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1. Full Text EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research
by Van Deun, Jan and Mestdagh, Pieter and Agostinis, Patrizia and Akay, Özden and Anand, Sushma and Anckaert, Jasper and Martinez, Zoraida Aneu and Baetens, Tine and Beghein, Els and Bertier, Laurence and Berx, Geert and Boere, Janneke and Boukouris, Stephanie and Bremer, Michel and Buschmann, Dominik and Byrd, James B and Casert, Clara and Cheng, Lesley and Cmoch, Anna and Daveloose, Delphine and De Smedt, Eva and Demirsoy, Seyma and Depoorter, Victoria and Dhondt, Bert and edonks, Tom A P and Dudek, Aleksana and Elsharawy, Abdou and Floris, Ilaria and Foers, Anew D and Gärtner, Kathrin and Garg, Abhishek D and Geeurickx, Edward and Gettemans, Jan and Ghazavi, Farzaneh and Giebel, Bernd and Kormelink, Tom Groot and Hancock, Grace and Helsmoortel, Hetty and Hill, Anew F and Hyenne, Vincent and Kalra, Hina and Kim, David and Kowal, Joanna and Kraemer, Sana and Leidinger, Petra and Leonelli, Carina and van der Grein, Susanne and van Herwijnen, Martijn J and Wauben, Marca and Zonneveld, Marijke I and t Hoen, E.N.M and EV-TRACK Consortium
Nature Methods, ISSN 1548-7091, 02/2017, Volume 14, Issue 3, pp. 228 - 232
We argue that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments. To... 
CELLS | NEED | SAMPLE COLLECTION | SUBPOPULATIONS | MINIMUM INFORMATION | COMPLEXES | BIOCHEMICAL RESEARCH METHODS | EXOSOMES | PHENOTYPE | STANDARDS | RELEASE | Extracellular Vesicles - physiology | Biomedical Research | Databases, Bibliographic | Internationality | Medicine, Experimental | Medical research | Extracellular matrix | Cell organelles | Observations | Reporting | Knowledge base | Biology | Life Sciences
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2. Full Text Genetics of Atypical Hemolytic Uremic Syndrome (aHUS)
by Rodríguez de Córdoba, Santiago and Hidalgo, Marta Subías and Pinto, Sheila and Tortajada, Agustín
Seminars in Thrombosis and Hemostasis, ISSN 0094-6176, 06/2014, Volume 40, Issue 4, pp. 422 - 430
Abstract Hemolytic uremic syndrome (HUS) is a rare, life-threatening disease characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute... 
aHUS | complement | thrombotic microangiopathy | C3 CONVERTASE | FACTOR-I | COMPLEMENT FACTOR-H | INHIBITOR ECULIZUMAB | ALTERNATIVE PATHWAY | ENDOTHELIAL-CELLS | BINDING-AFFINITY | TERMINAL REGION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | MEMBRANE COFACTOR PROTEIN | MOLECULAR-BASIS | Genetic Predisposition to Disease | Genetic Association Studies | Introns | Humans | Diacylglycerol Kinase - genetics | Thrombotic Microangiopathies - genetics | Autoantibodies - immunology | RNA Splicing | Complement Factor B - genetics | Complement System Proteins - genetics | Heterozygote | Mutation | Thrombomodulin - genetics | Complement Factor H - genetics | Atypical Hemolytic Uremic Syndrome - genetics | Complement C3 - genetics
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3. Full Text Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles
by Carreras-Planella, L and Monguio-Tortajada, M and Borras, FE and Franquesa, M
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 06/2019, Volume 10, p. 1288
Mesenchymal stem or stromal cells (MSC) have proven immunomodulatory properties toward B cell activation and induce regulatory B cells (Breg), through a dual... 
Ev isolation | mesenchymal stromal cells | memory B cell | immunosuppression | IMMUNOLOGY | STROMAL CELLS | CHROMATOGRAPHY | exosome | regulatory B cell | MESENCHYMAL STEM-CELLS | Stem cells | B cells | Usage | Research | Gel permeation chromatography
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4. Full Text Tolerance in organ transplantation: From conventional immunosuppression to extracellular vesicles
by Monguió-Tortajada, Marta and Lauzurica, Ricardo and Borràs, Francesc E
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, p. 416
Organ transplantation is often the unique solution for organ failure. However, rejection is still an unsolved problem. Although acute rejection is well... 
