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1. Full Text Drug therapy: EGFR antagonists in cancer treatment
by Ciardiello, Fortunato and Tortora, Giampaolo
The New England journal of medicine, ISSN 0028-4793, 03/2008, Volume 358, Issue 11, pp. 1160 - 1174
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology
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2. Full Text Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer
by Golan, Talia and Hammel, Pascal and Reni, Michele and Van Cutsem, Eric and Macarulla, Teresa and Hall, Michael J and Park, Joon-Oh and Hochhauser, Daniel and Arnold, Dirk and Oh, Do-Youn and Reinacher-Schick, Anke and Tortora, Giampaolo and Algül, Hana and O’Reilly, Eileen M and McGuinness, David and Cui, Karen Y and Schlienger, Katia and Locker, Gershon Y and Kindler, Hedy L
The New England journal of medicine, ISSN 0028-4793, 07/2019, Volume 381, Issue 4, pp. 317 - 327
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Maintenance Chemotherapy - adverse effects | Pancreatic Neoplasms - drug therapy | Neoplasm Metastasis - drug therapy | Antineoplastic Agents - adverse effects | Aged, 80 and over | Genes, BRCA2 | Germ-Line Mutation | Adult | Female | Adenocarcinoma - genetics | Pancreatic Neoplasms - mortality | Genes, BRCA1 | Double-Blind Method | Pancreatic Neoplasms - pathology | Kaplan-Meier Estimate | Pancreatic Neoplasms - genetics | Piperazines - therapeutic use | Adenocarcinoma - drug therapy | Piperazines - adverse effects | Adenocarcinoma - secondary | Phthalazines - therapeutic use | Progression-Free Survival | Aged | Phthalazines - adverse effects | Adenocarcinoma - mortality | Genetic aspects | Research | Drug therapy | BRCA mutations | Pancreatic cancer | Intervention | BRCA2 protein | Adenosine | Medical imaging | Tablets | BRCA1 protein | Poly(ADP-ribose) polymerase | Breast cancer | Metastasis | Cancer therapies | Survival | Metastases | Ovarian cancer | Quality of life | Chemotherapy | Ribose | Platinum | Antitumor activity | Mutation | Health risk assessment | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Abridged Index Medicus
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3. Full Text A Novel Approach in the Treatment of Cancer: Targeting the Epidermal Growth Factor Receptor
by Fortunato Ciardiello and Giampaolo Tortora
Clinical Cancer Research, ISSN 1078-0432, 10/2001, Volume 7, Issue 10, pp. 2958 - 2970
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Erlotinib Hydrochloride | Receptor, Epidermal Growth Factor - immunology | Antineoplastic Agents - immunology | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Antibodies, Monoclonal, Humanized | Animals | Quinazolines - therapeutic use | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Cetuximab | Antibodies, Monoclonal - immunology | Index Medicus
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4. Full Text Cabozantinib-related pneumothorax in rapidly responding patients with renal cell carcinoma
by Iacovelli, Roberto and Ciccarese, Chiara and Mosillo, Claudia and Tortora, Giampaolo
The lancet oncology, ISSN 1470-2045, 02/2019, Volume 20, Issue 2, pp. e124 - e124
Index Medicus
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5. Pancreatic cancer: Systemic combination therapies for a heterogeneous disease
by Melisi, Davide and Calvetti, Lorenzo and Frizziero, Melissa and Tortora, Giampaolo
Current pharmaceutical design, ISSN 1381-6128, 03/2014, Volume 20, Issue 42, pp. 6660 - 6669
FOLFIRINOX | Pancreatic cancer | Combination therapies | Hypoxia | TGF-β | Drug resistance | Nab-paclitaxel | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Pancreatic Neoplasms - drug therapy | Pancreatic Neoplasms - metabolism | Drug Therapy, Combination | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Pancreatic Neoplasms - pathology
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6. Full Text Genomic analyses identify molecular subtypes of pancreatic cancer
by Bailey, Peter and Chang, David K and Nones, Katia and Johns, Amber L and Patch, Ann-Marie and Gingras, Marie-Claude and Miller, David K and Christ, Angelika N and Bruxner, Tim J. C and Quinn, Michael C and Nourse, Craig and Murtaugh, L. Charles and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourbakhsh, Ehsan and Wani, Shivangi and Fink, Lynn and Holmes, Oliver and Chin, Venessa and Anderson, Matthew J and Kazakoff, Stephen and Leonard, Conrad and Newell, Felicity and Waddell, Nick and Wood, Scott and Xu, Qinying and Wilson, Peter J and Cloonan, Nicole and Kassahn, Karin S and Taylor, Darrin and Quek, Kelly and Robertson, Alan and Pantano, Lorena and Mincarelli, Laura and Sanchez, Luis N and Evers, Lisa and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Jones, Marc D and Colvin, Emily K and Nagrial, Adnan M and Humphrey, Emily S and Chantrill, Lorraine A and Mawson, Amanda and Humphris, Jeremy and Chou, Angela and Pajic, Marina and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Lovell, Jessica A and Merrett, Neil D and Toon, Christopher W and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Moran-Jones, Kim and Jamieson, Nigel B and Graham, Janet S and Duthie, Fraser and Oien, Karin and Hair, Jane and Grützmann, Robert and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Rusev, Borislav and Capelli, Paola and Salvia, Roberto and Tortora, Giampaolo and Mukhopadhyay, Debabrata and Petersen, Gloria M and Munzy, Donna M and Fisher, William E and Karim, Saadia A and Eshleman, James R and Hruban, Ralph H and Pilarsky, Christian and Morton, Jennifer P and Sansom, Owen J and Scarpa, Aldo and Musgrove, Elizabeth A and Bailey, Ulla-Maja Hagbo and Hofmann, Oliver and Sutherland, Robert L and Wheeler, David A and Gill, Anthony J and Gibbs, Richard A and Pearson, John V and Waddell, Nicola and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature (London), ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 47 - 52
