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1. Full Text Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
by Rolland, Morgane and Edlefsen, Paul T and Larsen, Brendan B and Tovanabutra, Sodsai and Sanders-Buell, Eric and Hertz, Tomer and Decamp, Allan C and Carrico, Chris and Menis, Sergey and Magaret, Craig A and Ahmed, Hasan and Juraska, Michal and Chen, Lennie and Konopa, Philip and Nariya, Snehal and Stoddard, Julia N and Wong, Kim and Zhao, Hong and Deng, Wenjie and Maust, Brandon S and Bose, Meera and Howell, Shana and Bates, Adam and Lazzaro, Michelle and O'Sullivan, Annemarie and Lei, Esther and Bradfield, Andrea and Ibitamuno, Grace and Assawadarachai, Vatcharain and O'Connell, Robert J and Desouza, Mark S and Nitayaphan, Sorachai and Rerks-Ngarm, Supachai and Robb, Merlin L and McLellan, Jason S and Georgiev, Ivelin and Kwong, Peter D and Carlson, Jonathan M and Michael, Nelson L and Schief, William R and Gilbert, Peter B and Mullins, James I and Kim, Jerome H
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7420, pp. 417 - 420
The RV144 trial demonstrated 31% vaccine efficacy at preventing human immunodeficiency virus (HIV)-1 infection(1). Antibodies against the HIV-1 envelope... 
TRIAL | SUBTYPE-C | THAILAND | PROTECTION | SEQUENCES | MULTIDISCIPLINARY SCIENCES | COMPETING RISKS | INFECTION | AIDSVAX | NEUTRALIZATION | EPITOPES | HIV Infections - prevention & control | Genetic Predisposition to Disease | env Gene Products, Human Immunodeficiency Virus - immunology | HIV Infections - virology | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Phylogeny | HIV-1 - genetics | Sequence Analysis, DNA | AIDS Vaccines - adverse effects | Randomized Controlled Trials as Topic | HIV Infections - immunology | HIV-1 - immunology | env Gene Products, Human Immunodeficiency Virus - genetics | HIV Antibodies - immunology | Prevention | AIDS vaccines | Research | Health aspects | HIV infection | Confidence intervals | Genotype & phenotype | Immunization | Acquired immune deficiency syndrome--AIDS | Amino acids | Statistical methods | Vaccines | Mutation | Binding sites | Index Medicus
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2. Full Text Prospective study of acute HIV-1 infection in adults in East Africa and Thailand
by Robb, Merlin L and Eller, Leigh A and Kibuuka, Hannah and Rono, Kathleen and Maganga, Lucas and Nitayaphan, Sorachai and Kroon, Eugene and Sawe, Fred K and Sinei, Samuel and Sriplienchan, Somchai and Jagodzinski, Linda L and Malia, Jennifer and Manak, Mark and De Souza, Mark S and Tovanabutra, Sodsai and Sanders-Buell, Eric and Rolland, Morgane and Dorsey-Spitz, Julie and Eller, Michael A and Milazzo, Mark and Li, Qun and Lewandowski, Andrew and Wu, Hao and Swann, Edith and O'Connell, Robert J and Peel, Sheila and Dawson, Peter and Kim, Jerome H and Michael, Nelson L and RV 217 Study Team
New England Journal of Medicine, ISSN 0028-4793, 06/2016, Volume 374, Issue 22, pp. 2120 - 2130
BACKGROUND Acute human immunodeficiency virus type 1 (HIV-1) infection is a major contributor to transmission of HIV-1. An understanding of acute HIV-1... 
