immunology | Streptococcus pneumoniae - classification | Humans | Carrier State - microbiology | Child, Preschool | Infant | Male | Pneumococcal Vaccines - administration & dosage | Streptococcus pneumoniae - immunology | Vaccines, Conjugate - immunology | Pneumococcal Infections - immunology | Streptococcus pneumoniae - isolation & purification | Time Factors | Streptococcus pneumoniae - genetics | Female | Pneumococcal Infections - microbiology | Seasons | Nasopharynx - microbiology | Serotyping | Heptavalent Pneumococcal Conjugate Vaccine - administration & dosage | Genome, Bacterial | Serogroup | Genotype | United Kingdom | Sequence Analysis, DNA | Vaccines, Conjugate - administration & dosage | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - immunology | High-Throughput Nucleotide Sequencing | Confidence intervals | Medical research | Pneumonia | Hospitals | Biomedical research | Surveillance | Genomes | Vaccines | Public health | Age | Children & youth | Streptococcus infections
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2018, Volume 201, Issue 9, pp. 2812 - 2823
Programmed cell death 1 (PD-1) is a major coinhibitory receptor and a member of the immunological synapse (IS). To uncover proteins that regulate PD-1... 
IMMUNORECEPTOR | RESPONSES | ACTIVATION | ACTIN | PHOSPHORYLATION | MOLECULE | B7 FAMILY | RECEPTOR | SWIPROSIN-1 | SECRETION | IMMUNOLOGY
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2017, Volume 114, Issue 51, pp. E10956 - E10964
Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a major human pandemic. Germline-encoded mycolyl lipid-reactive (GEM) T cells are... 
Molecular dynamics | GEM T cells | Mycolate lipids | Mycobacterium tuberculosis | CD1b | REPERTOIRE | RECOGNITION | PROTECTION | MULTIDISCIPLINARY SCIENCES | HUMAN CD1B | ALPHA | ANTIGENS | molecular dynamics | mycolate lipids | FINE SPECIFICITY | ESTERS | INFECTION | METHOXY | Physiological aspects | Lipids | T cells | Biological Sciences | Physical Sciences | PNAS Plus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 3, pp. E468 - E477
Programmed cell death-1 (PD-1) is an essential inhibitory receptor in T cells. Antibodies targeting PD-1 elicit durable clinical responses in patients with... 
SHP2 | SAP | T cells | PD-1 | XLP | ACTIVATION | PROGRAMMED DEATH-1 | MULTIDISCIPLINARY SCIENCES | SH2 DOMAINS | CELL COSTIMULATORY RECEPTOR | B7 FAMILY | LIGAND | PROTEOMIC ANALYSIS | T-CELLS | EGF RECEPTOR | PKC-THETA | Physiological aspects | Observations | Cell death | Mass spectrometry | Methods | Biological Sciences | PNAS Plus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 3, p. E468
Programmed cell death-1 (PD-1) is an essential inhibitory receptor in T cells. Antibodies targeting PD-1 elicit durable clinical responses in patients with... 
PD-1 protein | Protein purification | Antibodies | Lymphocytes T | SAP protein | Proteins | Cell activation | Molecular shields | Lymphocytes | Tyrosine | Spectroscopy | Immunoglobulins | Purification | Mass spectroscopy | T cell receptors | Patients | Cells | Signaling | Inhibitors | Immune checkpoint | Cell death | Biomarkers | Affinity | Mass spectrometry | Tumors | Protein-tyrosine-phosphatase | Apoptosis
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0163889
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 26, pp. 4400 - 4404
Journal Article
Vaccine, ISSN 0264-410X, 06/2013, Volume 31, Issue 31, pp. 3187 - 3190
The success of Streptococcus pneumoniae (pneumococcus) in both colonisation and disease is associated with the increased prevalence of genetic clones... 
Age
Journal Article
18.