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Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 566 - 581.e9
Microglia play a pivotal role in the maintenance of brain homeostasis but lose homeostatic function during neurodegenerative disorders. We identified a... 
Alzheimer’s disease | multiple sclerosis | transcriptional regulation | neurodegeneration | TREM2 | APOE | amyotrophic lateral sclerosis | microglia | Alzheimer's disease | GENE-EXPRESSION SIGNATURE | ACTIVATION | MULTIPLE-SCLEROSIS | ALZHEIMERS-DISEASE | MOUSE MODEL | MACROPHAGE | MICE | IMMUNOLOGY | DEFICIENCY | APOLIPOPROTEIN-E | CELL-DEATH | Microglia - metabolism | Apolipoproteins E - deficiency | Membrane Glycoproteins - metabolism | Humans | Cerebral Cortex - pathology | Transcriptome | Apoptosis - genetics | Monocytes - metabolism | Gene Expression Profiling | Monocytes - immunology | Phagocytosis - genetics | Neurodegenerative Diseases - immunology | Apolipoproteins E - metabolism | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Microglia - immunology | Superoxide Dismutase-1 - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Neurons - metabolism | Disease Models, Animal | Gene Targeting | Plaque, Amyloid - pathology | Signal Transduction | Gene Expression Regulation | Phagocytosis - immunology | Immune Tolerance | Mice, Transgenic | Neurodegenerative Diseases - genetics | Neurodegenerative Diseases - metabolism | Mice, Knockout | Encephalomyelitis, Autoimmune, Experimental | Phenotype | Animals | Apoptosis - immunology | Apolipoproteins E - genetics | Alzheimer Disease - metabolism | Superoxide Dismutase-1 - genetics | Plaque, Amyloid - metabolism | Mice | Alzheimer Disease - genetics | Transforming Growth Factor beta - metabolism | Receptors, Immunologic - metabolism | Cluster Analysis | Nervous system diseases | Multiple sclerosis | Neurons | Analysis | Amyotrophic lateral sclerosis | Genetic aspects | Genetic transcription | Apolipoproteins | Brain | Animal models | Myeloid cells | Disease | Transcription | Neurodegenerative diseases | Genes | Homeostasis | Microglia | Neurological diseases | Proteins | Molecular modelling | Restoration | Neurodegeneration | Apolipoprotein E | Rodents | β-Amyloid | Plaques | Phagocytosis | Apoptosis
Journal Article
Nature Immunology, ISSN 1529-2908, 12/2015, Volume 16, Issue 12, pp. 1228 - 1234
The molecular mechanisms that link the sympathetic stress response and inflammation remain obscure. Here we found that the transcription factor Nr4a1 regulated... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | NGFI-B | PRAZOSIN TREATMENT | MULTIPLE-SCLEROSIS | CELL-DEVELOPMENT | GENE-EXPRESSION | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | BLOOD-BRAIN-BARRIER | LEWIS RAT | NUCLEAR RECEPTOR | Tyrosine 3-Monooxygenase - metabolism | Central Nervous System - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Norepinephrine - immunology | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Nuclear Receptor Subfamily 4, Group A, Member 1 - immunology | Sympathetic Nervous System - immunology | Sympathetic Nervous System - metabolism | Central Nervous System - immunology | Inflammation - metabolism | Tyrosine 3-Monooxygenase - immunology | Myeloid Cells - immunology | Gene Expression - immunology | Encephalomyelitis, Autoimmune, Experimental - genetics | Macrophages - immunology | Disease Models, Animal | Cell Line | Rabbits | Nuclear Receptor Subfamily 4, Group A, Member 1 - genetics | Mice, Inbred C57BL | Cells, Cultured | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microscopy, Confocal | Tyrosine 3-Monooxygenase - genetics | Macrophages - metabolism | Animals | Norepinephrine - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Myeloid Cells - metabolism | Nuclear Receptor Subfamily 4, Group A, Member 1 - metabolism | Transcription factors | Immune response | Encephalomyelitis | Development and progression | Genetic aspects | Properties | Macrophages | Noradrenaline | Tyrosine | Physiological aspects | Multiple sclerosis
Journal Article
by Adlam, David and Olson, Timothy M and Combaret, Nicolas and Kovacic, Jason C and Iismaa, Siiri E and Al-Hussaini, Abtehale and O'Byrne, Megan M and Bouajila, Sara and Georges, Adrien and Mishra, Ketan and Braund, Peter S and d’Escamard, Valentina and Huang, Siying and Margaritis, Marios and Nelson, Christopher P and de Andrade, Mariza and Kadian-Dodov, Daniella and Welch, Catherine A and Mazurkiewicz, Stephani and Jeunemaitre, Xavier and Motreff, Pascal and Belle, Loïc and Dupouy, Patrick and Barnay, Pierre and Meneveau, Nicolas and Gilard, Martine and Rioufol, Gilles and Range, Grégoire and Brunel, Philippe and Delarche, Nicolas and Filippi, Emmanuelle and Le Bivic, Louis and Harbaoui, Brahim and Benamer, Hakim and Cayla, Guillaume and Varenne, Olivier and Manzo-Silberman, Stephane Peggy and Silvain, Johanne and Spaulding, Christian and Caussin, Christophe and Gerbaud, Edouard and Valy, Yann and Koning, René and Lhermusier, Thibault and Champin, Stanislas and Salengro, Emmanuel and Fluttaz, Arnaud and Zabalawi, Amer and Cottin, Yves and Teiger, Emmanuel and Saint-Etienne, Christophe and Ducrocq, Grégory and Marliere, Stéphanie and Boiffard, Emmanuel and Aubry, Pierre and Georges, Jean Louis and Bresson, Didier and De Poli, Fabien and Karrillon, Gaëtan and Roule, Vincent and Bali, Laurent and Valla, Mathieu and Gerbay, Antoine and Houpe, David and Dubreuil, Olivier and Monnier, Arsène and Mayaud, Norbert and Manchuelle, Aurélie and Commeau, Philippe and Bedossa, Marc and Wong, Claire Mei Yi and Giannoulatou, Eleni and Sweeting, Michael and Muller, David and Wood, Alice and McGrath-Cadell, Lucy and Fatkin, Diane and Dunwoodie, Sally L and Harvey, Richard and Holloway, Cameron and Empana, Jean-Philippe and Jouven, Xavier and Nikpay, Majid and Goel, Anuj and Won, Hong-Hee and Hall, Leanne M and Willenborg, Christina and Kanoni, Stavroula and Saleheen, Danish and Kyriakou, Theodosios and Nelson, Christopher P and Hopewell, Jemma C and Webb, Thomas R and Zeng, Lingyao and Dehghan, Abbas and Alver, Maris and Armasu, Sebastian M and Auro, Kirsi and Bjonnes, Andrew and Chasman, Daniel I and ... and CARDIoGRAMPlusC4D Study Group and DISCO Consortium and CARDIoGRAMPlusC4D Study Grp
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2019, Volume 73, Issue 1, pp. 58 - 66
Journal Article
Nature immunology, ISSN 1529-2908, 12/2015, Volume 16, Issue 12, pp. 1228 - 1234
Molecular mechanisms linking the sympathetic stress response and inflammation remain enigmatic. Here we demonstrate that the transcription factor Nr4a1... 