Graft survival | Extracellular vesicles | Tolerance | Transplantation immunology | Organ transplantation | Exosomes | Graft rejection | graft rejection | TOLEROGENIC DENDRITIC CELLS | extracellular vesicles | LONG-TERM SURVIVAL | REPERFUSION INJURY | graft survival | ALLOGRAFT SURVIVAL | IMMUNOLOGY | VERSUS-HOST-DISEASE | MESENCHYMAL STEM-CELLS | transplantation immunology | organ transplantation | exosomes | REGULATORY T-CELLS | NOVO KIDNEY-TRANSPLANTATION | PROTEOMIC ANALYSIS | PEPTIDE-BASED VACCINE | tolerance | Graft Rejection | Graft Survival | Organ Transplantation | Transplantation Immunology
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5. Full Text Extracellular vesicle isolation methods: rising impact of size-exclusion chromatography
by Monguio-Tortajada, M and Galvez-Monton, C and Bayes-Genis, A and Roura, S and Borras, FE
CELLULAR AND MOLECULAR LIFE SCIENCES, ISSN 1420-682X, 06/2019, Volume 76, Issue 12, pp. 2369 - 2382
Extracellular vesicles (EVs) include a variety of nanosized vesicles released to the extracellular microenvironment by the vast majority of cells transferring... 
CELLS | Purification | SUBPOPULATIONS | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROVESICLES | Exosomes | IDENTIFICATION | Theranostics | CELL BIOLOGY | LIQUID-CHROMATOGRAPHY | ULTRAFILTRATION | BIOGENESIS | Isolation methods | SEPARATION | Nanomedicine | Usage | RNA | Analysis | Physiological aspects | Lipids | Research institutes | Methods | Cells | Chromatography | Blood proteins | Size exclusion chromatography | Intercellular signalling | Laboratories | Immunomodulation | MiRNA | Ultracentrifugation | mRNA | Ribonucleic acid--RNA | Electron microscopy | Proteins | Heterogeneity | Vesicles | Plasma proteins | Quality standards | Biomarkers | Scaling | Conditioning | Non-coding RNA
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6. Full Text Bovine endometrial MSC: Mesenchymal to epithelial transition during luteolysis and tropism to implantation niche for immunomodulation
by Calle, Alexandra and López-Martín, Soraya and Monguió-Tortajada, Marta and Borràs, Francesc Enric and Yáñez-Mó, María and Ramírez, Miguel Ángel
Stem Cell Research and Therapy, ISSN 1757-6512, 01/2019, Volume 10, Issue 1, pp. 23 - 12
BackgroundThe uterus is a histologically dynamic organ, and the mechanisms coordinating its regeneration during the oestrous cycle and implantation are poorly... 
Embryo implantation | Inflammation | Endometrial mesenchymal stem cells | Cell migration | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | IMMUNE-SYSTEM | DECIDUALIZATION | MODEL | PREGNANCY | CELL BIOLOGY | Research | Cell differentiation | Gene expression | Epithelial cells | Stem cells | Vimentin | Cell proliferation | Tropism | Alkaline phosphatase | Mesenchyme | Oct-4 protein | Lymphocytes T | Metastasis | Estrus cycle | Phosphatase | Cell surface | Cell adhesion & migration | Cell growth | Uterus | Cattle | CD44 antigen | Fibroblasts | Tumor necrosis factor-TNF | Oviduct | Endometrium | Immune system | CD34 antigen | Estrus | Cytokines | Immunomodulation | Implantation | Tumor necrosis factor-α | Pregnancy | Immortalization | Cell lines | Interferon
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7. Full Text Mesenchymal stem cells induce expression of CD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo
by Monguió-Tortajada, Marta and Roura, Santiago and Gálvez-Montón, Carolina and Franquesa, Marcella and Bayes-Genis, Antoni and Borràs, Francesc E
Frontiers in Immunology, ISSN 1664-3224, 11/2017, Volume 8, p. 1577
The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado),... 
Mesenchymal stem cell | Myocardial infarction | Regeneration | Adenosine | CD73 | Immunomodulation | Purigernic signaling | Ectonucleotidase | immunomodulation | mesenchymal stem cell | FUNCTIONAL RECOVERY | ACTIVATION | DENDRITIC CELLS | MACROPHAGES | myocardial infarction | IMMUNOLOGY | adenosine | ADENOSINE A(2A) RECEPTORS | regenerationIN | REGULATORY T-CELLS | CD39 | GENERATION | purigernic signaling | STROMAL CELLS | ectonucleotidase | INHIBIT | Monocytes | Genetic aspects | Health aspects | Heart attack | Stem cells
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8. Full Text Size-Exclusion Chromatography-based isolation minimally alters Extracellular Vesicles' characteristics compared to precipitating agents
by Gámez-Valero, Ana and Monguió-Tortajada, Marta and Carreras-Planella, Laura and Franquesa, Marcella and Beyer, Katrin and Borràs, Francesc E
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, p. 33641
Extracellular vesicles (EVs) have become an attractive field among the scientific community. Yet, a major challenge is to define a consensus method for EVs... 
