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Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4376 - 4387
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2015, Volume 27, Issue 3, pp. 409 - 425
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2017, Volume 23, Issue 6, pp. 1481 - 1492
Journal Article
Oncogene, ISSN 0950-9232, 02/2019, Volume 38, Issue 8, pp. 1200 - 1210
Certain cancers, including gastrointestinal stromal tumor (GIST) and subsets of melanoma, are caused by somatic KIT mutations that result in KIT receptor... 
PROTEIN PHOSPHATASE-1 | GENE-MUTATIONS | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-KIT | PHASE-II | CELL BIOLOGY | ONCOLOGY | THERAPEUTIC TARGET | MOUSE MODEL | GENETICS & HEREDITY | DOSE IMATINIB | GASTROINTESTINAL STROMAL TUMORS | IMATINIB MESYLATE | RNA, Small Interfering - genetics | Membrane Proteins - genetics | Humans | Protein-Serine-Threonine Kinases - genetics | Melanoma - pathology | Proto-Oncogene Proteins c-kit - antagonists & inhibitors | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Mutation - drug effects | Gastrointestinal Stromal Tumors - drug therapy | Melanoma - genetics | Gastrointestinal Stromal Tumors - pathology | Melanoma - drug therapy | Imatinib Mesylate - administration & dosage | Cell Line, Tumor | Proto-Oncogene Proteins c-kit - genetics | Mice | Gastrointestinal Stromal Tumors - genetics | Care and treatment | Gastrointestinal cancer | Melanoma | Development and progression | Genetic aspects | Gene expression | Phosphotransferases | Health aspects | Oncogenes | Tyrosine | Therapeutic applications | siRNA | Drug resistance | Genetic screening | Chemotherapy | Cell death | Xenografts | Protein-tyrosine kinase receptors | Mutation | Protein-tyrosine kinase | Cancer | LMTK3 | melanoma | GIST | KIT | TKI-resistance
Journal Article
Journal Article
ONCOGENE, ISSN 0950-9232, 08/2019, Volume 38, Issue 34, pp. 6196 - 6210
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 4, pp. 505 - 511
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer diagnosed in more than 200,000 women each year(1) and is recalcitrant to... 
MEDICINE, RESEARCH & EXPERIMENTAL | PHOSPHATASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHASE-II | IDENTIFICATION | CELL BIOLOGY | TRIAL | BASAL-LIKE | PROGNOSTIC-FACTOR | NONRECEPTOR TYPE 12 | PROTEIN COMPLEXES | EXPRESSION | CARCINOMA | Sunitinib - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 12 - metabolism | Phosphorylation | Crizotinib - therapeutic use | Signal Transduction | Cell Survival | Humans | Protein Tyrosine Phosphatase, Non-Receptor Type 12 - genetics | Receptors, Cell Surface - metabolism | Mutation - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Receptors, Cell Surface - antagonists & inhibitors | Triple Negative Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Sunitinib - therapeutic use | Mice, Nude | Crizotinib - pharmacology | Triple Negative Breast Neoplasms - pathology | Cell Line, Tumor | Female | Triple Negative Breast Neoplasms - enzymology | Care and treatment | Cell receptors | Gene mutations | Development and progression | Esterases | Breast cancer | Genetic aspects | Gene expression | Health aspects | Tyrosine | Epidermal growth factor receptors | Substrate inhibition | Regression analysis | Kinases | Signaling | Receptors | Inhibitors | Addiction | Feedback | Breast | Tumor suppressor genes | Strategy | Mutation | Combinatorial analysis | Cancer | Protein-tyrosine-phosphatase | Tumors | Apoptosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2017, Volume 114, Issue 15, pp. 3981 - 3986
ZBTB transcription factors orchestrate gene transcription during tissue development. However, their roles in glioblastoma (GBM) remain unexplored. Here,... 
BCL6 | NCoR | AXL | Glioblastoma multiforme | ZBTB | glioblastoma multiforme | MULTIDISCIPLINARY SCIENCES | CELL-GROWTH | BTB DOMAIN | BREAST-CANCER | B-CELLS | IN-VITRO | GROWTH ARREST | PROBE LEVEL | INHIBITOR | HUMAN GLIOBLASTOMA-MULTIFORME | Biological Sciences
Journal Article
Journal of Hematology and Oncology, ISSN 1756-8722, 11/2017, Volume 10, Issue 1, pp. 173 - 13
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2014, Volume 111, Issue 17, pp. 6383 - 6388
Alveolar rhabdomyosarcoma (aRMS) is an aggressive myogenic childhood malignancy, not infrequently presenting as incurable metastatic disease. To identify... 
Receptors | Phosphorylation | Small interfering RNA | Ligands | Mice | Arm | Viability | Tumors | Cancer | Apoptosis | Sarcoma | Pediatric | Muscle | SURVIVAL | CELLS | sarcoma | COLORECTAL-CANCER PROGRESSION | MULTIDISCIPLINARY SCIENCES | TYROSINE KINASES | IDENTIFICATION | pediatric | INHIBITION | muscle | THERAPEUTIC TARGET | GROWTH-FACTORS | TUMOR-GROWTH | EXPRESSION | RNA Interference - drug effects | Prognosis | Apoptosis - drug effects | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Rhabdomyosarcoma, Alveolar - metabolism | Forkhead Transcription Factors - metabolism | Rhabdomyosarcoma, Alveolar - pathology | Benzamides - pharmacology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Cell Survival - drug effects | Dasatinib | Focal Adhesion Protein-Tyrosine Kinases - metabolism | Receptor, EphB4 - antagonists & inhibitors | Pyrimidines - pharmacology | Cell Adhesion - drug effects | Ephrin-B2 - metabolism | Imatinib Mesylate | Piperazines - pharmacology | Receptor, EphB4 - metabolism | Animals | Rhabdomyosarcoma, Alveolar - enzymology | Signal Transduction - drug effects | Cell Proliferation - drug effects | Forkhead Box Protein O1 | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Paired Box Transcription Factors - metabolism | RNA, Small Interfering - metabolism | Receptor Cross-Talk - drug effects | Biological Sciences
Journal Article