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1. Full Text Microglial activation in normal-appearing brain regions of patients with cerebral glioma: a cross-sectional study
by Su, Zhangjie, Dr and Roncaroli, Federico, MD and Hinz, Rainer, PhD and Karabatsou, Konstantina, MD and Coope, David, PhD and Turkheimer, Federico, PhD and Jenkinson, Michael, PhD and Jackson, Alan, PhD and Herholz, Karl, MD and Gerhard, Alexander, MD
The Lancet (British edition), ISSN 0140-6736, 2017, Volume 389, pp. S92 - S92
Internal Medicine | Medicine, Experimental | Medical research | Pets | Brain | Gliomas | Brain tumors | Analysis | Epilepsy
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2. Full Text Reference and Target Region Modeling of [11C]-(R)-PK11195 Brain Studies
by Turkheimer, Federico E and Edison, Paul and Pavese, Nicola and Roncaroli, Federico and Anderson, Alexander N and Hammers, Alexander and Gerhard, Alexander and Hinz, Rainer and Tai, Yan F and Brooks, David J
The Journal of Nuclear Medicine, ISSN 0161-5505, 01/2007, Volume 48, Issue 1, pp. 158 - 167
Supervised clustering | PK11195 | PET | Microglia | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Humans | Carbon Radioisotopes - therapeutic use | Image Interpretation, Computer-Assisted | Antineoplastic Agents - therapeutic use | Models, Statistical | Positron-Emission Tomography - methods | Huntington Disease - radiotherapy | Case-Control Studies | Algorithms | Time Factors | Brain - pathology | Isoquinolines - therapeutic use | Kinetics | Pattern Recognition, Automated | Huntington Disease - drug therapy | Cluster Analysis | Cluster analysis | Studies | Plasma | Brain | Parameter estimation | Parkinsons disease | Nervous system | Pituitary gland | Models | Index Medicus
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3. Full Text [11C]-(R)PK11195 tracer kinetics in the brain of glioma patients and a comparison of two referencing approaches
by Su, Zhangjie and Herholz, Karl and Gerhard, Alexander and Roncaroli, Federico and Du Plessis, Daniel and Jackson, Alan and Turkheimer, Federico and Hinz, Rainer
European journal of nuclear medicine and molecular imaging, ISSN 1619-7070, 9/2013, Volume 40, Issue 9, pp. 1406 - 1419
Medicine & Public Health | Glioma | Orthopedics | Translocator protein | Oncology | Reference tissue | Kinetic analysis | Nuclear Medicine | Imaging / Radiology | Cardiology | [ 11 C]-( R )PK11195 | PET | C]-(R)PK11195 | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Radiopharmaceuticals - pharmacokinetics | Isoquinolines - pharmacokinetics | Receptors, GABA - genetics | Brain Neoplasms - diagnostic imaging | Brain Neoplasms - metabolism | Case-Control Studies | Glioma - metabolism | Tissue Distribution | Reference Standards | Glioma - diagnostic imaging | Amides - pharmacokinetics | Positron-Emission Tomography - standards | Receptors, GABA - metabolism | Protein Binding | Tracers (Biology) | Comparative analysis | Gliomas | Brain tumors | Brain | Kinetics | Patients | Cancer | Index Medicus | [11C]-(R)PK11195 | Original
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4. Full Text Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients
by Politis, Marios and Wu, Kit and Loane, Clare and Brooks, David J and Kiferle, Lorenzo and Turkheimer, Federico E and Bain, Peter and Molloy, Sophie and Piccini, Paola
The Journal of clinical investigation, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1340 - 1349
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Synapses - diagnostic imaging | Humans | Middle Aged | Serotonin 5-HT1 Receptor Agonists - pharmacology | Male | Parkinson Disease - drug therapy | Buspirone - pharmacology | Case-Control Studies | Serotonergic Neurons - metabolism | Antiparkinson Agents - therapeutic use | Synapses - metabolism | Dyskinesia, Drug-Induced - drug therapy | Female | Radiopharmaceuticals | Buspirone - therapeutic use | Dopamine - metabolism | Dyskinesia, Drug-Induced - etiology | Dyskinesia, Drug-Induced - diagnostic imaging | Raclopride | Parkinson Disease - diagnostic imaging | Double-Blind Method | Serotonergic Neurons - drug effects | Levodopa - therapeutic use | Putamen - diagnostic imaging | Treatment Outcome | Serotonin 5-HT1 Receptor Agonists - therapeutic use | Antiparkinson Agents - adverse effects | Levodopa - adverse effects | Radionuclide Imaging | Aged | Putamen - metabolism | Parkinson's disease | Serotonin | Physiological aspects | Development and progression | Properties | Identification and classification | Movement disorders | Studies | Values | Dopamine | Parkinsons disease | Index Medicus | Abridged Index Medicus
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5. Full Text Dopamine Synthesis Capacity Before Onset of Psychosis: A Prospective [(18)F]-DOPA PET Imaging Study
by Howes, Oliver D and Bose, Subrata K and Turkheimer, Federico and Valli, Isabel and Egerton, Alice and Valmaggia, Lucia R and Murray, Robin M and McGuire, Philip
The American journal of psychiatry, ISSN 0002-953X, 12/2011, Volume 168, Issue 12, pp. 1311 - 1317
