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Journal of the American College of Cardiology, ISSN 0735-1097, 2010, Volume 55, Issue 15, pp. 1611 - 1618
Journal Article
by Tragante, Vinicius and Barnes, Michael R and Ganesh, Santhi K and Lanktree, Matthew B and Guo, Wei and Franceschini, Nora and Smith, Erin N and Johnson, Toby and Holmes, Michael V and Padmanabhan, Sandosh and Karczewski, Konrad J and Almoguera, Berta and Barnard, John and Baumert, Jens and Chang, Yen-Pei Christy and Elbers, Clara C and Farrall, Martin and Fischer, Mary E and Gaunt, Tom R and Gho, Johannes M.I.H and Gieger, Christian and Goel, Anuj and Gong, Yan and Isaacs, Aaron and Kleber, Marcus E and Leach, Irene Mateo and McDonough, Caitrin W and Meijs, Matthijs F.L and Melander, Olle and Nelson, Christopher P and Nolte, Ilja M and Pankratz, Nathan and Price, Tom S and Shaffer, Jonathan and Shah, Sonia and Tomaszewski, Maciej and van der Most, Peter J and Van Iperen, Erik P.A and Vonk, Judith M and Witkowska, Kate and Wong, Caroline O.L and Zhang, Li and Beitelshees, Amber L and Berenson, Gerald S and Bhatt, Deepak L and Brown, Morris and Burt, Amber and Cooper-DeHoff, Rhonda M and Connell, John M and Cruickshanks, Karen J and Curtis, Sean P and Davey-Smith, George and Delles, Christian and Gansevoort, Ron T and Guo, Xiuqing and Haiqing, Shen and Hastie, Claire E and Hofker, Marten H and Hovingh, G. Kees and Kim, Daniel S and Kirkland, Susan A and Klein, Barbara E and Klein, Ronald and Li, Yun R and Maiwald, Steffi and Newton-Cheh, Christopher and O’Brien, Eoin T and Onland-Moret, N. Charlotte and Palmas, Walter and Parsa, Afshin and Penninx, Brenda W and Pettinger, Mary and Vasan, Ramachandran S and Ranchalis, Jane E and M Ridker, Paul and Rose, Lynda M and Sever, Peter and Shimbo, Daichi and Steele, Laura and Stolk, Ronald P and Thorand, Barbara and Trip, Mieke D and van Duijn, Cornelia M and Verschuren, W. Monique and Wijmenga, Cisca and Wyatt, Sharon and Young, J. Hunter and Zwinderman, Aeilko H and Bezzina, Connie R and Boerwinkle, Eric and Casas, Juan P and Caulfield, Mark J and Chakravarti, Aravinda and Chasman, Daniel I and Davidson, Karina W and Doevendans, Pieter A and Dominiczak, Anna F and FitzGerald, Garret A and Gums, John G and Fornage, Myriam and ...
American journal of human genetics, ISSN 0002-9297, 2014, Volume 94, Issue 3, pp. 349 - 360
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2008, Volume 358, Issue 14, pp. 1431 - 1443
.... Visseren, M.D., Ph.D., Eric J.G. Sijbrands, M.D., Ph.D., Mieke D. Trip, M.D., Ph.D., Evan A. Stein, M.D., Ph.D., Daniel Gaudet, M.D., Ph.D., Raphael Duivenvoorden, M.D... 
