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1. Full Text Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer
by Elena Castro and Chee Goh and David Olmos and Ed Saunders and Daniel Leongamornlert and Malgorzata Tymrakiewicz and Nadiya Mahmud and Tokhir Dadaev and Koveela Govindasami and Michelle Guy and Emma Sawyer and Rosemary Wilkinson and Audrey Ardern-Jones and Steve Ellis and Debra Frost and Susan Peock and D. Gareth Evans and Marc Tischkowitz and Trevor Cole and Rosemarie Davidson and Diana Eccles and Carole Brewer and Fiona Douglas and Mary E. Porteous and Alan Donaldson and Huw Dorkins and Louise Izatt and Jackie Cook and Shirley Hodgson and M. John Kennedy and Lucy E. Side and Jacqueline Eason and Alex Murray and Antonis C. Antoniou and Douglas F. Easton and Zsofia Kote-Jarai and Rosalind Eeles
Journal of Clinical Oncology, ISSN 0732-183X, 05/2013, Volume 31, Issue 14, pp. 1748 - 1757
Purpose To analyze the baseline clinicopathologic characteristics of prostate tumors with germline BRCA1 and BRCA2 (BRCA1/2) mutations and the prognostic value... 
MORTALITY | RATES | RANDOMIZED PROSTATE | ONCOLOGY | INCREASE | MEN | RADICAL PROSTATECTOMY | CARRIERS | PROGRESSION | Predictive Value of Tests | Lymph Nodes - pathology | Prognosis | Follow-Up Studies | Humans | Middle Aged | Male | Prostatic Neoplasms - therapy | Neoplasm Grading | Prostatic Neoplasms - genetics | Antineoplastic Agents, Hormonal - therapeutic use | Nomograms | Aged, 80 and over | Germ-Line Mutation | Adult | Brachytherapy | Retrospective Studies | Radiotherapy, Adjuvant | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Lymphatic Metastasis | Prostatic Neoplasms - mortality | BRCA1 Protein - genetics | Phenotype | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Heterozygote | Prostatectomy | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Palliative Care - methods | Dxst3 | Original Reports | Guc54 | Guc49
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2. Full Text Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
by Eeles, Rosalind A and Olama, Ali Amin Al and Benlloch, Sara and Saunders, Edward J and Leongamornlert, Daniel A and Tymrakiewicz, Malgorzata and Ghoussaini, Maya and Luccarini, Craig and Dennis, Joe and Jugurnauth-Little, Sarah and Dadaev, Tokhir and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Muir, Ken and Giles, Graham G and Severi, Gianluca and Wiklund, Fredrik and Gronberg, Henrik and Haiman, Christopher A and Schumacher, Fredrick and Henderson, Brian E and Le Marchand, Loic and Lindstrom, Sara and Kraft, Peter and Hunter, David J and Gapstur, Susan and Chanock, Stephen J and Berndt, Sonja I and Albanes, Demetrius and Andriole, Gerald and Schleutker, Johanna and Weischer, Maren and Canzian, Federico and Riboli, Elio and Key, Tim J and Travis, Ruth C and Campa, Daniele and Ingles, Sue A and John, Esther M and Hayes, Richard B and Pharoah, Paul D. P and Pashayan, Nora and Khaw, Kay-Tee and Stanford, Janet L and Ostrander, Elaine A and Signorello, Lisa B and Thibodeau, Stephen N and Schaid, Dan and Maier, Christiane and Vogel, Walther and Kibel, Adam S and Cybulski, Cezary and Lubinski, Jan and Cannon-Albright, Lisa and Brenner, Hermann and Park, Jong Y and Kaneva, Radka and Batra, Jyotsna and Spurdle, Amanda B and Clements, Judith A and Teixeira, Manuel R and Dicks, Ed and Lee, Andrew and Dunning, Alison M and Baynes, Caroline and Conroy, Don and Maranian, Melanie J and Ahmed, Shahana and Govindasami, Koveela and Guy, Michelle and Wilkinson, Rosemary A and Sawyer, Emma J and Morgan, Angela and Dearnaley, David P and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Van As, Nicholas J and Woodhouse, Christopher J and Thompson, Alan and Dudderidge, Tim and Ogden, Chris and Cooper, Colin S and Lophatananon, Artitaya and Cox, Angela and Southey, Melissa C and Hopper, John L and English, Dallas R and Aly, Markus and Adolfsson, Jan and Xu, Jiangfeng and Zheng, Siqun L and Yeager, Meredith and Kaaks, Rudolf and Diver, W Ryan and Gaudet, Mia M and Stern, Mariana C and Corral, Roman and ... and UK Genetic Prostate Canc Study and Australian Prostate Canc and PRACTICAL Prostate Canc Assoc Grp and COGS-Canc Res UK GWAS-ELLIPSE Part and UK ProtecT Prostate Testing Canc and COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators and Australian Prostate Cancer Bioresource and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The Australian Prostate Cancer Bioresource and The UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators and The COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology
Nature Genetics, ISSN 1061-4036, 04/2013, Volume 45, Issue 4, pp. 385 - 391
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we... 
