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Acta Neuropathologica, ISSN 0001-6322, 4/2017, Volume 133, Issue 4, pp. 629 - 644
Mutations in codon 132 of isocitrate dehydrogenase (IDH) 1 are frequent in diffuse glioma, acute myeloid leukemia, chondrosarcoma and intrahepatic... 
Pathology | Therapy | Neurosciences | IDH-mutated glioma | Medicine & Public Health | IDH1R132 inhibitor | Pharmacology | Drug development | Mouse xenograft | SELECTIVE-INHIBITION | GLIOMAS | ISOCITRATE DEHYDROGENASE | PHENOTYPE | ACUTE MYELOID-LEUKEMIA | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | BRAIN-TUMORS | GLIOBLASTOMAS | TUMOR STEM-CELLS | MUTATIONS | DIFFERENTIATION | Benzimidazoles - toxicity | Colonic Neoplasms - genetics | Colonic Neoplasms - drug therapy | Escherichia coli | Humans | Sarcoma - enzymology | Benzimidazoles - chemistry | Isocitrate Dehydrogenase - antagonists & inhibitors | Antineoplastic Agents - toxicity | Sf9 Cells | Enzyme Inhibitors - pharmacokinetics | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Astrocytoma - drug therapy | HEK293 Cells | Astrocytoma - enzymology | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Sarcoma - genetics | Cell Survival - physiology | Astrocytoma - genetics | Recombinant Proteins - metabolism | Cell Survival - drug effects | Brain Neoplasms - enzymology | Aniline Compounds - pharmacology | Enzyme Inhibitors - pharmacology | Benzimidazoles - pharmacokinetics | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Recombinant Proteins - genetics | Aniline Compounds - pharmacokinetics | Aniline Compounds - toxicity | Antineoplastic Agents - chemistry | Brain Neoplasms - drug therapy | Sarcoma - drug therapy | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Benzimidazoles - pharmacology | Isocitrate Dehydrogenase - metabolism | Colonic Neoplasms - enzymology | Glutarates - metabolism | Mice, Inbred BALB C | Aniline Compounds - chemistry | Mutation | Gliomas | Genetic aspects | Codon | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 3790 - 3790
Two well-established hallmarks of cancer are the need for nucleotides to support continuous cell proliferation and the requirement for cancer cell redox... 
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 4/2013, Volume 138, Issue 2, pp. 437 - 456
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 4460 - 4460
Journal Article
Journal Article
ISSN 1742-206X, 11/2015, Volume 11, Issue 12, pp. 3378 - 3386
We investigated the changes in amino acid (AA) metabolism induced in MCF10A, a human mammary epithelial cell line, by the sequential knock-in of K-Ras and PI3K... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 745 - 745
Abstract Background: Mutations in the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) are frequently found in patients with acute myeloid leukemia (AML) and... 
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 09/2011, Volume 17, Issue 18, p. 6000
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/1988, Volume 107, Issue 5, pp. 1623 - 1628
UV irradiation of quiescent human fibroblasts immediately triggers the appearance of the nuclear protein cyclin/proliferating cell nuclear antigen (PCNA) as... 
DNA replication | Cell growth | 3T3 cells | DNA | Cell nucleus | Irradiation | HeLa cells | Cellular immunity | DNA repair | Cells
Journal Article
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