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1. Full Text A Test in Context: Lipoprotein(a): Diagnosis, Prognosis, Controversies, and Emerging Therapies
by Tsimikas, Sotirios
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2017, Volume 69, Issue 6, pp. 692 - 711
cardiovascular disease | aortic stenosis | genome-wide association studies | therapy | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Prognosis | Humans | Risk Factors | Cardiovascular Diseases - therapy | Cardiovascular Diseases - epidemiology | Lipoprotein(a) - physiology | Cardiovascular Diseases - diagnosis | Medical research | Aortic valve stenosis | Low density lipoproteins | Genomics | Apolipoproteins | Coronary heart disease | Epidemiology | Risk factors | Lipoprotein A | Cardiovascular agents | Atherosclerosis | Medicine, Experimental | Single nucleotide polymorphisms | Plasma | Rodents | Chemical bonds | Lipids | Low density lipoprotein | Binding sites | Cholesterol | Index Medicus | Abridged Index Medicus
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2. Full Text RNA-targeted therapeutics for lipid disorders
by Tsimikas, Sotirios
Current opinion in lipidology, ISSN 0957-9672, 12/2018, Volume 29, Issue 6, pp. 460 - 467
Biochemistry & Molecular Biology | Endocrinology & Metabolism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Lipid Metabolism Disorders - metabolism | Humans | Lipid Metabolism Disorders - genetics | Molecular Targeted Therapy - methods | Lipid Metabolism Disorders - drug therapy | RNA - metabolism | Care and treatment | Research | RNA | Hyperlipidemia | Low density lipoproteins
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3. Full Text Potential Causality and Emerging Medical Therapies for Lipoprotein(a) and Its Associated Oxidized Phospholipids in Calcific Aortic Valve Stenosis
by Tsimikas, Sotirios
Circulation research, ISSN 0009-7330, 02/2019, Volume 124, Issue 3, pp. 405 - 415
cell membranes | aortic valve | prevalence | phospholipids | lipoprotein(a) | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Heart Valve Prosthesis Implantation | Oxidation-Reduction | Humans | Risk Factors | Clinical Trials as Topic | Aortic Valve Stenosis - therapy | Calcinosis - therapy | Lipoprotein(a) | Calcinosis - etiology | Aortic Valve Stenosis - etiology | Hyperlipoproteinemias - complications | Phospholipids - metabolism | Causality | Aortic valve stenosis | Causes of | Physiological aspects | Development and progression | Phospholipids | Drug therapy | Health aspects | Lipoprotein A | Index Medicus | aortic stenosis | Atherosclerosis | oxidation | Pharmacology | Thrombosis
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4. In Search of Patients With Elevated Lp(a) Seek and Ye Shall Find
by Tsimikas, Sotirios
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2019, Volume 73, Issue 9, pp. 1040 - 1042
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Hyperlipidemias | Cholesterol, LDL | Lipoprotein(a) | Hyperlipoproteinemia Type II | Humans | Studies | Population | Cardiology | Medical screening | Statins | Cholesterol
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5. Full Text In search of a physiological function of lipoprotein(a): causality of elevated Lp(a) levels and reduced incidence of type 2 diabetes
by Tsimikas, Sotirios
Journal of lipid research, ISSN 0022-2275, 05/2018, Volume 59, Issue 5, pp. 741 - 744
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Index Medicus
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6. Full Text Lipoprotein(a): Novel target and emergence of novel therapies to lower cardiovascular disease risk
by Tsimikas, Sotirios
Current opinion in endocrinology, diabetes, and obesity, ISSN 1752-296X, 2016, Volume 23, Issue 2, pp. 157 - 164
Cardiovascular Disease | Lipoprotein(a) | Aortic Stenosis | Diabetes Mellitus | Antisense Oligonucleotides | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Dyslipidemias - genetics | Dyslipidemias - drug therapy | Risk Assessment | Cardiovascular Diseases - prevention & control | Down-Regulation | Humans | Risk Factors | Treatment Outcome | Biomarkers - blood | Proprotein Convertase 9 - metabolism | Molecular Targeted Therapy | Drug Discovery | Serine Proteinase Inhibitors - therapeutic use | Dyslipidemias - blood | Animals | Dyslipidemias - epidemiology | Proprotein Convertase 9 - antagonists & inhibitors | Oligonucleotides, Antisense - therapeutic use | Cardiovascular Diseases - epidemiology | Hypolipidemic Agents - therapeutic use | Lipoprotein(a) - blood | Lipoprotein(a) - genetics | Index Medicus