BIOMARKERS | EXOSOMES | PROTOCOL | DISEASES | MICROPARTICLES | MULTIDISCIPLINARY SCIENCES | Proteins | CD9 antigen | Vesicles | Plasma proteins | CD63 antigen | Polyethylene glycol | CD81 antigen | Ultracentrifugation | Electron microscopy | Chromatography
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9. Full Text Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications
by Subías Hidalgo, Marta and Yébenes, Hugo and Rodríguez‐Gallego, César and Martín‐Ambrosio, Adrián and Domínguez, Mercedes and Tortajada, Agustin and Rodríguez de Córdoba, Santiago and Llorca, Oscar
European Journal of Immunology, ISSN 0014-2980, 03/2017, Volume 47, Issue 3, pp. 504 - 515
C3 is the central component of the complement system. Upon activation, C3 sequentially generates various proteolytic fragments, C3a, C3b, iC3b, C3dg, each of... 
C3b | Complement inhibition | Monoclonal antibody | C3bBb convertase | ACTIVATION | FACTOR-B | MECHANISM | ELECTRON-MICROSCOPY | FACTOR-H | 2 PARTS | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | IMMUNOLOGY | INHIBITION | ALTERNATIVE PATHWAY | DISEASE | Complement C3-C5 Convertases - metabolism | Immunoglobulin Fab Fragments - genetics | Complement C3 - metabolism | Humans | Complement C3 - immunology | Mice, Knockout | Antibodies, Monoclonal - genetics | Animals | Genetic Engineering | Hybridomas | Protein Binding | Protein Conformation | Mice | Antibodies, Monoclonal - metabolism | Antigen-Antibody Complex - metabolism | Complement Pathway, Alternative | Complement C3 - genetics | Hemolytic Plaque Technique | Proteins | Immunohistochemistry | Monoclonal antibodies | Health aspects
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10. Full Text Preclinical evaluation of the immunomodulatory properties of cardiac adipose tissue progenitor cells using umbilical cord blood mesenchymal stem cells: A direct comparative study
by Perea-Gil, Isaac and Monguió-Tortajada, Marta and Gálvez-Montón, Carolina and Bayes-Genis, Antoni and Borràs, Francesc E and Roura, Santiago
BioMed Research International, ISSN 2314-6133, 2015, Volume 2015, pp. 439808 - 9
Cell-based strategies to regenerate injured myocardial tissue have emerged over the past decade, but the optimum cell type is still under scrutiny. In this... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | IN-VITRO | THERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | REGENERATION | DIFFERENTIATION | VERSUS-HOST-DISEASE | MARROW STROMAL CELLS | INHIBIT | LYMPHOCYTE-PROLIFERATION | TRANSPLANTATION | Fetal Blood - immunology | Stem Cells - immunology | Antibody Formation - immunology | Heart - physiology | Humans | Cells, Cultured | Immunologic Factors - immunology | Umbilical Cord - immunology | T-Lymphocytes - immunology | Adipose Tissue - immunology | Coculture Techniques - methods | Mesenchymal Stromal Cells - immunology | Adipose tissues | Cell interaction | T cells | Observations | Health aspects | Stem cells | Studies | Heart failure | Cytokines | Laboratories | Blood
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11. Full Text Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes
by Monguio-Tortajada, M and Franquesa, M and Sarrias, MR and Borras, FE
CELL DEATH & DISEASE, ISSN 2041-4889, 05/2018, Volume 9, Issue 5, pp. 499 - 14
TLR sensing of pathogens triggers monocyte activation to initiate the host innate immune response to infection Monocytes can dynamically adapt to different TLR... 
