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Nature, ISSN 0028-0836, 2013, Volume 494, Issue 7436, pp. 201 - 206
The lysosomal degradation pathway of autophagy has a crucial role in defence against infection, neurodegenerative disorders, cancer and ageing. Accordingly,... 
PATHOGENESIS | LOCALIZES | COMPLEX | PROTEIN | BECLIN-1 | PATHWAY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | DISEASE | INFECTION | BINDING | Apoptosis Regulatory Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Humans | Cell Membrane Permeability | Molecular Sequence Data | Peptide Fragments - pharmacology | Membrane Proteins - pharmacology | Membrane Proteins - therapeutic use | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | HIV-1 - physiology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | Beclin-1 | Amino Acid Sequence | HIV-1 - metabolism | Virus Replication - drug effects | Peptide Fragments - metabolism | HIV-1 - drug effects | tat Gene Products, Human Immunodeficiency Virus - genetics | Apoptosis Regulatory Proteins - chemistry | Cells, Cultured | West Nile virus - drug effects | Macrophages - cytology | Recombinant Fusion Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Chikungunya virus - drug effects | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Mice | HeLa Cells | Apoptosis Regulatory Proteins - therapeutic use | tat Gene Products, Human Immunodeficiency Virus - metabolism | Proteins | Peptides | Microscopy | Rodents | Mortality | Amino acids | Infections | Autophagy | Index Medicus
Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 8, pp. 1829 - 1841
The t(8;21) translocation fuses the DNA-binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein... 
acute myeloid leukemia | chromatin | epigenetic regulation | integrated analysis of high-throughput data | RUNX1/ETO | AML1-ETO | STEM-CELLS | ACUTE MYELOGENOUS LEUKEMIA | SELF-RENEWAL | ACUTE MYELOID-LEUKEMIA | HEMATOPOIESIS | ONCOLOGY | IN-VIVO | FUSION PROTEIN | GENE-EXPRESSION | DIFFERENTIATION | HEMATOLOGY | Chromatin - metabolism | Translocation, Genetic | Oncogene Proteins, Fusion - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Transcriptional Activation | CCAAT-Binding Factor - genetics | Gene Expression Profiling | RNA Polymerase II - metabolism | Cell Differentiation - genetics | CCAAT-Binding Factor - metabolism | Acetylation | Binding Sites | Chromosomes, Human, Pair 21 | Proto-Oncogene Proteins - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Gene Silencing | Proto-Oncogene Proteins - genetics | Chromosomes, Human, Pair 8 | Transcription Factors - genetics | RUNX1 Translocation Partner 1 Protein | Transcription Factors - metabolism | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Protein Binding | Histones - metabolism | Mutation | Chromatin - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Cluster Analysis | Leukemia, Myeloid, Acute - genetics | Physiological aspects | Chromatin | Transcription factors | Research | Gene expression | Cell lines | Index Medicus | ETO | Original | RUNX1
Journal Article
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 2001, Volume 12, Issue 6, pp. 1699 - 1709
Homotypic fusion of immature secretory granules (ISGs) gives rise to mature secretory granules (MSGs), the storage compartment in endocrine and neuroendocrine... 
MEMBRANE-FUSION | RAB5 EFFECTOR | ENDOPEPTIDASE PC2 | ADRENAL CHROMAFFIN CELLS | TRANS-GOLGI NETWORK | ADAPTER PROTEIN AP-1 | SECRETOGRANIN-II | NEUROENDOCRINE CELLS | T-SNARE | VESICLE TRAFFICKING | CELL BIOLOGY | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/1991, Volume 115, Issue 6, pp. 1491 - 1503
Journal Article
EMBO Journal, ISSN 0261-4189, 1993, Volume 12, Issue 5, pp. 2159 - 2168
The role of the single, highly conserved disulfide bond in chromogranin B (secretogranin I) on the sorting of this regulated secretory protein to secretory... 
Chromogranin B | Trans-Golgi network | Disulfide bond | Secretion | VARIETY | CELLS | PROTEINS COMMON | BIOCHEMISTRY & MOLECULAR BIOLOGY | TYROSINE SULFATION | CHROMOGRANIN-B | BOVINE CHROMOGRANIN | DISULFIDE BOND | REGION | CELL BIOLOGY | PEPTIDES | GENE | GRANULE | TRANS-GOLGI NETWORK | SECRETION | AGGREGATION
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 9/1986, Volume 103, Issue 3, pp. 839 - 850
We have studied by electron microscopy and immunocytochemistry the formation of secretory granules containing adrenocorticotropic hormone (ACTH) in murine... 
Acinar cells | Beta cells | Secretory vesicles | Antiserum | Cell lines | Coated vesicles | Clathrin coated vesicles | Trans golgi network | Budding | Golgi apparatus | CELL BIOLOGY | pituitary | adrenocorticotropic hormone | mice | proteins | Index Medicus
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 08/2000, Volume 11, Issue 4, pp. 243 - 251
Proinsulin is packaged into nascent (immature, clathrin-coated) secretory granules in the trans-Golgi network (TGN) of the -cell along with other granular... 
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 5/1988, Volume 106, Issue 5, pp. 1475 - 1487
By pulse-chase labeling with [ S]methionine and long-term labeling with H-sugars, the E1 glycoprotein of coronavirus MHV-A59 has been shown to acquire O-linked... 
Virions | Viruses | Infections | Glycoproteins | Cell membranes | Oligosaccharides | Budding | Cells | Sugars | Golgi apparatus | CELL BIOLOGY | Index Medicus
Journal Article
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.], 2001, Volume 7, p. 7.3
Post-translational modifications of proteins make it possible to determine where a protein normally resides or to follow its transport through the cell. One... 
Isotope Labeling - methods | Animals | Proteins - metabolism | Humans | Tyrosine - analysis | Indicators and Reagents | Cells, Cultured - metabolism | Protein Processing, Post-Translational | Proteins - analysis | Sulfur Radioisotopes - analysis | Tyrosine - analogs & derivatives
Journal Article