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7. Full Text In search of a physiological function of lipoprotein(a): causality of elevated Lp(a) levels and reduced incidence of type 2 diabetes1
by Tsimikas, Sotirios
Journal of lipid research, ISSN 0022-2275, 05/2018, Volume 59, Issue 5, pp. 741 - 744
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8. Full Text The re-emergence of lipoprotein(a) in a broader clinical arena
by Tsimikas, Sotirios
Progress in cardiovascular diseases, ISSN 0033-0620, 2016, Volume 59, Issue 2, pp. 135 - 144
Cardiovascular | Aortic stenosis | Therapy | Cardiovascular disease | Lipoprotein(a) | Genome-wide association studies | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Calcinosis - genetics | Aortic Valve Stenosis - genetics | Cardiovascular Diseases - prevention & control | Humans | Risk Factors | Aortic Valve Stenosis - therapy | Aortic Valve - metabolism | Aortic Valve - pathology | Calcinosis - therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Cardiovascular Diseases - epidemiology | Aortic Valve Stenosis - metabolism | Calcinosis - metabolism | Lipoprotein(a) - metabolism | Medication Therapy Management - trends | Drug approval | Low density lipoproteins | Lipoprotein A | Aortic valve stenosis | Genomics | Blood lipids | Apolipoproteins | Niacin | Risk factors | Statins | Cardiovascular agents
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9. Full Text Lipid-Lowering Agents: Targets Beyond PCSK9
by Hegele, Robert A and Tsimikas, Sotirios
Circulation research, ISSN 0009-7330, 02/2019, Volume 124, Issue 3, pp. 386 - 404
Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Physiological aspects | Genetic aspects | Dyslipidemias | Drug therapy | Antilipemic agents
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10. Full Text Oxidative Biomarkers in the Diagnosis and Prognosis of Cardiovascular Disease
by Tsimikas, Sotirios
The American journal of cardiology, ISSN 0002-9149, 2006, Volume 98, Issue 11, pp. S9 - S17
Prognosis | Oxidation-Reduction | Coronary Artery Disease - diagnosis | 1-Alkyl-2-acetylglycerophosphocholine Esterase - blood | Humans | Cholesterol, LDL - blood | Biomarkers - blood | Peroxidase - blood | Coronary Artery Disease - blood | Enzymes | Atherosclerosis | Oxidizing agents | Diagnosis | Blood lipids | Plant lipids | Cardiovascular diseases | Biological markers | Risk factors | Heart attack | Proteins | Cardiovascular disease | Lipids | Oxidation | Medical prognosis | Index Medicus | Abridged Index Medicus
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11. Full Text Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: A rationale for increased efforts to understand its pathophysiology and develop targeted therapies
by Tsimikas, Sotirios and Hall, Jennifer L
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2012, Volume 60, Issue 8, pp. 716 - 721
cardiovascular disease | therapy | Lp(a) | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | General aspects. Genetic counseling | Biological and medical sciences | Medical sciences | Medical genetics | Oxidative Stress | Atherosclerosis - genetics | Cardiovascular Diseases - drug therapy | Humans | Cardiovascular Diseases - genetics | Molecular Targeted Therapy - trends | Lipoprotein(a) - blood | Lipoprotein(a) - metabolism | Molecular Targeted Therapy - methods | Cardiovascular Diseases - physiopathology | European Continental Ancestry Group - genetics | Cardiovascular Diseases - metabolism | Risk Assessment | Atherosclerosis - physiopathology | Cholesterol, HDL - metabolism | Risk Factors | African Americans - genetics | Cholesterol, HDL - genetics | Hypolipidemic Agents - pharmacology | Cholesterol, LDL - genetics | Animals | Cholesterol, LDL - metabolism | Polymorphism, Single Nucleotide | Lipoprotein(a) - genetics | Apoptosis | Index Medicus | Abridged Index Medicus
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