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1. Full Text CD8+ T cells: mechanistic target of rapamycin and eukaryotic initiation factor 2 in elite HIV-1 control
by Nyanhete, Tinashe and Tomaras, Georgia D
AIDS, ISSN 0269-9370, 11/2018, Volume 32, Issue 18, pp. 2835 - 2838
INFECTIOUS DISEASES | ACTIVATION | AVIDITY | VIVO | IMMUNODEFICIENCY-VIRUS-INFECTION | POLYFUNCTIONALITY | PROLIFERATION | IMMUNOLOGY | MTOR | mechanistic targets of rapamycin | VIROLOGY | HIV | MEMORY | METABOLISM | IMMUNE-RESPONSES | elite controller | elF2 | CD8-Positive T-Lymphocytes | HIV Infections | HIV-1 | Metabolic Networks and Pathways | Sirolimus | Humans | Eukaryotic Initiation Factor-2
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2. HIV-1/SIV Humoral Responses in External Secretions
by Mestecky, Jiri and Tomaras, Georgia D
Current Immunology Reviews, ISSN 1573-3955, 04/2019, Volume 15, Issue 1, p. 49
The protective function of mucosal HIV-1- or SIV-specific antibodies against viral infection has stimulated extensive studies of their Ig isotype association... 
Antigens | Immunoglobulins | Isotypes | Proteolysis | Immunoglobulin G | Mucosa | Human immunodeficiency virus--HIV | Inflammation | Secretions | Immunoglobulin A | Viral infections | Binding sites
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3. Full Text E103 HIV-1 Vaccine Elicited IgA and IgG Antibody Specificities
by Tomaras, Georgia D
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2013, Volume 62, p. S52
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4. Full Text Methods for comparing durability of immune responses between vaccine regimens in early-phase trials
by Westling, Ted and Juraska, Michal and Seaton, Kelly E and Tomaras, Georgia D and Gilbert, Peter B and Janes, Holly
Statistical Methods in Medical Research, ISSN 0962-2802, 2019, p. 96228021882088
nonlinear model | vaccine trials | immune response | Area under the curve | generalized estimating equations
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5. Full Text Complex immune correlates of protection in HIV‐1 vaccine efficacy trials
by Tomaras, Georgia D and Plotkin, Stanley A
Immunological Reviews, ISSN 0105-2896, 01/2017, Volume 275, Issue 1, pp. 245 - 261
Summary Development of an efficacious HIV‐1 vaccine is a major priority for improving human health worldwide. Vaccine‐mediated protection against human... 
correlates of protection | HIV | cellular | sieve analysis | antibodies | immunity | humoral | complex immune correlate | correlate of decreased HIV‐1 risk | vaccination | correlate of decreased HIV-1 risk | TEST-OF-CONCEPT | HEMAGGLUTINATION-INHIBITING ANTIBODY | LINKED-IMMUNOSORBENT-ASSAY | CELL-MEDIATED-IMMUNITY | HUMAN MONOCLONAL-ANTIBODY | CD4(+) T-CELLS | IMMUNOLOGY | BROADLY NEUTRALIZING ANTIBODIES | VARICELLA-ZOSTER-VIRUS | IMMUNODEFICIENCY-VIRUS TYPE-1 | TERM-FOLLOW-UP | HIV Infections - immunology | HIV Infections - prevention & control | HIV-1 - immunology | Animals | Humans | AIDS Vaccines - immunology | HIV Infections - transmission | Risk | Clinical Trials as Topic | Disease Models, Animal | Prevention | Clinical trials | AIDS vaccines | HIV (Viruses) | Analysis | Vaccination | Pathogens | Disease transmission | Immunology | Effectiveness | Immune response | Correlation analysis | Human immunodeficiency virus--HIV | Health risks | Infections | Vaccines
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6. Full Text Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
by Mattia Bonsignori and Justin Pollara and M. Anthony Moody and Michael D. Alpert and Xi Chen and Kwan-Ki Hwang and Peter B. Gilbert and Ying Huang and Thaddeus C. Gurley and Daniel M. Kozink and Dawn J. Marshall and John F. Whitesides and Chun-Yen Tsao and Jaranit Kaewkungwal and Sorachai Nitayaphan and Punnee Pitisuttithum and Supachai Rerks-Ngarm and Jerome H. Kim and Nelson L. Michael and Georgia D. Tomaras and David C. Montefiori and George K. Lewis and Anthony DeVico and David T. Evans and Guido Ferrari and Hua-Xin Liao and Barton F. Haynes
Journal of Virology, ISSN 0022-538X, 11/2012, Volume 86, Issue 21, pp. 11521 - 11532
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
