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BMJ (Online), ISSN 0959-8146, 2019, Volume 364, pp. l115 - l115
Journal Article
by Zheng, Hou-Feng and Forgetta, Vincenzo and Hsu, Yi-Hsiang and Estrada, Karol and Rosello-Diez, Alberto and Leo, Paul J and Dahia, Chitra L and Park-Min, Kyung Hyun and Tobias, Jonathan H and Kooperberg, Charles and Kleinman, Aaron and Styrkarsdottir, Unnur and Liu, Ching-Ti and Uggla, Charlotta and Evans, Daniel S and Nielson, Carrie M and Walter, Klaudia and Pettersson-Kymmer, Ulrika and Mccarthy, Shane and Eriksson, Joel and Kwan, Tony and Jhamai, Mila and Trajanoska, Katerina and Memari, Yasin and Min, Josine and Huang, Jie and Danecek, Petr and Wilmot, Beth and Li, Rui and Chou, Wen-Chi and Mokry, Lauren E and Moayyeri, Alireza and Claussnitzer, Melina and Cheng, Chia-Ho and Cheung, Warren and Medina-Gómez, Carolina and Ge, Bing and Chen, Shu-Huang and Choi, Kwangbom and Oei, Ling and Fraser, James and Kraaij, Robert and Hibbs, Matthew A and Gregson, Celia L and Paquette, Denis and Hofman, Albert and Wibom, Carl and Tranah, Gregory J and Marshall, Mhairi and Gardiner, Brooke B and Cremin, Katie and Auer, Paul and Hsu, Li and Ring, Sue and Tung, Joyce Y and Thorleifsson, Gudmar and Enneman, Anke W and van Schoor, Natasja M and de Groot, Lisette C. P. G. M and van der Velde, Nathalie and Melin, Beatrice and Kemp, John P and Christiansen, Claus and Sayers, Aian and Zhou, Yanhua and Calderari, Sophie and van Rooij, Jeroen and Carlson, Chris and Peters, Ulrike and Berlivet, Soizik and Dostie, Josée and Uitterlinden, Ane G and Williams, Stephen R and Farber, Charles and Grinberg, Daniel and LaCroix, Anea Z and Haessler, Jeff and Chasman, Daniel I and Giulianini, Franco and Rose, Lynda M and Ridker, Paul M and Eisman, John A and Nguyen, Tuan V and Center, Jacqueline R and Nogues, Xavier and Garcia-Giralt, Natalia and Launer, Lenore L and Gudnason, Vilmunder and Mellström, Dan and Vandenput, Liesbeth and Amin, Najaf and van Duijn, Cornelia M and Karlsson, Magnus K and Ljunggren, Östen and Svensson, Olle and Hallmans, Göran and Rousseau, François and Giroux, Sylvie and Bussière, Johanne and Arp, Pascal P and ... and AOGC Consortium and UK10K Consortium and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Umeå universitet and Institutionen för folkhälsa och klinisk medicin and Institutionen för farmakologi och klinisk neurovetenskap and Farmakologi and Enheten för biobanksforskning and Näringsforskning and Institutionen för kirurgisk och perioperativ vetenskap
Nature, ISSN 0028-0836, 2015, Volume 526, Issue 7571, pp. 112 - +
The extent to which low-frequency (minor allele frequency (MAF) between 1-5%) and rare (MAF <= 1%) variants contribute to complex traits and disease in the... 
