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1. Geometry, dynamics, and foliations 2013
: in honor of Steven Hurder and Takashi Tsuboi on the occasion of their 60th birthdays
by Hurder, Steve. honouree and Tsuboi, Takashi. honouree and Asuke, Taro. editor and Matsumoto, Shigenori, 1947- editor and Mitsumatsu, Yoshihiko. editor and Nihon Sūgakkai
2017, Volume 72.
Foliations (Mathematics) | Dynamics
Conference Proceeding
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2. Full Text Can Kampo and Dietary Supplement Address Unmet Need? – A Commentary on Tatsumi et al. and Hoffmann et al
by Tsuboi, Takashi
Pharmacopsychiatry, ISSN 0176-3679, 11/2019, Volume 52, Issue 6, pp. 280 - 281
Commentary | PHARMACOLOGY & PHARMACY | FRAILTY | PSYCHIATRY | OLDER-ADULTS | OMEGA-3-FATTY-ACIDS
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3. Full Text BRET based dual-colour (visible/near-infrared) molecular imaging using a quantum dot/EGFP–luciferase conjugate
by Tsuboi, Setsuko and Jin, Takashi
RSC Advances, ISSN 2046-2069, 10/2019, Volume 9, Issue 60, pp. 34964 - 34971
Owing to its high sensitivity, bioluminescence imaging is an important tool for biosensing and bioimaging in life sciences. Compared to fluorescence imaging,... 
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4. Recombinant Protein (Luciferase-IgG Binding Domain) Conjugated Quantum Dots for BRET-Coupled Near-Infrared Imaging of Epidermal Growth Factor Receptors
by Setsuko Tsuboi and Takashi Jin
Bioconjugate Chemistry, ISSN 1043-1802, 04/2018, Volume 29, Issue 4, p. 1466
For the highly sensitive near-infrared (NIR) optical detection of epidermal growth factor receptors (EGFRs) expressed on cancer cells, bioluminescence... 
Bioluminescence | Immunoglobulin G | Emission | Fluorescence | Proteins | Receptors | Epidermal growth factor | Infrared imaging | Infrared imaging systems | Glutathione | Recombinant | Binding | Epidermal growth factor receptors | Quantum dots | Protein G | I.R. radiation | Growth factor receptors | Molecular chains | Emissions | Luciferin | Monoclonal antibodies | Conjugation | Energy transfer | Functional groups | Cancer
Journal Article
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5. Full Text Bioluminescence Resonance Energy Transfer (BRET)‐coupled Annexin V‐functionalized Quantum Dots for Near‐Infrared Optical Detection of Apoptotic Cells
by Tsuboi, Setsuko and Jin, Takashi
ChemBioChem, ISSN 1439-4227, 11/2017, Volume 18, Issue 22, pp. 2231 - 2235
Deregulation in apoptosis induces numerous diseases such as cancer, cardiovascular, and neurodegenerative diseases. Detection of apoptotic cells is crucial for... 
energy transfer | quantum dots | apoptosis | near-infrared | bioluminescence | Quantum Dots | Spectroscopy, Near-Infrared | Humans | Annexin A5 - chemistry | Cell Line, Tumor | Bioluminescence Resonance Energy Transfer Techniques | Apoptosis | Development and progression | Nervous system diseases | Usage | Annexins
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6. Can Kampo and Dietary Supplement Address Unmet Need? - A Commentary on Tatsumi et al. and Hoffmann et al
by Tsuboi, Takashi
Pharmacopsychiatry, 05/2019
Journal Article
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7. Full Text Corrigendum: Bioluminescence Resonance Energy Transfer (BRET)-coupled Annexin V-functionalized Quantum Dots for Near-Infrared Optical Detection of Apoptotic Cells
by Tsuboi, Setsuko and Jin, Takashi
ChemBioChem, ISSN 1439-4227, 10/2018
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8. Full Text Efficacy of long‐term treatment with efinaconazole 10% solution in patients with onychomycosis, including severe cases: A multicenter, single‐arm study
by Iozumi, Ken and Abe, Masatoshi and Ito, Yoshiko and Uesugi, Takashi and Onoduka, Takashi and Kato, Ichiro and Kato, Fumihiro and Kodama, Kazuo and Takahashi, Hidetoshi and Takeda, Osamu and Tomizawa, Koki and Nomiyama, Tomoko and Fujii, Mizue and Mayama, Jun and Muramoto, Fumio and Yasuda, Hidemi and Yamanaka, Kiyomitsu and Sato, Tomotaka and Oh‐i, Tsunao and Kasai, Hiroko and Tsuboi, Ryoji and Hattori, Naoko and Maruyama, Ryuji and Omi, Tokuya and Shimoyama, Harunari and Sei, Yoshihiro and Nakasu, Ichiro and Nishimoto, Shuhei and Hata, Yasuki and Mochizuki, Takashi and Fukuzawa, Masao and Seishima, Mariko and Sugiura, Kazumitsu and Katayama, Ichiro and Yamamoto, Osamu and Shindo, Masahisa and Kiryu, Hiroe and Kusuhara, Masahiro and Takenaka, Motoi and Watanabe, Shinichi
The Journal of Dermatology, ISSN 0385-2407, 08/2019, Volume 46, Issue 8, pp. 641 - 651
We evaluated the efficacy of efinaconazole 10% topical solution in long‐term use, for up to 72 weeks, for onychomycosis, including severe cases. Among 605... 
