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The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 18, pp. 1738 - 1748
Journal Article
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 1, pp. 25 - 32
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 6, pp. 791 - 800
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 7, pp. 904 - 916
Summary Background Phosphatidylinositol 3-kinase (PI3K) pathway activation is a hallmark of endocrine therapy-resistant, hormone receptor-positive breast... 
Hematology, Oncology and Palliative Medicine | HETEROGENEITY | WOMEN | PALBOCICLIB | THERAPY | EXEMESTANE | ONCOLOGY | MUTATION | RESISTANCE | COMBINATION | AROMATASE INHIBITORS | PI3K INHIBITOR | Estradiol - analogs & derivatives | Humans | Middle Aged | Aminopyridines - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Response Evaluation Criteria in Solid Tumors | Alanine Transaminase - blood | Receptors, Estrogen - analysis | Fulvestrant | Receptors, Progesterone - analysis | Breast Neoplasms - chemistry | Neoplasm Metastasis | Hyperglycemia - chemically induced | DNA, Neoplasm - blood | DNA Mutational Analysis | Exanthema - chemically induced | Postmenopause | Female | Morpholines - adverse effects | Aminopyridines - administration & dosage | Drug Eruptions - etiology | Double-Blind Method | Morpholines - administration & dosage | Estradiol - administration & dosage | Survival Rate | Signal Transduction - genetics | Breast Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Disease-Free Survival | Retreatment | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Aspartate Aminotransferases - blood | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Receptor, ErbB-2 - analysis | Antimitotic agents | Medical colleges | Clinical trials | Product development | Breast cancer | Postmenopausal women | Hormones | Antineoplastic agents | Analysis
Journal Article
The Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 09/2017, Volume 172, p. 166
Endocrine resistance remains a challenge and an unmet need for managing hormone receptor-positive breast cancer. The mechanisms of endocrine resistance are... 
Women | Studies | Endocrine system | Breast cancer
Journal Article
Journal Article
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 09/2017, Volume 172, pp. 166 - 175
Endocrine resistance remains a challenge and an unmet need for managing hormone receptor-positive breast cancer. The mechanisms of endocrine resistance are... 
Hormone receptor | Estrogen receptor | Endocrine resistance | Breast cancer | NONSTEROIDAL AROMATASE INHIBITORS | PENTOSE-PHOSPHATE PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TAMOXIFEN RESISTANCE | EVEROLIMUS PLUS EXEMESTANE | GROWTH-FACTOR RECEPTOR | RANDOMIZED PHASE-II | ESTROGEN-RECEPTOR-ALPHA | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | POSTMENOPAUSAL WOMEN | HORMONE-RECEPTOR | Receptor, Epidermal Growth Factor - genetics | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Receptor, ErbB-2 - genetics | Humans | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Benzamides - therapeutic use | Molecular Targeted Therapy - trends | Aminopyridines - therapeutic use | Everolimus - therapeutic use | Female | Receptor, ErbB-2 - antagonists & inhibitors | Molecular Targeted Therapy - methods | Morpholines - therapeutic use | Pyridines - therapeutic use | Receptors, Estrogen - genetics | Estradiol - therapeutic use | Signal Transduction | Receptors, Estrogen - antagonists & inhibitors | Piperazines - therapeutic use | Breast Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Breast Neoplasms - genetics | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mitogen-Activated Protein Kinases - genetics | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Medical colleges | Care and treatment | Hormones | Health aspects | Estrogen
Journal Article