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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 607 - 620.e15
Background Patients with heterozygous germline mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) experience autoimmunity and lymphoid... 
Allergy and Immunology | PHTS | autoimmunity | immunologic synapse | PTEN | Regulatory T cells | phosphatases | phosphoinositide 3-kinase | PH domain leucine-rich repeat protein phosphatase | HOMEOSTASIS | PROTEIN | KINASE | PROMOTER MUTATIONS | RILEY-RUVALCABA-SYNDROME | IMMUNOLOGY | ALLERGY | RESOLUTION MELTING ANALYSIS | AKT-MTOR | LYMPHOID HYPERPLASIA | EXPRESSION | Autoimmunity | Humans | Hyperplasia | Middle Aged | Phosphoprotein Phosphatases - metabolism | Male | Immunological Synapses - metabolism | Young Adult | Forkhead Transcription Factors - metabolism | Membrane Potential, Mitochondrial | Adult | Child | Hamartoma Syndrome, Multiple - immunology | Lymphocyte Subsets - physiology | T-Lymphocytes, Regulatory - physiology | PTEN Phosphohydrolase - genetics | Hamartoma Syndrome, Multiple - genetics | Signal Transduction | Cells, Cultured | B-Lymphocytes - physiology | PTEN Phosphohydrolase - metabolism | Nuclear Proteins - metabolism | Mutation - genetics | Protein Transport | Adolescent | Protein Binding | Aged | Medical colleges | Care and treatment | Phosphatases | Gene mutations | Analysis | Children's hospitals | Genomics | Medical genetics | Genetic research | T cells | Tumors | Hamartoma | Proteins | Blood & organ donations | Hematology | Biopsy | Lymphocytes | T cell receptors | Mutation | Kinases | Metabolism | Phosphatase | FACS, Fluorescence-activated cell sorting | TCR, T-cell receptor | mTOR complex 1 | NHERF1, Na+ | H+-exchanger 3 regulatory factor | MALT, Mucosa-associated lymphoid tissue | APC, Allophycocyanin | SHIP, Src homology domain 2–containing inositol phosphatase | HRM, High Resolution DNA Melting | FITC, Fluorescein isothiocyanate | PP2A, Protein phosphatase 2A | mTORC1, PTEN | PHTS, PTEN hamartoma tumor syndrome | PerCP, Peridinin-chlorophyll-protein complex | CS, Cowden syndrome | POD, Peroxidase | Tmem, Memory T | TMRE, Tetramethylrhodamine-ethylester | Immune Deficiencies, Infection, and Systemic Immune Disorders | IC50, Inhibitory concentration of 50 | CTLA-4, Cytotoxic T lymphocyte–associated antigen 4 | PHLPP, PH domain leucine-rich repeat protein phosphatase | AKT | DLG1, Scaffold protein discs, large homolog 1 | FOXP3, Forkhead box P3 | ICAM-1, Intercellular adhesion molecule 1 | iTreg, In vitro induced regulatory T | PE, Phycoerythrin | PI3K, Phosphoinositide 3-kinase | mTOR, Mammalian target of rapamycin | PTEN, Phosphatase and tensin homologue deleted on chromosome 10
Journal Article
by Wood, Angela M and Kaptoge, Stephen and Butterworth, Adam S and Butterworth, Adam and Willeit, Peter and Warnakula, Samantha and Bolton, Thomas and Paige, Ellie and Paul, Dirk S and Sweeting, Michael and Burgess, Stephen and Bell, Steven and Astle, William and Stevens, David and Koulman, Albert and Selmer, Randi M and Verschuren, Monique and Verschuren, W M Monique and Sato, Shinichi and Njølstad, Inger and Woodward, Mark and Salomaa, Veikko and Nordestgaard, Børge G and Yeap, Bu B and Fletcher, Astrid and Melander, Olle and Kuller, Lewis H and Balkau, Beverley and Marmot, Michael and Koenig, Wolfgang and Casiglia, Edoardo and Cooper, Cyrus and Cooper, Jackie A and Arndt, Volker and Franco, Oscar H and Wennberg, Maria and Wennberg, Patrik and Gallacher, John and de la Cámara, Agustín Gómez and Völzke, Henry and Dahm, Christina C and Dale, Caroline E and Bergmann, Manuela M and