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1. Full Text Breast cancer-secreted miR-939 downregulates VE-cadherin and destroys the barrier function of endothelial monolayers
by Di Modica, Martina|Regondi, Viola|Sandri, Marco|Iorio, Marilena V.|Zanetti, Adriana|Tagliabue, Elda|Casalini, Patrizia|Triulzi, Tiziana
Cancer Letters, ISSN 0304-3835, 2016, Volume 384, pp. 94 - 100
Abstract Exosomes-secreted microRNAs play an important role in metastatic spread. During this process breast cancer cells acquire the ability to transmigrate... 
Hematology, Oncology and Palliative Medicine | Breast cancer | Metastasis | miR-939 | Exosomes | Triple-negative breast cancer | CELLS | DIAGNOSIS | ANGIOGENESIS | RISK | MICRORNAS | BIOMARKERS | VESSELS | ONCOLOGY | JUNCTIONS | DISTANT METASTASIS | Exosomes - metabolism | Cadherins - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Neoplasm Metastasis | Transfection | Time Factors | Transendothelial and Transepithelial Migration | Triple Negative Breast Neoplasms - pathology | Female | Cadherins - genetics | Paracrine Communication | Signal Transduction | Down-Regulation | Proportional Hazards Models | Permeability | Disease-Free Survival | Triple Negative Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - metabolism | Cell Line, Tumor | Human Umbilical Vein Endothelial Cells - pathology | MicroRNAs - genetics | Analysis | Molecular biology | Monomolecular films | Endothelium | Proteins | Cloning | Medical prognosis | Mortality | Conflicts of interest | Binding sites | Methods | Tumors | Index Medicus
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2. Full Text FOXP3 Expression and Overall Survival in Breast Cancer
by Andrea Merlo and Patrizia Casalini and Maria Luisa Carcangiu and Chiara Malventano and Tiziana Triulzi and Sylvie Mènard and Elda Tagliabue and Andrea Balsari
Journal of Clinical Oncology, ISSN 0732-183X, 04/2009, Volume 27, Issue 11, pp. 1746 - 1752
Purpose The transcription factor forkhead box P3 (FOXP3) up-or downregulates a large number of genes and has been recently reported to be expressed in tumor... 
RELAPSE | METASTASIS | ONCOLOGY | LYMPH-NODES | REGULATORY T-CELLS | PANCREAS | PERIPHERAL-BLOOD | RADIOTHERAPY | PREVALENCE | SUPPRESSION | TUMOR MICROENVIRONMENT | Breast Neoplasms - surgery | Forkhead Transcription Factors - biosynthesis | Prognosis | Breast Neoplasms - pathology | Humans | Middle Aged | Survival Analysis | Breast Neoplasms - mortality | Female | Breast Neoplasms - metabolism | Index Medicus
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3. Full Text Radiation Effects on Development of HER2-Positive Breast Carcinomas
by Fabio Castiglioni and Monica Terenziani and Maria Luisa Carcangiu and Raffaella Miliano and Piera Aiello and Lorenzo Bertola and Tiziana Triulzi and Patrizia Gasparini and Tiziana Camerini and Gabriella Sozzi and Franca Fossati-Bellani and Sylvie Ménard and Elda Tagliabue
Clinical Cancer Research, ISSN 1078-0432, 01/2007, Volume 13, Issue 1, pp. 46 - 51
Purpose: Neither hormone-related nor genetics risk factors have been associated with the development of highly proliferative HER2-positive breast carcinomas.... 
risk factors | cancer stem cells | HER2 | breast carcinoma | radiation | IRRADIATION | CANCER RISK | STEM-CELLS | PROFILES | HODGKINS-DISEASE | ONCOLOGY | YOUNG-WOMEN | EXPRESSION | ESTROGEN-RECEPTOR | 2ND CANCERS | MAMMARY EPITHELIAL-CELLS | Breast - radiation effects | Immunohistochemistry | Breast Neoplasms - secondary | Hodgkin Disease - pathology | Humans | Middle Aged | Risk Factors | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | Breast Neoplasms - drug therapy | Disease Progression | Hodgkin Disease - radiotherapy | Breast Neoplasms - radiotherapy | Adolescent | Aged, 80 and over | Cell Line, Tumor | Adult | Female | Neoplasms - radiotherapy | Aged | Neoplasms - pathology | Breast - pathology | Child | Index Medicus
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4. Full Text Extracellular matrix proteins as diagnostic markers of breast carcinoma
by Giussani, Marta and Landoni, Elena and Merlino, Giuseppe and Turdo, Federica and Veneroni, Silvia and Paolini, Biagio and Cappelletti, Vera and Miceli, Rosalba and Orlandi, Rosaria and Triulzi, Tiziana and Tagliabue, Elda
Journal of Cellular Physiology, ISSN 0021-9541, 08/2018, Volume 233, Issue 8, pp. 6280 - 6290
We tested the hypothesis that abnormal production of extracellular matrix (ECM) components leads to blood‐released ECM molecules representing tumor circulating... 