efinaconazole | onychomycosis | long‐term observation | topical triazole antifungal | severe case | long-term observation | NAIL LACQUER | MANAGEMENT | DEBRIDEMENT | RANDOMIZED-TRIAL | ITRACONAZOLE | DERMATOLOGY | AMOROLFINE | THERAPY | ASSOCIATION | Mycoses | Complications and side effects | Care and treatment | Onychomycosis | Toenail | Clinical trials | Fungal infections | Drug therapy | Patients | Quality of life | Original
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9. Full Text Fluorescent, Recombinant-Protein-Conjugated, Near-Infrared-Emitting Quantum Dots for in Vitro and inVivo Dual-Color Molecular Imaging
by Tsuboi, Setsuko and Jin, Takashi
ChemBioChem, ISSN 1439-4227, 02/2019, Volume 20, Issue 4, pp. 568 - 575
Near-infrared (NIR)-emitting fluorescent probes are widely used for molecular imaging at the whole-body level. However, NIR-emitting fluorescent probes... 
Fluorescence | Recombinant proteins | Immunoglobulin G | Fluorescence microscopy | Protein binding | Immunoglobulins | Quantum dots | Protein G | Color | Protein biosynthesis | Breast cancer | Fluorescent indicators | Proteins | Green fluorescent protein | Infrared imaging | Chemical synthesis | Microscopes | Probes | Recombinant
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10. Full Text Corrigendum: Bioluminescence Resonance Energy Transfer (BRET)‐coupled Annexin V‐functionalized Quantum Dots for Near‐Infrared Optical Detection of Apoptotic Cells
by Tsuboi, Setsuko and Jin, Takashi
ChemBioChem, ISSN 1439-4227, 10/2018, Volume 19, Issue 20, pp. 2242 - 2242
energy transfer | quantum dots | apoptosis | near-infrared | bioluminescence | Annexins | Apoptosis | Bioluminescence | Annexin V | Quantum dots | Energy transfer
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11. Full Text Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells
by Unoki, Takamitsu and Abiko, Yumi and Toyama, Takashi and Uehara, Takashi and Tsuboi, Koji and Nishida, Motohiro and Kaji, Toshiyuki and Kumagai, Yoshito
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, pp. 28944 - 28944
Methylmercury (MeHg) modifies cellular proteins via their thiol groups in a process referred to as "S-mercuration", potentially resulting in modulation of the... 
APOPTOSIS | IN-VITRO | INHIBITION | AKT ACTIVATION | MULTIDISCIPLINARY SCIENCES | REVERSIBLE OXIDATION | ELEMENT-BINDING PROTEIN | S-MERCURATION | CHEMICAL-MODIFICATION | TUMOR-SUPPRESSOR PTEN | 1,2-NAPHTHOQUINONE | Index Medicus
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12. Full Text Case of acute anterior uveitis and Vogt–Koyanagi–Harada syndrome‐like eruptions induced by nivolumab in a melanoma patient
by Arai, Takashi and Harada, Kazutoshi and Usui, Yoshihiko and Irisawa, Ryokichi and Tsuboi, Ryoji
The Journal of Dermatology, ISSN 0385-2407, 08/2017, Volume 44, Issue 8, pp. 975 - 976
ASSOCIATION | DISEASE | DERMATOLOGY | Melanoma | Eruptions | Uveitis
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13. A case of infection-related glomerulonephritis with massive eosinophilic infiltration
by Okabe, Masahiro and Takamura, Tsuyoshi and Tajiri, Akiko and Tsuboi, Nobuo and Ishikawa, Masahiro and Ogura, Makoto and Ohashi, Ryuji and Oda, Takashi and Yokoo, Takashi
Clinical Nephrology, ISSN 0301-0430, 08/2018, Volume 90, Issue 2, pp. 142 - 147
Infection-related glomerulonephritis (IRGN) is rarely complicated with eosinophil infiltration into the glomerulus. Here we report a case of eosinophilic... 
