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Journal of Investigative Dermatology, ISSN 0022-202X, 03/2019, Volume 139, Issue 3, pp. 514 - 517
Most susceptibility loci for complex dermatologic diseases fall within non-coding regions, making assignment of function difficult. Chromosome conformation... 
DERMATOLOGY
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1627, pp. 511 - 525
In the past decade, high-throughput techniques have facilitated the "-omics" research. Transcriptomic study, for instance, has advanced our understanding on... 
GEO | Data analysis | RNA-seq | Microarray | Transcriptomic | User-Computer Interface | Computational Biology - methods | Fibrosis - genetics | Humans | Gene Expression Regulation | Transcriptome | Databases, Genetic | Gene Expression Profiling | Research | Research Personnel | Search Engine | High-Throughput Nucleotide Sequencing | Software | Web Browser | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 08/2014, Volume 95, Issue 2, pp. 162 - 172
Journal Article
by Prins, B.P and Abbasi, A and Wong, A and Vaez, Ahmad and Nolte, Ilja and Franceschini, Nora and Stuart, P.E and Guterriez Achury, J and Mistry, V and Bradfield, Jonathan and Valdes, Ana Maria and Bras, Jose and Shatunov, Aleksey and Lu, Chao and Han, B and Raychaudhuri, Soumya and Bevan, Steve and Mayes, M.D and Tsoi, L.C and Evangelou, Evangelos and Nair, Rajan P and Grant, Struan and Polychronakos, Constantin and Radstake, Timothy and Heel, David and Dunstan, M.L and Wood, Nicholas and Al-Chalabi, Ammar and Dehghan, Abbas and Hakonarson, Hakon and Markus, H.S and Elder, James and Knight, J and Arking, Dan and Spector, Timothy and Koeleman, Bobby and Duijn, Cornelia and Martín, Javier and Morris, Anew and Weersma, Rinse K and Wijmenga, Cisca and Munroe, Patricia and Perry, John and Pouget, J.G and Jamshidi, Yalda and Snieder, Harold and Alizadeh, Behrooz and Inflammation Working Grp CHARGE Co and Autism Spectrum Disorder Working G and PAGE Consortium and Int Consortium Blood Pressure and Int Parkinson Dis Genomics Consort and Schizophrenia Working Grp Psychiat and DIAGRAM Consortium and CARDIoGRAMplusC4d Consortium and Int Stroke Genetics Consortium and Treat OA Consortium and ALS Consortium and CKDGen Consortium and Systemic Sclerosis Consortium and GERAD1 Consortium and International Consortium for Blood Pressure and International Stroke Genetics Consortium and Treat OA consortium and ALS consortium and CKDGen consortium and Schizophrenia Working Group of the Psychiatric Genomics Consortium and Systemic Sclerosis consortium and Inflammation Working Group of the CHARGE Consortium and International Parkinson’s Disease Genomics Consortium and CARDIoGRAMplusC4D Consortium and Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium
PLoS Medicine, ISSN 1549-1277, 06/2016, Volume 13, Issue 6, pp. e1001976 - e1001976
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 12/2015, Volume 97, Issue 6, pp. 816 - 836
Journal Article
by Tsoi, H and Lam, K.C and Dong, Y and Zhang, X and Lee, C.K and Zhang, J and Ng, S.C and Ng, S.S.M and Zheng, S and Chen, Y and Fang, J and Yu, J
Oncogene, ISSN 0950-9232, 11/2017, Volume 36, Issue 44, pp. 6109 - 6118
One characteristic of cancer cells is the abnormally high rate of cell metabolism to sustain their enhanced proliferation. However, the behind mechanism of... 
RNA-POLYMERASE-I | ACTIVATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | UPSTREAM BINDING-FACTOR | CELL BIOLOGY | INHIBITION | ONCOLOGY | SIGNALING PATHWAY | CALCIUM | GENETICS & HEREDITY | MDM2 | STRESS | Proto-Oncogene Proteins c-mdm2 - genetics | Calcium - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | RNA, Ribosomal - genetics | Tumor Suppressor Protein p53 - genetics | Gene Knockdown Techniques | Pol1 Transcription Initiation Complex Proteins - genetics | Pol1 Transcription Initiation Complex Proteins - metabolism | Female | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Cell Proliferation - genetics | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Ribosomal Proteins - genetics | HCT116 Cells | RNA, Ribosomal - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Disease-Free Survival | Protein Interaction Maps - genetics | Aged | Colorectal Neoplasms - pathology | Care and treatment | Colon cancer | Ribosomal RNA | Cancer cells | Cell cycle | Diagnosis | Research | Protein kinases | Cell proliferation | Transcription | Pathogenesis | p53 Protein | Colorectal carcinoma | Colorectal cancer | Kinases | Calcium signalling | Cell growth | Calcium-binding protein | Colon | Calmodulin | MDM2 protein | Cell survival | RNA-mediated interference | rRNA 45S | Tumor cell lines | Metabolism | Ribonucleic acid--RNA | Protein L11 | Adenomatous polyposis coli | Ribosomal protein S6 kinase | Ribosomal protein L11 | Endoplasmic reticulum | Calcium (reticular) | Cytoplasm | Ca2+/calmodulin-dependent protein kinase II | Index Medicus | Original
Journal Article
The Journal of investigative dermatology, 12/2018
Psoriasis lesions are rich in IL-17-producing T-cells as well as neutrophils, which release webs of DNA-protein complexes known as neutrophil extracellular... 