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Pancreatic Neoplasms - metabolism | Prognosis | Hepatocyte Nuclear Factor 3-beta - genetics | Genomics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Hepatocyte Nuclear Factor 3-gamma - genetics | Gene Regulatory Networks | Histone Demethylases - genetics | Tumor Suppressor Protein p53 - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Methylation | Tumor Suppressor Proteins - genetics | Carcinoma, Pancreatic Ductal - classification | Trans-Activators - genetics | Pancreatic Neoplasms - classification | Transcription, Genetic | Nuclear Proteins - genetics | Carcinoma, Pancreatic Ductal - immunology | Genes, Neoplasm - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Pancreatic Neoplasms - pathology | Zebrafish Proteins | Pancreatic Neoplasms - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Genome, Human - genetics | Homeodomain Proteins - genetics | Animals | Pancreatic Neoplasms - immunology | Survival Analysis | Cell Line, Tumor | Mice | Physiological aspects | Pancreatic cancer | Methods | Genes | Genomes | Mutation | Gene expression | Tumors | Index Medicus
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7. Full Text Patients with sarcomatoid renal cell carcinoma – re-defining the first-line of treatment: A meta-analysis of randomised clinical trials with immune checkpoint inhibitors
by Iacovelli, Roberto and Ciccarese, Chiara and Bria, Emilio and Bracarda, Sergio and Porta, Camillo and Procopio, Giuseppe and Tortora, Giampaolo
European journal of cancer (1990), ISSN 0959-8049, 09/2020, Volume 136, pp. 195 - 203
Sarcomatoid RCC | Renal cell carcinoma | Immune checkpoint inhibitor combinations | Immunotherapy | Life Sciences & Biomedicine | Oncology | Science & Technology | Carcinoma, Renal cell | Health services | Clinical trials | Survival | Patients | Confidence intervals | Heterogeneity | Angiogenesis | Immune checkpoint | Antiangiogenics | Medical prognosis | Kidney cancer | Risk management | Clear cell-type renal cell carcinoma | Index Medicus
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8. Full Text Whole genomes redefine the mutational landscape of pancreatic cancer
by Waddell, Nicola and Pajic, Marina and Patch, Ann-Marie and Chang, David K and Kassahn, Karin S and Bailey, Peter and Johns, Amber L and Miller, David and Nones, Katia and Quek, Kelly and Quinn, Michael C. J and Robertson, Alan J and Fadlullah, Muhammad Z. H and Bruxner, Tim J. C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wani, Shivangi and Wilson, Peter J and Markham, Emma and Cloonan, Nicole and Anderson, Matthew J and Fink, J. Lynn and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Newell, Felicity and Poudel, Barsha and Song, Sarah and Taylor, Darrin and Waddell, Nick and Wood, Scott and Xu, Qinying and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Lee, Hong C and Jones, Marc D and Nagrial, Adnan M and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Steinmann, Angela M and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Pettitt, Jessica A and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Jamieson, Nigel B and Graham, Janet S and Niclou, Simone P and Bjerkvig, Rolf and Grützmann, Robert and Aust, Daniela and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Falconi, Massimo and Zamboni, Giuseppe and Tortora, Giampaolo and Tempero, Margaret A and Gill, Anthony J and Eshleman, James R and Pilarsky, Christian and Scarpa, Aldo and Musgrove, Elizabeth A and Pearson, John V and Biankin, Andrew V and Grimmond, Sean M and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature (London), ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 495 - 501
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genomics | Humans | DNA Repair - genetics | Carcinoma, Pancreatic Ductal - genetics | Pancreatic Neoplasms - drug therapy | Point Mutation - genetics | DNA Mutational Analysis | Genes, BRCA2 | Pancreatic Neoplasms - classification | Female | Adenocarcinoma - genetics | Genes, BRCA1 | Platinum - pharmacology | Genomic Instability - genetics | Genotype | Pancreatic Neoplasms - genetics | Mutation - genetics | Adenocarcinoma - drug therapy | Poly(ADP-ribose) Polymerase Inhibitors | Genome, Human - genetics | Xenograft Model Antitumor Assays | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Genetic Markers - genetics | Mice | Copy number variations | Pancreatic cancer | Physiological aspects | Development and progression | Genetic aspects | Research | Tumor proteins | Risk factors | Genes | DNA damage | Clinical trials | Genomes | Cancer therapies | Patients | Biomarkers | Mutation | Chromosomes | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
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9. Full Text Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
by Jiao, Yuchen and Pawlik, Timothy M and Anders, Robert A and Selaru, Florin M and Streppel, Mirte M and Lucas, Donald J and Niknafs, Noushin and Guthrie, Violeta Beleva and Maitra, Anirban and Argani, Pedram and Offerhaus, G Johan A and Roa, Juan Carlos and Roberts, Lewis R and Gores, Gregory J and Popescu, Irinel and Alexandrescu, Sorin T and Dima, Simona and Fassan, Matteo and Simbolo, Michele and Mafficini, Andrea and Capelli, Paola and Lawlor, Rita T and Ruzzenente, Andrea and Guglielmi, Alfredo and Tortora, Giampaolo and De Braud, Filippo and Scarpa, Aldo and Jarnagin, William and Klimstra, David and Karchin, Rachel and Velculescu, Victor E and Hruban, Ralph H and Vogelstein, Bert and Kinzler, Kenneth W and Papadopoulos, Nickolas and Wood, Laura D
Nature genetics, ISSN 1061-4036, 12/2013, Volume 45, Issue 12, pp. 1470 - 1473
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Liver Neoplasms - genetic