Nephritis-associated plasmin receptor | Vasculitis | Infection-related glomerulonephritis | Eosinophilia | Tubulointerstitial nephritis | vasculitis | STREPTOCOCCAL INFECTION | nephritis-associated plasmin receptor | CHILDREN | ACUTE POSTSTREPTOCOCCAL GLOMERULONEPHRITIS | infection-related glomerulonephritis | tubulointerstitial nephritis | PLASMIN RECEPTOR | NEPHRITIS | UROLOGY & NEPHROLOGY | eosinophilia | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | ANTIGEN
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14. Full Text Gliotransmitter release from astrocytes: Functional, developmental, and pathological implications in the brain
by Harada, Kazuki and Kamiya, Taichi and Tsuboi, Takashi
Frontiers in Neuroscience, ISSN 1662-4548, 2016, Volume 9, p. 499
Astrocytes comprise a large population of cells in the brain and are important partners to neighboring neurons, vascular cells, and other glial cells.... 
Glial cell | Astrocytes | Gliotransmitter | Optical imaging | Exocytosis | Neurodevelopmental disorders | Synaptic activity | GLUTAMATE RELEASE | ALZHEIMERS-DISEASE | PLASMINOGEN-ACTIVATOR GENE | AMYLOID PLAQUES | CALCIUM WAVES | synaptic activity | gliotransmitter | ASPARTATE NMDA RECEPTOR | neurodevelopmental disorders | NEUROSCIENCES | TRANSMITTER RELEASE | glial cell | DENDRITE GROWTH | D-SERINE | optical imaging | IN-VIVO | exocytosis | astrocytes | Brain | Analysis | Environmental aspects | Nervous system | Degeneration | Research | Risk factors | Neuroimaging | Plasma | Animal models | Neurons | D-Serine | Glial cells | Neuronal-glial interactions | Proteins | Toxicology | Neurotransmitters | Molecular modelling | Blood-brain barrier | Microscopy | Neural networks | Morphology | Information processing | Capillaries
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15. Full Text Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder
by Takata, Atsushi and Miyake, Noriko and Tsurusaki, Yoshinori and Fukai, Ryoko and Miyatake, Satoko and Koshimizu, Eriko and Kushima, Itaru and Okada, Takashi and Morikawa, Mako and Uno, Yota and Ishizuka, Kanako and Nakamura, Takumi and Nakamura, Kazuyuki and Nakamura, Kazuhiko and Tsujii, Masatsugu and Yoshikawa, Takeo and Toyota, Tomoko and Okamoto, Nobuhiko and Hiraki, Yoko and Hashimoto, Ryota and Yasuda, Yuka and Saitoh, Shinji and Ohashi, Kei and Sakai, Yasunari and Ohga, Shouichi and Hara, Toshiro and Kato, Tadafumi and Kato, Mitsuhiro and Ito, Aiko and Seiwa, Chizuru and Shirahata, Emi and Osaka, Hitoshi and Matsumoto, Naomichi and Matsumoto, Ayumi and Takeshita, Saoko and Tohyama, Jun and Saikusa, Tomoko and Matsuishi, Toyojiro and Tsuboi, Takashi and Suzuki, Toshifumi and Saitsu, Hirotomo and Nakashima, Mitsuko and Mizuguchi, Takeshi and Tanaka, Fumiaki and Mori, Norio and Ozaki, Norio
Cell Reports, ISSN 2211-1247, 01/2018, Volume 22, Issue 3, pp. 734 - 747
Recent studies have established important roles of mutations (DNMs) in autism spectrum disorders (ASDs). Here, we analyze DNMs in 262 ASD probands of Japanese... 