VARIANTS | PREDISPOSITION | MEN | GENETICS & HEREDITY | MUTATIONS | HOXB13 | GENOME-WIDE ASSOCIATION | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Oligonucleotide Array Sequence Analysis | Humans | Risk Factors | Genetic Loci - genetics | Prostatic Neoplasms - etiology | Cooperative Behavior | Genotype | Male | Case-Control Studies | Polymorphism, Single Nucleotide - genetics | Quantitative trait loci | Genetic susceptibility | Genetic aspects | Research | Prostate cancer | Identification and classification | Risk factors | Studies | Confidence intervals | Genotype & phenotype | Genealogy | Quality control | Cell cycle | Genomes | DNA repair | Deoxyribonucleic acid--DNA | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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3. Full Text A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
by Al Olama, Ali Amin and Kote-Jarai, Zsofia and Berndt, Sonja I and Conti, David V and Schumacher, Fredrick and Han, Ying and Benlloch, Sara and Hazelett, Dennis J and Wang, Zhaoming and Saunders, E and Leongamornlert, Daniel and Lindstrom, Sara and Jugurnauth-Little, Sara and Dadaev, Tokhir and Tymrakiewicz, Malgorzata and Stram, Daniel O and Rand, Kristin and Wan, Peggy and Stram, Alex and Sheng, Xin and Pooler, Loreall C and Park, Karen and Xia, Lucy and Tyrer, Jonathan and Kolonel, Laurence N and Le Marchand, Loic and Hoover, Robert N and Machiela, Mitchell J and Yeager, Merideth and Burdette, Laurie and Chung, Charles C and Hutchinson, Amy and Yu, Kai and Goh, Chee and Ahmed, Mahbubl and Govindasami, Koveela and Guy, Michelle and Tammela, Teuvo L J and Auvinen, Anssi and Wahlfors, Tiina and Schleutker, Johanna and Visakorpi, Tapio and Leinonen, Katri A and Xu, Jianfeng and Aly, Markus and Donovan, Jenny and Travis, Ruth C and Key, Tim J and Siddiq, Afshan and Canzian, Federico and Khaw, Kay-Tee and Takahashi, Atsushi and Kubo, Michiaki and Pharoah, Paul and Pashayan, Nora and Weischer, Maren and Nordestgaard, Borge G and Nielsen, Sune F and Klarskov, Peter and Røder, Martin Andreas and Iversen, Peter and Thibodeau, Stephen N and McDonnell, Shannon K and Schaid, Daniel J and Stanford, Janet L and Kolb, Suzanne and Holt, Sarah and Knudsen, Beatrice and Coll, Antonio Hurtado and Gapstur, Susan M and Diver, W Ryan and Stevens, Victoria L and Maier, Christiane and Luedeke, Manuel and Herkommer, Kathleen and Rinckleb, Antje E and Strom, Sara S and Pettaway, Curtis and Yeboah, Edward D and Tettey, Yao and Biritwum, Richard B and Adjei, Andrew A and Tay, Evelyn and Truelove, Ann and Niwa, Shelley and Chokkalingam, Anand P and Cannon-Albright, Lisa and Cybulski, Cezary and Wokołorczyk, Dominika and Kluźniak, Wojciech and Park, Jong and Sellers, Thomas and Lin, Hui-Yi and Isaacs, William B and Partin, Alan W and Brenner, Hermann and Dieffenbach, Aida Karina and Stegmaier, Christa and Chen, Constance and Giovannucci, Edward L and ... and Practical Prostate Canc Associatio and GAME-ON ELLIPSE Consortium and Breast Prostate Canc Cohort Consor and COGS Consortium and Breast and Prostate Cancer Cohort Consortium (BPC3) and GAME-ON/ELLIPSE Consortium and COGS (Collaborative Oncological Gene-environment Study) Consortium and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The Breast and Prostate Cancer Cohort Consortium (BPC3) and The COGS (Collaborative Oncological Gene-environment Study) Consortium and The GAME-ON/ELLIPSE Consortium
Nature Genetics, ISSN 1061-4036, 09/2014, Volume 46, Issue 10, pp. 1103 - 1109
Genome-wide association studies (GWAS) have identified 76 variants associated with prostate cancer risk predominantly in populations of European ancestry. To... 
