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Blood, ISSN 0006-4971, 08/2016, Volume 128, Issue 6, pp. 743 - 745
In this issue of Blood, Brauer et al model altered T-cell development of severe combined immunodeficiency (SCID) and Omenn syndrome (OS) patients with human... 
GENE-EXPRESSION | RECEPTOR | THYMOCYTES | HEMATOLOGY | Lymphocyte Activation | Humans | Receptors, Antigen, T-Cell
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2017, Volume 214, Issue 11, pp. 3361 - 3379
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 20223
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2010, Volume 42, Issue 4, pp. 338 - 342
Journal Article
Blood, ISSN 0006-4971, 10/2003, Volume 102, Issue 7, pp. 2444 - 2451
Abstract Notch1 activity is essential for the specification of T-lineage fate in hematopoietic progenitors. Once the T-cell lineage is specified, T-cell... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 2014, Volume 193, Issue 10, pp. 5181 - 5189
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 04/2009, Volume 206, Issue 4, pp. 779 - 791
Notch1 activation is essential for T-lineage specification of lymphomyeloid progenitors seeding the thymus. Progression along the T cell lineage further... 
MEDICINE, RESEARCH & EXPERIMENTAL | PROGENITORS | POSITIVE SELECTION | ALPHA-CHAIN | GA-BINDING-PROTEIN | ACUTE LYMPHOBLASTIC-LEUKEMIA | PRE-TCR | DIFFERENTIATION | IMMUNOLOGY | BETA-SELECTION | CELL DEVELOPMENT | INTERLEUKIN-7 RECEPTOR
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 05/2017, Volume 37, Issue 9
Journal Article
2012, 2012, Current Topics in Microbiology and Immunology, ISBN 9783642242939, Volume 360, 27
Notch receptors are master regulators of many aspects of development and tissue renewal in metazoans. Notch1 activation is essential for T-cell specification... 
Biomedicine | Immunology | T-cell lineage | IL-7R | BETA-SELECTION CHECKPOINT | GA-BINDING-PROTEIN | Notch | HUMAN THYMIC DEVELOPMENT | MICROBIOLOGY | OF-FUNCTION MUTATIONS | IMMUNOLOGY | INTERLEUKIN-7 RECEPTOR | Thymus | lympho-myeloid progenitor | LINEAGE COMMITMENT | DELTA-LIKE 4 | ACUTE LYMPHOBLASTIC-LEUKEMIA | COMMON LYMPHOID PROGENITORS | leukaemia | NF-KAPPA-B
Book Chapter
Immunobiology, ISSN 0171-2985, 2010, Volume 215, Issue 9, pp. 812 - 820
Journal Article