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by Joshi, Peter and Esko, Tõnu and Mattsson, Hannele and Eklund, Niina and Gandin, Ilaria and Nutile, T and Jackson, Anne and Schurmann, Claudia and Smith, G.D and Zhang, Weihua and Okada, Yukinori and Stancáková, Alena and Faul, Jessica D and Zhao, Wei and Bartz, Traci M and Concas, M.P and Franceschini, Nora and Enroth, Stefan and Vitart, Veronique and Trompet, Stella and Guo, Xiuqing and Chasman, Daniel and O'Connel, Jeffrey R and Corre, Tanguy and Nongmaithem, Suraj S and Chen, Yuning and Mangino, Massimo and Ruggiero, D and Traglia, Michela and Farmaki, Aliki-Eleni and Kacprowski, Tim and Bjonnes, Anew and Spek, Ashley and Wu, Ying and Giri, Anil K and Yanek, Lisa and Wang, Lihua and Hofer, Edith and Rietveld, Niels and McLeod, Olga and Cornelis, Marilyn and Pattaro, Cristian and Verweij, Niek and Baumbach, Clemens and Abdellaoui, Abdel and Warren, Helen and Vuckovic, gana and Mei, Hao and Bouchard, Claude and Perry, John and Cappellani, Stefania and Mirza, Saira and Benton, Miles C and Broeckel, Ulrich and Medland, Sarah Elizabeth and Lind, Penelope and Malerba, Giovanni and ng, Alexander and Yengo, Loic and Bielak, Lawrence F and Zhi, Degui and Most, Peter and Shriner, Daniel and Mägi, Reedik and Hemani, G and Karaderi, Tugce and Wang, Zhaoming and Liu, Tian and Demuth, Ilja and Zhao, Jing Hua and Meng, Weihua and Lataniotis, Lazaros and Van Der Laan, Sander W and Bradfield, Jonathan and Wood, Anew and Bonnefond, Amélie and Ahluwalia, Tarunveer Singh and Hall, Leanne M and Salvi, Erika and Yazar, Seyhan and Carstensen, Lisbeth and De Haan, Hugoline G and Abney, Mark and Afzal, Uzma and Allison, Matthew and Amin, Najaf and Asselbergs, Folkert W and Bakker, Stephan and Barr, Graham and Baumeister, Sebastian and Benjamin, Daniel J and Bergmann, Sven and Boerwinkle, Eric and Bottinger, Erwin P and Campbell, Archie and Chakravarti, Aravinda and Chan, Yingleong and Chanock, Stephen and Chen, Constance and Chen, Y.-D. Ida and ... and BioBank Japan Project and The BioBank Japan Project and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinsk genetik och genomik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature: international weekly journal of science, ISSN 0028-0836, 07/2015, Volume 523, Issue 7561, pp. 459 - 462
textabstractHomozygosity has long been associated with rare, often devastating, Mendelian disorders, and Darwin was one of the first to recognize that... 
INTELLIGENCE | HOMOZYGOSITY | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | GENETIC-VARIANTS | TRAITS | ASSOCIATION | BLOOD-PRESSURE | Studies | Cognition & reasoning | Disease | Genomics | Cognitive ability | Genomes | Educational attainment | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
by Perry, John and Day, Felix and Elks, Cathy and Sulem, Patrick and Thompson, Deborah and Ferreira, Teresa and He, Chunyan and Chasman, Daniel and Esko, Tõnu and Thorleifsson, Gudmar and Albrecht, Eva and Ang, Wei and Corre, Tanguy and Cousminer, Diana and Feenstra, Bjarke and Franceschini, Nora and Ganna, Anea and Johnson, Anew and Kjellqvist, Sanela and Lunetta, Kathryn and Mcmahon, George and Nolte, Ilja and Paternoster, Lavinia and Porcu, Eleonora and Smith, G.D and Stolk, Lisette and Teumer, Alexander and Tsernikova, Natalia and Tikkanen, Emmi