breast cancer | diagnosis | biomarker | tumor‐microenvironment | extracellular matrix | tumor-microenvironment | PHYSIOLOGY | COLLAGEN | PROTEOME | BONE-MARROW | SERUM | CELL BIOLOGY | STROMAL CELLS | CANCER PROGRESSION | EXPRESSION | TUMOR MICROENVIRONMENT | Carcinoma | Analysis | Collagen | Genes | Breast cancer | Diagnosis | Gene expression | Cancer | Collagens | Blood plasma | Proteins | Lysates | Breast carcinoma | Fibroblasts | Extracellular matrix | Bioindicators | Conditioning | Matrix protein | Enzyme-linked immunosorbent assay | Benign | Stroma | Patients | Nodules | Blood circulation | Cell lines | Breast | Biomarkers | Skin | Diagnostic systems | Tumors
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5. Full Text Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit
by Triulzi, Tiziana and Regondi, Viola and De Cecco, Loris and Cappelletti, Maria Rosa and Di Modica, Martina and Paolini, Biagio and Lollini, Pier Luigi and Di Cosimo, Serena and Sfondrini, Lucia and Generali, Daniele and Tagliabue, Elda
British Journal of Cancer, ISSN 0007-0920, 12/2018, Volume 119, Issue 12, pp. 1487 - 1494
BACKGROUND: Optimising the selection of HER2-targeted regimens by identifying subsets of HER2-positive breast cancer ( BC) patients who need more or less... 
PREOPERATIVE TRASTUZUMAB | THERAPY | EFFICACY | ONCOLOGY | PATHOLOGICAL RESPONSE | RESISTANCE | SUBSETS | INNATE | CELL | HER2-POSITIVE BREAST-CANCER | Animal models | Immunomodulation | Breast cancer | Gene expression | Macrophages | Patients | ErbB-2 protein | Chemotherapy | Major histocompatibility complex | Pathways | Mice | Trastuzumab | Tumors | Cancer
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6. Full Text The loss of macular ganglion cells begins from the early stages of disease and correlates with brain atrophy in multiple sclerosis patients
by Pietroboni, Anna M and Dell’Arti, Laura and Caprioli, Michela and Scarioni, Marta and Carandini, Tiziana and Arighi, Andrea and Ghezzi, Laura and Fumagalli, Giorgio G and De Riz, Milena A and Basilico, Paola and Colombi, Annalisa and Benatti, Eleonora and Triulzi, Fabio and Scarpini, Elio and Viola, Francesco and Galimberti, Daniela
Multiple Sclerosis Journal, ISSN 1352-4585, 1/2019, Volume 25, Issue 1, pp. 31 - 38
Background: The importance of neurodegeneration in multiple sclerosis (MS) is increasingly well recognized. Objectives: To evaluate retinal pathology using... 
atrophy | functional MRI | Multiple sclerosis | MRI | axonal loss | outcome measurement | OPTICAL COHERENCE TOMOGRAPHY | VISUAL PATHWAY | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | INFLAMMATION | CORTICAL ATROPHY | DYSFUNCTION | LAYER THICKNESS | Neuroimaging | Cortex (occipital) | Retina | Substantia grisea | Atrophy | Retinal ganglion cells | Magnetic resonance imaging | Thinning | Neurodegeneration | Cortex (parietal) | Morphometry | Ganglion cells | Cortex (temporal)
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7. Full Text Modulation of Pulmonary Microbiota by Antibiotic or Probiotic Aerosol Therapy: A Strategy to Promote Immunosurveillance against Lung Metastases
by Le Noci, Valentino and Guglielmetti, Simone and Arioli, Stefania and Camisaschi, Chiara and Bianchi, Francesca and Sommariva, Michele and Storti, Chiara and Triulzi, Tiziana and Castelli, Chiara and Balsari, Andrea and Tagliabue, Elda and Sfondrini, Lucia
Cell Reports, ISSN 2211-1247, 09/2018, Volume 24, Issue 13, pp. 3528 - 3538
Pulmonary immunological tolerance to inhaled particulates might create a permissive milieu for lung metastasis. Lung microbiota contribute to pulmonary... 