Journal Article
Journal Article
Journal Article
by Tsoi, L.C and Spain, S.L and Knight, J and Ellinghaus, E and Stuart, P.E and Capon, F and Ding, J and Li, J and Tejasvi, T and Gudjonsson, J.E and Kang, H and Allen, M.H and McManus, R and Novelli, G and Samuelsson, L and Schalkwijk, J and Stahle, M and Burden, A.D and Smith, C.H and Cork, M.J and Estivill, X and Bowcock, A and Krueger, G.G and Weger, W and Worthington, J and Tazi-Ahnini, R and Nestle, F.O and Hayday, A and Hoffmann, P and Winkelmann, J and Wijmenga, C and Langford, C and Edkins, S and Anews, R and Blackburn, H and Strange, A and Band, G and Pearson, R and Vukcevic, D and Spencer, C.C and Deloukas, P and Mrowietz, U and Schreiber, S and Weidinger, S and Koks, S and Kingo, K and Esko, T and Metspalu, A and Lim, H.W and Voorhees, J.J and Weichenthal, M and Wichmann, H.E and Chanan, V and Rosen, C.F and Rahman, P and Gladman, D.D and Griffiths, C.E and Reis, A and Kere, J and Duffin, K.C and Helms, C and Goldgar, D and Li, Y and Paschall, J and Malloy, M.J and Pullinger, C.R and Kane, J.P and Gardner, J and Perlmutter, A and Miner, A and Feng, B.J and Hiremagalore, R and Ike, R.W and Christophers, E and Henseler, T and Ruether, A and Schrodi, S.J and Prahalad, S and Guthery, S.L and Hiregalore, R and Donnelly, P and Collaborative Assoc Study Psoriasi and Psoriasis Assoc Genetics Extension and Genetic Anal Psoriasis Consortium and Wellcome Trust Case Control Consor and Psoriasis Association Genetics Extension and Genetic Analysis of Psoriasis Consortium and Collaborative Association Study of Psoriasis (CASP) and Wellcome Trust Case Control Consortium 2 and Sahlgrenska akademin and Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik and Göteborgs universitet and Gothenburg University and Institute of Biomedicine, Department of Medical and Clinical Genetics and Sahlgrenska Academy
Nature Genetics, ISSN 1061-4036, 2012, Volume 44, Issue 12, pp. 1341 - 1348
To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2 independent... 
COMMON VARIANTS | SIGNALING PATHWAYS | MULTIPLE COMMON | INTERFERON-GAMMA | TH17 DIFFERENTIATION | GENETICS & HEREDITY | GENE-EXPRESSION | T-CELL DEVELOPMENT | GENOME-WIDE ASSOCIATION | CELIAC-DISEASE | NEGATIVE REGULATOR | Oligonucleotide Array Sequence Analysis | Humans | Immunity, Innate - genetics | Genetic Loci | CARD Signaling Adaptor Proteins - genetics | Psoriasis - genetics | Core Binding Factor Alpha 3 Subunit - immunology | STAT3 Transcription Factor - genetics | Skin - immunology | Psoriasis - immunology | CARD Signaling Adaptor Proteins - immunology | DEAD Box Protein 58 | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Guanylate Cyclase - immunology | Membrane Proteins - genetics | Membrane Proteins - immunology | GTPase-Activating Proteins - immunology | DEAD-box RNA Helicases - genetics | Core Binding Factor Alpha 3 Subunit - genetics | DEAD-box RNA Helicases - immunology | Guanylate Cyclase - genetics | T-Lymphocytes - immunology | Polymorphism, Single Nucleotide | GTPase-Activating Proteins - genetics | STAT3 Transcription Factor - immunology | Psoriasis | Physiological aspects | Disease susceptibility | Genetic aspects | Research | Autoimmune diseases | Gene expression | Chromosomes | Risk factors | Index Medicus | genetic analysis | innate immunity | Dermatologi och venereologi | Dermatology and Venereal Diseases | psoriasis
Journal Article