VIRAL LOAD | MEDICINE, GENERAL & INTERNAL | RNA LEVELS | TRANSMISSION | T-CELL-ACTIVATION | SET-POINT | DYNAMICS | 1ST YEAR | ANTIRETROVIRAL THERAPY | VIRUS TYPE-1 INFECTION | PROGRESSION | Africa, Eastern | Viremia - diagnosis | Prospective Studies | HIV Infections - virology | Humans | Middle Aged | Male | RNA, Viral - blood | CD4 Lymphocyte Count | HIV-1 - genetics | Thailand | Antibodies, Viral - blood | Disease Progression | Viral Load | HIV-1 - immunology | HIV-1 - isolation & purification | HIV Infections - diagnosis | Adolescent | Adult | Female | Prevention | Symptomatology | Care and treatment | Viremia | Analysis | HIV infection | Risk factors | Antiretroviral drugs | Disease transmission | Infectious diseases | Lymphocytes | Human immunodeficiency virus--HIV | Hypersensitivity | Antibodies | Enzyme immunoassay | Drug therapy | Ribonucleic acid--RNA | Viral infections | Index Medicus | Abridged Index Medicus
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3. Full Text Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials
by David C. Montefiori and Chitraporn Karnasuta and Ying Huang and Hasan Ahmed and Peter Gilbert and Mark S. de Souza and Robert McLinden and Sodsai Tovanabutra and Agnes Laurence-Chenine and Eric Sanders-Buell and M. Anthony Moody and Mattia Bonsignori and Christina Ochsenbauer and John Kappes and Haili Tang and Kelli Greene and Hongmei Gao and Celia C. LaBranche and Charla Andrews and Victoria R. Polonis and Supachai Rerks-Ngarm and Punnee Pitisuttithum and Sorachai Nitayaphan and Jaranit Kaewkungwal and Steve G. Self and Phillip W. Berman and Donald Francis and Faruk Sinangil and Carter Lee and Jim Tartaglia and Merlin L. Robb and Barton F. Haynes and Nelson L. Michael and Jerome H. Kim
The Journal of Infectious Diseases, ISSN 0022-1899, 8/2012, Volume 206, Issue 3, pp. 431 - 441
Background. A recombinant canarypox vector expressing human immunodeficiency virus type 1 (HIV-1) Gag, Pro, and membrane-linked gp120 (vCP1521), combined with... 
HIV/AIDS | Inoculation | Neutralizing antibodies | Vaccination | Response rates | Antibodies | Placebos | Monoclonal antibodies | Viruses | Infections | HIV 1 | INFECTIOUS DISEASES | PROTECTION | MICROBIOLOGY | PHASE-3 | IMMUNOLOGY | THAILAND | CHIMERIC VIRUS | IMMUNODEFICIENCY-VIRUS TYPE-1 | DOUBLE-BLIND | INFECTION | MONOCLONAL-ANTIBODIES | BINDING | SUBTYPE-B | HIV Antibodies - blood | HIV Infections - blood | Epitope Mapping | HIV Infections - prevention & control | Human Immunodeficiency Virus Proteins - immunology | HIV Infections - epidemiology | Humans | Thailand - epidemiology | AIDS Vaccines - immunology | Substance Abuse, Intravenous | Antibodies, Monoclonal - blood | HIV-1 - immunology | Canarypox virus | Immunization Schedule | AIDS Vaccines - administration & dosage | Antibodies, Monoclonal - immunology | Antibodies, Neutralizing - blood | Viral antibodies | AIDS vaccines | Usage | Research | Analysis | Index Medicus | Abridged Index Medicus | Major and Brief Reports
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4. Full Text Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection
by Colby, DJ and Trautmann, L and Pinyakorn, S and Leyre, L and Pagliuzza, A and Kroon, E and Rolland, M and Takata, H and Buranapraditkun, S and Intasan, J and Chomchey, N and Muir, R and Haddad, EK and Tovanabutra, S and Ubolyam, S and Bolton, DL and Fullmer, BA and Gorelick, RJ and Fox, L and Crowell, TA and Trichavaroj, R and O'Connell, R and Chomont, N and Kim, JH and Michael, NL and Robb, ML and Phanuphak, N and Ananworanich, J and Rv411 Study Grp and RV411 study group and The RV411 study group
NATURE MEDICINE, ISSN 1078-8956, 07/2018, Volume 24, Issue 7, pp. 923 - 923
