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humans (20) 20
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prostatic neoplasms - genetics (19) 19
life sciences & biomedicine (18) 18
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1. Full Text Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer
by Elena Castro and Chee Goh and David Olmos and Ed Saunders and Daniel Leongamornlert and Malgorzata Tymrakiewicz and Nadiya Mahmud and Tokhir Dadaev and Koveela Govindasami and Michelle Guy and Emma Sawyer and Rosemary Wilkinson and Audrey Ardern-Jones and Steve Ellis and Debra Frost and Susan Peock and D. Gareth Evans and Marc Tischkowitz and Trevor Cole and Rosemarie Davidson and Diana Eccles and Carole Brewer and Fiona Douglas and Mary E. Porteous and Alan Donaldson and Huw Dorkins and Louise Izatt and Jackie Cook and Shirley Hodgson and M. John Kennedy and Lucy E. Side and Jacqueline Eason and Alex Murray and Antonis C. Antoniou and Douglas F. Easton and Zsofia Kote-Jarai and Rosalind Eeles
Journal of clinical oncology, ISSN 0732-183X, 05/2013, Volume 31, Issue 14, pp. 1748 - 1757
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Predictive Value of Tests | Lymph Nodes - pathology | Prognosis | Follow-Up Studies | Humans | Middle Aged | Male | Prostatic Neoplasms - therapy | Neoplasm Grading | Prostatic Neoplasms - genetics | Antineoplastic Agents, Hormonal - therapeutic use | Nomograms | Aged, 80 and over | Germ-Line Mutation | Adult | Brachytherapy | Retrospective Studies | Radiotherapy, Adjuvant | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Lymphatic Metastasis | Prostatic Neoplasms - mortality | BRCA1 Protein - genetics | Phenotype | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Heterozygote | Prostatectomy | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Palliative Care - methods | Index Medicus | Dxst3 | Original Reports | Guc54 | Guc49
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2. Full Text Multiple newly identified loci associated with prostate cancer susceptibility
by Eeles, Rosalind A and Kote-Jarai, Zsofia and Giles, Graham G and Olama, Ali Amin Al and Guy, Michelle and Jugurnauth, Sarah K and Mulholland, Shani and Leongamornlert, Daniel A and Edwards, Stephen M and Morrison, Jonathan and Field, Helen I and Southey, Melissa C and Severi, Gianluca and Donovan, Jenny L and Hamdy, Freddie C and Dearnaley, David P and Muir, Kenneth R and Smith, Charmaine and Bagnato, Melisa and Ardern-Jones, Audrey T and Hall, Amanda L and O'Brien, Lynne T and Gehr-Swain, Beatrice N and Wilkinson, Rosemary A and Cox, Angie and Lewis, Sarah and Brown, Paul M and Jhavar, Sameer G and Tymrakiewicz, Malgorzata and Lophatananon, Artitaya and Bryant, Sarah L and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Fisher, Cyril and Jamieson, Charles and Cooper, Colin S and English, Dallas R and Hopper, John L and Neal, David E and Easton, Douglas F and British Assoc Urological Surg Sect and Uk Genetic Prostate Canc Study Col and Uk ProtecT Study Collaborators and UK Genetic Prostate Cancer Study Collaborators and UK ProtecT Study Collaborators and British Association of Urological Surgeons' Section of Oncology and The UK Genetic Prostate Cancer Study Collaborators and The UK ProtecT Study Collaborators
Nature genetics, ISSN 1061-4036, 03/2008, Volume 40, Issue 3, pp. 316 - 321
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Nephrology. Urinary tract diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Male genital diseases | Tumors | Genetic Predisposition to Disease | Humans | Middle Aged | Genotype | Male | United Kingdom | Chromosome Mapping | Case-Control Studies | Algorithms | Prostatic Neoplasms - genetics | Aged, 80 and over | Adult | Aged | Polymorphism, Single Nucleotide | Australia | Quantitative Trait Loci | Prostate-specific antigen | Physiological aspects | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Prostate cancer | Health aspects | Risk factors | Genetic markers | Chromosomes | Genomics | Single-nucleotide polymorphism | DNA | Blood | chromosome 3 | Index Medicus
