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1. Full Text Intracellular pattern recognition receptors in the host response
by Karin, Michael and Meylan, Etienne and Tschopp, Jürg
Nature (London), ISSN 0028-0836, 07/2006, Volume 442, Issue 7098, pp. 39 - 44
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell receptors | Miscellaneous | Molecular and cellular biology | Cell structures and functions | Immunity, Innate - immunology | Animals | Humans | Adaptor Proteins, Signal Transducing - immunology | Intracellular Signaling Peptides and Proteins - immunology | RNA, Viral - immunology | Inflammation - immunology | Proteins | Pathogens | Immunology | Biomedical research | Sensors | Microbiology | Index Medicus
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2. Full Text Mitochondria: Sovereign of inflammation?
by Tschopp, Jürg
European journal of immunology, ISSN 0014-2980, 05/2011, Volume 41, Issue 5, pp. 1196 - 1202
Innate immunity | Immune regulation | Inflammation | Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Signal Transduction | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Interleukin-1beta - immunology | Inflammation - immunology | Mitochondria - metabolism | Mitochondria - pathology | Immunity, Innate | Autophagy | Inflammation - metabolism | Animals | Carrier Proteins - metabolism | Interleukin-1beta - metabolism | Inflammasomes - immunology | Mice | Mitochondria | Immune system | Index Medicus
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3. Full Text The RIP kinases: crucial integrators of cellular stress
by Meylan, Etienne and Tschopp, Jürg
Trends in biochemical sciences (Amsterdam. Regular ed.), ISSN 0968-0004, 03/2005, Volume 30, Issue 3, pp. 151 - 159
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Signal Transduction | Protein-Serine-Threonine Kinases - physiology | Humans | Protein-Serine-Threonine Kinases - genetics | Molecular Sequence Data | NF-kappa B - metabolism | Keratinocytes - cytology | Immunity, Innate | Sequence Homology, Amino Acid | Animals | Models, Biological | Tumor Necrosis Factor-alpha - physiology | Mice | Protein-Serine-Threonine Kinases - chemistry | Apoptosis - physiology | Keratinocytes - enzymology | Cell Survival - physiology | Soil chemistry | Proteins | Index Medicus
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4. Full Text Identification of Bacterial Muramyl Dipeptide as Activator of the NALP3/Cryopyrin Inflammasome
by Martinon, Fabio and Agostini, Laetitia and Meylan, Etienne and Tschopp, Jürg
Current biology, ISSN 0960-9822, 11/2004, Volume 14, Issue 21, pp. 1929 - 1934
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Peptidoglycan - metabolism | Interleukin-1 - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Urticaria - metabolism | Cells, Cultured | Caspase 1 - metabolism | Inflammation - immunology | Acetylmuramyl-Alanyl-Isoglutamine - metabolism | Syndrome | Inflammation - metabolism | Macrophages - metabolism | Carrier Proteins - metabolism | Autoimmunity - immunology | Plasmids - genetics | Chromatography, Gel | Amyloidosis - metabolism | Index Medicus
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5. Full Text Toll-Like Receptors and RNA Helicases: Two Parallel Ways to Trigger Antiviral Responses
by Meylan, Etienne and Tschopp, Jürg
Molecular cell, ISSN 1097-2765, 2006, Volume 22, Issue 5, pp. 561 - 569
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | DEAD Box Protein 58 | RNA Helicases - metabolism | DEAD-box RNA Helicases | Signal Transduction | Humans | Cytoplasm - metabolism | Immunity, Innate | Toll-Like Receptor 3 - metabolism | Interferon-Induced Helicase, IFIH1 | Animals | Models, Biological | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | Toll-Like Receptors - metabolism | Virus Replication - physiology | RNA | Index Medicus
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6. Full Text A role for mitochondria in NLRP3 inflammasome activation
by Menu, Philippe and Zhou, Rongbin and Yazdi, Amir S and Tschopp, Jürg
Nature (London), ISSN 0028-0836, 01/2011, Volume 469, Issue 7329, pp. 221 - 225
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Inflammation | Molecular and cellular biology | Inflammation - pathology | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Endoplasmic Reticulum - metabolism | Autophagy - drug effects | Inflammation - metabolism | Macrophages - secretion | Thioredoxins - genetics | Inflammasomes - drug effects | Interleukin-1beta - metabolism | Cytoskeletal Proteins - metabolism | Thioredoxins - metabolism | Interleukin-1beta - secretion | Cell Line | Macrophages - pathology | Mice, Inbred C57BL | Mice, Transgenic | Mitochondria - metabolism | Macrophages - cytology | Mitochondria - drug effects | Mitochondria - pathology | Immunity, Innate | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | CARD Signaling Adaptor Proteins | Mice | Mice, Inbred BALB C | Voltage-Dependent Anion Channels - metabolism | Oligomers | Physiological aspects | Mitochondria | Chemical properties | Proteins | Mutation | Autophagy | Apoptosis | Index Medicus
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7. Full Text Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
by Guarda, Greta and Braun, Marion and Staehli, Francesco and Tardivel, Aubry and Mattmann, Chantal and Förster, Irmgard and Farlik, Matthias and Decker, Thomas and Du Pasquier, Renaud A and Romero, Pedro and Tschopp, Jürg
Immunity (Cambridge, Mass.), ISSN 1074-7613, 02/2011, Volume 34, Issue 2, pp. 213 - 223
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-1 - genetics | Inflammasomes - metabolism | STAT1 Transcription Factor - deficiency | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Monocytes - metabolism | Monocytes - immunology | Interleukin-10 - physiology | Interleukin-1 - biosynthesis | Interferon-beta - therapeutic use | Interferon Type I - biosynthesis | STAT3 Transcription Factor - physiology | Candida albicans - physiology | Interferon Type I - physiology | Caspase 1 - physiology | Candidiasis - immunology | Carrier Proteins - physiology | Peritonitis - etiology | STAT1 Transcription Factor - physiology | Poly I-C - pharmacology | Disease Susceptibility | Mice, Inbred C57BL | Peritonitis - immunology | STAT1 Transcription Factor - genetics | Gene Expression Regulation - drug effects | Animals | Candidiasis - etiology | Caspase 1 - genetics | Caspase 1 - deficiency | Interferon Type I - genetics | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Apoptosis Regulatory Proteins - physiology | Cells, Cultured - metabolism | Mice | Interferon Inducers - pharmacology | Multiple Sclerosis - drug therapy | Interferon | Infections | Cytokines | Viral infections | Molecular weight | Immune system | Index Medicus
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8. Full Text Thioredoxin-interacting protein links oxidative stress to inflammasome activation
by