Antiretroviral therapy during the earliest stage of acute HIV infection (Fiebig I) might minimize establishment of a latent HIV reservoir and thereby... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | THERAPY | PLASMA | PERSISTENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | MACAQUES | LATENT RESERVOIR | CELL BIOLOGY | Antiretroviral Therapy, Highly Active | HIV Infections - immunology | Acute Disease | RNA, Viral - genetics | HIV Infections - genetics | Humans | HIV Infections - drug therapy | HIV-1 - genetics | Viral Load | Antiviral agents | Genotype | Dosage and administration | Genetic aspects | Research | Drug therapy | HIV infection | Antiretroviral drugs | Interruption | Antiretroviral agents | Human immunodeficiency virus--HIV | Infections | Ribonucleic acid--RNA | Antiretroviral therapy | Index Medicus
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5. Full Text Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial
by Magaret, Craig A and Bradfield, Andrea and O'Sullivan, Annemarie and Gilbert, Peter B and Nau, Marty and Dubey, Sheri and Robertson, Michael N and Maust, Brandon S and Corey, Lawrence and Heath, Laura and Buchbinder, Susan and Mullins, James I and Tovanabutra, Sodsai and Li, Fusheng and Stoddard, Julia N and Frahm, Nicole and Wong, Kim and Sanders-Buell, Eric and Hural, John and Shiver, John and McCutchan, Francine E and Bose, Meera and Sorensen, Stephanie and Duerr, Ann and Crossler, Jacqueline and Raugi, Dana N and Jones, Teresa and deCamp, Allan C and McElrath, M Juliana and Zhao, Hong and Kim, Jerome and Self, Steve G and Rolland, Morgane and Deng, Wenjie and Casimiro, Danilo R and Michael, Nelson L
Nature Medicine, ISSN 1078-8956, 03/2011, Volume 17, Issue 3, pp. 366 - 371
We analyzed HIV-1 genome sequences from 68 newly infected volunteers in the STEP HIV-1 vaccine trial. To determine whether the vaccine exerted selective T cell... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | CELL RESPONSES | BIOCHEMISTRY & MOLECULAR BIOLOGY | T-LYMPHOCYTE RESPONSE | GAG | BINDING | ESCAPE | PREDICTION | CELL BIOLOGY | T-Lymphocytes, Cytotoxic - immunology | Humans | Molecular Sequence Data | Male | Phylogeny | HIV-1 - genetics | HIV-1 - classification | HIV Infections - immunology | HIV-1 - chemistry | Placebos | Female | Epitopes - chemistry | AIDS Vaccines - administration & dosage | Genes | Vaccination | Physiological aspects | Genetic aspects | Research | HIV (Viruses) | Health aspects | Clinical trials | Immunology | Vaccines | Lymphocytes | Human immunodeficiency virus--HIV | Genomics | Index Medicus
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6. Full Text A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer
by Ananthaswamy, Neeti and Fang, Qianglin and AlSalmi, Wadad and Jain, Swati and Chen, Zhenguo and Klose, Thomas and Sun, Yingyuan and Liu, Yue and Mahalingam, Marthandan and Chand, Subhash and Tovanabutra, Sodsai and Robb, Merlin L and Rossmann, Michael G and Rao, Venigalla B
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 873 - 10
The envelope protein of human immunodeficiency virus-1 (HIV-1) and its fusion peptide are essential for cell entry and vaccine design. Here, we describe the... 
SWISS-MODEL | NEUTRALIZING ANTIBODIES | PROTEIN | RECOGNITION | CRYSTAL-STRUCTURE | STABILIZATION | MULTIDISCIPLINARY SCIENCES | GLYCOPROTEIN COMPLEX | GLYCOSYLATION | ENV | CRYO-EM STRUCTURE | Buried structures | Inhibitor drugs | Peptides | Envelope protein | Viruses | Trimers | Vaccines | Hydrophobicity | CD4 antigen | Proteins | Disease transmission | Human immunodeficiency virus--HIV | Protein structure | Index Medicus
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7. Full Text Identification of new regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor
by Peachman, Kristina K and Karasavvas, Nicos and Chenine, Agnes-Laurence and McLinden, Robert and Rerks-Ngarm, Supachai and Jaranit, Kaewkungwal and Nitayaphan, Sorachai and Pitisuttithum, Punnee and Tovanabutra, Sodsai and Zolla-Pazner, Susan and Michael, Nelson L and Kim, Jerome H and Alving, Carl R and Rao, Mangala
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0143895 - e0143895
The gut mucosal homing integrin receptor α4β7 present on activated CD4+ T cells interacts with the HIV-1 gp120 second variable loop (V2). Case control analysis... 