and Ulivi, Shelia and Wagner, Erin K and Amin, Najaf and Bierut, Laura and Byrne, Enda and Hottenga, Jouke Jan and Koller, Daniel and Mangino, Massimo and Pers, Tune and Yerges-Armstrong, Laura and Zhao, Jing Hua and Anulis, Irene and Anton-Culver, Hoda and Atsma, Femke and Bandinelli, Stefania and Beckmann, Matthias W and Benítez, Javier and Blomqvist, Carl and Bojesen, Stig and Bolla, Manjeet and Bonnani, Bernardo and Brauch, Hiltrud and Brenner, Hermann and Buring, Julie and Chang-Claude, Jenny and Chanock, Stephen and Chen, Jinhui and Chenevix-Trench, Georgia and Collee, Margriet and Couch, Fergus and Couper, David and Coviello, Anea and Cox, Angela and Czene, Kamila and Adamo, Pio and Vivo, Immaculata and Demerath, Ellen and Dennis, Joe and Devilee, Peter and Dieffenbach, Aida Karina and Dunning, Alison and Eiriksdottir, Gudny and Hagen, Knut and Fasching, Peter and Ferrucci, Luigi and Flesch-Janys, Dieter and Flyger, Henrik and Foroud, Tatiana and Franke, Lude and Garcia, Melissa and García-Closas, Montserrat and Geller, Frank and De Geus, Eco E. J and Giles, Graham and Gudbjartsson, Daniel and Gudnason, Vilmundur and Guénel, Pascal and Guo, Suiqun and Hall, Per and Hamann, Ute and Haring, Robin and Hartman, Catharina and Heath, Anew and Hofman, Albert and Hooning, Maartje and Hopper, John and Hu, Frank and Hunter, David and Karasik, David and Kiel, Douglas P and Knight, Julia and ... and kConFabt LifeLines Cohort Study and InterAct Consortium and Australian Ovarian Canc Study and Early Growth Genetics EGG Consorti and GENICA Network and Australian Ovarian Cancer Study and kConFab and LifeLines Cohort Study and Early Growth Genetics (EGG) Consortium and The GENICA Network and The InterAct Consortium and The LifeLines Cohort Study and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature: international weekly journal of science, ISSN 0028-0836, 10/2014, Volume 514, Issue 7520, pp. 92 - 97
textabstractAge at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with... 
CELLS | METAANALYSIS | VARIANTS | CENTRAL PRECOCIOUS PUBERTY | BREAST-CANCER RISK | MULTIDISCIPLINARY SCIENCES | DISEASE | GENE-EXPRESSION | HUMAN PREFRONTAL CORTEX | WIDE ASSOCIATION | REVEALS | Age Factors | Diabetes Mellitus, Type 2 - genetics | Humans | Genetic Loci - genetics | Parents | Male | Cardiovascular Diseases - genetics | Obesity - genetics | Europe - ethnology | Female | Ribonucleoproteins - genetics | Hypothalamo-Hypophyseal System - physiology | Child | Body Mass Index | Genome-Wide Association Study | Membrane Proteins - genetics | Menarche - genetics | Intercellular Signaling Peptides and Proteins - genetics | Potassium Channels, Tandem Pore Domain - genetics | Ovary - physiology | Receptors, Retinoic Acid - metabolism | Genomic Imprinting - genetics | Proteins - genetics | Breast Neoplasms - genetics | Adolescent | Alleles | Polymorphism, Single Nucleotide - genetics | Quantitative Trait Loci - genetics | Receptors, GABA-B - metabolism | Allelomorphism | Menarche | Physiological aspects | Genome-wide association studies | Genetic aspects | Vitamin A | Puberty | Menstruation | Acids | Genomes | Mutation | Chromosomes | Girls | Age | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
Journal Article