mouse models | lung microbiota | immunosuppression and/or suppressor cells | aerosolization | cancer immunosurveillance | antibiotics | probiotics | BREAST-CANCER | DENDRITIC CELLS | INFLAMMATION | TOLERANCE | ALVEOLAR MACROPHAGES | RISK | TUMOR-CELLS | LACTOBACILLI | T-CELLS | CELL BIOLOGY
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8. Full Text Neoplastic and Stromal Cells Contribute to an Extracellular Matrix Gene Expression Profile Defining a Breast Cancer Subtype Likely to Progress
by Triulzi, Tiziana and Casalini, Patrizia and Sandri, Marco and Ratti, Manuela and Carcangiu, Maria L and Colombo, Mario P and Balsari, Andrea and Ménard, Sylvie and Orlandi, Rosaria and Tagliabue, Elda
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e56761 - e56761
We recently showed that differential expression of extracellular matrix (ECM) genes delineates four subgroups of breast carcinomas (ECM1, -2, -3- and -4) with... 
MIGRATION | GROWTH-FACTOR-BETA | INVASION | SPARC | MICROENVIRONMENT | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | TUMOR | SIGNATURE | MICROARRAY DATA | FIBROBLASTS | Prognosis | Stromal Cells - pathology | Extracellular Matrix Proteins - genetics | Humans | Middle Aged | Stromal Cells - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Tumor Burden | Disease Progression | Breast Neoplasms - genetics | Neoplasm Grading | Breast Neoplasms - pathology | Cell Line, Tumor | Breast Neoplasms - mortality | Female | Aged | Extracellular Matrix Proteins - metabolism | Cluster Analysis | Antimitotic agents | Algorithms | Analysis | Genes | Development and progression | Breast cancer | Genetic aspects | Hormones, Sex | Antineoplastic agents | Transforming growth factors | Gene expression | Cancer | Enrichment | Slopes | Mesenchyme | Estrogen receptors | Oncology | Metastasis | Multivariate analysis | Estradiol | Subgroups | Cell adhesion & migration | Metastases | Proteins | Breast carcinoma | Quality | Fibroblasts | Extracellular matrix | Growth factors | Enzymes | Cell survival | Invasiveness | Cloning | Tumor cell lines | Clustering | Survival | Medicine | Sex hormones | Stromal cells | Collagen | Data sets | Cell lines | Breast | Tumors | Index Medicus
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9. Full Text CSF β-amyloid predicts prognosis in patients with multiple sclerosis
by Pietroboni, Anna M and Caprioli, Michela and Carandini, Tiziana and Scarioni, Marta and Ghezzi, Laura and Arighi, Andrea and Cioffi, Sara and Cinnante, Claudia and Fenoglio, Chiara and Oldoni, Emanuela and De Riz, Milena A and Basilico, Paola and Fumagalli, Giorgio G and Colombi, Annalisa and Giulietti, Giovanni and Serra, Laura and Triulzi, Fabio and Bozzali, Marco and Scarpini, Elio and Galimberti, Daniela
Multiple Sclerosis Journal, ISSN 1352-4585, 8/2019, Volume 25, Issue 9, pp. 1223 - 1231
Background: The importance of predicting disease progression in multiple sclerosis (MS) has increasingly been recognized, and hence reliable biomarkers are... 
Biomarkers | MRI | multiple sclerosis | BIOMARKER | CEREBROSPINAL-FLUID | NEUROSCIENCES | CLINICAL NEUROLOGY | VOXEL-BASED MORPHOMETRY | METABOLISM | DISABILITY | BACE1 ACTIVITY | ASSOCIATION | EXPRESSION | MS PATIENTS | Neuroimaging | Multiple sclerosis | Nuclear magnetic resonance--NMR | Prognosis | Multiple regression analysis | Cerebrospinal fluid | Substantia alba | Substantia grisea | Magnetic resonance imaging | Tau protein | β-Amyloid | Alzheimer's disease | Index Medicus
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10. Full Text MicroRNA-205 regulates HER3 in human breast cancer
by Iorio, Marilena V and Casalini, Patrizia and Piovan, Claudia and Leva, Gianpiero Di and Merlo, Andrea and Triulzi, Tiziana and Ménard, Sylvie and Croce, Carlo M and Tagliabue, Elda
Cancer Research, ISSN 0008-5472, 03/2009, Volume 69, Issue 6, pp. 2195 - 2200
An increasing amount of experimental evidence shows that microRNAs can have a causal role in breast cancer tumorigenesis as a novel class of oncogenes or tumor... 
