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Lancet Respiratory Medicine, The, ISSN 2213-2600, 2017, Volume 5, Issue 1, pp. 42 - 50
Journal Article
Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 12, pp. 2636 - 2642
Journal Article
Juntendo Medical Journal(2013-), ISSN 2187-9737, 2018, Volume 64, Issue 3, pp. 191 - 197
Next generation sequencing-based cancer genome analysis has been widely performed in basic research as well as clinical trials. Datasets with comprehensive... 
Journal Article
Genome Biology, ISSN 1474-7596, 04/2015, Volume 16, Issue 1, p. 66
Background: To understand the heterogeneous behaviors of individual cancer cells, it is essential to investigate gene expression levels as well as their... 
RET | TRANSCRIPTOME | RNA-SEQ | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HUMAN HOUSEKEEPING GENES | GENETICS & HEREDITY | FRAMEWORK | IDENTIFICATION | CCDC6-RET FUSION | CANCER | SOMATIC MUTATIONS | GENOME | Proto-Oncogene Proteins c-ret - metabolism | Adenocarcinoma of Lung | Cytoskeletal Proteins - genetics | Humans | Lung Neoplasms - metabolism | ErbB Receptors - genetics | Gene Expression Regulation, Neoplastic | Transcriptome | Gene Expression Profiling | RNA - genetics | Adenocarcinoma - metabolism | Piperidines - pharmacology | Cytoskeletal Proteins - metabolism | Adenocarcinoma - genetics | Single-Cell Analysis | Molecular Targeted Therapy - methods | Lung Neoplasms - genetics | ErbB Receptors - metabolism | Genes, Essential | Sequence Analysis, RNA | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Drug Delivery Systems - methods | Proto-Oncogene Proteins c-ret - genetics | Adenocarcinoma | Substance abuse treatment | Transcription | Genomics | Lung cancer | Genomes | Drug resistance | Kinases | Consortia | Ret protein | Next-generation sequencing | Plasticity | DNA methylation | Standard deviation | Trends | Bioinformatics | Protein-tyrosine kinase | Deoxyribonucleic acid--DNA | Tyrosine | Epidermal growth factor receptors | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Cell lines | Mutation | Research
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2014, Volume 289, Issue 30, pp. 20813 - 20823
Journal Article
British Journal of Cancer, ISSN 0007-0920, 11/2017, Volume 117, Issue 10, pp. 1450 - 1458
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0198219
Arctigenin is evaluated for antitumor efficacy in patients with pancreatic cancer. It has an inhibitory activity on mitochondrial complex I .Therefore, plasma... 
SPRAGUE-DAWLEY RATS | NUTRIENT DEPRIVATION | CELLS | THERAPY | METABOLISM | PATHWAY | TOLERANCE | GLUCOSE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | STARVATION | Area Under Curve | Lactic Acid - blood | Gluconeogenesis - drug effects | Humans | Carcinoma, Adenosquamous - drug therapy | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Liver - physiopathology | Furans - therapeutic use | Lignans - therapeutic use | Oxidative Phosphorylation - drug effects | Pancreatic Neoplasms - drug therapy | Furans - pharmacokinetics | Arctium - chemistry | Antineoplastic Agents, Phytogenic - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacokinetics | Drugs, Chinese Herbal - therapeutic use | Kidney - physiopathology | Pancreatic Neoplasms - blood | Kaplan-Meier Estimate | Biomarkers - blood | Mitochondria - drug effects | Carcinoma, Adenosquamous - blood | Carcinoma, Pancreatic Ductal - blood | Carcinoma, Pancreatic Ductal - drug therapy | Drugs, Chinese Herbal - pharmacokinetics | Lignans - pharmacokinetics | Cell Line, Tumor | Plant Extracts - therapeutic use | Deoxycytidine - analogs & derivatives | Drug Screening Assays, Antitumor | Lactates | Development and progression | Care and treatment | Genetic aspects | Identification and classification | Pancreatic cancer | Plasma | Diabetic retinopathy | Gemcitabine | Liver | Clinical trials | Oncology | Colorimetry | Kinases | Cancer therapies | Anticancer properties | Electron transport chain | Mitochondria | Rodents | Surgery | Bioindicators | Pharmaceutical industry | NADH-ubiquinone oxidoreductase | Statistical analysis | Pharmacology | Metabolism | Patients | Chemotherapy | Biomarkers | Antitumor activity | Hypoxia | Lactic acid | Respiration | Alzheimers disease | Pharmacokinetics | Cancer
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2015, Volume 290, Issue 28, pp. 17495 - 17504
Journal Article
by Shay, Jerry W and Homma, Noriko and Zhou, Ruyun and Naseer, Muhammad Imran and Chaudhary, Adeel G and Al-Qahtani, Mohammed and Hirokawa, Nobutaka and Goudarzi, Maryam and Fornace, Albert J and Baeesa, Saleh and Hussain, Deema and Bangash, Mohammed and Alghamdi, Fahad and Schulten, Hans-Juergen and Carracedo, Angel and Khan, Ishaq and Qashqari, Hanadi and Madkhali, Nawal and Saka, Mohamad and Saini, Kulvinder S and Jamal, Awatif and Al-Maghrabi, Jaudah and Abuzenadah, Adel and Chaudhary, Adeel and Al Qahtani, Mohammed and Damanhouri, Ghazi and Alkhatabi, Heba and Goodeve, Anne and Crookes, Laura and Niksic, Nikolas and Beauchamp, Nicholas and Abuzenadah, Adel M and Vaught, Jim and Budowle, Bruce and Assidi, Mourad and Buhmeida, Abdelbaset and Merdad, Leena and Kumar, Sudhir and Miura, Sayaka and Gomez, Karen and Rasool, Mahmood and Rebai, Ahmed and Karim, Sajjad and Eldin, Hend F. Nour and Abusamra, Heba and Alhathli, Elham M and Salem, Nada and Al-Qahtani, Mohammed H and Faheem, Hossam and Agarwa, Ashok and Nieschlag, Eberhard and Wistuba, Joachim and Damm, Oliver S and Beg, Mohd A and Abdel-Meguid, Taha A and Mosli, Hisham A and Bajouh, Osama S and Coskun, Serdar and Abu-Elmagd, Muhammad and Dallol, Ashraf and Hakamy, Sahar and Al-Qahtani, Wejdan and Al-Harbi, Asia and Hussain, Shireen and Ozkosem, Burak and DuBois, Rick and Messaoudi, Safia S and Dandana, Maryam T and Mahjoub, Touhami and Almawi, Wassim Y and Abdalla, S and Al-Aama, M. Nabil and Elzawahry, Asmaa and Takahashi, Tsuyoshi and Mimaki, Sachiyo and Furukawa, Eisaku and Nakatsuka, Rie and Kurosaka, Isao and Nishigaki, Takahiko and Nakamura, Hiromi and Serada, Satoshi and Naka, Tetsuji and Hirota, Seiichi and Shibata, Tatsuhiro and Tsuchihara, Katsuya and Nishida, Toshirou and Kato, Mamoru and Mehmood, Sajid and Ashraf, Naeem Mahmood and Asif, Awais and Bilal, Muhammad and Mehmood, Malik Siddique and Hussain, Aadil and Jamal, Qazi Mohammad Sajid and Siddiqui, Mughees Uddin and Alzohairy, Mohammad A and Al Karaawi, Mohammad A and Nedjadi, Taoufik and Al-Khattabi, Heba and Al-Ammari, Adel and ...
BMC genomics, ISSN 1471-2164, 07/2016, Volume 17 Suppl 6, Issue S6, p. 487
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 625 - 9
Resistance to vandetanib, a type I RET kinase inhibitor, developed in a patient with metastatic lung adenocarcinoma harboring a CCDC6-RET fusion that initially... 
CELL LUNG-CANCER | MOLECULAR-DYNAMICS | PRECISION MEDICINE | FUSION | MODEL | MULTIDISCIPLINARY SCIENCES | Adenocarcinoma | Phenylalanine | Serine | Activation | Hydrophobicity | Drug resistance | Kinases | Metastases | Allosteric properties | Missense mutation | Lungs | Mutation | Crystal structure
Journal Article