WIDE ASSOCIATION LOCI | MINERAL DENSITY | METAANALYSIS | VARIANTS | GENE | ENGRAILED-1 | MULTIDISCIPLINARY SCIENCES | MOUSE | HUMAN-DISEASES | COMPLEX TRAITS | OSTEOPOROSIS | European Continental Ancestry Group - genetics | Gene Frequency - genetics | Genetic Predisposition to Disease - genetics | Genomics | Humans | Genotype | Bone Density - genetics | Sequence Analysis, DNA | Europe - ethnology | Fractures, Bone - genetics | Genome, Human - genetics | Homeodomain Proteins - genetics | Exome - genetics | Animals | Wnt Proteins - genetics | Bone and Bones - metabolism | Female | Genetic Variation - genetics | Mice | Disease Models, Animal | Quantitative trait loci | Fractures | Bones | Genetic aspects | Nucleotide sequencing | Identification and classification | Density | Methods | DNA sequencing | Proteins | Studies | Osteoporosis | Ethnicity | Population | Bone density | Genomes | Neck | Meta-analysis | Index Medicus | Malalties | Aspectes genètics | Ossos | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences | HNE Voeding en Gezondheid in de Levenscyclus | Wereldvoeding | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Health over the Lifecourse
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2017, Volume 49, Issue 10, pp. 1468 - 1475
Osteoporosis is a common disease diagnosed primarily by measurement of bone mineral density (BMD). We undertook a genomewide association study (GWAS) in... 
METAANALYSIS | MOUSE | GENETICS & HEREDITY | RISK | QUANTITATIVE ULTRASOUND | OLDER WOMEN | MENDELIAN RANDOMIZATION | LD SCORE REGRESSION | HIGH-TRAUMA FRACTURES | GENOME-WIDE ASSOCIATION | GENE-FUNCTION | Calcaneus - pathology | Glypicans - deficiency | Humans | Male | Bone Density - genetics | Gene Expression Profiling | Osteochondrodysplasias - genetics | Female | Osteoporosis - genetics | Disease Models, Animal | Femur - chemistry | Genome-Wide Association Study | Glypicans - physiology | Osteocytes - metabolism | Molecular Sequence Annotation | Glypicans - genetics | Osteoclasts - metabolism | Mice, Knockout | Phenotype | Animals | Osteoporosis - pathology | Osteochondrodysplasias - congenital | Mice | Polymorphism, Single Nucleotide | Growth Disorders - genetics | Osteoblasts - metabolism | Osteoporosis | Genome-wide association studies | Bones | Genetic aspects | Single nucleotide polymorphisms | Health aspects | Density | Risk factors | Methods | Genes | Genomics | Osteocytes | Genomes | Single-nucleotide polymorphism | Gene expression | Osteoblasts | Loci | Studies | Consortia | Ultrasonic imaging | Phenotyping | Biocompatibility | Osteoclasts | Bone mineral density | Gene loci | Bone density | Bone | Bioinformatics | Ultrasound | Index Medicus | bone mineral density | genome-wide association | osteoporosis | GPC6 | UK Biobank | ultrasound
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, pp. e0129116 - e0129116
Journal Article
by Trajanoska, Katerina and Morris, John A and Oei, Ling and Zheng, Hou-Feng and Evans, David M and Kiel, Douglas P and Ohlsson, Claes and Richards, J. Brent and Rivadeneira, Fernando and Forgett, V and Leong, A and Ahmad, O.S and Laurin, C and Mokry, L.E and Ross, S and Elks, C.E and Bowden, J and Warrington, N.M and Kleinman, A and Willems, S.M and Wright, D and Day, F.R and Murray, A and Ruth, K.S and Tsilidis, K.K and Ackert-Bicknell, C.L and Bassett, J.H.D and van der Eerden, B.C.J and Gautvik, K and Reppe, S and Williams, G.R and Medina-Gómez, C and Estrada, K and Amin, N and Bis, J.C and Breda, S and Chasman, Chasman and Demissie, S and Enneman, A.W and Hsu, Y.H and Ingvarsson, T and Kähönen, M and Kammerer, C and Lacroix, A.Z and Li, G and Liu, C.T and Liu, Y and Lorentzon, M and Mägi, R and Mihailov, E and Mlani, L and Moayyeri, A and Nielson, C.M and Nerea, A and Sham, P.C and Siggeirsdotir, K and Sigurdsson, G and Thorsteinsdottir, U and Trompet, S and Thorleifsson, G and Vandenput, L and van der Velde, N and Viikari, J and Xiao, S.M and Hua Zhao, J and Akesson, K.E and Andersen, M and Atanasovska, B and Balcells, S and Eriksson, J and Formosa, M.M and Garcia-Ibarbia, C and Gonzalez-Macias, J and Garcia-Giralt, N and Hallmans, G and Karlsson, M and Khusainova, R and Kim, Kim and Lee, S.H and Leung, P.C and Mallmin, H and Kwok, T.C.Y and Masi, L and Melin, B.S and Mencej-Bedrac, S and Nethander, M and Olmos, J.M and Kollia, P and Prezelj, J and Van Schoor, Schoor and Svensson, O and Szulc, P and Valero, C and Woo, J and Brandi, M and Cheng, S and Chapurlat, R and Christiansen, C and Cooper, C and Dedoussis, G and ... and GEFOS GENOMOS Consortium and 23andMe Res Team and GEFOS/GENOMOS consortium and the 23andMe research team and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för kirurgiska vetenskaper
BMJ (Online), ISSN 0959-8146, 2018, Volume 362, pp. k3225 - k3225
Journal Article
Nature Communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, pp. 16015 - 16015
textabstractHand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause... 