Amino Acid Sequence | Cell Line | HIV-1 - metabolism | Humans | Integrins - immunology | CD4-Positive T-Lymphocytes - metabolism | Molecular Sequence Data | Protein Binding - immunology | HIV Envelope Protein gp120 - metabolism | Integrins - metabolism | Case-Control Studies | CD4-Positive T-Lymphocytes - immunology | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | HIV Antibodies - immunology | Immunoglobulin G - immunology | Neutralization Tests - methods | Antibodies, Monoclonal - immunology | HIV Infections - metabolism | Immunoglobulin G - metabolism | Military medicine | MAdCAM-1 antigen | Peptides | Mucosa | Immunoglobulin G | Vaccination | Viruses | Infections | Lymphocytes T | Cell adhesion molecules | Homing | Proteins | Receptors | Lymphocytes | Virions | Human immunodeficiency virus--HIV | Cell adhesion | Armed forces | Inhibition | Binding | Immunoglobulins | Health risks | Blocking | Envelope protein | Glycoproteins | CD4 antigen | Medicine | Hypotheses | Infectious diseases | Monoclonal antibodies | Glycoprotein gp120 | Cell migration | Index Medicus | HIV | Human immunodeficiency virus
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8. Full Text HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART
by Ananworanich, Jintanat and Chomont, Nicolas and Eller, Leigh Ann and Kroon, Eugene and Tovanabutra, Sodsai and Bose, Meera and Nau, Martin and Fletcher, James L.K and Tipsuk, Somporn and Vandergeeten, Claire and O'Connell, Robert J and Pinyakorn, Suteeraporn and Michael, Nelson and Phanuphak, Nittaya and Robb, Merlin L and RV217 & RV254 SEARCH010 Study Grp and RV217 and RV254/SEARCH010 study groups
EBioMedicine, ISSN 2352-3964, 09/2016, Volume 11, Issue C, pp. 68 - 72
HIV DNA is a marker of HIV persistence that predicts HIV progression and remission, but its kinetics in early acute HIV infection (AHI) is poorly understood.... 
Persistence | HIV DNA | Reservoir | Art | Acute HIV infection | MEDICINE, RESEARCH & EXPERIMENTAL | DECAY | SIZE | ANTIRETROVIRAL THERAPY | LEVEL | CD4 CELL COUNT | IMPACT | CURE | LATENT RESERVOIR | DISEASE PROGRESSION | REMISSION | Anti-HIV Agents - pharmacology | HIV Infections - virology | Humans | Proviruses | Genotype | Male | CD4 Lymphocyte Count | Leukocytes, Mononuclear - virology | Viral Load | HIV-1 - classification | Antiretroviral Therapy, Highly Active | Young Adult | HIV-1 - physiology | HIV Infections - diagnosis | RNA, Viral | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | DNA, Viral | Index Medicus
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9. Full Text XProtective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys
by Barouch, Dan H and Stephenson, Kathryn E and Borducchi, Erica N and Smith, Kaitlin and Stanley, Kelly and McNally, Anna G and Liu, Jinyan and Abbink, Peter and Maxfield, Lori F and Seaman, Michael S and Dugast, Anne-Sophie and Alter, Galit and Ferguson, Melissa and Li, Wenjun and Earl, Patricia L and Moss, Bernard and Giorgi, Elena E and Szinger, James J and Eller, Leigh Anne and Billings, Erik A and Rao, Mangala and Tovanabutra, Sodsai and Sanders-Buell, Eric and Weijtens, Mo and Pau, Maria G and Schuitemaker, Hanneke and Robb, Merlin L and Kim, Jerome H and Korber, Bette T and Michael, Nelson L
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 3, p. 531
The global diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development. HIV-1 mosaic antigens are bioinformatically optimized... 
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10. Full Text HIV-1 genetic diversity and demographic characteristics in Bulgaria
by Billings, Erik and Heipertz, Richard A and Varleva, Tonka and Sanders-Buell, Eric and O'Sullivan, Anne Marie and Bose, Meera and Howell, Shana and Kijak, Gustavo H and Taskov, Hristo and Elenkov, Ivailo and Nenova, Marina and Popivanova, Nedialka and Valenzuela, Aimee Bolen and Myles, Otha and Bautista, Christian T and Robb, Merlin L and Michael, Nelson L and Kim, Jerome H and Scott, Paul T and Tovanabutra, Sodsai and Ake, Julie A
PLoS ONE, ISSN 1932-6203, 05/2019, Volume 14, Issue 5, pp. e0217063 - e0217063
HIV-1 strain diversity in Bulgaria is extensive and includes contributions from nearly all major subtypes and the Circulating Recombinant Forms (CRF): 01_AE,... 
