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by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2010, Volume 107, Issue 38, pp. 16691 - 16696
Mutations in PARK2/Parkin, which encodes a ubiquitin E3 ligase, cause autosomal recessive Parkinson disease (PD). Here we show that the nonreceptor tyrosine... 
Phosphorylation | Protective effects | Neurons | Cell death | Ubiquitins | Substantia nigra | Antibodies | Parkinson disease | Immunoblotting | Physiological regulation | Ubiquitin | AIMP2 | STI-571 | ACTIVATION | LIGASE ACTIVITY | MULTIDISCIPLINARY SCIENCES | FAMILY KINASES | ubiquitin | S-NITROSYLATION | SUBSTRATE | DISEASE | MICE | CELL | GENE-PRODUCT | AGGREGATION | Humans | Stress, Physiological | Molecular Sequence Data | Ubiquitin-Protein Ligases - antagonists & inhibitors | Neurons - cytology | PC12 Cells | Recombinant Fusion Proteins - metabolism | Brain - metabolism | Ubiquitination | Cell Death | Neurons - metabolism | Parkinson Disease - metabolism | Dopamine - metabolism | Amino Acid Sequence | Cell Line | Parkinson Disease - pathology | Ubiquitin-Protein Ligases - metabolism | Rats | Parkinson Disease - genetics | Recombinant Fusion Proteins - chemistry | Gene Knockout Techniques | Ubiquitin-Protein Ligases - chemistry | Mice, Knockout | Animals | Proto-Oncogene Proteins c-abl - metabolism | Recombinant Fusion Proteins - genetics | Mice | Mutation | In Vitro Techniques | Ubiquitin-Protein Ligases - genetics | Parkinson's disease | Protein tyrosine kinase | Development and progression | Research | Observations | Properties | Ubiquitin-proteasome system | Proteins | Neurotoxicity | Dopamine | Parkinsons disease | Kinases | Apoptosis | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2013, Volume 110, Issue 51, pp. E4968 - E4977
Journal Article
by Naj, Adam C and Jun, Gyungah and Beecham, Gary W and Wang, Li-San and Vardarajan, Badri Narayan and Buros, Jacqueline and Gallins, Paul J and Buxbaum, Joseph D and Jarvik, Gail P and Crane, Paul K and Larson, Eric B and Bird, Thomas D and Boeve, Bradley F and Graff-Radford, Neill R and De Jager, Philip L and Evans, Denis and Schneider, Julie A and Carrasquillo, Minerva M and Ertekin-Taner, Nilufer and Younkin, Steven G and Cruchaga, Carlos and Kauwe, John S. K and Nowotny, Petra and Kramer, Patricia and Hardy, John and Huentelman, Matthew J and Myers, Amanda J and Barmada, Michael M and Demirci, F Yesim and Baldwin, Clinton T and Green, Robert C and Rogaeva, Ekaterina and George-Hyslop, Peter St and Arnold, Steven E and Barber, Robert and Beach, Thomas and Bigio, Eileen H and Bowen, James D and Boxer, Adam and Burke, James R and Cairns, Nigel J and Carlson, Chris S and Carney, Regina M and Carroll, Steven L and Chui, Helena C and Clark, David G and Corneveaux, Jason and Cotman, Carl W and Cummings, Jeffrey L and Decarli, Charles and Dekosky, Steven T and Diaz-Arrastia, Ramon and Dick, Malcolm and Dickson, Dennis W and Ellis, William G and Faber, Kelley M and Fallon, Kenneth B and Farlow, Martin R and Ferris, Steven and Frosch, Matthew P and Galasko, Douglas R and Ganguli, Mary and Gearing, Marla and Geschwind, Daniel H and Ghetti, Bernardino and Gilbert, John R and Gilman, Sid and Giordani, Bruno and Glass, Jonathan D and Growdon, John H and Hamilton, Ronald L and Harrell, Lindy E and Head, Elizabeth and Honig, Lawrence S and Hulette, Christine M and Hyman, Bradley T and Jicha, Gregory A and Jin, Lee-Way and Johnson, Nancy and Karlawish, Jason and Karydas, Anna and Kaye, Jeffrey A and Kim, Ronald and Koo, Edward H and Kowall, Neil W and Lah, James J and Levey, Allan I and Lieberman, Andrew P and Lopez, Oscar L and MacK, Wendy J and Marson, Daniel C and Martiniuk, Frank and Mash, Deborah C and Masliah, Eliezer and McCormick, Wayne C and McCurry, Susan M and McDavid, Andrew N and McKee, Ann C and Mesulam, Marsel and Miller, Bruce L and ...
Nature Genetics, ISSN 1061-4036, 05/2011, Volume 43, Issue 5, pp. 436 - 443
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7491, pp. 195 - 200
Journal Article
Neuron, ISSN 0896-6273, 04/2017, Volume 94, Issue 1, pp. 93 - 107.e6
Journal Article