by Joshi, Peter K and Esko, Tonu and Mattsson, Hannele and Eklund, Niina and Gandin, Ilaria and Nutile, Teresa and Jackson, Anne U and Schurmann, Claudia and Smith, Albert V and Zhang, Weihua and Okada, Yukinori and Stancakova, Alena and Faul, Jessica D and Zhao, Wei and Bartz, Traci M and Concas, Maria Pina and Franceschini, Nora and Enroth, Stefan and Vitart, Veronique and Trompet, Stella and Guo, Xiuqing and Chasman, Daniel I and O'Connel, Jeffrey R and Corre, Tanguy and Nongmaithem, Suraj S and Chen, Yuning and Mangino, Massimo and Ruggiero, Daniela and Traglia, Michela and Farmaki, Aliki-Eleni and Kacprowski, Tim and Bjonnes, Anew and van der Spek, Ashley and Wu, Ying and Giri, Anil K and Yanek, Lisa R and Wang, Lihua and Hofer, Edith and Rietveld, Cornelius A and McLeod, Olga and Cornelis, Marilyn C and Pattaro, Cristian and Verweij, Niek and Baumbach, Clemens and Abdellaoui, Abdel and Warren, Helen R and Vuckovic, gana and Mei, Hao and Bouchard, Claude and Perry, John R. B and Cappellani, Stefania and Mirza, Saira S and Benton, Miles C and Broeckel, Ulrich and Medland, Sarah E and Lind, PenelopeA and Malerba, Giovanni and ng, Alexander and Yengo, Loic and Bielak, Lawrence F and Zhi, Degui and van der Most, Peter J and Shriner, Daniel and Maegi, Reedik and Hemani, Gibran and Karaderi, Tugce and Wang, Zhaoming and Liu, Tian and Demuth, Ilja and Zhao, Jing Hua and Meng, Weihua and Lataniotis, Lazaros and van der Laan, Sander W and Bradfield, Jonathan P and Wood, Anew R and Bonnefond, Amelie and Ahluwalia, Tarunveer S and Hall, LeanneM and Salvi, Erika and Yazar, Seyhan and Carstensen, Lisbeth and de Haan, Hugoline G and Abney, Mark and Afzal, Uzma and Allison, Matthew A and Amin, Najaf and Asselbergs, Folkert W and Bakker, Stephan J. L and Barr, R. Graham and Baumeister, Sebastian E and Benjamin, Daniel J and Bergmann, Sven and Boerwinkle, Eric and Bottinger, Erwin P and Campbell, Archie and Chakravarti, Aravinda and Chan, Yingleong and Chanock, Stephen J and Chen, Constance and Chen, Y. -D. Ida and ...
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7561, pp. 459 - U176
Homozygosity has long been associated with rare, often devastating, Mendelian disorders(1), and Darwin was one of the first to recognize that inbreeding... 
Journal Article
by Surakka, Ida and Horikoshi, Momoko and Mägi, Reedik and Sarin, A.-P and Mahajan, Anubha and Lagou, Vasiliki and Marullo, Letizia and Ferreira, Teresa and Miraglio, Benjamin and Timonen, Sanna and Kettunen, Johannes and Pirinen, Matti and Karjalainen, Juha and Thorleifsson, Gudmar and Hägg, Sara and Hottenga, Jouke Jan and Isaacs, Aaron and Ladenvall, Claes and Beekman, Marian and Esko, Tõnu and Ried, Janina and Nelson, Christopher P and Willenborg, Christina and Gustafsson, Stefan and Westra, Harm-Jan and Blades, Matthew and De Craen, Anton J. M and Geus, Eco and Deelen, Joris and Grallert, Harald and Hamsten, Anders and Havulinna, Aki and Hengstenberg, Christian and Houwing-Duistermaat, Jeanine and Hypponen, Elina and Karssen, Lennart and Lehtimäki, Terho and Lyssenko, Valeriya and Magnusson, Patrik and Mihailov, Evelin and Müller-Nurasyid, Martina and Mpindi, John-Patrick and Pedersen, Nancy L and Penninx, Brenda and Perola, Markus and Pers, Tune and Peters, Annette and Rung, Johan and Smit, Johannes H and Steinthorsdottir, Valgerdur and Tobin, Martin and Tsernikova, Natalia and Leeuwen, Elisa