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by Carbone, Marco and Sharp, Stephen J and Flack, Steve and Paximadas, Dimitrios and Spiess, Kelly and Adgey, Carolyn and Griffiths, Laura and Lim, Reyna and Trembling, Paul and Williamson, Kate and Wareham, Nick J and Aldersley, Mark and Bathgate, Andrew and Burroughs, Andrew K and Heneghan, Michael A and Neuberger, James M and Thorburn, Douglas and Hirschfield, Gideon M and Cordell, Heather J and Alexander, Graeme J and Jones, David E.J and Sandford, Richard N and Mells, George F and Jones, David and Kirby, John and Hirschfield, Gideon and Alexander, Graeme and Sandford, Richard and Taylor‐Robinson, Simon and Ch'ng, Chin Lye and Rahman, Mesbah and Yapp, Tom and Sturgess, Richard and Healey, Christopher and Czajkowski, Marek and Gunasekera, Anton and Gyawali, Pranab and Premchand, Purushothaman and Kapur, Kapil and Marley, Richard and Foster, Graham and Watson, Alan and Dias, Aruna and Subhani, Javaid and Harvey, Rory and McCorry, Roger and Ramanaden, David and Gasem, Jaber and Evans, Richard and Mathialahan, Thiriloganathan and Shorrock, Christopher and Lipscomb, George and Southern, Paul and Tibble, Jeremy and Gorard, David and Palegwala, Altaf and Jones, Susan and Dawwas, Mohamed and Dolwani, Sunil and Prince, Martin and Foxton, Matthew and Elphick, David and Mitchison, Harriet and Gooding, Ian and Karmo, Mazn and Saksena, Sushma and Mendall, Mike and Patel, Minesh and Ede, Roland and Austin, Andrew and Sayer, Joanna and Hankey, Lorraine and Hovell, Christopher and Fisher, Neil and Carter, Martyn and Koss, Konrad and Piotrowicz, Andrzej and Grimley, Charles and Neal, David and Lim, Guan and Levi, Sass and Ala, Aftab and Broad, Andrea and Saeed, Athar and Wood, Gordon and Brown, Jonathan and Wilkinson, Mark and Gordon, Harriet and Ramage, John and Ridpath, Jo and Ngatchu, Theodore and Grover, Bob and Shaukat, Syed and Shidrawi, Ray and Abouda, George and Ali, Faiz and Rees, Ian and Salam, Imroz and Narain, Mark and Brown, Ashley and ... and UK-PBC Consortium
Hepatology, ISSN 0270-9139, 03/2016, Volume 63, Issue 3, pp. 930 - 950
Journal Article
Journal of Hepatology, ISSN 0168-8278, 08/2019, Volume 71, Issue 2, pp. 371 - 378
[Display omitted] •Established blood tests can be used in primary care to stratify patients with fatty liver disease.•A 2-step pathway (FIB-4 followed by ELF™... 
Cirrhosis | NAFLD | Clinical management | Cost effectiveness | Steatohepatitis | FIB-4 | Non-invasive fibrosis test | ELF | MORTALITY | STAGE | RISK | OBESITY | NONINVASIVE MARKERS | ADVANCED FIBROSIS | GASTROENTEROLOGY & HEPATOLOGY | Liver diseases | Fatty liver | Blood tests | Fibrosis | Primary care | Alcohol use
Journal Article
World journal of gastroenterology, ISSN 1007-9327, 01/2020, Volume 26, Issue 2, pp. 109 - 133
At present chronic liver disease (CLD), the third commonest cause of premature death in the United Kingdom is detected late, when interventions are... 
Anti-fibrotic | Cirrhosis | Biomarker | Chronic hepatitis C | Fibrosis | Review | Chronic liver disease | Non-alcoholic fatty liver disease | Liver inflammation
Journal Article
European Journal of Gastroenterology & Hepatology, ISSN 0954-691X, 11/2016, Volume 29, Issue 3, pp. 289 - 296
AIMThe utility of noninvasive serum markers to longitudinally monitor liver fibrosis is not established. METHODSA total of 70 patients with chronic hepatitis C... 
silymarin | histology | chronic hepatitis C | fibrosis | biomarker | interferon | longitudinal | UNITED-STATES | TESTS | CHRONIC HEPATITIS-C | BIOPSY | ELASTOGRAPHY | ACCURACY | CIRRHOSIS | VALIDATED PREDICTOR | INFECTION | GASTROENTEROLOGY & HEPATOLOGY | Liver - virology | Recombinant Proteins - therapeutic use | Predictive Value of Tests | Liver - pathology | Prospective Studies | Humans | Middle Aged | Hepacivirus - genetics | Male | Polyethylene Glycols - therapeutic use | Viral Load | Young Adult | Austria | Liver - drug effects | Time Factors | Hyaluronic Acid - blood | Antiviral Agents - therapeutic use | Liver - metabolism | Genotype | Liver Cirrhosis - blood | Procollagen - blood | Biomarkers - blood | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Antiviral Agents - adverse effects | Adolescent | Germany | Area Under Curve | Polyethylene Glycols - adverse effects | RNA, Viral - blood | Recombinant Proteins - adverse effects | Peptide Fragments - blood | Adult | Female | Drug Therapy, Combination | Tissue Inhibitor of Metalloproteinase-1 - blood | Hepacivirus - drug effects | Liver Cirrhosis - drug therapy | Silymarin - therapeutic use | Liver Cirrhosis - diagnosis | Silymarin - adverse effects | Interferon-alpha - therapeutic use | Treatment Outcome | Hepatitis C, Chronic - blood | Liver Cirrhosis - virology | Biopsy | ROC Curve | Aged | Interferon-alpha - adverse effects
Journal Article
01/2019
Chronic liver disease (CLD) is a major cause of death in the UK. The major contributors are alcohol, fat and viral hepatitis. The common pathway towards... 
Dissertation
2019
Chronic liver disease (CLD) is a major cause of death in the UK. The major contributors are alcohol, fat and viral hepatitis. The common pathway towards... 
Dissertation
Expert Review of Anti-infective Therapy, ISSN 1478-7210, 03/2012, Volume 10, Issue 3, pp. 269 - 279
Journal Article
Expert Opinion on Investigational Drugs, ISSN 1354-3784, 08/2012, Volume 21, Issue 8, pp. 1193 - 1209
Journal Article
Frontline Gastroenterology, ISSN 2041-4137, 07/2019, p. flgastro-2019-101221
A 60-year-old male liver transplant recipient presented to his local hospital with left-sided partial seizures following a few days of generalised headache. He... 
Journal Article
Nature Genetics, ISSN 1061-4036, 01/1999, Volume 21, Issue 1, pp. 76 - 83
Journal Article