SKELETAL-MUSCLE | METAANALYSIS | VARIANTS | GROWTH-FACTOR-ALPHA | MULTIDISCIPLINARY SCIENCES | DISEASE | FRACTURES | GENETIC INFLUENCES | MENDELIAN RANDOMIZATION | INSTRUMENTS | GENOME-WIDE ASSOCIATION | Genetics, Population | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Membrane Proteins - genetics | Humans | Middle Aged | Repressor Proteins - genetics | Male | United Kingdom | Genetic Loci | Transforming Growth Factor alpha - genetics | Actins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Hand - physiology | Hand Strength | Cohort Studies | Mortality | Disorders | Product design | Genetic diversity | Loci | Skeletal muscle | Wrist | Signal transduction | Psychomotor performance | Transduction | Grip strength | Muscular strength | Age | Fitness | Structure-function relationships | Index Medicus | Genetik | Basic Medicine | Medical Genetics | Medicinsk genetik | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Genetics | Natural Sciences | HNE Voeding en Gezondheid in de Levenscyclus | Wereldvoeding | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Health over the Lifecourse
Journal Article
by Morris, John A and Kemp, John P and Youlten, Scott E and Laurent, Laetitia and Logan, John G and Chai, Ryan C and Vulpescu, Nicholas A and Forgetta, Vincenzo and Kleinman, Aaron and Mohanty, Sindhu T and Sergio, C. Marcelo and Quinn, Julian and Nguyen-Yamamoto, Loan and Luco, Aimee-Lee and Vijay, Jinchu and Simon, Marie-Michelle and Pramatarova, Albena and Medina-Gomez, Carolina and Trajanoska, Katerina and Ghirardello, Elena J and Butterfield, Natalie C and Curry, Katharine F and Leitch, Victoria D and Sparkes, Penny C and Adoum, Anne-Tounsia and Mannan, Naila S and Komla-Ebri, Davide S. K and Pollard, Andrea S and Dewhurst, Hannah F and Hassall, Thomas A. D and Beltejar, Michael-John G and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and McCreight, Jennifer C and Huber, Karen E and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Noblin, Elizabeth S and Northover, Carrie A. M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Adams, Douglas J and Vaillancourt, Suzanne M and Kaptoge, Stephen and Baldock, Paul and Cooper, Cyrus and Reeve, Jonathan and Ntzani, Evangelia E and Evangelou, Evangelos and Ohlsson, Claes and Karasik, David and Rivadeneira, Fernando and Kiel, Douglas P and Tobias, Jonathan H and Gregson, Celia L and Harvey, Nicholas C and Grundberg, Elin and Goltzman, David and Adams, David J and Lelliott, Christopher J and Hinds, David A and Ackert-Bicknell, Cheryl L and Hsu, Yi-Hsiang and Maurano, Matthew T and Croucher, Peter I and Williams, Graham R and Bassett, J. H. Duncan and Evans, David M and Richards, J. Brent and 23 Me Res Team and 23andMe Research Team
Nature Genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 258 - 266
Journal Article