INTIMA-MEDIA THICKNESS | REDUCING CHOLESTEROL | MEDICINE, GENERAL & INTERNAL | HIGH-DOSE ATORVASTATIN | CAROTID ATHEROSCLEROSIS | MYOCARDIAL-INFARCTION | DOUBLE-BLIND | ENDOTHELIAL FUNCTION | ARTERIAL-WALL THICKNESS | SECONDARY PREVENTION | ATHEROSCLEROSIS PROGRESSION | Femoral Artery - pathology | Simvastatin - therapeutic use | Tunica Media - pathology | Simvastatin - adverse effects | Cholesterol - blood | Humans | Middle Aged | Ezetimibe | Male | Hyperlipoproteinemia Type II - pathology | Ultrasonography | Adult | Cholesterol, LDL - blood | Female | Tunica Intima - diagnostic imaging | Hyperlipoproteinemia Type II - drug therapy | Drug Therapy, Combination | Double-Blind Method | Azetidines - adverse effects | Treatment Outcome | Anticholesteremic Agents - adverse effects | Tunica Media - diagnostic imaging | Anticholesteremic Agents - therapeutic use | Carotid Arteries - diagnostic imaging | Femoral Artery - diagnostic imaging | Tunica Intima - pathology | Azetidines - therapeutic use | Triglycerides - blood | Carotid Arteries - pathology | Proteolipids | Care and treatment | Lipoproteins | Hypercholesterolemia | Atherosclerosis | Research | Blood lipoproteins | Health aspects | Diet | Cardiovascular disease | Cholesterol | Statins | Veins & arteries | Ambulatory care | Index Medicus | Abridged Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 10, p. e25946
Journal Article
by Asselbergs, Folkert W and Guo, Yiran and van Iperen, Erik P.A and Sivapalaratnam, Suthesh and Tragante, Vinicius and Lanktree, Matthew B and Lange, Leslie A and Almoguera, Berta and Appelman, Yolande E and Barnard, John and Baumert, Jens and Beitelshees, Amber L and Bhangale, Tushar R and Chen, Yii-Der Ida and Gaunt, Tom R and Gong, Yan and Hopewell, Jemma C and Johnson, Toby and Kleber, Marcus E and Langaee, Taimour Y and Li, Mingyao and Li, Yun R and Liu, Kiang and McDonough, Caitrin W and Meijs, Matthijs F.L and Middelberg, Rita P.S and Musunuru, Kiran and Nelson, Christopher P and O’Connell, Jeffery R and Padmanabhan, Sandosh and Pankow, James S and Pankratz, Nathan and Rafelt, Suzanne and Rajagopalan, Ramakrishnan and Romaine, Simon P.R and Schork, Nicholas J and Shaffer, Jonathan and Shen, Haiqing and Smith, Erin N and Tischfield, Sam E and van der Most, Peter J and van Vliet-Ostaptchouk, Jana V and Verweij, Niek and Volcik, Kelly A and Zhang, Li and Bailey, Kent R and Bailey, Kristian M and Bauer, Florianne and Boer, Jolanda M.A and Braund, Peter S and Burt, Amber and Burton, Paul R and Buxbaum, Sarah G and Chen, Wei and Cooper-DeHoff, Rhonda M and Cupples, L. Adrienne and deJong, Jonas S and Delles, Christian and Duggan, David and Fornage, Myriam and Furlong, Clement E and Glazer, Nicole and Gums, John G and Hastie, Claire and Holmes, Michael V and Illig, Thomas and Kirkland, Susan A and Kivimaki, Mika and Klein, Ronald and Klein, Barbara E and Kooperberg, Charles and Kottke-Marchant, Kandice and Kumari, Meena and LaCroix, Andrea Z and Mallela, Laya and Murugesan, Gurunathan and Ordovas, Jose and Ouwehand, Willem H and Post, Wendy S and Saxena, Richa and Scharnagl, Hubert and Schreiner, Pamela J and Shah, Tina and Shields, Denis C and Shimbo, Daichi and Srinivasan, Sathanur R and Stolk, Ronald P and Swerdlow, Daniel I and Taylor, Herman A and Topol, Eric J and Toskala, Elina and van Pelt, Joost L and van Setten, Jessica and Yusuf, Salim and Whittaker, John C and Zwinderman, A.H and Anand, Sonia S and Balmforth, Anthony J and Berenson, Gerald S and Bezzina, Connie R and ... and LifeLines Cohort Study