COMMON VARIANTS | GLIOMA | MEN | GENETICS & HEREDITY | RISK | JAPANESE | MYOSIN VI | 22Q13 | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Prostatic Neoplasms - genetics | Risk Assessment | Humans | Risk Factors | Genetic Loci - genetics | Genotype | Male | Polymorphism, Single Nucleotide | Quantitative trait loci | Genetic aspects | Prostate cancer | Identification and classification | Health aspects | Risk factors | Studies | Genealogy | Men | Genomes | Health risk assessment | Meta-analysis
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4. Full Text Multiple newly identified loci associated with prostate cancer susceptibility
by Eeles, Rosalind A and Kote-Jarai, Zsofia and Giles, Graham G and Olama, Ali Amin Al and Guy, Michelle and Jugurnauth, Sarah K and Mulholland, Shani and Leongamornlert, Daniel A and Edwards, Stephen M and Morrison, Jonathan and Field, Helen I and Southey, Melissa C and Severi, Gianluca and Donovan, Jenny L and Hamdy, Freddie C and Dearnaley, David P and Muir, Kenneth R and Smith, Charmaine and Bagnato, Melisa and Ardern-Jones, Audrey T and Hall, Amanda L and O'Brien, Lynne T and Gehr-Swain, Beatrice N and Wilkinson, Rosemary A and Cox, Angie and Lewis, Sarah and Brown, Paul M and Jhavar, Sameer G and Tymrakiewicz, Malgorzata and Lophatananon, Artitaya and Bryant, Sarah L and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Fisher, Cyril and Jamieson, Charles and Cooper, Colin S and English, Dallas R and Hopper, John L and Neal, David E and Easton, Douglas F and British Assoc Urological Surg Sect and Uk Genetic Prostate Canc Study Col and Uk ProtecT Study Collaborators and UK Genetic Prostate Cancer Study Collaborators and UK ProtecT Study Collaborators and British Association of Urological Surgeons' Section of Oncology and The UK Genetic Prostate Cancer Study Collaborators and The UK ProtecT Study Collaborators
Nature Genetics, ISSN 1061-4036, 03/2008, Volume 40, Issue 3, pp. 316 - 321
Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this... 