Surveys | Medical research | Analysis | Genomics | Medicine, Experimental | Genomes | Phylogeny | HIV (Viruses) | Epidemiology | Biological diversity | Epidemics | Drug abuse | Military medicine | Recombination | Infections | Hybridization | Drug resistance | Risk factors | Gene sequencing | Prevention | Sexually transmitted diseases | Demographics | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Risk assessment | Recombinant | Health risks | Genetic diversity | Risk taking | Risk analysis | Disease control | Control programs | Medicine | Infectious diseases | Hospitals | Men | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
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11. Full Text Neutralization Sensitivity of a Novel HIV-1 CRF01_AE Panel of Infectious Molecular Clones
by Chenine, Agnes-Laurence and Merbah, Melanie and Wieczorek, Lindsay and Molnar, Sebastian and Mann, Brendan and Lee, Jenica and OʼSullivan, Anne-Marie and Bose, Meera and Sanders-Buell, Eric and Kijak, Gustavo H and Herrera, Carolina and McLinden, Robert and OʼConnell, Robert J and Michael, Nelson L and Robb, Merlin L and Kim, Jerome H and Polonis, Victoria R and Tovanabutra, Sodsai
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 07/2018, Volume 78, Issue 3, pp. 348 - 355
BACKGROUND:HIV-1 CRF01_AE is dominant in Thailand where RV144 vaccine trial was conducted. To study immune correlates of protection in ongoing trials,... 
HIV-1 | INFECTIOUS DISEASES | EFFICACY | RHESUS-MONKEYS | infectious molecular clone | RV144 | CLADE | A3R5 | IMMUNOLOGY | THAILAND | TRANSMISSION | CRF01_AE | VACCINE PROTECTION | neutralization assay | ANTIBODY-RESPONSE | EPIDEMIC | SUBTYPE-B | TZM-bl | Construction standards | Sensitivity analysis | Correlation coefficients | Clinical trials | Chronic infection | Viruses | Infections | Vaccines | Pools | Assaying | Molecular chains | Sensitivity | Reporter gene | Infectious diseases | Correlation analysis | Human immunodeficiency virus--HIV | Reagents | Cell lines | Monoclonal antibodies | Neutralization | Infectious Molecular Clone | Neutralization Assay
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12. Full Text New Subtype B Containing HIV-1 Circulating Recombinant of sub-Saharan Africa Origin in Nigerian Men Who Have Sex With Men
by Billings, Erik and Kijak, Gustavo H and Sanders-Buell, Eric and Ndembi, Nicaise and OʼSullivan, Anne Marie and Adebajo, Sylvia and Kokogho, Afoke and Milazzo, Mark and Lombardi, Kara and Baral, Stefan and Nowak, Rebecca and Ramadhani, Habib and Gramzinski, Robert and Robb, Merlin L and Michael, Nelson L and Charurat, Manhattan E and Ake, Julie and Crowell, Trevor A and Tovanabutra, Sodsai and MHRP Viral Sequencing Core and the TRUST/RV368 Study Group and MHRP Viral Sequencing Core and TRUST RV368 Study Grp
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 08/2019, Volume 81, Issue 5, pp. 578 - 584
BACKGROUND:HIV-1 circulating recombinant forms (CRF) containing subtype B are uncommon in sub-Saharan Africa. Prevalent infections observed during enrollment... 
molecular epidemiology | INFECTIOUS DISEASES | INFECTIONS | CRF | MSM | CRYSTAL-STRUCTURE | DNA | DIVERSITY | PREVALENCE | IMMUNOLOGY | Nigeria | Risk groups | Sex | Risk sharing | Infections | Genetic diversity | Vaccines | Phylogeny | Risk analysis | Risk factors | Design optimization | Sexually transmitted diseases | Human immunodeficiency virus--HIV | Phylogenetics | Recombinants | Bayesian analysis | Recombinant
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