THERAPY | SIGNATURES | ERBB3 | ONCOLOGY | CARCINOMAS | EXPRESSION | FAMILY | Genetic Therapy | Humans | Receptor, ErbB-3 - antagonists & inhibitors | Combined Modality Therapy | Phosphatidylinositol 3-Kinases - metabolism | Receptor, ErbB-3 - genetics | Breast Neoplasms - drug therapy | Breast Neoplasms - therapy | Breast Neoplasms - genetics | Transfection | Breast Neoplasms - pathology | Cell Line, Tumor | MicroRNAs - genetics | Cell Growth Processes - genetics | Oncogene Protein v-akt - metabolism | Quinazolines - pharmacology | Genes, Tumor Suppressor | Index Medicus
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11. Full Text Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases
by Le Noci, V and Sommariva, M and Bianchi, F and Triulz, T and Tagliabue, E and Balsari, A and Sfondrini, L
JOURNAL OF IMMUNOLOGY RESEARCH, ISSN 2314-8861, 2019, Volume 2019, pp. 1 - 8
Caloric restriction mimetics (CRMs), compounds that mimic the biochemical effects of nutrient deprivation, administered via systemic route promote antitumor... 
TUMOR-CELLS | PROLIFERATION | AEROSOL | AUTOPHAGY | IMMUNOLOGY | Lipoic acid | Toxicity | Lung | Genes | Lymphocytes T | Metastasis | Macrophages | Autophagy | Anticancer properties | Metastases | Dietary restrictions | Cell activation | CD103 antigen | Lymphocytes | Spermidine | Natural killer cells | Stat1 protein | Alveoli | Adenosine triphosphate | Deprivation | Phenotypes | Dendritic cells | Melanoma | Weight loss | Implantation | Interleukin 12 | Immunosurveillance | CD3 antigen | Metabolism | Acids | Lungs | Interleukin 10 | Aerosols | Antitumor activity | Mice | Phagocytosis | Tumors | Cancer
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12. Full Text Abstract 748: Targeting the crosstalk between tumor cells and adipocytes to block breast cancer progression
by Triulzi, Tiziana and Ciravolo, Valentina and Regondi, Viola and Di Modica, Martina and Chiodoni, Claudia and Tagliabue, Elda
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 748 - 748
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13. Full Text Monozygotic Twins with Frontotemporal Dementia Due to Thr272fs GRN Mutation Discordant for Age at Onset
by Fumagalli, Giorgio Giulio and Sacchi, Luca and Basilico, Paola and Arighi, Andrea and Carandini, Tiziana and Scarioni, Marta and Colombi, Annalisa and Pietroboni, Anna and Ghezzi, Laura and Fenoglio, Chiara and Serpente, Maria and D'Anca, Marianna and Arcaro, Marina and Mercurio, Matteo and Triulzi, Fabio and Scola, Elisa and Marotta, Giorgio and Scarpini, Elio and Galimberti, Daniela
Journal of Alzheimer's Disease, ISSN 1387-2877, 2019, Volume 67, Issue 4, pp. 1173 - 1179
We report the case of two monozygotic twins with Thr272fs mutation in progranulin gene. Both patients developed frontotemporal dementia with 5 years difference... 
atrophy | Age at onset | twins | frontotemporal dementia | progranulin (GRN) | cerebrospinal fluid | PROGRANULIN MUTATIONS | ENVIRONMENTAL RISK-FACTORS | BEHAVIORAL VARIANT | NEUROSCIENCES | Neuroimaging | Phenotypes | Executive function | Medical imaging | Psychology | Environmental factors | Cerebrospinal fluid | Measuring techniques | Atrophy | Neurology | Magnetic resonance imaging | Tau protein | Dementia disorders | Mutation | Frontotemporal dementia | Twins | Smoking | Dementia
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14. Full Text Word and Picture Version of the Free and Cued Selective Reminding Test (FCSRT): Is There Any Difference?
by Arighi, Andrea and Carandini, Tiziana and Mercurio, Matteo and Carpani, Giovanni and Pietroboni, Anna Margherita and Fumagalli, Giorgio and Ghezzi, Laura and Basilico, Paola and Calvi, Alberto and Scarioni, Marta and De Riz, Milena and Fenoglio, Chiara and Scola, Elisa and Triulzi, Fabio and Galimberti, Daniela and Scarpini, Elio
Journal of Alzheimer's Disease, ISSN 1387-2877, 2018, Volume 61, Issue 1, pp. 47 - 52
The Free and Cued Selective Reminding Test (FCSRT) is the most commonly used neuropsychological test to evaluate episodic memory. Two variants of FCSRT exist,... 