RISK LOCUS | POLYMORPHISMS | ANTIGEN LEVELS | GENE | VARIANTS | MEN | GENETICS & HEREDITY | AUSTRALIAN CASE-CONTROL | RADICAL PROSTATECTOMY | PROMOTER | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Humans | Middle Aged | Genotype | Male | United Kingdom | Chromosome Mapping | Case-Control Studies | Algorithms | Prostatic Neoplasms - genetics | Aged, 80 and over | Adult | Aged | Polymorphism, Single Nucleotide | Australia | Quantitative Trait Loci | Prostate-specific antigen | Physiological aspects | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Prostate cancer | Health aspects | Risk factors | Genetic markers | Chromosomes | Genomics | Single-nucleotide polymorphism | DNA | Blood | chromosome 3
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5. Full Text Multiple loci on 8q24 associated with prostate cancer susceptibility
by Al Olama, Ali Amin and Kote-Jarai, Zsofia and Giles, Graham G and Guy, Michelle and Morrison, Jonathan and Severi, Gianluca and Leongamornlert, Daniel A and Tymrakiewicz, Malgorzata and Jhavar, Sameer and Saunders, Ed and Hopper, John L and Southey, Melissa C and Muir, Kenneth R and English, Dallas R and Dearnaley, David P and Ardern-Jones, Audrey T and Hall, Amanda L and O'Brien, Lynne T and Wilkinson, Rosemary A and Sawyer, Emma and Lophatananon, Artitaya and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Cooper, Colin and Donovan, Jenny L and Hamdy, Freddie C and Neal, David E and Eeles, Rosalind A and Easton, Douglas F and UK Prostate Testing Canc Treatment and British Assoc Urol Surg Section On and UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology
Nature Genetics, ISSN 1061-4036, 10/2009, Volume 41, Issue 10, pp. 1058 - 1060
Previous studies have identified multiple loci on 8q24 associated with prostate cancer risk. We performed a comprehensive analysis of SNP associations across... 
RISK LOCUS | VARIANTS | COLORECTAL-CANCER | MYC | GENETICS & HEREDITY | AMERICANS | RS6983267 | GENOME-WIDE ASSOCIATION | Genome-Wide Association Study | Disease Susceptibility | Prostatic Neoplasms - genetics | Humans | Risk Factors | Genotype | Male | Chromosomes, Human, Pair 8 | Polymorphism, Single Nucleotide | Genome, Human | Quantitative trait loci | Care and treatment | Disease susceptibility | Genetic aspects | Research | Diagnosis | Single nucleotide polymorphisms | Health aspects | Prostate cancer | Identification and classification | Risk factors | Genetics | Regression analysis | Binding sites | Colorectal cancer
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6. Full Text Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
by Eeles, R.A and Kote Jarai, Z and Al Olama, A.A and Giles, G.G and Guy, M and Severi, G and Muir, K and Hopper, J.L and Henderson, B.E and Haiman, C.A and Schleutker, J and Hamdy, F.C and Neal, D.E and Donovan, J.L and Stanford, J.L and Ostrander, E.A and Ingles, S.A and John, E.M and Thibodeau, S.N and Schaid, D and Park, J.Y and Spurdle, A and Clements, J and Dickinson, J.L and Maier, C and Vogel, W and Dork, T and Rebbeck, T.R and Cooney, K.A and Cannon Albright, L and Chappuis, P.O and Hutter, P and Zeegers, M and Kaneva, R and Zhang, H.W and Lu, Y.J and Foulkes, WD and English, D.R and Leongamornlert, D.A and Tymrakiewicz, M and Morrison, J and Ardern Jones, A.T and Hall, A.L and O'Brien, L.T and Wilkinson, R.A and Saunders, E.J and Page, E.C and Sawyer, E.J and Edwards, S.M and Dearnaley, D.P and Horwich, A and Huddart, R.A and Khoo, V.S and Parker, C.C and Van As, N and Woodhouse, C.J and Thompson, A and Christmas, T and Ogden, C and Cooper, C.S and Southey, M.C and Lophatananon, A and Liu, J.F and Kolonel, L.N and Le Marchand, L and Wahlfors, T and Tammela, T.L and Auvinen, A and Lewis, S.J and Cox, A and FitzGerald, L.M and Koopmeiners, J.S and Karyadi, D.M and Kwon, E.M and Stern, M.C and Corral, R and Joshi, A.D and Shahabi, A and McDonnell, S.K and Sellers, T.A and Pow Sang, J and Chambers, S and Aitken, J and Gardiner, R.A and Batra, J and Kedda, M.A and Lose, F and Polanowski, A and Patterson, B and Serth, J and Meyer, A and Luedeke, M and Stefflova, K and Ray, A.M and Lange, E.M and Farnham, J and Khan, H and Slavov, C and Mitkova, A and British Assoc Urological Surg and PRACTICAL Consortium and UK ProtecT Study Collaborators and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The PRACTICAL Consortium and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators
Nature Genetics, ISSN 1061-4036, 01/2009, Volume 41, Issue 10, pp. 1116 - 21
Prostate cancer (PrCa) is the most frequently diagnosed cancer in males in developed countries. To identify common PrCa susceptibility alleles, we previously... 