SIGNALING PATHWAYS | INFLUENZA-A VIRUS | DENDRITIC CELLS | INDUCIBLE GENE-I | HUMAN MACROPHAGES | TOLL-LIKE RECEPTORS | RIG-I | ACUTE-RENAL-FAILURE | INTRACELLULAR LPS | PATTERN-RECOGNITION RECEPTORS | CELL BIOLOGY | Tumor necrosis factor receptors | Antigen presentation | TLR7 protein | Immune response | Poly (I:C) | Inflammation | TLR4 protein | Tumor necrosis factor-α | Immunological tolerance | TLR3 protein | Lipopolysaccharides | Interleukin 6 | Monocytes | Cell activation | Cell death | Toll-like receptors | MyD88 protein | Apoptosis
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12. Full Text 4th Pediatric Allergy and Asthma Meeting (PAAM)
by Yavuz, S. Tolga and Koc, Ozan and Gungor, Ali and Gok, Faysal and Hawley, Jessica and O’Brien, Christopher and Thomas, Matthew and Brodlie, Malcolm and Michaelis, Louise and Mota, Inês and Gaspar, Ângela and Piedade, Susana and Sampaio, Graça and Dias, José Geraldo and Paiva, Miguel and Morais-Almeida, Mário and Madureira, Cristina and Lopes, Tânia and Lopes, Susana and Almeida, Filipa and Sequeira, Alexandra and Carvalho, Fernanda and Oliveira, José and Gay-Crosier, Fabienne and Nenciu, Ioana-Valentina and Nita, Andreia Florina and Ulmeanu, Alexandru and Oraseanu, Dumitru and Zapucioiu, Carmen and Machinena, Adrianna and Sánchez, Olga Domínguez and Lozano, Montserrat Alvaro and Feijoo, Rosa Jiménez and Blasco, Jaime Lozano and Gibert, Mònica Piquer and Muñoz, Mª Teresa Giner and da Costa, Marcia Dias and Martín, Ana Maria Plaza and Yilmaz, Ebru Arik and Cavkaytar, Özlem and Buyuktiryaki, Betul and Soyer, Ozge and Sackesen, Cansin and Netting, Merryn and El-Merhibi, Adaweyah and Gold, Michael and Quinn, Patrick and Penttila, Irmeli and Makrides, Maria and Giavi, Stavroula and Muraro, Antonella and Lauener, Roger and Mercenier, Annick and Bersuch, Eugen and Montagner, Isabella M and Passioti, Maria and Celegato, Nicolò and Summermatter, Selina and Nutten, Sophie and Bourdeau, Tristan and Vissers, Yvonne M and Papadopoulos, Nikolaos G and van der Kleij, Hanneke and Warmenhoven, Hans and van Ree, Ronald and Pieters, Raymond and Opstelten, Dirk Jan and van Schijndel, Hans and Smit, Joost and Fitzsimons, Roisin and Timms, Victoria and Du Toit, George and Kaya, Guven and Gulec, Mustafa and Saldir, Mehmet and Sener, Osman and Hassan, Nagwa and Shaaban, Hala and El-Hariri, Hazem and Mahfouz, Ahmed Kamel Inas E and Gabor, Papp and Gabor, Biro and Csaba, Kovacs and Chawes, Bo and Bønnelykke, Klaus and Stokholm, Jakob and Heickendorff, Lene and Brix, Susanne and Rasmussen, Morten and Bisgaard, Hans and Hallas, Henrik Wegener and Arianto, Lambang and Pincus, Maike and Keil, Thomas and Reich, Andreas and Wahn, Ulrich and Lau, Susanne and Grabenhenrich, Linus and Fagerstedt, Sara and Hesla, Helena Marell and ... and Allergy Vigilance Network and the Bilastine Pediatric Safety Study Group and on behalf of the PiCA consortium
Clinical and Translational Allergy, ISSN 2045-7022, 11/2016, Volume 6, Issue S1
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13. Full Text Molecular basis of factor H R1210C association with ocular and renal diseases
by Recalde, Sergio and Tortajada, Agustin and Subias, Marta and Anter, Jaouad and Blasco, Miquel and Maranta, Ramona and Coco, Rosa and Pinto, Sheila and Noris, Marina and García-Layana, Alfredo and De Córdoba, Santiago Rodríguez
Journal of the American Society of Nephrology, ISSN 1046-6673, 05/2016, Volume 27, Issue 5, pp. 1305 - 1311
The complement factor H (FH) mutation R1210C, which was described in association with atypical hemolytic uremic syndrome (aHUS), also confers high risk of... 
Macular Degeneration - genetics | Pedigree | Complement C3 | Humans | Middle Aged | Female | Male | Mutation | Complement Factor H - genetics | Atypical Hemolytic Uremic Syndrome - genetics | Kidney Diseases - genetics | Kidney Glomerulus | glomerular disease | complement | hemolytic uremic syndrome | Brief Communications
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