Journal Article
by Admon, Lindsay and Winkelman, Tyler and Moniz, Michelle and Davis, Matthew and Heisler, Michele and Dalton, Vanessa and Ake-Uzoigwe, Rukeme and Sanusi, Adedeji and Alonge, Olanike and Akinnawonu, Felix and Zhang, Dongping and Andres, Marc and Adri, Vicha Annisa and Edwards, Maureen P and Appel, Hoa and Cook, Kim and Archangelo, Silvania de Cassia Vieira and Archangelo, Silvania de Cassia Vieira and Ribeiro, Luis Paulo Barbosa and Kaman, Maisa and Maia, Rafaela Lemos Martins and Campos, Fabiola and Campos, Fabiola and Campos, Fabiola and Archangelo, Ivanildo and Archangelo, Ivanildo and Archangelo, Ivanildo and Veiga, Daniela Francescato and Barbosa, Lyliana Coutinho Resende and Ferreira, Lydia Masako and Novo, Neil Ferreira and Schnaider, Taylor Brandão and Armstrong, Mary Anne and Tucker, Lue-Yen and Young-Wolff, Kelly and Conway, Amy and Goler, Nancy and MacArthur, Taleen and Khanuja, Kavish and Bachmann, Gloria and Barbosa, Lyliana Coutinho Resende and Ribeiro, Márcio and Ribeiro, Luis Paulo Barbosa and Napoleão, Bruno and Veiga, Daniela Francescato and Schnaider, Taylor and Bartha, Jose Luis and Martinez-Sanchez, Nuria and Marin-Camacho, Silvia and Hueso-Zalvide, Edurne and Bataineh, Mohammad and Siani, Sheetal and Chiu, Sandy and Abbott, Paul and Steffen, Mark and Simmons, Jeffrey and Gopal, Vipin and Belton, Allyson and Holden, Kisha and Swahn, Monica and Hall, Stephanie and Bodnar-Deren, Susan and Legare, Katherine and Balbierez, Amy and Howell, Elizabeth A and Brosnan, Phoebe and Chowdhury, Nadia and Graham, Jacob and Yen, Miao-Shan and Cobb, Caroline and Brown, Amy and Casey, Frances and Bublitz, Margaret and Livingston, Zoe and Firoz, Tabassum and Tong, Iris and Pearlstein, Teri and MacLean, Joanna and Bourjeily, Ghada and Miller, Margaret and Bublitz, Margaret and Bourjeily, Ghada and Bilodeau, Courtney and Stroud, Laura and Bugg, Kimarie and Edwards, Roger and Burnham, Laura and Serano, Andrea and Merewood, Anne and Francisco, Antonio Marcos C and Francisco, Antonio Marcos C and de Lima, Rodrigo Pedro F and Juliano, Yara and Juliano, Yara and Ferreira, Lydia Masako and Veiga, Daniela Francescato and Veiga, Daniela Francescato and Veiga, Daniela Francescato and Archangelo, Silvania de Cassia Vieira and Carney, Patricia and ...
Journal of Women's Health, ISSN 1540-9996, 04/2017, Volume 26, Issue 4, pp. A-1 - A-57
Journal Article
CIRCULATION-GENOMIC AND PRECISION MEDICINE, ISSN 2574-8300, 04/2019, Volume 12, Issue 4, p. e002437
BACKGROUND: Spontaneous coronary artery dissection (SCAD) is an uncommon idiopathic disorder predominantly affecting young, otherwise healthy women. Rare... 
coronary artery disease | integrins | DOMAIN | CARDIAC & CARDIOVASCULAR SYSTEMS | genetics | talin | DNA | GENETICS & HEREDITY | cohort studies | IBS2 | BINDING-SITES | humans
Journal Article
Monographs of the Western North American Naturalist, ISSN 1545-0228, 2014, Volume 7, Issue 1, pp. 68 - 81
Paleontological resource inventories for the parks of the National Park Service's Mediterranean Coast Inventory and Monitoring Network (MEDN) indicate a... 
National parks | Natural resources | Geology | Recreation | Fauna | Volcanology | Geological resources | Rocks | Paleontology | Fossils | Coasts | Islands
Journal Article
01/2016, ISBN 9781369615708
California’s recent drought has brought economic hardship and attention to long-standing weaknesses in California’s water management. One weakness is... 
Water Resource Management | Operations research | Civil engineering
Dissertation
01/2003, ISBN 9780493968940
In older, industrialized countries (OICs) such as the U.S., since 1973 and sometimes earlier, community leaders have been confronted by significant economic... 
Sociology
Dissertation
National Post, ISSN 1486-8008, 12/2007
[Charles Krauthammer] has made some very valid points about the separation of church and state. However his citing Europe as a great example of an "open,... 
Newspaper Article
National Post, ISSN 1486-8008, 11/2004
What planet is Ms. [Sheila Copps] on? Didn't she see that Republicans took control of the White House, Senate and Congress? That is called a landslide victory. 
Newspaper Article
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