Life Sciences & Biomedicine | Psychiatry | Science & Technology | Biological and medical sciences | Psychology. Psychoanalysis. Psychiatry | Medical sciences | Psychopathology. Psychiatry | Psychotic Disorders - diagnosis | Brain - diagnostic imaging | Prospective Studies | Humans | Dopamine - biosynthesis | Male | Positron-Emission Tomography | Corpus Striatum - metabolism | Brain - metabolism | Psychotic Disorders - metabolism | Psychotic Disorders - diagnostic imaging | Adult | Female | Corpus Striatum - diagnostic imaging | Dopamine | Neuropsychology | Mental disorders | Clinical outcomes | Index Medicus | Abridged Index Medicus
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6. Full Text Inflammation after trauma: Microglial activation and traumatic brain injury
by Ramlackhansingh, Anil F and Brooks, David J and Greenwood, Richard J and Bose, Subrata K and Turkheimer, Federico E and Kinnunen, Kirsi M and Gentleman, Steve and Heckemann, Rolf A and Gunanayagam, Karen and Gelosa, Giorgio and Sharp, David J
Annals of neurology, ISSN 0364-5134, 09/2011, Volume 70, Issue 3, pp. 374 - 383
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Injuries of the nervous system and the skull. Diseases due to physical agents | Neurology | Biological and medical sciences | Medical sciences | Traumas. Diseases due to physical agents | Wechsler Scales | Inflammation - pathology | Isoquinolines | Humans | Middle Aged | Male | Educational Status | Positron-Emission Tomography | Thalamus - pathology | Glasgow Coma Scale | Microglia - pathology | Adult | Female | Brain Injuries - psychology | Executive Function | Cognition Disorders - pathology | Amnesia - etiology | Diffusion Tensor Imaging | Macrophage Activation | Neuropsychological Tests | Magnetic Resonance Imaging | Image Processing, Computer-Assisted | Brain Injuries - pathology | Cluster Analysis | Memory - physiology | Medical research | Brain damage | Index Medicus
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7. Full Text Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [11C]PBR28 PET Brain Imaging Study
by Bloomfield, Peter S and Selvaraj, Sudhakar and Veronese, Mattia and Rizzo, Gaia and Bertoldo, Alessandra and Owen, David R and Bloomfield, Michael A.P and Bonoldi, Ilaria and Kalk, Nicola and Turkheimer, Federico and McGuire, Philip and de Paola, Vincenzo and Howes, Oliver D
The American journal of psychiatry, ISSN 0002-953X, 01/2016, Volume 173, Issue 1, pp. 44 - 52
Life Sciences & Biomedicine | Psychiatry | Science & Technology | Microglia - metabolism | Psychotic Disorders - diagnosis | Risk Assessment - methods | Reproducibility of Results | Schizophrenia - metabolism | Genetic Testing | Prognosis | Receptors, GABA - genetics | Humans | Male | Brain Mapping - methods | Positron-Emission Tomography - methods | Schizophrenia - etiology | Psychotic Disorders - metabolism | Psychotic Disorders - physiopathology | Schizophrenia - diagnosis | Schizophrenia - physiopathology | Gray Matter - metabolism | Gray Matter - physiopathology | Gray Matter - pathology | Microglia - pathology | Adult | Female | Neuroimmunomodulation | Psychosis | Brain | Medical imaging | Schizophrenia | Ligands | Risk factors | Polymorphism | Index Medicus | Abridged Index Medicus
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8. Full Text Kinetic Modeling without Accounting for the Vascular Component Impairs the Quantification of [11C]PBR28 Brain PET Data
by Rizzo, Gaia and Veronese, Mattia and Tonietto, Matteo and Zanotti-Fregonara, Paolo and Turkheimer, Federico E and Bertoldo, Alessandra
Journal of cerebral blood flow and metabolism, ISSN 0271-678X, 6/2014, Volume 34, Issue 6, pp. 1060 - 1069
TSPO | neuroinflammation | PK11195 | microglia | kinetic modeling | Endocrinology & Metabolism | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Hematology | Science & Technology | Acetamides - pharmacokinetics | Cerebrovascular Circulation - physiology | Cerebrovascular Circulation - drug effects | Models, Cardiovascular | Receptors, GABA - biosynthesis | Humans | Pyridines - pharmacokinetics | Acetamides - pharmacology | Positron-Emission Tomography | RNA, Messenger - biosynthesis | Carbon Isotopes - pharmacokinetics | Carbon Isotopes - pharmacology | Nerve Tissue Proteins - biosynthesis | Pyridines - pharmacology | Kinetics | Index Medicus | [11C]PBR28 | Original
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9. Full Text Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors
by Bhattacharyya, Sagnik and Egerton, Alice and Kim, Euitae and Rosso, Lula and Riano Barros, Daniela and Hammers, Alexander and Brammer, Michael and Turkheimer, Federico E and Howes, Oliver D and McGuire, Philip
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 15025 - 15
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Amygdala - diagnostic imaging | Amygdala - drug effects | Humans | Fear - drug effects | Male | Young Adult | Magnetic Resonance Imaging | Receptor, Cannabinoid, CB1 - agonists | Functional Neuroimaging | Anxiety - diagnostic imaging | Adult | Anxiety - chemically induced | Dronabinol - administration & dosage | Fear | Cannabis | Amygdala | Anxieties | Functional magnetic resonance imaging | Marijuana | Anxiety | Cannabinoid CB1 receptors | Acute effects | Tetrahydrocannabinol | Positron emission tomography | Index Medicus
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