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by Alexandrov, Ludmil B and Nik-Zainal, Serena and Wedge, David C and Aparicio, Samuel A. J. R and Behjati, Sam and Biankin, Andrew V and Bignell, Graham R and Bolli, Niccolò and Borg, Ake and Børresen-Dale, Anne-Lise and Boyault, Sandrine and Burkhardt, Birgit and Butler, Adam P and Caldas, Carlos and Davies, Helen R and Desmedt, Christine and Eils, Roland and Eyfjörd, Jórunn Erla and Foekens, John A and Greaves, Mel and Hosoda, Fumie and Hutter, Barbara and Ilicic, Tomislav and Imbeaud, Sandrine and Imielinski, Marcin and Jäger, Natalie and Jones, David T. W and Jones, David and Knappskog, Stian and Kool, Marcel and Lakhani, Sunil R and López-Otín, Carlos and Martin, Sancha and Munshi, Nikhil C and Nakamura, Hiromi and Northcott, Paul A and Pajic, Marina and Papaemmanuil, Elli and Paradiso, Angelo and Pearson, John V and Puente, Xose S and Raine, Keiran and Ramakrishna, Manasa and Richardson, Andrea L and Richter, Julia and Rosenstiel, Philip and Schlesner, Matthias and Schumacher, Ton N and Span, Paul N and Teague, Jon W and Totoki, Yasushi and Tutt, Andrew N. J and Valdés-Mas, Rafael and van Buuren, Marit M and van ’t Veer, Laura and Vincent-Salomon, Anne and Waddell, Nicola and Yates, Lucy R and Zucman-Rossi, Jessica and Andrew Futreal, P and McDermott, Ultan and Lichter, Peter and Meyerson, Matthew and Grimmond, Sean M and Siebert, Reiner and Campo, Elías and Shibata, Tatsuhiro and Pfister, Stefan M and Campbell, Peter J and Stratton, Michael R and ICGC MMML-Seq Consortium and ICGC PedBrain and ICGC Breast Cancer Consortium and Australian Pancreatic Cancer Genome Initiative and ICGC Breast Canc Consortium and Australian Pancreatic Canc Genome
Nature (London), ISSN 1476-4687, 2013, Volume 500, Issue 7463, pp. 415 - 421
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 486, Issue 7403, pp. 400 - 404
Journal Article
The Journal of clinical investigation, ISSN 1558-8238, 2019, Volume 129, Issue 3, pp. 1211 - 1228
The cyclic GMP-AMP synthase/stimulator of IFN genes (cGAS/STING) pathway detects cytosolic DNA to activate innate immune responses. Poly(ADP-ribose) polymerase... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | REPAIR | THERAPY | IMMUNOTHERAPY | DNA-DAMAGE RESPONSE | PD-L1 EXPRESSION | MUTATIONAL LANDSCAPE | SENSITIVITY | BLOCKADE | LYMPHOCYTES | Endonucleases - deficiency | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Endonucleases - metabolism | Interferon-gamma - metabolism | Triple Negative Breast Neoplasms - drug therapy | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | BRCA1 Protein - metabolism | Triple Negative Breast Neoplasms - pathology | Female | Membrane Proteins - metabolism | Interferon-gamma - genetics | Nucleotidyltransferases - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | A549 Cells | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | B7-H1 Antigen - genetics | BRCA1 Protein - genetics | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | B7-H1 Antigen - metabolism | Triple Negative Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - metabolism | Nucleotidyltransferases - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Poly (ADP-Ribose) Polymerase-1 - genetics | Enzyme inhibitors | Cellular immunity | Dosage and administration | Genetic aspects | Research | Gene expression | Lung cancer, Non-small cell | Drug therapy | Chromatin | DNA damage | Lung cancer | Poly(ADP-ribose) | Genomes | Mitochondrial DNA | Cancer therapies | DNA repair | Defects | Metastases | Ovarian cancer | Ribose | Lymphocytes | Immunotherapy | Cyclic GMP | Cell cycle | Sensors | Deoxyribonucleic acid--DNA | Phenotypes | Immune response | AMP | BRCA1 protein | Immunomodulation | Tumor cells | Non-small cell lung carcinoma | Poly(ADP-ribose) polymerase | Breast cancer | Patients | Poly(ADP-ribose) Polymerase 1 | Chemotherapy | Medical prognosis | Micronuclei | PD-L1 protein | ERCC1 protein | Interferon | Mutation | Tumors
Journal Article
Journal Article
Journal Article
Cell (Cambridge), ISSN 0092-8674, 05/2012, Volume 149, Issue 5, pp. 979 - 993
Journal Article
by Nik-Zainal, Serena and Davies, Helen and Staaf, Johan and Ramakrishna, Manasa and Glodzik, Dominik and Zou, Xueqing and Martincorena, Inigo and Alexandrov, Ludmil B and Martin, Sancha and Wedge, David C and Van Loo, Peter and Ju, Young Seok and Smid, Marcel and Brinkman, Arie B and Morganella, Sandro and Aure, Miriam R and Lingjærde, Ole Christian and Langerød, Anita and Ringnér, Markus and Ahn, Sung-Min and Boyault, Sandrine and Brock, Jane E and Broeks, Annegien and Butler, Adam and Desmedt, Christine and Dirix, Luc and Dronov, Serge and Fatima, Aquila and Foekens, John A and Gerstung, Moritz and Hooijer, Gerrit K. J and Jang, Se Jin and Jones, David R and Kim, Hyung-Yong and King, Tari A and Krishnamurthy, Savitri and Lee, Hee Jin and Lee, Jeong-Yeon and Li, Yilong and McLaren, Stuart and Menzies, Andrew and Mustonen, Ville and O’Meara, Sarah and Pauporté, Iris and Pivot, Xavier and Purdie, Colin A and Raine, Keiran and Ramakrishnan, Kamna and Rodríguez-González, F. Germán and Romieu, Gilles and Sieuwerts, Anieta M and Simpson, Peter T and Shepherd, Rebecca and Stebbings, Lucy and Stefansson, Olafur A and Teague, Jon and Tommasi, Stefania and Treilleux, Isabelle and Van den Eynden, Gert G and Vermeulen, Peter and Vincent-Salomon, Anne and Yates, Lucy and Caldas, Carlos and Veer, Laura van’t and Tutt, Andrew and Knappskog, Stian and Tan, Benita Kiat Tee and Jonkers, Jos and Borg, Åke and Ueno, Naoto T and Sotiriou, Christos and Viari, Alain and Futreal, P. Andrew and Campbell, Peter J and Span, Paul N and Van Laere, Steven and Lakhani, Sunil R and Eyfjord, Jorunn E and Thompson, Alastair M and Birney, Ewan and Stunnenberg, Hendrik G and van de Vijver, Marc J and Martens, John W. M and Børresen-Dale, Anne-Lise and Richardson, Andrea L and Kong, Gu and Thomas, Gilles and Stratton, Michael R and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Nature (London), ISSN 1476-4687, 2016, Volume 534, Issue 7605, pp. 47 - 54
Journal Article