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Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 70, Issue 5, pp. 558 - 568
High-sensitivity assays can quantify cardiac troponins I and T (hs-cTnI, hs-cTnT) in individuals with no clinically manifest myocardial injury. The goal of... 
primary prevention | cardiovascular disease | coronary heart disease | biomarker | systematic review | stroke | C-REACTIVE PROTEIN | MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | ASSAY | I LEVELS | NATRIURETIC PEPTIDE | FAILURE | ATHEROSCLEROSIS RISK | GENERAL-POPULATION | CORONARY-HEART-DISEASE | ASSOCIATION | Risk Assessment - methods | Global Health | Humans | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Troponin - blood | Biomarkers - blood | Cardiovascular Diseases - diagnosis | Incidence | Medical research | Medical colleges | Medicine, Experimental | Research institutes | Cardiology | Epidemiology | Public health | Stroke (Disease) | Prevention | Risk factors | Heart attack | Heart | Cardiovascular disease | Pravastatin | Calcium-binding protein | Older people | Atherosclerosis | Heart diseases | Age | Heart failure | Hypertension | Stroke | Health risks | Risk analysis | Coronary artery disease | Cholesterol | Meta-analysis | Studies | Sensitivity | Troponin | Coronary vessels | Biomarkers | Cardiovascular diseases | Health risk assessment | Geriatrics | HDL-C, high-density lipoprotein cholesterol | eGFR, estimated glomerular filtration rate | CI, confidence interval | CVD, cardiovascular disease | HR, hazard ratio | MI, myocardial infarction | hs-cTnT, high-sensitivity cardiac troponin T | RR, relative risk | CHD, coronary heart disease | CRP, C-reactive protein | hs-cTnI, high-sensitivity cardiac troponin I | Original Investigation | NT-proBNP, N-terminal pro–B-type natriuretic peptide | NRI, net reclassification index
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2014, Volume 63, Issue 12, pp. 1200 - 1210
Journal Article
by Nikpay, Majid and Goel, Anuj and Won, Hong-Hee and Hall, Leanne M and Willenborg, Christina and Kanoni, Stavroula and Saleheen, Danish and Kyriakou, Theodosios and Nelson, Christopher P and CHopewell, Jemma and Webb, Thomas R and Zeng, Lingyao and Dehghan, Abbas and Alver, Maris and MArmasu, Sebastian and Auro, Kirsi and Bjonnes, Andrew and Chasman, Daniel I and Chen, Shufeng and Ford, Ian and Franceschini, Nora and Gieger, Christian and Grace, Christopher and Gustafsson, Stefan and Huang, Jie and Hwang, Shih-Jen and Kim, Yun Kyoung and Kleber, Marcus E and Lau, King Wai and Lu, Xiangfeng and Lu, Yingchang and Lyytikäinen, Leo-Pekka and Mihailov, Evelin and Morrison, Alanna C and Pervjakova, Natalia and Qu, Liming and Rose, Lynda M and Salfati, Elias and Saxena, Richa and Scholz, Markus and Smith, Albert V and Tikkanen, Emmi and Uitterlinden, Andre and Yang, Xueli and Zhang, Weihua and Zhao, Wei and De Andrade, Mariza and De Vries, Paul S and Van Zuydam, Natalie R and Anand, Sonia S and Bertram, Lars and Beutner, Frank and Dedoussis, George and Frossard, Philippe and Gauguier, Dominique and Goodall, Alison H and Gottesman, Omri and Haber, Marc and Han, Bok-Ghee and Huang, Jianfeng and Jalilzadeh, Shapour and Kessler, Thorsten and König, Inke R and Lannfelt, Lars and Lieb, Wolfgang and Lind, Lars and MLindgren, Cecilia and Lokki, Marja-Liisa and Magnusson, Patrik K and Mallick, Nadeem H and Mehra, Narinder and Meitinger, Thomas and Memon, Fazal-Uur-Rehman and Morris, Andrew P and Nieminen, Markku S and Pedersen, Nancy L and Peters, Annette and Rallidis, Loukianos S and Rasheed, Asif and Samuel, Maria and Shah, Svati H and Sinisalo, Juha and EStirrups, Kathleen and Trompet, Stella and Wang, Laiyuan and Zaman, Khan S and Ardissino, Diego and Boerwinkle, Eric and Borecki, Ingrid B and Bottinger, Erwin P and Buring, Julie E and Chambers, John C and Collins, Rory and Cupples, Ladrienne and Danesh, John and Demuth, Ilja and Elosua, Roberto and Epstein, Stephen E and Esko, Tõnu and Feitosa, Mary F and ... and the CARDIoGRAMplusC4D Consortium and CARDIoGRAMplusC4D Consortium
