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Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2008, Volume 118, Issue 5, pp. 1739 - 1749
Journal Article
Nature Communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 11491
Journal Article
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2015, Volume 17, Issue 8, pp. 1074 - 1087
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-genome siRNA-based reverse genetics... 
JOUBERT-SYNDROME | RPGRIP1 | TRANSPORT | CENTRIOLE BIOGENESIS | PROTEIN | C-ELEGANS | MUTATIONS | PHOTORECEPTOR CELLS | MASTER REGULATOR | PRIMARY CILIA | CELL BIOLOGY | Humans | Pregnancy Proteins - genetics | Databases, Genetic | Suppressor Factors, Immunologic - genetics | Photoreceptor Cells - ultrastructure | Pregnancy Proteins - metabolism | Ellis-Van Creveld Syndrome - genetics | Cerebellum - abnormalities | Genetic Testing - methods | Suppressor Factors, Immunologic - metabolism | Membrane Proteins - deficiency | Transfection | RNA Interference | HEK293 Cells | Kidney Diseases, Cystic - genetics | Genomics - methods | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Caenorhabditis elegans - metabolism | Cilia - pathology | Caenorhabditis elegans - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Abnormalities, Multiple | Genetic Markers | Eye Abnormalities - genetics | Cilia - metabolism | Zebrafish - genetics | Cilia - genetics | Mice, Knockout | Proteins - genetics | Caenorhabditis elegans - ultrastructure | Phenotype | Animals | Cerebellar Diseases - genetics | Ciliary Motility Disorders - pathology | Proteins - metabolism | Photoreceptor Cells - metabolism | Zebrafish - metabolism | Retina - abnormalities | High-Throughput Nucleotide Sequencing | Ciliary Motility Disorders - metabolism | Mutation | Ciliary Motility Disorders - genetics | RNA | Cilia and ciliary motion | Genetic research | Biosynthesis | Genetic aspects | Research | Gene expression | Properties | reverse genetics | cilia | ciliopathies | Joubert syndrome | whole-genome siRNA screen | Jeune syndrome
Journal Article
Journal Article
Haematologica, ISSN 0390-6078, 03/2011, Volume 96, Issue 3, pp. 408 - 416
Background Chronic lymphocytic leukemia cells show prolonged survival in vivo, but rapidly die by spontaneous apoptosis in vitro, unless they are co-cultured... 
CCL2 | Chronic lymphocytic leukemia | Cell survival | NRF2 | TREM1 | APOPTOSIS | ACTIVATION | cell survival | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | PROLIFERATION | CANCER | chronic lymphocytic leukemia | GENES | RECEPTORS | HEMATOLOGY | CLL B-CELLS | EXPRESSION | MARROW STROMAL CELLS | Leukocytes, Mononuclear - metabolism | Membrane Glycoproteins - metabolism | Cell Count | Coculture Techniques | Humans | Oxidative Stress - immunology | Tumor Microenvironment | Apoptosis - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Case-Control Studies | Inflammation - metabolism | Chemokine CCL2 - metabolism | Cell Culture Techniques | Cytokines - immunology | Gene Expression | Cytokines - metabolism | Cell Survival | Stromal Cells - metabolism | Oxidative Stress - genetics | Cell Communication | Chemokine CCL2 - genetics | Signal Transduction - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | GA-Binding Protein Transcription Factor - genetics | Membrane Glycoproteins - genetics | Leukocytes, Mononuclear - pathology | Apoptosis - immunology | Triggering Receptor Expressed on Myeloid Cells-1 | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Protein Array Analysis | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Stromal Cells - cytology | Culture Media, Conditioned - metabolism | GA-Binding Protein Transcription Factor - metabolism | Original
Journal Article
Bioinformatics, ISSN 1367-4803, 7/2009, Volume 25, Issue 13, pp. 1711 - 1712
Journal Article
Molecular bioSystems, ISSN 1742-206X, 01/2012, Volume 8, Issue 1, pp. 268 - 281
Traditionally, protein-protein interactions were thought to be mediated by large, structured domains. However, it has become clear that the interactome... 
Protein Structure, Tertiary | Humans | Protein Folding | Amino Acid Motifs | Amino Acids - metabolism | Repetitive Sequences, Amino Acid | Sequence Alignment | Animals | Proteins - metabolism | Databases, Protein | Conserved Sequence | Hydrophobic and Hydrophilic Interactions | Proteins - chemistry | Evolution, Molecular
Journal Article
PLoS One, ISSN 1932-6203, 2019, Volume 14, Issue 5, p. e0216705
Journal Article