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3. Full Text Multiple loci on 8q24 associated with prostate cancer susceptibility
by Al Olama, Ali Amin and Kote-Jarai, Zsofia and Giles, Graham G and Guy, Michelle and Morrison, Jonathan and Severi, Gianluca and Leongamornlert, Daniel A and Tymrakiewicz, Malgorzata and Jhavar, Sameer and Saunders, Ed and Hopper, John L and Southey, Melissa C and Muir, Kenneth R and English, Dallas R and Dearnaley, David P and Ardern-Jones, Audrey T and Hall, Amanda L and O'Brien, Lynne T and Wilkinson, Rosemary A and Sawyer, Emma and Lophatananon, Artitaya and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Cooper, Colin and Donovan, Jenny L and Hamdy, Freddie C and Neal, David E and Eeles, Rosalind A and Easton, Douglas F and UK Prostate Testing Canc Treatment and British Assoc Urol Surg Section On and UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology
Nature genetics, ISSN 1061-4036, 10/2009, Volume 41, Issue 10, pp. 1058 - 1060
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Nephrology. Urinary tract diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Male genital diseases | Methods, theories and miscellaneous | Tumors | Genome-Wide Association Study | Disease Susceptibility | Prostatic Neoplasms - genetics | Humans | Risk Factors | Genotype | Male | Chromosomes, Human, Pair 8 | Polymorphism, Single Nucleotide | Genome, Human | Quantitative trait loci | Care and treatment | Disease susceptibility | Genetic aspects | Research | Diagnosis | Single nucleotide polymorphisms | Health aspects | Prostate cancer | Identification and classification | Risk factors | Genetics | Regression analysis | Binding sites | Colorectal cancer | Index Medicus
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4. Full Text Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
by Eeles, R.A and Kote Jarai, Z and Al Olama, A.A and Giles, G.G and Guy, M and Severi, G and Muir, K and Hopper, J.L and Henderson, B.E and Haiman, C.A and Schleutker, J and Hamdy, F.C and Neal, D.E and Donovan, J.L and Stanford, J.L and Ostrander, E.A and Ingles, S.A and John, E.M and Thibodeau, S.N and Schaid, D and Park, J.Y and Spurdle, A and Clements, J and Dickinson, J.L and Maier, C and Vogel, W and Dork, T and Rebbeck, T.R and Cooney, K.A and Cannon Albright, L and Chappuis, P.O and Hutter, P and Zeegers, M and Kaneva, R and Zhang, H.W and Lu, Y.J and Foulkes, WD and English, D.R and Leongamornlert, D.A and Tymrakiewicz, M and Morrison, J and Ardern Jones, A.T and Hall, A.L and O'Brien, L.T and Wilkinson, R.A and Saunders, E.J and Page, E.C and Sawyer, E.J and Edwards, S.M and Dearnaley, D.P and Horwich, A and Huddart, R.A and Khoo, V.S and Parker, C.C and Van As, N and Woodhouse, C.J and Thompson, A and Christmas, T and Ogden, C and Cooper, C.S and Southey, M.C and Lophatananon, A and Liu, J.F and Kolonel, L.N and Le Marchand, L and Wahlfors, T and Tammela, T.L and Auvinen, A and Lewis, S.J and Cox, A and FitzGerald, L.M and Koopmeiners, J.S and Karyadi, D.M and Kwon, E.M and Stern, M.C and Corral, R and Joshi, A.D and Shahabi, A and McDonnell, S.K and Sellers, T.A and Pow Sang, J and Chambers, S and Aitken, J and Gardiner, R.A and Batra, J and Kedda, M.A and Lose, F and Polanowski, A and Patterson, B and Serth, J and Meyer, A and Luedeke, M and Stefflova, K and Ray, A.M and Lange, E.M and Farnham, J and Khan, H and Slavov, C and Mitkova, A and British Assoc Urological Surg and PRACTICAL Consortium and UK ProtecT Study Collaborators and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The PRACTICAL Consortium and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators
Nature genetics, ISSN 1061-4036, 01/2009, Volume 41, Issue 10, pp. 1116 - 21
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Nephrology. Urinary tract diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Male genital diseases | Tumors | Genome-Wide Association Study | Disease Susceptibility | Prostatic Neoplasms - genetics | Humans | Genotype | Male | Chromosomes, Human | Polymorphism, Single Nucleotide | Genome, Human | Disease susceptibility | Genetic aspects | Research | Diagnosis | Single nucleotide polymorphisms | Health aspects | Prostate cancer | Risk factors | Studies | Medical research | Inflation | Regression analysis | Chromosomes | Index Medicus
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5. Full Text Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer
by Castro, Elena and Goh, Chee and Leongamornlert, Daniel and Saunders, Ed and Tymrakiewicz, Malgorzata and Dadaev, Tokhir and Govindasami, Koveela and Guy, Michelle and Ellis, Steve and Frost, Debra and Bancroft, Elizabeth and Cole, Trevor and Tischkowitz, Marc and Kennedy, M. John and Eason, Jacqueline and Brewer, Carole and Evans, D. Gareth and Davidson, Rosemarie and Eccles, Diana and Porteous, Mary E and Douglas, Fiona and Adlard, Julian and Donaldson, Alan and Antoniou, Antonis C and Kote-Jarai, Zsofia and Easton, Douglas F and Olmos, David and Eeles, Rosalind
European urology, ISSN 0302-2838, 2014, Volume 68, Issue 2, pp. 186 - 193
Urology | Prognostic factor | Prostatectomy | BRCA1 | BRCA2 | Homologous repair | Radiotherapy | Prostate cancer | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Multivariate Analysis | Humans | Middle Aged | Male | Prostatic Neoplasms - therapy | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Time Factors | DNA Mutational Analysis | Germ-Line Mutation | Prostatic Neoplasms - blood | Kallikreins - blood | Retrospective Studies | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | United Kingdom | Prostatectomy - adverse effects | Prostate-Specific Antigen - blood | Prostatic Neoplasms - mortality | BRCA1 Protein - genetics | Disease-Free Survival | Phenotype | Prostatectomy - mortality | BRCA2 Protein - genetics | Index Medicus
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6. Full Text Multiple Novel Prostate Cancer Predisposition Loci Confirmed by an International Study: The PRACTICAL Consortium
by Zsofia Kote-Jarai and Douglas F. Easton and Janet L. Stanford and Elaine A. Ostrander and Johanna Schleutker and Sue A. Ingles and Daniel Schaid and Stephen Thibodeau and Thilo Dörk and David Neal and Angela Cox and Christiane Maier and Walter Vogel and Michelle Guy and Kenneth Muir and Artitaya Lophatananon and Mary-Anne Kedda and Amanda Spurdle and Suzanne Steginga and Esther M. John and Graham Giles and John Hopper and Pierre O. Chappuis and Pierre Hutter and William D. Foulkes and Nancy Hamel and Claudia A. Salinas and Joseph S. Koopmeiners and Danielle M. Karyadi and Bo Johanneson and Tiina Wahlfors and Teuvo L. Tammela and Mariana C. Stern and Roman Corral and Shannon K. McDonnell and Peter Schürmann and Andreas Meyer and Rainer Kuefer and Daniel A. Leongamornlert and Malgorzata Tymrakiewicz and Jo-fen Liu and Tracy O'Mara and R.A. (Frank) Gardiner and Joanne Aitken and Amit D. Joshi and Gianluca Severi and Dallas R. English and Melissa Southey and Stephen M. Edwards and Ali Amin Al Olama and Rosalind A. Eeles and PRACTICAL Consortium and The PRACTICAL Consortium
Cancer epidemiology, biomarkers & prevention, ISSN 1055-9965, 08/2008, Volume 17, Issue 8, pp. 2052 - 2061