Atrophy | neuropsychology | dementia | magnetic resonance imaging | memory | NEUROSCIENCES | Pictures | Brain | Correlation analysis | Magnetic resonance | Memory | Cognitive ability | Information processing | Visual stimuli | Patients | Hippocampus | Index Medicus
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15. Full Text Maspin influences response to doxorubicin by changing the tumor microenvironment organization
by Triulzi, Tiziana and Ratti, Manuela and Tortoreto, Monica and Ghirelli, Cristina and Aiello, Piera and Regondi, Viola and Di Modica, Martina and Cominetti, Denis and Carcangiu, Maria L and Moliterni, Angela and Balsari, Andrea and Casalini, Patrizia and Tagliabue, Elda
International Journal of Cancer, ISSN 0020-7136, 06/2014, Volume 134, Issue 12, pp. 2789 - 2797
Altered degradation and deposition of extracellular matrix are hallmarks of tumor progression and response to therapy. From a microarray supervised analysis on... 
maspin | drug delivery | response to doxorubicin | extracellular matrix | CELLS | SOLID TUMORS | DRUG-RESISTANCE | CHEMOTHERAPY | BREAST-CANCER | ONCOLOGY | GROWTH | EXTRACELLULAR-MATRIX | EXPRESSION | CARCINOMA | MAMMARY | Tumor Microenvironment - drug effects | Doxorubicin - therapeutic use | Serpins - metabolism | Humans | Extracellular Matrix - metabolism | Drug Resistance, Neoplasm | Breast Neoplasms - drug therapy | Disease Progression | Breast Neoplasms - metabolism | Serpins - immunology | Collagen - metabolism | Extracellular Matrix - genetics | Serpins - biosynthesis | Animals | Antibiotics, Antineoplastic - therapeutic use | MCF-7 Cells | Mice, Nude | Cell Line, Tumor | Female | Cell Proliferation - drug effects | Mice | Ovarian Neoplasms - metabolism | Ovarian Neoplasms - drug therapy | Antibodies, Monoclonal - immunology | Drugs | Drug delivery systems | Anthracyclines | Development and progression | Ovarian cancer | Vehicles | Chemotherapy | Protease inhibitors | Proteases | Collagen | Analysis | Monoclonal antibodies | Cancer | Breast cancer | Drug resistance | Tumors | Index Medicus
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16. Predictive biomarkers in the treatment of HER2-positive breast cancer: an ongoing challenge
by Triulzi, Tiziana and Bianchi, Giulia Valeria and Tagliabue, Elda
Future oncology (London, England), 06/2016, Volume 12, Issue 11, p. 1413
The transmembrane tyrosine kinase receptor HER2 is overexpressed in 20% of invasive breast cancers and is associated with more aggressive disease. Until the... 
Biomarkers, Tumor - analysis | Humans | Drug Resistance, Neoplasm | Female | Receptor, ErbB-2 - analysis | Molecular Targeted Therapy | Breast Neoplasms - drug therapy | Precision Medicine
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17. Full Text Abstract 5207: miR-491 and miR-218: Two possible tools to reduce FOXP3 expression in breast carcinomas
by Modica, Martina D and Triulzi, Tiziana and Regondi, Viola and Iorio, Marilena V and Balsari, Andrea and Tagliabue, Elda and Casalini, Patrizia
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 5207 - 5207
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18. Full Text Stromal responses among carcinomas-letter
by Triulzi, Tiziana and Orlandi, Rosaria and Tagliabu, Elda
Clinical Cancer Research, ISSN 1078-0432, 2014, Volume 20, Issue 5, pp. 1396 - 1396
BREAST-CANCER | ONCOLOGY | CHEMOTHERAPY | Prostatic Neoplasms - pathology | Breast Neoplasms - pathology | Stromal Cells - pathology | Colonic Neoplasms - pathology | Humans | Ovarian Neoplasms - pathology | Female | Male | Gene Expression Profiling | Fibroblasts - pathology | Index Medicus
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