American journal of human genetics, ISSN 0002-9297, 2012, Volume 91, Issue 5, pp. 823 - 838
Journal Article
by Holmes, Michael V., MSc and Simon, Tabassome, MD, PhD and Exeter, Holly J., PhD and Folkersen, Lasse, PhD and Asselbergs, Folkert W., MD, PhD and Guardiola, Montse, PhD and Cooper, Jackie A., MSc and Palmen, Jutta, MSc and Hubacek, Jaroslav A., DSc, PhD and Carruthers, Kathryn F., MPhil and Horne, Benjamin D., PhD, MPH and Brunisholz, Kimberly D., MST and Mega, Jessica L., MD, MPH and van Iperen, Erik P.A., MSc and Li, Mingyao, PhD and Leusink, Maarten, MSc and Trompet, Stella, PhD and Verschuren, Jeffrey J.W., MD, MSc and Hovingh, G. Kees, MD, PhD and Dehghan, Abbas, MD, PhD and Nelson, Christopher P., PhD and Kotti, Salma, PharmD, PhD and Danchin, Nicolas, MD, PhD and Scholz, Markus, PhD and Haase, Christiane L., PhD and Rothenbacher, Dietrich, MD and Swerdlow, Daniel I., MBBS, PhD and Kuchenbaecker, Karoline B., Dipl Psych, MSc and Staines-Urias, Eleonora, MD, MSc and Goel, Anuj, MSc and van 't Hooft, Ferdinand, MD, PhD and Gertow, Karl, PhD and de Faire, Ulf, MD, PhD and Panayiotou, Andrie G., PhD and Tremoli, Elena, PhD and Baldassarre, Damiano, PhD and Veglia, Fabrizio, PhD and Holdt, Lesca M., MD, PhD and Beutner, Frank, MD, PhD and Gansevoort, Ron T., MD, PhD and Navis, Gerjan J., MD, PhD and Mateo Leach, Irene, PhD and Breitling, Lutz P., MD and Brenner, Hermann, MD, MPH and Thiery, Joachim, MD, MBA and Dallmeier, Dhayana, MD and Franco-Cereceda, Anders, MD, PhD and Boer, Jolanda M.A., PhD and Stephens, Jeffrey W., PhD and Hofker, Marten H., PhD and Tedgui, Alain, PhD and Hofman, Albert, MD, PhD and Uitterlinden, André G., PhD and Adamkova, Vera, MD, PhD and Pitha, Jan, MD, PhD and Onland-Moret, N. Charlotte, PhD and Cramer, Maarten J., MD, PhD and Nathoe, Hendrik M., MD, PhD and Spiering, Wilko, MD, PhD and Klungel, Olaf H., PharmD, PhD and Kumari, Meena, PhD and Whincup, Peter H and Morrow, David A., MD and Braund, Peter S., MSc and Hall, Alistair S., PhD and Olsson, Anders G., MD, PhD and Doevendans, Pieter A., MD, PhD and Trip, Mieke D., MD, PhD and Tobin, Martin D., PhD and Hamsten, Anders, PhD and Watkins, Hugh, PhD and Koenig, Wolfgang, MD and Nicolaides, Andrew N., PhD and Teupser, Daniel, MD, PhD and Day, Ian N.M and Carlquist, John F., PhD and Gaunt, Tom R., PhD and Ford, Ian, PhD and Sattar, Naveed and Tsimikas, Sotirios, MD and Schwartz, Gregory G., MD PhD and Lawlor, Debbie A., PhD and Morris, Richard W., PhD and Sandhu, Manjinder S., PhD and Poledne, Rudolf, PhD and Maitland-van der Zee, Anke H., PhD and Khaw, Kay-Tee, MBBChir and Keating, Brendan J., PhD and van der Harst, Pim, MD, PhD and Price, Jackie F., MD and Mehta, Shamir R., MD, MSc and Yusuf, Salim, MBBS, DPhil and Witteman, Jaqueline C.M., PhD and Franco, Oscar H., MD, PhD and Jukema, J. Wouter, MD, PhD and de Knijff, Peter, PhD and Tybjaerg-Hansen, Anne, MD, DMSc and Rader, Daniel J., MD and Farrall, Martin, MD, PhD and Samani, Nilesh J., MD and ...
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A2 (sPLA2 )-IIA in cardiovascular disease. Background Higher circulating levels... 