SNPs | Consortium | Relative risks | susceptibility loci | Prostate cancer | Oncology | Public, Environmental & Occupational Health | Life Sciences & Biomedicine | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Tumors | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Humans | Genotype | Logistic Models | Male | Risk | Precancerous Conditions - genetics | Case-Control Studies | Genetic Variation | Prostate - pathology | Prostatic Neoplasms - genetics | Alleles | Precancerous Conditions - pathology | Polymorphism, Single Nucleotide | Index Medicus
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7. Full Text Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort
by Goh, Chee L and Saunders, Edward J and Leongamornlert, Daniel A and Tymrakiewicz, Malgorzata and Thomas, Karen and Selvadurai, Elizabeth D and Woode‐Amissah, Ruth and Dadaev, Tokhir and Mahmud, Nadiya and Castro, Elena and Olmos, David and Guy, Michelle and Govindasami, Koveela and O'Brien, Lynne T and Hall, Amanda L and Wilkinson, Rosemary A and Sawyer, Emma J and Al Olama, Ali Amin and Easton, Douglas F and Kote‐Jarai, Zsofia and Parker, Chris C and Eeles, Rosalind A
BJU international, ISSN 1464-4096, 09/2013, Volume 112, Issue 5, pp. 666 - 673
genetic risk profiles | prostate cancer | family history | active surveillance | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Male genital diseases | Tumors | Genetic Predisposition to Disease | Genome-Wide Association Study | Prognosis | Risk Assessment | Humans | Middle Aged | Genotype | Male | Prostatic Neoplasms - epidemiology | Prostatic Neoplasms - genetics | Family | Aged | Polymorphism, Single Nucleotide | Retrospective Studies | United Kingdom - epidemiology | Sentinel Surveillance | Genetic aspects | Prostate cancer | Health aspects | Risk factors | Genomes | Histology | Family medical history | Index Medicus
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8. Full Text Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression
by Kote-Jarai, Zsofia and Saunders, Edward and Leongamornlert, Daniel A and Tymrakiewicz, Malgorzata and Dadaev, Tokhir and Jugurn-Little, Sarah and Ross-Adams, Helen and Al Olama, Ali Amin and Benlloch, Sara and Halim, Silvia and Russel, Roslin and Dunning, Alison M and Luccarini, Craig and Dennis, Joe and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Muir, Ken and Giles, Graham G and Severi, Gianluca and Wiklund, Fredrik and Gronberg, Henrik and Haiman, Christopher A and Schumacher, Fredrick and Henderson, Brian E and Marchand, Loic Le and Lindstrom, Sara and Kraft, Peter and Hunter, David J and Gapstur, Susan and Chanock, Stephen and Berndt, Sonja I and Albanes, Demetrius and Andriole, Gerald and Schleutker, Johanna and Weischer, Maren and Canzian, Federico and Riboli, Elio and Key, Tim J and Travis, Ruth C and Campa, Daniele and Ingles, Sue A and John, Esther and Hayes, Richard B and Pharoah, Paul and Khaw, Kay-Tee and Stanford, Janet L and Ostrander, Elaine A and Signorello, Lisa B and Thibodeau, Stephen N and Schaid, Dan and Maier, Christiane and Vogel, Walther and Kibel, Adam S and Cybulski, Cezary and Lubinski, Jan and Cannon-Albright, Lisa and Brenner, Hermann and Park, Jong Y and Kaneva, Radka and Batra, Jyotsna and Spurdle, Amanda and Clements, Judith A and Teixeira, Manuel R and Govindasami, Koveela and Guy, Michelle and Wilkinson, Rosemary A and Sawyer, Emma J and Morgan, Angela and Dicks, Ed and Baynes, Caroline and Conroy, Don and Bojesen, Stig E and Kaaks, Rudolf and Vincent, Daniel and Bacot, Francois and Tessier, Daniel C and Easton, Douglas F and Eeles, Rosalind A and UK ProtecT Study Collaborators and COGS-CRUK GWAS-ELLIPSE Part and UK Genetic Prostate Canc and PRACTICAL Consortium and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative
Human molecular genetics, ISSN 0964-6906, 2013, Volume 22, Issue 12, pp. 2520 - 2528
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Promoter Regions, Genetic | Genetic Predisposition to Disease | Humans | Genotype | Male | Chromosome Mapping | Case-Control Studies | Linkage Disequilibrium | Prostatic Neoplasms - genetics | Telomerase - genetics | Prostatic Neoplasms - enzymology | Adult | Telomerase - metabolism | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 5 - genetics | Index Medicus | Association Studies | Medicin och hälsovetenskap
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9. Full Text A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease
by Al Olama, Ali Amin and Kote-Jarai, Zsofia and Schumacher, Fredrick R and Wiklund, Fredrik and Berndt, Sonja I and Benlloch, Sara and Giles, Graham G and Severi, Gianluca and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Hunter, David J and Henderson, Brian E and Thun, Michael J and Gaziano, Michael and Giovannucci, Edward L and Siddiq, Afshan and Travis, Ruth C and Cox, David G and Canzian, Federico and Riboli, Elio and Key, Timothy J and Andriole, Gerald and Albanes, Demetrius and Hayes, Richard B and Schleutker, Johanna and Auvinen, Anssi and Tammela, Teuvo L.J and Weischer, Maren and Stanford, Janet L and Ostrander, Elaine A and Cybulski, Cezary and Lubinski, Jan and Thibodeau, Stephen N and Schaid, Daniel J and Sorensen, Karina D and Batra, Jyotsna and Clements, Judith A and Chambers, Suzanne and Aitken, Joanne and Gardiner, Robert A and Maier, Christiane and Vogel, Walther and Dörk, Thilo and Brenner, Hermann and Habuchi, Tomonori and Ingles, Sue and John, Esther M and Dickinson, Joanne L and Cannon-Albright, Lisa and Teixeira, Manuel R and Kaneva, Radka and Zhang, Hong-Wei and Lu, Yong-Jie and Park, Jong Y and Cooney, Kathleen A and Muir, Kenneth R and Leongamornlert, Daniel A and Saunders, Edward and Tymrakiewicz, Malgorzata and Mahmud, Nadiya and Guy, Michelle and Govindasami, Koveela and O'Brien, Lynne T and Wilkinson, Rosemary A and Hall, Amanda L and Sawyer, Emma J and Dadaev, Tokhir and Morrison, Jonathan and Dearnaley, David P and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Van As, Nicholas and Woodhouse, Christopher J and Thompson, Alan and Dudderidge, Tim and Ogden, Chris and Cooper, Colin S and Lophatonanon, Artitaya and Southey, Melissa C and Hopper, John L and English, Dallas and Virtamo, Jarmo and Marchand, Loic Le and Campa, Daniele and Kaaks, Rudolf and Lindstrom, Sara and Diver, W. Ryan and Gapstur, Susan and Yeager, Meredith and Cox, Angela and Stern, Mariana C and Corral, Roman and Aly, Markus and Isaacs, William and Adolfsson, Jan and Xu, Jianfeng and Zheng, S. Lilly and ... and Uk ProtecT Study Collaborators and Australian Prostate Canc and British Assoc Urological Surg and PRACTICAL Consortium and UK ProtecT Study Collaborators and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and Australian Prostate Cancer Bioresource and The PRACTICAL Consortium and The Australian Prostate Cancer Bioresource and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators
Human molecular genetics, ISSN 0964-6906, 01/2013, Volume 22, Issue 2, pp. 408 - 415
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Prostatic Neoplasms - genetics | Humans | Male | Polymorphism, Single Nucleotide | Odds Ratio | Quantitative Trait Loci | Case-Control Studies | Disease Progression | chromosome 19 | Prognosis | Reviews | Genotyping | Susceptibility | Heritability | Single-nucleotide polymorphism | Prostate cancer | Index Medicus | Association Studies | Medicinsk genetik | Klinisk medicin | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cancer och onkologi
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