ASD | GGNBP2 | striatum | AGO1 | de novo mutations | ATP1A3 | ATP2B2 | MCM6 | cardiac glycosides | cerebellum | SIGNATURES | VARIANTS | TRANSLATIONAL PROFILING APPROACH | GENES | RISK | PREVALENCE | GENOME | CHILDREN | CELL BIOLOGY | Autism Spectrum Disorder - genetics | Genetic Predisposition to Disease | Autism Spectrum Disorder - pathology | Mutation - genetics | Humans
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16. Full Text Malassezia species and their associated skin diseases
by Harada, Kazutoshi and Saito, Mami and Sugita, Takashi and Tsuboi, Ryoji
The Journal of Dermatology, ISSN 0385-2407, 03/2015, Volume 42, Issue 3, pp. 250 - 257
Malassezia spp. are lipophilic fungi that occur on all skin surfaces of humans and animals as commensal and pathogenic organisms. In the 2000s, several new... 
seborrheic dermatitis | atopic dermatitis | Malassezia | pityriasis versicolor | Malassezia folliculitis | ASSISTED LASER-DESORPTION | PITYRIASIS-VERSICOLOR | HEALTHY-SUBJECTS | ATOPIC-DERMATITIS PATIENTS | IONIZATION-TIME | HUMAN KERATINOCYTES | MOLECULAR ANALYSIS | DERMATOLOGY | FLIGHT MASS-SPECTROMETRY | PITYROSPORUM FOLLICULITIS | Dermatitis, Seborrheic - microbiology | Humans | Dermatitis, Atopic - microbiology | Folliculitis - microbiology | Tinea Versicolor - microbiology | Tinea Versicolor - pathology | Atopic dermatitis | Skin | Skin diseases | Dermatitis | Medical treatment
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17. Full Text The behavioral paradigm to induce repeated social defeats in zebrafish
by Nakajo, Haruna and Tsuboi, Takashi and Okamoto, Hitoshi
Neuroscience Research, ISSN 0168-0102, 11/2019
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18. BRET based dual-colour (visible/near-infrared) molecular imaging using a quantum dot/EGFP–luciferase conjugate (Electronic supplementary information (ESI) available: Experimental details and supporting figures. See DOI: 10.1039/c9ra07011g)
by Setsuko Tsuboi and Takashi Jin
RSC Advances, 01/2019, Volume 9, Issue 60, pp. 34964 - 34971
Owing to its high sensitivity, bioluminescence imaging is an important tool for biosensing and bioimaging in life sciences. Compared to fluorescence imaging,... 
Proteins | Conjugates | Receptors | Bioluminescence | Medical imaging | Quantum dots | Color | Infrared imaging | Antibodies | Fluorescence | Energy transfer
Journal Article
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19. Full Text Homeomorphism groups of commutator width one
by Takashi Tsuboi
Proceedings of the American Mathematical Society, ISSN 0002-9939, 05/2013, Volume 141, Issue 5, pp. 1839 - 1847
can be written as one commutator.]]> 
Homeomorphism group | Commutator subgroup | Uniformly perfect | DIFFEOMORPHISMS | MATHEMATICS | MATHEMATICS, APPLIED | uniformly perfect | SIMPLICITY | commutator subgroup | MANIFOLDS
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20. Full Text The opportunistic yeast pathogen Trichosporon asahii colonizes the skin of healthy individuals: analysis of 380 healthy individuals by age and gender using a nested polymerase chain reaction assay
by Zhang, Enshi and Sugita, Takashi and Tsuboi, Ryoji and Yamazaki, Takashi and Makimura, Koichi
Microbiology and Immunology, ISSN 0385-5600, 07/2011, Volume 55, Issue 7, pp. 483 - 488
ABSTRACT Deep‐seated trichosporonosis is an opportunistic fungal infection with a poor prognosis and high mortality rate. The major causative agent is... 
microbiota | skin | Trichosporon asahii | Microbiota | Skin | CUTANEUM | INFECTIONS | HYPERSENSITIVITY PNEUMONITIS | SUSCEPTIBILITY | ATOPIC-DERMATITIS PATIENTS | MALASSEZIA MICROFLORA | MICROBIOLOGY | IMMUNOLOGY | MOLECULAR ANALYSIS | LOUBIERI | REGIONS | INTERGENIC SPACER-1 | Carrier State - epidemiology | Prevalence | Skin - microbiology | Age Factors | DNA, Fungal - genetics | Humans | Middle Aged | Carrier State - microbiology | Child, Preschool | Infant | Male | Trichosporon - classification | Polymerase Chain Reaction - methods | Trichosporon - genetics | Young Adult | DNA, Ribosomal Spacer - genetics | Aged, 80 and over | Adult | Female | Child | Infant, Newborn | Mycological Typing Techniques | Japan | Genotype | Adolescent | Sex Factors | Trichosporon - isolation & purification | Aged
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