RISK | AUSTRALIAN CASE-CONTROL | VARIANTS | MULTIPLE | GENETICS & HEREDITY | ANTIGEN | Genome-Wide Association Study | Disease Susceptibility | Prostatic Neoplasms - genetics | Humans | Genotype | Male | Chromosomes, Human | Polymorphism, Single Nucleotide | Genome, Human | Disease susceptibility | Genetic aspects | Research | Diagnosis | Single nucleotide polymorphisms | Health aspects | Prostate cancer | Risk factors | Studies | Medical research | Inflation | Regression analysis | Chromosomes
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7. Full Text Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
by Kote-Jarai, Zsofia and Olama, Ali Amin Al and Giles, Graham G and Severi, Gianluca and Schleutker, Johanna and Weischer, Maren and Campa, Daniele and Riboli, Elio and Key, Tim and Gronberg, Henrik and Hunter, David J and Kraft, Peter and Thun, Michael J and Ingles, Sue and Chanock, Stephen and Albanes, Demetrius and Hayes, Richard B and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Pharoah, Paul and Schumacher, Fredrick and Henderson, Brian E and Stanford, Janet L and Ostrander, Elaine A and Sorensen, Karina Dalsgaard and Dörk, Thilo and Andriole, Gerald and Dickinson, Joanne L and Cybulski, Cezary and Lubinski, Jan and Spurdle, Amanda and Clements, Judith A and Chambers, Suzanne and Aitken, Joanne and Gardiner, R. A. Frank and Thibodeau, Stephen N and Schaid, Dan and John, Esther M and Maier, Christiane and Vogel, Walther and Cooney, Kathleen A and Park, Jong Y and Cannon-Albright, Lisa and Brenner, Hermann and Habuchi, Tomonori and Zhang, Hong-Wei and Lu, Yong-Jie and Kaneva, Radka and Muir, Ken and Benlloch, Sara and Leongamornlert, Daniel A and Saunders, Edward J and Tymrakiewicz, Malgorzata and Mahmud, Nadiya and Guy, Michelle and O'Brien, Lynne T and Wilkinson, Rosemary A and Hall, Amanda L and Sawyer, Emma J and Dadaev, Tokhir and Morrison, Jonathan and Dearnaley, David P and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Van As, Nicholas and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Cooper, Colin S and Lophatonanon, Aritaya and Southey, Melissa C and Hopper, John L and English, Dallas R and Wahlfors, Tiina and Tammela, Teuvo L. J and Klarskov, Peter and Nordestgaard, Børge G and Røder, M Andreas and Tybjarg-Hansen, Anne and Bojesen, Stig E and Travis, Ruth and Canzian, Federico and Kaaks, Rudolf and Wiklund, Fredrik and Aly, Markus and Lindstrom, Sara and Diver, W Ryan and Gapstur, Susan and Stern, Mariana C and Corral, Roman and Virtamo, Jarmo and Cox, Angela and Haiman, Christopher A and Le Marchand, Loic and Fitzgerald, Liesel and Kolb, Suzanne and ... and UK ProtecT Study Collaborators and Australian Prostate Canc BioResour and PRACTCTICAL Consortium and UK Genetic Prostate Canc Study Col and PRACTICAL Consortium and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource and The PRACTICAL Consortium and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource
Nature Genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 785 - 791
Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. We conducted a multi-stage genome-wide association study for PrCa... 
SEQUENCE VARIANTS | GENETICS & HEREDITY | Genome-Wide Association Study | Disease Susceptibility | Chromosomes, Human - genetics | Humans | Middle Aged | Genotype | Male | Case-Control Studies | Randomized Controlled Trials as Topic | Prostatic Neoplasms - genetics | Telomerase - genetics | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Genome, Human | Cohort Studies | Disease susceptibility | Genomes | Genetic aspects | Research | Single nucleotide polymorphisms | Prostate cancer | Risk factors | Genetics | Gene loci | Regression analysis
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