RESPONSES | VIROLOGY | RHESUS-MONKEYS | IMMUNODEFICIENCY-VIRUS TYPE-1 | SHIV CHALLENGE | INFLUENZA-VIRUS | GP120 | HUMAN MONOCLONAL-ANTIBODIES | ADCC | RECEPTOR-BINDING | NEUTRALIZING-ANTIBODY | Genes, Immunoglobulin Heavy Chain | HIV-1 - immunology | Antibody-Dependent Cell Cytotoxicity | HIV Antibodies - immunology | Humans | AIDS Vaccines - immunology | Female | Male | AIDS Vaccines - administration & dosage | Human Experimentation | Vaccines and Antiviral Agents
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7. CXCL13 is a plasma biomarker of germinal center activity
by Colin Havenar-Daughton and Madelene Lindqvist and Antje Heit and Jennifer E Wu and Samantha M Reiss and Kayla Kendric and Simon Bélanger and Sudhir Pai Kasturi and Elise Landais and Rama S Akondy and Helen M McGuire and Marcella Bothwell and Parsia A Vagefi and Eileen Scully and Georgia D Tomaras and Mark M Davis and Pascal Poignard and Rafi Ahmed and Bruce D Walker and Bali Pulendran and M Juliana McElrath and Daniel E Kaufmann and Shane Crotty
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2016, Volume 113, Issue 10, p. 2702
  Significantly higher levels of plasma CXCL13 [chemokine (C-X-C motif) ligand 13] were associated with the generation of broadly neutralizing antibodies... 
Plasma | Immunoglobulins | Immunization | Immunology | Human immunodeficiency virus--HIV | Biomarkers | T cell receptors
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8. Full Text The immune response during acute HIV-1 infection: clues for vaccine development
by McMichael, Andrew J and Haynes, Barton F and Goonetilleke, Nilu and Tomaras, Georgia D and Borrow, Persephone
Nature Reviews Immunology, ISSN 1474-1733, 01/2010, Volume 10, Issue 1, pp. 11 - 23
The early immune response to HIV-1 infection is likely to be an important factor in determining the clinical course of disease. Recent data indicate that the... 
PLASMACYTOID DENDRITIC CELLS | NATURAL-KILLER-CELLS | VIRAL SET-POINT | T-CELL RESPONSES | ACTIVE ANTIRETROVIRAL THERAPY | IN-VIVO | SUBTYPE-C INFECTION | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | TYPE-1 INFECTION | DISEASE PROGRESSION | HIV Infections - immunology | HIV-1 - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Animals | Simian Acquired Immunodeficiency Syndrome - immunology | HIV Infections - genetics | HIV Infections - virology | Humans | AIDS Vaccines - immunology | Macaca | HIV-1 - genetics | Simian Immunodeficiency Virus - immunology | Infection | Immune response | Viremia | Mucosa | Data processing | Kinetics | Mutation | Vaccines
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9. Full Text Innate activation of MDC and NK cells in high-risk HIV-exposed seronegative IV-drug users who share needles when compared with low-risk nonsharing IV-drug user controls
by Tomescu, Costin and Seaton, Kelly E and Smith, Peter and Taylor, Mack and Tomaras, Georgia D and Metzger, David S and Montaner, Luis J
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 03/2015, Volume 68, Issue 3, pp. 264 - 273
HIV/AIDS | HESN | intravenous drug users | NK cells | dendritic cells
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10. Full Text Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2
by Liao, Hua-Xin and Bonsignori, Mattia and Alam, S. Munir and McLellan, Jason S and Tomaras, Georgia D and Moody, M. Anthony and Kozink, Daniel M and Hwang, Kwan-Ki and Chen, Xi and Tsao, Chun-Yen and Liu, Pinghuang and Lu, Xiaozhi and Parks, Robert J and Montefiori, David C and Ferrari, Guido and Pollara, Justin and Rao, Mangala and Peachman, Kristina K and Santra, Sampa and Letvin, Norman L and Karasavvas, Nicos and Yang, Zhi-Yong and Dai, Kaifan and Pancera, Marie and Gorman, Jason and Wiehe, Kevin and Nicely, Nathan I and Rerks-Ngarm, Supachai and Nitayaphan, Sorachai and Kaewkungwal, Jaranit and Pitisuttithum, Punnee and Tartaglia, James and Sinangil, Faruk and Kim, Jerome H and Michael, Nelson L and Kepler, Thomas B and Kwong, Peter D and Mascola, John R and Nabel, Gary J and Pinter, Abraham and Zolla-Pazner, Susan and Haynes, Barton F
Immunity, ISSN 1074-7613, 01/2013, Volume 38, Issue 1, pp. 176 - 186
The RV144 HIV-1 trial of the canary pox vector (ALVAC-HIV) plus the gp120 AIDSVAX B/E vaccine demonstrated an estimated efficacy of 31%, which correlated... 