Bergmann, Manuela and Crespo, Carlos J and Crespo, Carlos and van der Schouw, Yvonne T and Kaaks, Rudolf and Simons, Leon A and Lagiou, Pagona and Schoufour, Josje D and Boer, Jolanda M A and Boer, Jolanda M.A and Key, Timothy J and Rodriguez, Beatriz and Rodriguez, Carlos J and Moreno-Iribas, Conchi and Davidson, Karina W and Taylor, James O and Sacerdote, Carlotta and Wallace, Robert B and Quiros, J Ramon and Quiros, J. Ramon and Tumino, Rosario and Blazer, Dan G and Linneberg, Allan and Daimon, Makoto and Panico, Salvatore and Howard, Barbara and Skeie, Guri and Strandberg, Timo and Weiderpass, Elisabete and Nietert, Paul J and Psaty, Bruce M and Kromhout, Daan and Salamanca-Fernandez, Elena and Kiechl, Stefan and Krumholz, Harlan M and Grioni, Sara and Palli, Domenico and Huerta, José M and Price, Jackie and Sundström, Johan and Arriola, Larraitz and Arima, Hisatomi and Travis, Ruth C and Panagiotakos, Demosthenes B and Karakatsani, Anna and Trichopoulou, Antonia and Kühn, Tilman and Grobbee, Diederick E and Barrett-Connor, Elizabeth and van Schoor, Natasja and Boeing, Heiner and Overvad, Kim and Kauhanen, Jussi and Wareham, Nick and Langenberg, Claudia and Forouhi, Nita and Després, Jean-Pierre and ... and Emerging Risk Factors Collabora and Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Näringsforskning and Umeå universitet
The Lancet, ISSN 0140-6736, 04/2018, Volume 391, Issue 10129, pp. 1513 - 1523
Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk... 
MORTALITY | STROKE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | CHOLESTEROL | PATTERN | CARDIOVASCULAR-DISEASE | CORONARY-HEART-DISEASE | ASSOCIATION | CANCER | BLOOD-PRESSURE | Cardiovascular Diseases - etiology | Prospective Studies | Humans | Middle Aged | Female | Male | Alcohol Drinking - adverse effects | Alcohol Drinking - mortality | Drinking of alcoholic beverages | Myocardial infarction | Heart attacks | Sex | Income | Cardiovascular disease | Dosage | Risk factors | Guidelines | Alcohol use | Aorta | Heart diseases | Age | Consumption | Medical research | Cerebral infarction | Data analysis | Stroke | Life expectancy | Risk groups | Thresholds | Drinking behavior | Mortality | Diabetes mellitus | Health risks | Data processing | Risk analysis | Disease control | Cholesterol | Studies | Lipoproteins | Life span | Collaboration | Alcoholic beverages | Infarction | Diabetes | Cardiovascular diseases | Health risk assessment | Smoking | Community medicine, Social medicine: 801 | Samfunnsmedisin, sosialmedisin: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Medical and Health Sciences | Medicin och hälsovetenskap | Beroendelära | Public Health, Global Health, Social Medicine and Epidemiology | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Substance Abuse | Health Sciences | Human Nutrition & Health | Human Nutrition | Afdeling Humane voeding | Humane Voeding | Humane Voeding & Gezondheid | Human Nutrition (HNE)
Journal Article
by Majounie, Elisa, PhD and Renton, Alan E, PhD and Mok, Kin, MSc and Dopper, Elise GP and Waite, Adrian, PhD and Rollinson, Sara, PhD and Chiò, Adriano, MD and Restagno, Gabriella, MD and Nicolaou, Nayia, MSc and Simon-Sanchez, Javier, PhD and van Swieten, John C, Prof and Abramzon, Yevgeniya and Johnson, Janel O, PhD and Sendtner, Michael, Prof and Pamphlett, Roger, MD and Orrell, Richard W, MD and Mead, Simon, MD and Sidle, Katie C, MD and Houlden, Henry, Prof and Rohrer, Jonathan D, MD and Morrison, Karen E, Prof and Pall, Hardev, MD and Talbot, Kevin, Prof and Ansorge, Olaf, MD and Hernandez, Dena G, MSc and Arepalli, Sampath, MS and Sabatelli, Mario, MD