Cardiovascular | Internal Medicine | drug development | epidemiology | genetics | cardiovascular diseases | Mendelian randomization | Studies | Cardiovascular disease | Heart attacks | Drug therapy | Mortality | Cholesterol
Journal Article
by Sarwar, Nadeem and Butterworth, Adam S and Freitag, Daniel F and Gregson, John and Willeit, Peter and Gorman, Donal N and Gao, Pei and Saleheen, Danish and Rendon, Augusto and Nelson, Christopher P and Braund, Peter S and Hall, Alistair S and Chasman, Daniel I and Tybjærg-Hansen, Anne and Chambers, John C and Benjamin, Emelia J and Franks, Paul W and Clarke, Robert and Wilde, Arthur A. M and Trip, Mieke D and Steri, Maristella and Witteman, Jacqueline C. M and Qi, Lu and van der Schoot, C. Ellen and de Faire, Ulf and Erdmann, Jeanette and Stringham, Heather M and Koenig, Wolfgang and Rader, Daniel J and Melzer, David and Reich, David and Psaty, Bruce M and Kleber, Marcus E and Panagiotakos, Demosthenes B and Willeit, Johann and Wennberg, Patrik and Woodward, Mark and Adamovic, Svetlana and Rimm, Eric B and Meade, Tom W and Gillum, Richard F and Shaffer, Jonathan A and Hofman, Albert and Onat, Altan and Kastelein, John J. P and Motazacker, Mahdi and de Jong, Jonas S. S. G and Dekker, Lucas R. C and Tanck, Michael and Bezzina, Connie R and unav and IL6R Genetics Consortium Emerging Risk Factors Collaboration and IL6R Genetics Consortium Emerging and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Wallenberg Laboratory and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Physiology and Institute of Medicine, School of Public Health and Community Medicine and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Wallenberglaboratoriet and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 379, Issue 9822, pp. 1205 - 1213
Journal Article
by Morris, Andrew P and Voight, Benjamin F and Teslovich, Tanya M and Ferreira, Teresa and Segrè, Ayellet V and Steinthorsdottir, Valgerdur and Strawbridge, Rona J and Khan, Hassan and Grallert, Harald and Mahajan, Anubha and Prokopenko, Inga and Kang, Hyun Min and Dina, Christian and Esko, Tonu and Fraser, Ross M and Kanoni, Stavroula and Kumar, Ashish and Lagou, Vasiliki and Langenberg, Claudia and Luan, Jian'An and Lindgren, Cecilia M and Müller-Nurasyid, Martina and Pechlivanis, Sonali and Rayner, N. William and Scott, Laura J and Wiltshire, Steven and Yengo, Loic and Kinnunen, Leena and Rossin, Elizabeth J and Raychaudhuri, Soumya and Johnson, Andrew D and Dimas, Antigone S and Loos, Ruth J.F and Vedantam, Sailaja and Chen, Han and Florez, Jose C and Fox, Caroline and Liu, Ching-Ti and Rybin, Denis and Couper, David J and Kao, Wen Hong L and Li, Man and Cornelis, Marilyn C and Kraft, Peter and Sun, Qi and Van Dam, Rob M and Stringham, Heather M and Chines, Peter S and Fischer, Krista and Fontanillas, Pierre and Holmen, Oddgeir L and Hunt, Sarah E and Jackson, Anne U and Kong, Augustine and Lawrence, Robert and Meyer, Julia and Perry, John R.B and Platou, Carl G.P and Potter, Simon and Rehnberg, Emil and Robertson, Neil and Sivapalaratnam, Suthesh and Stančáková, Alena and Stirrups, Kathleen and Thorleifsson, Gudmar and Tikkanen, Emmi and Wood, Andrew R and Almgren, Peter and Atalay, Mustafa and Benediktsson, Rafn and Bonnycastle, Lori L and Burtt, Noël and Carey, Jason and Charpentier, Guillaume and Crenshaw, Andrew T and Doney, Alex S.F and Dorkhan, Mozhgan and Edkins, Sarah and Emilsson, Valur and Eury, Elodie and Forsen, Tom and Gertow, Karl and Gigante, Bruna and Grant, George B and Groves, Christopher J and Guiducci, Candace and Herder, Christian and Hreidarsson, Astradur B and Hui, Jennie and James, Alan and Jonsson, Anna and Rathmann, Wolfgang and Klopp, Norman and Kravic, Jasmina and Krjutškov, Kaarel and Langford, Cordelia and Leander, Karin and Lindholm, Eero and Lobbens, Stéphane and MäNnistö, Satu and ... and unav and Meta-Anal Glucose Insulin-Related and Genetic Invest ANthropometric and Wellcome Trust Case Control and Asian Genetic Epidemiology and S Asian Type 2 Diabet SAT2D and DIAbet Genetics Replication and the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nature genetics, ISSN 1061-4036, 2012, Volume 44, Issue 9, pp. 981 - 990
To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the... 
INDIVIDUALS | MC4R | COMMON VARIANTS | METAANALYSIS | REPLICATION | GLUCOSE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | RISK | EXPRESSION | GENOME-WIDE ASSOCIATION | Type 2 diabetes | Physiological aspects | Development and progression | Genetic aspects
Journal Article