V1/V2 DOMAIN | NEUTRALIZING ANTIBODIES | EFFICACY TRIAL | GP41 | IMMUNODEFICIENCY-VIRUS TYPE-1 | REACTIVITY | INFECTION | GP120 | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | EPITOPES | HIV Antibodies - metabolism | Amino Acid Sequence | Peptides - chemistry | Humans | Peptides - immunology | AIDS Vaccines - immunology | Amino Acid Substitution - immunology | Molecular Sequence Data | Protein Binding - immunology | HIV Antibodies - chemistry | HIV Envelope Protein gp120 - metabolism | HIV Envelope Protein gp120 - immunology | Peptides - metabolism | HIV Antibodies - immunology | Protein Conformation | Molecular Docking Simulation | Antibodies, Monoclonal - metabolism | HIV Envelope Protein gp120 - chemistry | Antibodies, Monoclonal - immunology | Medical colleges | Analysis | Crystals | Monoclonal antibodies | Vaccines | T cells | HIV (Viruses) | Structure | Public health | Biopharmaceutics | Medical informatics | Proteins | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Viruses | Ligands | Infections | Binding sites
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11. Full Text Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
by Haynes, Barton F and Gilbert, Peter B and McElrath, M. Juliana and Zolla-Pazner, Susan and Tomaras, Georgia D and Alam, S. Munir and Evans, David T and Montefiori, David C and Karnasuta, Chitraporn and Sutthent, Ruengpueng and Liao, Hua-Xin and DeVico, Anthony L and Lewis, George K and Williams, Constance and Pinter, Abraham and Fong, Youyi and Janes, Holly and DeCamp, Allan and Huang, Yunda and Rao, Mangala and Billings, Erik and Karasavvas, Nicos and Robb, Merlin L and Ngauy, Viseth and de Souza, Mark S and Paris, Robert and Ferrari, Guido and Bailer, Robert T and Soderberg, Kelly A and Andrews, Charla and Berman, Phillip W and Frahm, Nicole and De Rosa, Stephen C and Alpert, Michael D and Yates, Nicole L and Shen, Xiaoying and Koup, Richard A and Pitisuttithum, Punnee and Kaewkungwal, Jaranit and Nitayaphan, Sorachai and Rerks-Ngarm, Supachai and Michael, Nelson L and Kim, Jerome H
The New England Journal of Medicine, ISSN 0028-4793, 04/2012, Volume 366, Issue 14, pp. 1275 - 1286
This analysis of correlates of the risk of HIV-1 infection in the RV144 vaccine trial identifies hypotheses for improving efficacy. The data indicate key roles... 
DEPENDENT CELLULAR CYTOTOXICITY | V1/V2 DOMAIN | RESPONSES | SIV | CHALLENGE | MEDICINE, GENERAL & INTERNAL | PROTECTION | IMMUNODEFICIENCY-VIRUS | ANTIBODY | INFECTION | NEUTRALIZATION | HIV Antibodies - blood | HIV Infections - prevention & control | Multivariate Analysis | Follow-Up Studies | Humans | AIDS Vaccines - immunology | Risk | Treatment Outcome | Case-Control Studies | HIV Infections - immunology | Regression Analysis | HIV-1 - immunology | Immunoglobulin A - blood | Adult | Odds Ratio | Immunization | Immunoglobulin G | Human immunodeficiency virus--HIV | Infections | Lymphocytes T | Vaccines | Immunoglobulin A | Immune system
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