and Viikari, Jorma and Willems, Sara and Willemsen, Gonneke and Schunkert, Heribert and Erdmann, Jeanette and Samani, Nilesh and Kaprio, Jaakko and Lind, Lars and Gieger, Christian and Metspalu, Anes and Eline Slagboom, P and Groop, Leif and Duijn, Cock and Eriksson, Johan G and Jula, Antti and Salomaa, Veikko and Boomsma, Dorret and Power, Christopher and Raitakari, Olli T and Ingelsson, Erik and Jarvelin, Marjo-Riitta and Thorsteinsdottir, Unnur and Franke, Lude and Ikonen, Elina and Kallioniemi, Olli and Pietiäinen, Vilja and Lindgren, Cecilia M and Zwart, John-Anker and Palotie, Aarno and McCarthy, Mark and Morris, Anew and Prokopenko, Inga and Ripatti, Samuli and ENGAGE Consortium and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature Genetics, ISSN 1061-4036, 01/2015, Volume 47, Issue 6, pp. 589 - 597
Journal Article
by Hoggart, Clive J and Venturini, Giulia and Mangino, Massimo and Gomez, Felicia and Ascari, Giulia and Zhao, Jing Hua and Teumer, Alexander and Winkler, Thomas W and Tšernikova, Natalia and Luan, Jian'an and Mihailov, Evelin and Ehret, Georg B and Zhang, Weihua and Lamparter, David and Esko, Tõnu and Macé, Aurelien and Rüeger, Sina and Bochud, Pierre-Yves and Barcella, Matteo and Dauvilliers, Yves and Benyamin, Beben and Evans, David M and Hayward, Caroline and Lopez, Mary F and Franke, Lude and Russo, Alessia and Heid, Iris M and Salvi, Erika and Vendantam, Sailaja and Arking, Dan E and Boerwinkle, Eric and Chambers, John C and Fiorito, Giovanni and Grallert, Harald and Guarrera, Simonetta and Homuth, Georg and Huffman, Jennifer E and Porteous, David and Moradpour, Darius and Iranzo, Alex and Hebebrand, Johannes and Kemp, John P and Lammers, Gert J and Aubert, Vincent and Heim, Markus H and Martin, Nicholas G and Montgomery, Grant W and Peraita-Aados, Rosa and Santamaria, Joan and Negro, Francesco and Schmidt, Carsten O and Scott, Robert A and Spector, Tim D and Strauch, Konstantin and Völzke, Henry and Wareham, Nicholas J and Yuan, Wei and Bell, Jordana T and Chakravarti, Aravinda and Kooner, Jaspal S and Peters, Annette and Matullo, Giuseppe and Wallaschofski, Henri and Whitfield, John B and Paccaud, Fred and Vollenweider, Peter and Bergmann, Sven and Beckmann, Jacques S and Tafti, Mehdi and Hastie, Nicholas D and Cusi, Daniele and Bochud, Murielle and Frayling, Timothy M and Metspalu, Anes and Jarvelin, Marjo-Riitta and Scherag, Ané and Smith, George Davey and Borecki, Ingrid B and Rousson, Valentin and Hirschhorn, Joel N and Rivolta, Carlo and Loos, Ruth J. F and Kutalik, Zoltán and de Bakker, P and Bültmann, U and Geleijnse, M and Harst, P. v d and Koppelman, G and Rosmalen, J. G. M and van Rossum, L and Smidt, H and Swertz, M. A and Stolk, R. P and Alizadeh, B and de Boer, R and Boezen, H. M and Bruinenberg, M and Franke, L and van der Harst, P and Hillege, H and ... and LifeLines Cohort Study and GIANT Consortium and Generation Scotland Consortium and LifeLines Cohort study and The LifeLines Cohort study and The GIANT Consortium
PLoS genetics, ISSN 1553-7390, 2014, Volume 10, Issue 7, pp. e1004508 - 12
Journal Article
PLOS Genetics, ISSN 1553-7390, 2014, Volume 10, p. e1004508
The phenotypic effect of some single nucleotide polymorphisms (SNPs) depends on their parental origin. We present a novel approach to detect parent-of-origin... 