Nature genetics, ISSN 1546-1718, 2015, Volume 47, Issue 10, pp. 1121 - 1130
Journal Article
by Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R and Torres, Jason M and Rayner, N. William and Payne, Anthony J and Steinthorsdottir, Valgerdur and Scott, Robert A and Grarup, Niels and Cook, James P and Schmidt, Ellen M and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael H and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F and Below, Jennifer E and Bowden, Donald W and Chambers, John Campbell and Kim, Young Jin and Ng, Maggie C. Y and Petty, Lauren E and Sim, Xueling and Zhang, Weihua and Bennett, Amanda J and Bork-Jensen, Jette and Brummett, Chad M and Canouil, Mickaël and Ec kardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon L. R and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E and Luan, Jian’an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C and Ford, Ian and Franco, Oscar H and Frayling, Timothy M and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T and Herder, Christian and Ikram, M. Arfan and Ingelsson, Martin and Jørgensen, Marit E and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L and Morris, Andrew D and Nadkarni, Girish and Pankow, James S and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R and Dupuis, Josée and Peyser, Patricia A and Zeggini, Eleftheria and Loos, Ruth J. F and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S and Jukema, J. Wouter and Palmer, Colin N. A and Grallert, Harald and Metspalu, Andres and ...
Nature genetics, ISSN 1546-1718, 2018, Volume 50, Issue 11, pp. 1505 - 1513
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 387, pp. S37 - S37
Abstract Background We have recently shown that the C-reactive protein (CRP) response to statin therapy is highly variable, with 45% of people on atorvastatin... 
Internal Medicine | Genetic research | C-reactive protein | Single nucleotide polymorphisms | Genomics | Statins
Journal Article
by Christophersen, Ingrid E and Rienstra, Michiel and Roselli, Carolina and Yin, Xiaoyan and Geelhoed, Bastiaan and Barnard, John and Lin, Honghuang and Arking, Dan E and Smith, Albert V and Albert, Christine M and Chaffin, Mark and Tucker, Nathan R and Li, Molong and Klarin, Derek and Bihlmeyer, Nathan A and Low, Siew-Kee and Weeke, Peter E and Müller-Nurasyid, Martina and Smith, J Gustav and Brody, Jennifer A and Niemeijer, Maartje N and Dörr, Marcus and Trompet, Stella and Huffman, Jennifer and Gustafsson, Stefan and Schurmann, Claudia and Kleber, Marcus E and Lyytikäinen, Leo-Pekka and Seppälä, Ilkka and Malik, Rainer and Horimoto, Andrea R V R and Perez, Marco and Sinisalo, Juha and Aeschbacher, Stefanie and Thériault, Sébastien and Yao, Jie and Radmanesh, Farid and Weiss, Stefan and Teumer, Alexander and Choi, Seung Hoan and Weng, Lu-Chen and Clauss, Sebastian and Deo, Rajat and Rader, Daniel J and Shah, Svati H and Sun, Albert and Hopewell, Jemma C and Debette, Stephanie and Chauhan, Ganesh and Yang, Qiong and Worrall, Bradford B and Paré, Guillaume and Kamatani, Yoichiro