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Nature, ISSN 0028-0836, 12/2017, Volume 552, Issue 7685, pp. 340 - 342
Journal Article
PLoS Biology, ISSN 1544-9173, 09/2018, Volume 16, Issue 9, pp. e2005046 - e2005046
The microenvironment of lymphoid organs can aid healthy immune function through provision of both structural and molecular support. In mice, fibroblastic... 
FIBROBLASTIC RETICULAR CELLS | GROWTH-FACTOR-BETA | HOMEOSTASIS | TGF-BETA | IMMUNOSUPPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDOLEAMINE 2,3-DIOXYGENASE | BIOLOGY | RECEPTORS | EXPRESSION | IMMUNE RESISTANCE | ANTIGEN | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2012, Volume 13, Issue 11, pp. 1118 - 1128
Journal Article
Molecular & cellular proteomics : MCP, ISSN 1535-9476, 07/2019, p. mcp.TIR119.001433
Receptors expressed on the plasma membrane and their interacting partners critically regulate cellular communication during homeostasis and disease, and as... 
Journal Article
Nature Immunology, ISSN 1529-2908, 09/2012, Volume 13, Issue 9, pp. 888 - 899
Journal Article
Seminars in immunology, 11/2017
Fibroblasts in secondary lymphoid organs, or fibroblastic reticular cells (FRC), are gate-keepers of immune responses. Here, we frame how these cells regulate... 
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7693, pp. 544 - 548
Therapeutic antibodies that block the programmed death-1 (PD-1)-programmed death-ligand 1 (PD-L1) pathway can induce robust and durable responses in patients... 
METASTATIC MELANOMA | CTLA-4 BLOCKADE | BLADDER-CANCER | THERAPY | LANDSCAPE | SUBTYPES | UROTHELIAL CARCINOMA | MULTIDISCIPLINARY SCIENCES | GENES | ADAPTIVE IMMUNE RESISTANCE | MPDL3280A | CD8-Positive T-Lymphocytes - cytology | Humans | Antibodies, Monoclonal - therapeutic use | Urothelium - pathology | Urologic Neoplasms - pathology | Neoplasm Metastasis | Urologic Neoplasms - drug therapy | Urologic Neoplasms - genetics | Immunotherapy | Antibodies - immunology | Antigens, Neoplasm - metabolism | Transforming Growth Factor beta - antagonists & inhibitors | Antigens, Neoplasm - analysis | Disease Models, Animal | Fibroblasts - metabolism | Antibodies - therapeutic use | Antigens, Neoplasm - immunology | Antibodies, Monoclonal - pharmacology | Treatment Outcome | B7-H1 Antigen - immunology | Urologic Neoplasms - immunology | Antibodies - pharmacology | Tumor Microenvironment - immunology | Collagen - metabolism | Phenotype | Animals | B7-H1 Antigen - antagonists & inhibitors | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | CD8-Positive T-Lymphocytes - drug effects | Urothelium - immunology | Mice | Mutation | CD8-Positive T-Lymphocytes - immunology | Urothelium - drug effects | Transforming Growth Factor beta - metabolism | Cohort Studies | Drug Resistance, Neoplasm - drug effects | PD-1 protein | CD8 antigen | Transforming growth factor-a | Antibodies | Parenchyma | Lymphocytes T | Metastasis | Immunity | Metastases | Genotype & phenotype | Signal transduction | Lymphocytes | Cell cycle | Fibroblasts | Growth factors | Urothelial cancer | Phenotypes | Cytokines | Melanoma | Blocking | Gene expression | Patients | Generalized linear models | Signaling | Stromal cells | Medical prognosis | Collagen | PD-L1 protein | Ligands | Determinants | Infiltration | Cancer | Tumors | Apoptosis | Index Medicus | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7486, pp. 52 - 57
Recent clinical trials showed that targeting of inhibitory receptors on T cells induces durable responses in a subset of cancer patients, despite advanced... 
SURVIVAL | IMMUNE CELLS | MELANOMA | CD8+ T-CELLS | PROGNOSTIC-FACTORS | SUPPRESSORS | PHOSPHATASE | MULTIDISCIPLINARY SCIENCES | PROTEINS | CANCER | LYMPHOCYTES | CD8-Positive T-Lymphocytes - cytology | RNA, Small Interfering - genetics | Immunotherapy - methods | Cell Proliferation | Molecular Targeted Therapy | Gene Knockdown Techniques | CD4-Positive T-Lymphocytes - immunology | Melanoma, Experimental - immunology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Cytokines - immunology | Lymphocytes, Tumor-Infiltrating - cytology | Reproducibility of Results | Antigens, Neoplasm - immunology | Mice, Inbred C57BL | Cytokines - secretion | Protein Phosphatase 2 - genetics | Protein Phosphatase 2 - deficiency | Tumor Microenvironment - immunology | Animals | Apoptosis - immunology | CD8-Positive T-Lymphocytes - secretion | Protein Phosphatase 2 - metabolism | High-Throughput Nucleotide Sequencing | Lymphocytes, Tumor-Infiltrating - secretion | Mice | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Immune response | Gene targeting | Immunotherapy | Physiological aspects | Genetic research | Research | T cells | Tumors | Spleen | Genes | Melanoma | Cytotoxicity | T cell receptors | Infections | Kinases | Cell growth | Lymphocytes | Rodents | Medical prognosis | Immune system | Index Medicus
Journal Article
Cellular and Molecular Life Sciences (CMLS), ISSN 1420-682X, 04/2014, Volume 71, Issue 7, p. 1305
Ablation of tetraspanin protein TSPAN12 from human MDA-MB-231 cells significantly decreased primary tumor xenograft growth, while increasing tumor apoptosis.... 
Proteins | Ablation (Surgery) | Metastasis | Growth | Stem cells | Phylogenetics | Cell growth | Tumors
Journal Article
Nature, ISSN 0028-0836, 10/2014, Volume 514, Issue 7253, pp. 498 - 502
Journal Article