Journal Article
by Joshi, P.K and Esko, T and Mattsson, H and Eklund, N and Gandin, I and Nutile, T and Jackson, A.U and Schurmann, C and Smith, A.V and Zhang, W and Okada, Y and Stancáková, A and Faul, J.D and Zhao, W and Bartz, T.M and Pina Concas, M and Franceschini, N and Enroth, S and Vitart, V and Trompet, S and Guo, X and Chasman, D.I and O'Connel, J.R and Corre, T and Nongmaithem, S.S and Chen, Y and Mangino, M and Ruggiero, D and Traglia, M and Farmaki, A.-E and Kacprowski, T and Bjonnes, A and Spek, A and Wu, Y and Giri, A.K and Yanek, L.R and Wang, L and Hofer, E and Rietveld, C.A and McLeod, O and Cornelis, M.C and Pattaro, C and Verweij, N and Baumbach, C and Abdellaoui, A and Warren, H.R and Vuckovic, D and Mei, H and Bouchard, C and Perry, J.R.B and Cappellani, S and Mirza, S.S and Benton, M.C and Broeckel, U and Medland, S.E and Lind, P.A and Malerba, G and ng, A and Yengo, L and Bielak, L.F and Zhi, D and van der Most, P.J and Shriner, D and Mägi, R and Hemani, G and Karaderi, T and Wang, Z and Liu, T and Demuth, I and Zhao, J.H and Meng, W and Lataniotis, L and van der Laan, S.W and Brafdfield, J.P and Wood, A.R and Bonnefond, A and Ahluwalia, T.S and Hall, L.M and Salvi, E and Yazar, S and Carstensen, L and de Haan, H.G and Abney, M and Afzal, U and Allison, M.A and Amin, N and Asselbergs, F.W and Bakker, S.J.L and Barr, R.G and Baumeister, S.E and Benjamin, D.J and Bergmann, S and Boerwinkle, E and Bottinger, E.P and Campbell, A and Chakravarti, A and Chan, Y and Chanock, S.J and Chen, C and Chen, Y.D.I and ...
Nature, ISSN 0028-0836, 2015, Volume 523, Issue 7561, pp. 459 - 462
Homozygosity has long been associated with rare, often devastating, Mendelian disorders, and Darwin was one of the first to recognize that inbreeding reduces... 
Journal Article
by Perry, J.R and Day, F and Elks, C.E and Sulem, P and Thompson, D.J and Ferreira, T and He, C and Chasman, D.I and Esko, T and Thorleifsson, G and Albrecht, E and Ang, W.Q and Corre, T and Cousminer, D.L and Feenstra, B and Franceschini, N and Ganna, A and Johnson, A.D and Kjellqvist, S and Lunetta, K.L and McMahon, G and Nolte, I.M and Paternoster, L and Porcu, E and Smith, A.V and Stolk, L and Teumer, A and Tsernikova, N and Tikkanen, E and Ulivi, S and Wagner, E.K and Amin, N and Bierut, L.J and Byrne, E.M and Hottenga, J.J and Koller, D.L and Mangino, M and Pers, T.H and Yerges-Armstrong, L.M and Zhao, J and Anulis, I.L and Anton-Culver, H and Atsma, F and Bandinelli, S and Beckmann, M.W and Benitez, J and Blomqvist, C and Bojesen, S.E and Bolla, M.K and Bonanni, B and Brauch, H and Brenner, H and Buring, J.E and Chang-Claude, J and Chanock, S and Chen, J and Chenevix-Trench, G and Collee, J.M and Couch, F.J and Couper, D and Coviello, A.D and Cox, A and Czene, K and D'Adamo, P and Smith, G and Vivo, I. De and Demerath, E.W and Dennis, J and Devilee, P and Dieffenbach, A.K and Dunning, A.M and Eiriksdottir, G and Eriksson, J.G and Fasching, P.A and Ferrucci, L and Flesch-Janys, D and Flyger, H and Foroud, T and Franke, L and Garcia, M.E and Garcia-Closas, M and Geller, F and Geus, E.E. de and Giles, G.G and Gudbjartsson, D.F and Gudnason, V and Guenel, P and Guo, S and Hall, P and Hamann, U and Haring, R and Hartman, C.A and Heath, A.C and Hofman, A and Hooning, M.J and Hopper, J.L and Hu, F.B and Hunter, D.J and Karasik, D and Kiel, D.P and ...
Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7520, pp. 92 - 97
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 10/2013, Volume 27, Issue 10, pp. 915 - 920
Journal Article
Nature Genetics, ISSN 1061-4036, 2015, Volume 47, Issue 6, pp. 589 - 597
Using a genome-wide screen of 9.6 million genetic variants achieved through 1000 Genomes Project imputation in 62,166 samples, we identify association to lipid... 
Journal Article