and Hagemeijer, Yanick P and Verweij, Niek and Siland, Joylene E and Kubo, Michiaki and Smith, Jonathan D and Van Wagoner, David R and Bis, Joshua C and Perz, Siegfried and Psaty, Bruce M and Ridker, Paul M and Magnani, Jared W and Harris, Tamara B and Launer, Lenore J and Shoemaker, M Benjamin and Padmanabhan, Sandosh and Haessler, Jeffrey and Bartz, Traci M and Waldenberger, Melanie and Lichtner, Peter and Arendt, Marina and Krieger, Jose E and Kähönen, Mika and Risch, Lorenz and Mansur, Alfredo J and Peters, Annette and Smith, Blair H and Lind, Lars and Scott, Stuart A and Lu, Yingchang and Bottinger, Erwin B and Hernesniemi, Jussi and Lindgren, Cecilia M and Wong, Jorge A and Huang, Jie and Eskola, Markku and Morris, Andrew P and Ford, Ian and Reiner, Alex P and Delgado, Graciela and Chen, Lin Y and Chen, Yii-Der Ida and Sandhu, Roopinder K and Li, Man and Boerwinkle, Eric and Eisele, Lewin and Lannfelt, Lars and Rost, Natalia and ... and METASTROKE Consortium of the ISGC and the AFGen Consortium and Neurology Working Group of the CHARGE Consortium and Neurology Working Grp CHARGE and AFGen Consortium and METASTROKE Consortium ISGC and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Geriatrik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature genetics, ISSN 1546-1718, 2017, Volume 49, Issue 6, pp. 946 - 952
Journal Article
Journal Article
by Jiang, Xia and O’Reilly, Paul F and Aschard, Hugues and Hsu, Yi-Hsiang and Richards, J. Brent and Dupuis, Josée and Ingelsson, Erik and Karasik, David and Pilz, Stefan and Berry, Diane and Kestenbaum, Bryan and Zheng, Jusheng and Luan, Jianan and Sofianopoulou, Eleni and Streeten, Elizabeth A and Albanes, Demetrius and Lutsey, Pamela L and Yao, Lu and Tang, Weihong and Econs, Michael J and Wallaschofski, Henri and Völzke, Henry and Zhou, Ang and Power, Chris and McCarthy, Mark I and Michos, Erin D and Boerwinkle, Eric and Weinstein, Stephanie J and Freedman, Neal D and Huang, Wen-Yi and Van Schoor, Natasja M and van der Velde, Nathalie and Groot, Lisette C. P. G. M. de and Enneman, Anke and Cupples, L. Adrienne and Booth, Sarah L and Vasan, Ramachandran S and Liu, Ching-Ti and Zhou, Yanhua and Ripatti, Samuli and Ohlsson, Claes and Vandenput, Liesbeth and Lorentzon, Mattias and Eriksson, Johan G and Shea, M. Kyla and Houston, Denise K and Kritchevsky, Stephen B and Liu, Yongmei and Lohman, Kurt K and Ferrucci, Luigi and Peacock, Munro and Gieger, Christian and Beekman, Marian and Slagboom, Eline and Deelen, Joris and Heemst, Diana van and Kleber, Marcus E and März, Winfried and de Boer, Ian H and Wood, Alexis C and Rotter, Jerome I and Rich, Stephen S and Robinson-Cohen, Cassianne and den Heijer, Martin and Jarvelin, Marjo-Riitta and Cavadino, Alana and Joshi, Peter K and Wilson, James F and Hayward, Caroline and Lind, Lars and Michaëlsson, Karl and Trompet, Stella and Zillikens, M. Carola and Uitterlinden, Andre G and Rivadeneira, Fernando and Broer, Linda and Zgaga, Lina and Campbell, Harry and Theodoratou, Evropi and Farrington, Susan M and Timofeeva, Maria and Dunlop, Malcolm G and Valdes, Ana M and Tikkanen, Emmi and Lehtimäki, Terho and Lyytikäinen, Leo-Pekka and Kähönen, Mika and Raitakari, Olli T and Mikkilä, Vera and Ikram, M. Arfan and Sattar, Naveed and Jukema, J. Wouter and Wareham, Nicholas J and Langenberg, Claudia and Forouhi, Nita G and Gundersen, Thomas E and Khaw, Kay-Tee and Butterworth, Adam S and Danesh, John and Spector, Timothy and ... and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1 - 12
Journal Article
Journal Article