and Mora, Gabriele, MD and Corbo, Massimo, MD and Giannini, Fabio, MD and Calvo, Andrea, MD and Englund, Elisabet, MD and Borghero, Giuseppe, MD and Floris, Gian Luca, MD and Remes, Anne M, Prof and Laaksovirta, Hannu, MD and McCluskey, Leo, MD and Trojanowski, John Q, Prof and Van Deerlin, Vivianna M, MD and Schellenberg, Gerard D, Prof and Nalls, Michael A, PhD and Drory, Vivian E, MD and Lu, Chin-Song, Prof and Yeh, Tu-Hsueh, MD and Ishiura, Hiroyuki, MD and Takahashi, Yuji, MD and Tsuji, Shoji, Prof and Le Ber, Isabelle, MD and Brice, Alexis, Prof and Drepper, Carsten, PhD and Williams, Nigel, PhD and Kirby, Janine, PhD and Shaw, Pamela, Prof and Hardy, John, Prof and Tienari, Pentti J, MD and Heutink, Peter, Prof and Morris, Huw R, MD and Pickering-Brown, Stuart, Prof and Traynor, Bryan J, Dr and Chromosome 9-ALS FTD Consortium and French Res Network FTLD FTLD ALS and ITALSGEN Consortium and French research network on FTLD/FTLD/ALS and Chromosome 9-ALS/FTD Consortium and Oncology and Pathology, Kamprad Lab and Lund University and Lunds universitet and Onkologi och Patologi, Kampradlab
Lancet Neurology, The, ISSN 1474-4422, 2012, Volume 11, Issue 4, pp. 323 - 330
Summary Background We aimed to accurately estimate the frequency of a hexanucleotide repeat expansion in C9orf72 that has been associated with a large... 
Neurology | PREVALENCE | MUTATIONS | LOBAR DEGENERATION | GENETICS | TDP-43 | CLINICAL NEUROLOGY | Frontotemporal Dementia - genetics | Cross-Sectional Studies | DNA Repeat Expansion - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Child, Preschool | Genotype | Male | Genetic Loci | Open Reading Frames - genetics | Young Adult | Chromosomes, Human, Pair 9 - genetics | Adolescent | Age of Onset | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Medical research | Medical colleges | Care and treatment | Nervous system diseases | Neurosciences | Molecular genetics | Oncology, Experimental | Questions and answers | Amyotrophic lateral sclerosis | Research | Medicine, Experimental | Agriculture | Physicians (General practice) | Alzheimer's disease | Dementia | Cancer | Biomedical engineering | Haplotypes | Polymerase chain reaction | Neurodegenerative diseases | Ethnic groups | Data processing | Mutation | Frontotemporal dementia | Genetic counselling | Islands | Age | Toll-Like Receptor 4 | Open Reading Frames | Adaptor Proteins, Vesicular Transport | Lipopolysaccharides | Life Sciences | DNA Repeat Expansion | Interferon Regulatory Factor-3 | Transfection | Amyotrophic Lateral Sclerosis | RNA Interference | HEK293 Cells | Membrane Glycoproteins | Vesicular Transport Proteins | Protein Structure, Tertiary | Cell Line | Chemokine CCL5 | Frontotemporal Dementia | Signal Transduction | Myeloid Differentiation Factor 88 | Chromosomes, Human, Pair 9 | Protein Transport | Adaptor Proteins, Signal Transducing | Santé publique et épidémiologie | RNA, Small Interfering | Endosomes | Neurologi | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 86, Issue 4, pp. 694 - 701
Journal Article
Journal of Shoulder and Elbow Surgery, ISSN 1058-2746, 2017, Volume 26, Issue 5, pp. 902 - 908
Background Straight antegrade intramedullary nailing of proximal humerus fractures has shown promising clinical results. However, up to 36% of all humeri seem... 
Orthopedics | proximal anchoring point | fifth anchoring point | osteoporotic fracture | straight antegrade humeral nailing | entry point | Proximal humerus fracture
Journal Article
The Lancet, ISSN 0140-6736, 12/2017, Volume 390, Issue 10114, pp. 2779 - 2789
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